Published in Thorax on November 26, 2010
Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality. Thorax (2012) 4.06
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Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated disease. JAMA (2005) 6.87
Renal and retinal effects of enalapril and losartan in type 1 diabetes. N Engl J Med (2009) 6.75
Dopamine agonists and the risk of cardiac-valve regurgitation. N Engl J Med (2007) 6.23
Use of statins and the risk of death in patients with prostate cancer. J Clin Oncol (2013) 5.28
Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality. Thorax (2012) 4.06
Inhaled corticosteroid use in chronic obstructive pulmonary disease and the risk of hospitalization for pneumonia. Am J Respir Crit Care Med (2007) 3.94
The use of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: nested case-control study. BMJ (2012) 3.82
Inhaled corticosteroids in COPD and the risk of serious pneumonia. Thorax (2013) 3.62
Adult Asthma Consensus Guidelines update 2003. Can Respir J (2004) 3.61
Long-term use of antidepressants for depressive disorders and the risk of diabetes mellitus. Am J Psychiatry (2009) 3.33
Proton pump inhibitor use and risk of community-acquired Clostridium difficile-associated disease defined by prescription for oral vancomycin therapy. CMAJ (2006) 3.18
Androgen deprivation therapy and risk of acute kidney injury in patients with prostate cancer. JAMA (2013) 3.16
Increased risk of childhood asthma from antibiotic use in early life. Chest (2007) 3.11
Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetes. BMJ (2010) 3.09
A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis. Arthritis Res Ther (2008) 2.87
Hepatitis B vaccine and the risk of CNS inflammatory demyelination in childhood. Neurology (2008) 2.87
Bronchodilator use and the risk of arrhythmia in COPD: part 1: Saskatchewan cohort study. Chest (2012) 2.65
ACE-I and ARBs in early diabetic nephropathy. J Renin Angiotensin Aldosterone Syst (2002) 2.64
The risk of hospitalized infection in patients with rheumatoid arthritis. J Rheumatol (2008) 2.60
Use of venlafaxine compared with other antidepressants and the risk of sudden cardiac death or near death: a nested case-control study. BMJ (2010) 2.40
Use of first- and second-generation cyclooxygenase-2-selective nonsteroidal antiinflammatory drugs and risk of acute myocardial infarction. Circulation (2006) 2.34
Should combination therapy with inhaled corticosteroids and long-acting beta2-agonists be prescribed as initial maintenance treatment for asthma? CMAJ (2002) 2.30
Antirheumatic drugs and the risk of tuberculosis. Clin Infect Dis (2006) 2.29
Fluoroquinolones and the risk of serious arrhythmia: a population-based study. Clin Infect Dis (2012) 2.17
The risk of herpes zoster in patients with rheumatoid arthritis in the United States and the United Kingdom. Arthritis Rheum (2007) 2.16
Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding. CMAJ (2007) 2.02
Cardiovascular morbidity and mortality in COPD. Chest (2005) 2.01
Benzodiazepines and elderly drivers: a comparison of pharmacoepidemiological study designs. Pharmacoepidemiol Drug Saf (2007) 1.98
Hepatitis B vaccination and the risk of childhood-onset multiple sclerosis. Arch Pediatr Adolesc Med (2007) 1.96
Discontinuation of statin therapy following an acute myocardial infarction: a population-based study. Eur Heart J (2008) 1.94
Patterns of antibiotic use and risk of hospital admission because of Clostridium difficile infection. CMAJ (2008) 1.91
Natural history of multiple sclerosis with childhood onset. N Engl J Med (2007) 1.89
Underreporting exacerbation of chronic obstructive pulmonary disease in a longitudinal cohort. Am J Respir Crit Care Med (2007) 1.85
The nested case-control study in cardiology. Am Heart J (2003) 1.84
The early natural history of nephropathy in Type 1 Diabetes: III. Predictors of 5-year urinary albumin excretion rate patterns in initially normoalbuminuric patients. Diabetes (2005) 1.67
The use of inhaled corticosteroids and the risk of adrenal insufficiency. Eur Respir J (2012) 1.67
Inhaled corticosteroids and the risks of diabetes onset and progression. Am J Med (2010) 1.66
Canadian Pediatric Asthma Consensus guidelines, 2003 (updated to December 2004): introduction. CMAJ (2005) 1.63
The concurrent use of antithrombotic therapies and the risk of bleeding in patients with atrial fibrillation. Thromb Haemost (2013) 1.53
Airway remodeling in subjects with severe asthma with or without chronic persistent airflow obstruction. J Allergy Clin Immunol (2009) 1.52
Differences in airway remodeling between subjects with severe and moderate asthma. J Allergy Clin Immunol (2005) 1.52
Acute disseminated encephalomyelitis cohort study: prognostic factors for relapse. Eur J Paediatr Neurol (2006) 1.49
First episode of acute CNS inflammatory demyelination in childhood: prognostic factors for multiple sclerosis and disability. J Pediatr (2004) 1.48
Use of lithium and the risk of injurious motor vehicle crash in elderly adults: case-control study nested within a cohort. BMJ (2004) 1.44
The utility of the Health Plan Employer Data and Information Set (HEDIS) asthma measure to predict asthma-related outcomes. Ann Allergy Asthma Immunol (2004) 1.44
Airway inflammation assessed by invasive and noninvasive means in severe asthma: eosinophilic and noneosinophilic phenotypes. J Allergy Clin Immunol (2006) 1.43
