Published in BMC Nephrol on September 29, 2003
Vascular ossification-calcification in metabolic syndrome, type 2 diabetes mellitus, chronic kidney disease, and calciphylaxis-calcific uremic arteriolopathy: the emerging role of sodium thiosulfate. Cardiovasc Diabetol (2005) 1.59
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C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med (2000) 18.04
Renal insufficiency as a predictor of cardiovascular outcomes and the impact of ramipril: the HOPE randomized trial. Ann Intern Med (2001) 6.38
Calciphylaxis is usually non-ulcerating: risk factors, outcome and therapy. Kidney Int (2002) 4.38
The serum protein alpha 2-Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification. J Clin Invest (2003) 3.71
Calciphylaxis: emerging concepts in prevention, diagnosis, and treatment. Semin Dial (2002) 2.16
Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein-deficient mice: evidence for osteopontin as an inducible inhibitor of vascular calcification in vivo. J Exp Med (2002) 1.67
Wet gangrene in hemodialysis patients with calciphylaxisis is associated with a poor prognosis. Cardiovasc Surg (2001) 1.47
Cardiovascular calcification in patients with end-stage renal disease: a century-old phenomenon. Kidney Int Suppl (2002) 1.34
Novel insights into uremic vascular calcification: role of matrix Gla protein and alpha-2-Heremans Schmid glycoprotein/fetuin. Blood Purif (2002) 1.06
Painful ulcers in calciphylaxis - combined treatment with maggot therapy and oral pentoxyfillin. J Dermatolog Treat (2001) 0.94
The management of thyroid nodules: a retrospective analysis of health insurance data. Dtsch Arztebl Int (2013) 2.97
American Association of Clinical Endocrinologists, Associazione Medici Endocrinologi, and EuropeanThyroid Association Medical Guidelines for Clinical Practice for the Diagnosis and Management of Thyroid Nodules. Endocr Pract (2010) 2.97
Pituitary adenoma predisposition caused by germline mutations in the AIP gene. Science (2006) 2.24
Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes. Biochem Biophys Res Commun (2002) 1.86
Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes. Biochem Biophys Res Commun (2003) 1.82
Effect of a 4 week physical training program on plasma concentrations of inflammatory markers in patients with abnormal glucose tolerance. Eur J Endocrinol (2006) 1.76
Evaluation of small-molecule modulators of the luteinizing hormone/choriogonadotropin and thyroid stimulating hormone receptors: structure-activity relationships and selective binding patterns. J Med Chem (2006) 1.71
Altered fiber distribution and fiber-specific glycolytic and oxidative enzyme activity in skeletal muscle of patients with type 2 diabetes. Diabetes Care (2006) 1.63
A low molecular weight agonist signals by binding to the transmembrane domain of thyroid-stimulating hormone receptor (TSHR) and luteinizing hormone/chorionic gonadotropin receptor (LHCGR). J Biol Chem (2006) 1.38
Molecular pathogenesis of euthyroid and toxic multinodular goiter. Endocr Rev (2004) 1.33
Clinical characteristics and therapeutic responses in patients with germ-line AIP mutations and pituitary adenomas: an international collaborative study. J Clin Endocrinol Metab (2010) 1.24
Isoproterenol, TNFalpha, and insulin downregulate adipose triglyceride lipase in 3T3-L1 adipocytes. Mol Cell Endocrinol (2005) 1.20
Analysis of the relationship between the Pro12Ala variant in the PPAR-gamma2 gene and the response rate to therapy with pioglitazone in patients with type 2 diabetes. Diabetes Care (2003) 1.17
Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations. Proc Natl Acad Sci U S A (2007) 1.16
Interleukin-6 is a negative regulator of visfatin gene expression in 3T3-L1 adipocytes. Am J Physiol Endocrinol Metab (2005) 1.15
