Published in Int J Cancer on November 20, 2003
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S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death. Science (2002) 4.13
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Orlistat is a novel inhibitor of fatty acid synthase with antitumor activity. Cancer Res (2004) 2.43
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Profiling constitutive proteolytic events in vivo. Biochem J (2007) 1.78
Enzymes that counteract nitrosative stress promote fungal virulence. Curr Biol (2003) 1.75
Maintenance of nitric oxide and redox homeostasis by the salmonella flavohemoglobin hmp. J Biol Chem (2006) 1.58
Clinical outcomes of two different types of open-door laminoplasties for cervical compressive myelopathy: a prospective study. Neurol India (2012) 1.53
Anterior decompression and nonstructural bone grafting and posterior fixation for cervical facet dislocation with traumatic disc herniation. Spine (Phila Pa 1976) (2012) 1.51
Cleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinase. Biochem J (2006) 1.49
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Two-stage vertebral column resection for severe and rigid scoliosis in patients with low body weight. Spine J (2012) 1.39
The abnormal spindle-like, microcephaly-associated (ASPM) gene encodes a centrosomal protein. Cell Cycle (2005) 1.37
A unique substrate binding mode discriminates membrane type-1 matrix metalloproteinase from other matrix metalloproteinases. J Biol Chem (2002) 1.33
Efficient synthetic inhibitors of anthrax lethal factor. Proc Natl Acad Sci U S A (2005) 1.32
Practical, catalytic, asymmetric synthesis of beta-lactones via a sequential ketene dimerization/hydrogenation process: inhibitors of the thioesterase domain of fatty acid synthase. J Org Chem (2006) 1.26
A genetic analysis of nitrosative stress. Biochemistry (2009) 1.25
An alternative processing of integrin alpha(v) subunit in tumor cells by membrane type-1 matrix metalloproteinase. J Biol Chem (2001) 1.24
Inhibition of fatty-acid synthase induces caspase-8-mediated tumor cell apoptosis by up-regulating DDIT4. J Biol Chem (2008) 1.23
A fatty acid synthase blockade induces tumor cell-cycle arrest by down-regulating Skp2. J Biol Chem (2004) 1.20
Screening for nitric oxide-dependent protein-protein interactions. Science (2003) 1.20
Central carbon metabolism in the progression of mammary carcinoma. Breast Cancer Res Treat (2007) 1.16
Hemivertebrae resection for unbalanced multiple hemivertebrae: is it worth it? Eur Spine J (2013) 1.16
Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma. Oncogene (2003) 1.15
Regulation of T cell priming by lymphoid stroma. PLoS One (2011) 1.14
Matrix metalloproteinase proteolysis of the myelin basic protein isoforms is a source of immunogenic peptides in autoimmune multiple sclerosis. PLoS One (2009) 1.11
A unique substrate recognition profile for matrix metalloproteinase-2. J Biol Chem (2001) 1.10
Inhibition of endothelial cell proliferation and angiogenesis by orlistat, a fatty acid synthase inhibitor. FASEB J (2006) 1.10
Targeting host cell furin proprotein convertases as a therapeutic strategy against bacterial toxins and viral pathogens. J Biol Chem (2007) 1.08
Cleavage preference distinguishes the two-component NS2B-NS3 serine proteinases of Dengue and West Nile viruses. Biochem J (2007) 1.07
Methylation of the retinoid response gene TIG1 in prostate cancer correlates with methylation of the retinoic acid receptor beta gene. Oncogene (2004) 1.07
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Functional specialization in proline biosynthesis of melanoma. PLoS One (2012) 1.06
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Synthesis and optimization of 2-pyridin-3-yl-benzo[d][1,3]oxazin-4-one based inhibitors of human neutrophil elastase. Bioorg Med Chem Lett (2009) 1.05
Lymphocyte development requires S-nitrosoglutathione reductase. J Immunol (2010) 1.05
Genome-wide changes accompanying knockdown of fatty acid synthase in breast cancer. BMC Genomics (2007) 1.05
Inactivation of RAS association domain family 1A gene in cervical carcinomas and the role of human papillomavirus infection. Cancer Res (2003) 1.04
The two-component NS2B-NS3 proteinase represses DNA unwinding activity of the West Nile virus NS3 helicase. J Biol Chem (2008) 1.04