Immediate and delayed impact of oral glucocorticoid therapy on risk of serious infection in older patients with rheumatoid arthritis: a nested case-control analysis. Ann Rheum Dis (2012) 1.43
The use of metformin and the incidence of lung cancer in patients with type 2 diabetes. Diabetes Care (2012) 1.42
Bronchodilator use and the risk of arrhythmia in COPD: part 2: reassessment in the larger Quebec cohort. Chest (2012) 1.42
The relationship of diabetic retinopathy to preclinical diabetic glomerulopathy lesions in type 1 diabetic patients: the Renin-Angiotensin System Study. Diabetes (2005) 1.40
Increased expression of ADAM33 and ADAM8 with disease progression in asthma. J Allergy Clin Immunol (2007) 1.40
Metformin and the incidence of prostate cancer in patients with type 2 diabetes. Cancer Epidemiol Biomarkers Prev (2010) 1.39
Antibiotics in primary prevention of stroke in the elderly. Stroke (2003) 1.39
Cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs and the risk of ischemic stroke: a nested case-control study. Stroke (2006) 1.38
Androgen-deprivation therapy and the risk of stroke in patients with prostate cancer. Eur Urol (2011) 1.37
Point: were industry-sponsored roflumilast trials appropriate? Yes. Chest (2014) 1.36
Differences in airway cytokine profile in severe asthma compared to moderate asthma. Chest (2007) 1.36
Implementing practice guidelines: a workshop on guidelines dissemination and implementation with a focus on asthma and COPD. Can Respir J (2006) 1.32
Transdermal and oral hormone replacement therapy and the risk of stroke: a nested case-control study. BMJ (2010) 1.32
MRI prognostic factors for relapse after acute CNS inflammatory demyelination in childhood. Brain (2004) 1.31
Incretin based drugs and risk of acute pancreatitis in patients with type 2 diabetes: cohort study. BMJ (2014) 1.27
Proton pump inhibitors and the risk of hospitalisation for community-acquired pneumonia: replicated cohort studies with meta-analysis. Gut (2013) 1.26
Geographic and gender variability in the prevalence of bronchial responsiveness in Canada. Chest (2004) 1.26
CNODES: the Canadian Network for Observational Drug Effect Studies. Open Med (2012) 1.26
The impact of hepatitis C virus coinfection on HIV progression before and after highly active antiretroviral therapy. J Acquir Immune Defic Syndr (2003) 1.24
Nonsteroidal anti-inflammatory drug use and the risk of severe skin and soft tissue complications in patients with varicella or zoster disease. Br J Clin Pharmacol (2008) 1.23
Incidence of and mortality from venous thromboembolism in a real-world population: the Q-VTE Study Cohort. Am J Med (2013) 1.22
The case-crossover study design in pharmacoepidemiology. Stat Methods Med Res (2008) 1.21
Association Between Incretin-Based Drugs and the Risk of Acute Pancreatitis. JAMA Intern Med (2016) 1.21
Trends in the prescription of anti-diabetic medications in the United Kingdom: a population-based analysis. Pharmacoepidemiol Drug Saf (2009) 1.19
Prevalence of obstructive sleep apnea-hypopnea in severe versus moderate asthma. J Allergy Clin Immunol (2009) 1.18
Mortality after infection with methicillin-resistant Staphylococcus aureus (MRSA) diagnosed in the community. BMC Med (2008) 1.18
Childhood predictors of smoking in adolescence: a follow-up study of Montreal schoolchildren. CMAJ (2005) 1.16
Bias in observational study of the effectiveness of nasal corticosteroids in asthma. J Allergy Clin Immunol (2005) 1.14
Risks of pneumonia in patients with asthma taking inhaled corticosteroids. Am J Respir Crit Care Med (2010) 1.12
Lifestyle variables and the risk of myocardial infarction in the general practice research database. BMC Cardiovasc Disord (2007) 1.12
Rheumatoid arthritis, its treatments, and the risk of tuberculosis in Quebec, Canada. Arthritis Rheum (2009) 1.10
Implementation of a targeted screening program to detect airflow obstruction suggestive of chronic obstructive pulmonary disease within a presurgical screening clinic. Can Respir J (2015) 1.09
Hematologic malignant neoplasms after drug exposure in rheumatoid arthritis. Arch Intern Med (2008) 1.09
Secular trends of antibacterial prescribing in UK paediatric primary care. J Antimicrob Chemother (2010) 1.08
Inhaled and nasal corticosteroid use and the risk of fracture. Am J Respir Crit Care Med (2003) 1.07
Body mass index (BMI) and waist circumference (WC) as screening tools for cardiovascular risk factors in Guadeloupean women. J Clin Epidemiol (2002) 1.06
Antimicrobial drugs and community-acquired Clostridium difficile-associated disease, UK. Emerg Infect Dis (2007) 1.06
The association between systemic glucocorticoid therapy and the risk of infection in patients with rheumatoid arthritis: systematic review and meta-analyses. Arthritis Res Ther (2011) 1.04
T Cells localize with proliferating smooth muscle alpha-actin+ cell compartments in asthma. Am J Respir Crit Care Med (2010) 1.04
Gastro-intestinal haemorrhage risks of selective serotonin receptor antagonist therapy: a new look. Br J Clin Pharmacol (2008) 1.02
Parental smoking at home and the risk of childhood-onset multiple sclerosis in children. Brain (2007) 1.01
Demyelinating events in rheumatoid arthritis after drug exposures. Ann Rheum Dis (2009) 1.00
Estrogen therapy and risk of cognitive decline: results from the Women's Estrogen for Stroke Trial (WEST). Am J Obstet Gynecol (2005) 1.00
Warfarin use and the risk of motor vehicle crash in older drivers. Br J Clin Pharmacol (2006) 1.00