Pancreatic neuroendocrine tumor with ectopic adrenocorticotropin production upon second recurrence. J Clin Endocrinol Metab (2004) 1.14
Identification of a novel epitope in the thyroid-stimulating hormone receptor ectodomain acting as intramolecular signaling interface. J Biol Chem (2004) 1.14
Hypercalcemia as a result of sarcoidosis with normal serum concentrations of vitamin D. Med Sci Monit (2007) 1.11
Contacts between extracellular loop two and transmembrane helix six determine basal activity of the thyroid-stimulating hormone receptor. J Biol Chem (2006) 1.08
Monocyte chemoattractant protein 1 expression is stimulated by growth hormone and interleukin-6 in 3T3-L1 adipocytes. Biochem Biophys Res Commun (2004) 1.07
Current state and future perspective of molecular diagnosis of fine-needle aspiration biopsy of thyroid nodules. J Clin Endocrinol Metab (2011) 1.06
Adiponectin, obesity, and cardiovascular disease. Biochimie (2004) 1.05
Extended hormone binding site of the human thyroid stimulating hormone receptor: distinctive acidic residues in the hinge region are involved in bovine thyroid stimulating hormone binding and receptor activation. J Biol Chem (2008) 1.03
Molecular fine-needle aspiration biopsy diagnosis of thyroid nodules by tumor specific mutations and gene expression patterns. Mol Cell Endocrinol (2010) 1.02
Interleukin-6 is a positive regulator of tumor necrosis factor alpha-induced adipose-related protein in 3T3-L1 adipocytes. FEBS Lett (2004) 1.00
Structural determinants for G-protein activation and specificity in the third intracellular loop of the thyroid-stimulating hormone receptor. J Mol Med (Berl) (2006) 0.98
Pharmacokinetics of alpha-lipoic acid in subjects with severe kidney damage and end-stage renal disease. J Clin Pharmacol (2005) 0.97
Mechanisms of disease: hydrogen peroxide, DNA damage and mutagenesis in the development of thyroid tumors. Nat Clin Pract Endocrinol Metab (2007) 0.97
Functional desensitization of the extracellular calcium-sensing receptor is regulated via distinct mechanisms: role of G protein-coupled receptor kinases, protein kinase C and beta-arrestins. Endocrinology (2007) 0.97
Hormonal regulation of the novel adipocytokine visfatin in 3T3-L1 adipocytes. J Endocrinol (2005) 0.97
Impact of molecular screening for point mutations and rearrangements in routine air-dried fine-needle aspiration samples of thyroid nodules. Thyroid (2013) 0.97
Ectopic Cushing' syndrome caused by a neuroendocrine carcinoma of the mesentery. BMC Cancer (2006) 0.96
Analysis options for high-throughput sequencing in miRNA expression profiling. BMC Res Notes (2014) 0.96
The superagonistic activity of bovine thyroid-stimulating hormone (TSH) and the human TR1401 TSH analog is determined by specific amino acids in the hinge region of the human TSH receptor. J Biol Chem (2009) 0.96
Significance of ectodomain cysteine boxes 2 and 3 for the activation mechanism of the thyroid-stimulating hormone receptor. J Biol Chem (2006) 0.95
A multi-gene approach to differentiate papillary thyroid carcinoma from benign lesions: gene selection using support vector machines with bootstrapping. Endocr Relat Cancer (2007) 0.95
Perspectives and limitations of microarray-based gene expression profiling of thyroid tumors. Endocr Rev (2007) 0.95
Somatic VHL gene alterations in MEN2-associated medullary thyroid carcinoma. BMC Cancer (2006) 0.93
The human thyrotropin receptor is predominantly internalized by beta-arrestin 2. Endocrinology (2006) 0.93
Evidence for cooperative signal triggering at the extracellular loops of the TSH receptor. FASEB J (2008) 0.93
Similar prevalence of somatic TSH receptor and Gsalpha mutations in toxic thyroid nodules in geographical regions with different iodine supply in Turkey. Eur J Endocrinol (2006) 0.93
Selenium and goiter prevalence in borderline iodine sufficiency. Eur J Endocrinol (2006) 0.93
Evaluation of a computer based interactive diabetes education program designed to train the estimation of the energy or carbohydrate contents of foods. Patient Educ Couns (2002) 0.92
Large genomic deletions in AIP in pituitary adenoma predisposition. J Clin Endocrinol Metab (2008) 0.92
Regulation of adiponectin receptor R1 and R2 gene expression in adipocytes of C57BL/6 mice. Biochem Biophys Res Commun (2005) 0.91
The hinge region: an important receptor component for GPHR function. Trends Endocrinol Metab (2009) 0.91
Is there a place for thyroidectomy in older patients with thyrotoxic storm and cardiorespiratory failure? Thyroid (2003) 0.91
Tissue inhibitor of metalloproteinase-1 predicts adiposity in humans. Eur J Endocrinol (2007) 0.90
Perspectives for improved and more accurate classification of thyroid epithelial tumors. J Clin Endocrinol Metab (2008) 0.90
Modulation of TSHR signaling by posttranslational modifications. Trends Endocrinol Metab (2007) 0.89
Functional significance of the thyrotropin receptor germline polymorphism D727E. Biochem Biophys Res Commun (2003) 0.89
A hydrophobic cluster in the center of the third extracellular loop is important for thyrotropin receptor signaling. Endocrinology (2005) 0.88
Growth hormone is a positive regulator of adiponectin receptor 2 in 3T3-L1 adipocytes. FEBS Lett (2004) 0.88
Impaired enteral levothyroxine absorption in hypothyroidism refractory to oral therapy after thyroid ablation for papillary thyroid cancer: case report and kinetic studies. Thyroid (2006) 0.87
Two novel mutations in the sixth transmembrane segment of the thyrotropin receptor gene causing hyperfunctioning thyroid nodules. Thyroid (2005) 0.87
Principles and determinants of G-protein coupling by the rhodopsin-like thyrotropin receptor. PLoS One (2010) 0.87
Interactions between the extracellular domain and the extracellular loops as well as the 6th transmembrane domain are necessary for TSH receptor activation. Eur J Endocrinol (2005) 0.86
Genetics and phenomics of inherited and sporadic non-autoimmune hyperthyroidism. Mol Cell Endocrinol (2010) 0.85
RET germline mutation in codon 791 in a family representing 3 generations from age 5 to age 70 years: should thyroidectomy be performed? Endocr Pract (2004) 0.85
Gene expression analysis reveals evidence for increased expression of cell cycle-associated genes and Gq-protein-protein kinase C signaling in cold thyroid nodules. J Clin Endocrinol Metab (2004) 0.85
Serum amyloid A3 expression is stimulated by dexamethasone and interleukin-6 in 3T3-L1 adipocytes. J Endocrinol (2004) 0.84
Molecular testing of thyroid fine-needle aspirations improves presurgical diagnosis and supports the histologic identification of minimally invasive follicular thyroid carcinomas. Thyroid (2015) 0.84
Inverse correlation of miRNA and cell cycle-associated genes suggests influence of miRNA on benign thyroid nodule tumorigenesis. J Clin Endocrinol Metab (2012) 0.84
Meta- and reanalysis of gene expression profiles of hot and cold thyroid nodules and papillary thyroid carcinoma for gene groups. J Clin Endocrinol Metab (2006) 0.84
Structural determinants for g protein activation and selectivity in the second intracellular loop of the thyrotropin receptor. Endocrinology (2004) 0.84
Somatic mutations in thyroid nodular disease. Mol Genet Metab (2002) 0.84
Aryl hydrocarbon receptor interacting protein (AIP) gene mutation analysis in children and adolescents with sporadic pituitary adenomas. Clin Endocrinol (Oxf) (2008) 0.84
Cases of borderline in vitro constitutive thyrotropin receptor activity: how to decide whether a thyrotropin receptor mutation is constitutively active or not? Thyroid (2009) 0.83
Relative quantification of indium-111 pentetreotide and gallium-68 DOTATOC uptake in the thyroid gland and association with thyroid pathologies. Thyroid (2009) 0.83
Gene expression analysis reveals evidence for inactivation of the TGF-beta signaling cascade in autonomously functioning thyroid nodules. Oncogene (2004) 0.83
Defining structural and functional dimensions of the extracellular thyrotropin receptor region. J Biol Chem (2011) 0.83
A patient with a large recurrent pheochromocytoma demonstrating the pitfalls of diagnosis. Nat Rev Endocrinol (2011) 0.83
Lack of correlation for sodium iodide symporter mRNA and protein expression and analysis of sodium iodide symporter promoter methylation in benign cold thyroid nodules. Thyroid (2004) 0.83
Detection of PAX8/PPARG and RET/PTC rearrangements is feasible in routine air-dried fine needle aspiration smears. Thyroid (2012) 0.82
Therapeutic perspectives of adipocytokines. Expert Opin Pharmacother (2005) 0.82
Novel thyrotropin receptor germline mutation (Ile568Val) in a Saxonian family with hereditary nonautoimmune hyperthyroidism. Thyroid (2005) 0.82
Comparative analysis of conventional and an adaptive computer-based hypoglycaemia education programs. Patient Educ Couns (2004) 0.81
Molecular differential diagnosis of follicular thyroid carcinoma and adenoma based on gene expression profiling by using formalin-fixed paraffin-embedded tissues. BMC Med Genomics (2013) 0.81
RGS 2 expression is regulated by TSH and inhibits TSH receptor signaling. Eur J Endocrinol (2004) 0.81
Thyroid hormone resistance without mutations in thyroid hormone receptor beta. Med Sci Monit (2007) 0.81
Negative regulation of adipose-expressed galectin-12 by isoproterenol, tumor necrosis factor alpha, insulin and dexamethasone. Eur J Endocrinol (2002) 0.81
Proinflammatory adipocytokines induce TIMP-1 expression in 3T3-L1 adipocytes. FEBS Lett (2005) 0.80
Identification of novel TSH interaction sites by systematic binding analysis of the TSHR hinge region. Endocrinology (2011) 0.80
Growth hormone induces apelin mRNA expression and secretion in mouse 3T3-L1 adipocytes. Regul Pept (2006) 0.80
Expression of G(alpha)(s) proteins and TSH receptor signalling in hyperfunctioning thyroid nodules with TSH receptor mutations. Eur J Endocrinol (2002) 0.80
Lack of in vitro constitutive activity for four previously reported TSH receptor mutations identified in patients with nonautoimmune hyperthyroidism and hot thyroid carcinomas. Clin Endocrinol (Oxf) (2010) 0.80
Toward the application of proteomics to human thyroid tissue. Thyroid (2006) 0.80
Increased expression of G-protein-coupled receptor kinases 3 and 4 in hyperfunctioning thyroid nodules. J Endocrinol (2004) 0.80
[New ultrasound and molecular aspects of thyroid nodule diagnostics]. MMW Fortschr Med (2013) 0.79
Thyroglobulin mRNA quantification in the peripheral blood is not a reliable marker for the follow-up of patients with differentiated thyroid cancer. Eur J Endocrinol (2002) 0.79
Recurrent EZH1 mutations are a second hit in autonomous thyroid adenomas. J Clin Invest (2016) 0.79
Calcium signaling of thyrocytes is modulated by TSH through calcium binding protein expression. Biochim Biophys Acta (2010) 0.79
The genetics of euthyroid familial goiter. Trends Endocrinol Metab (2005) 0.78
Expression of regulators of g protein signaling mRNA is differentially regulated in hot and cold thyroid nodules. Thyroid (2004) 0.78
The thyrotropin receptor mutation database: update 2003. Thyroid (2003) 0.78
Current standards, variations, and pitfalls for the determination of constitutive TSHR activity in vitro. Methods Enzymol (2010) 0.78
Further indications for genetic heterogeneity of euthyroid familial goiter. J Mol Med (Berl) (2003) 0.77
A new silent germline mutation of the TSH receptor: coexpression in a hyperthyroid family member with a second activating somatic mutation. Thyroid (2008) 0.77