PMAP: databases for analyzing proteolytic events and pathways. Nucleic Acids Res (2008) 1.03
Switching the substrate specificity of the two-component NS2B-NS3 flavivirus proteinase by structure-based mutagenesis. J Virol (2007) 1.02
Proteolysis of the membrane type-1 matrix metalloproteinase prodomain: implications for a two-step proteolytic processing and activation. J Biol Chem (2007) 1.01
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Glutamine-fueled mitochondrial metabolism is decoupled from glycolysis in melanoma. Pigment Cell Melanoma Res (2012) 1.00
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Prevalence of diabetic retinopathy in mainland China: a meta-analysis. PLoS One (2012) 0.98
Platelet mimetic particles for targeting thrombi in flowing blood. Adv Mater (2012) 0.98
Anterior reconstruction with nano-hydroxyapatite/polyamide-66 cage after thoracic and lumbar corpectomy. Orthopedics (2012) 0.96
Structural determinants of limited proteolysis. J Proteome Res (2011) 0.95
Inflammatory proprotein convertase-matrix metalloproteinase proteolytic pathway in antigen-presenting cells as a step to autoimmune multiple sclerosis. J Biol Chem (2009) 0.95
Synthesis of novel beta-lactone inhibitors of fatty acid synthase. J Med Chem (2008) 0.95
Expression and purification of a two-component flaviviral proteinase resistant to autocleavage at the NS2B-NS3 junction region. Protein Expr Purif (2006) 0.95
A residue in the S2 subsite controls substrate selectivity of matrix metalloproteinase-2 and matrix metalloproteinase-9. J Biol Chem (2003) 0.95
TDAG51 mediates epithelial-to-mesenchymal transition in human proximal tubular epithelium. Am J Physiol Renal Physiol (2012) 0.95
Adjacent segment degeneration and disease after lumbar fusion compared with motion-preserving procedures: a meta-analysis. Eur J Orthop Surg Traumatol (2014) 0.93
Comparison of anterior cervical fusion by titanium mesh cage versus nano-hydroxyapatite/polyamide cage following single-level corpectomy. Int Orthop (2013) 0.93
Comparison of anterior and posterior vertebral column resection versus anterior release with posterior internal distraction for severe and rigid scoliosis. Eur Spine J (2014) 0.93
Fabrication of PLGA nanoparticles with a fluidic nanoprecipitation system. J Nanobiotechnology (2010) 0.92
Regulation of DNA repair by S-nitrosylation. Biochim Biophys Acta (2011) 0.92
Targeted deletion of GSNOR in hepatocytes of mice causes nitrosative inactivation of O6-alkylguanine-DNA alkyltransferase and increased sensitivity to genotoxic diethylnitrosamine. Carcinogenesis (2011) 0.91
4EBP1/eIF4E and p70S6K/RPS6 axes play critical and distinct roles in hepatocarcinogenesis driven by AKT and N-Ras proto-oncogenes in mice. Hepatology (2014) 0.90
Rapamycin inhibits transforming growth factor β-induced peritoneal angiogenesis by blocking the secondary hypoxic response. J Cell Mol Med (2012) 0.89
Hepatocarcinogenesis driven by GSNOR deficiency is prevented by iNOS inhibition. Cancer Res (2013) 0.89
Crystal and solution structures of a prokaryotic M16B peptidase: an open and shut case. Structure (2009) 0.88
HDAC inhibitor trichostatin A-inhibited survival of dopaminergic neuronal cells. Neurosci Lett (2009) 0.88
Effect of the decompressive extent on the magnitude of the spinal cord shift after expansive open-door laminoplasty. Spine (Phila Pa 1976) (2011) 0.87
Decreased expression of the human stem cell marker, Rex-1 (zfp-42), in renal cell carcinoma. Carcinogenesis (2005) 0.87
Transgenic expression of entire hepatitis B virus in mice induces hepatocarcinogenesis independent of chronic liver injury. PLoS One (2011) 0.87
Identification of elongation factor 1alpha as a potential associated binding partner for Akt2. Mol Cell Biochem (2006) 0.87
One-stage posterior surgical treatment for lumbosacral tuberculosis with major vertebral body loss and kyphosis. Orthopedics (2013) 0.87
Novel antagonists of the thioesterase domain of human fatty acid synthase. Mol Cancer Ther (2007) 0.87
FK506 neuroprotection after cavernous nerve injury is mediated by thioredoxin and glutathione redox systems. J Sex Med (2011) 0.87
Maspin alters the carcinoma proteome. FASEB J (2005) 0.86
Anterior single segmental decompression and fixation for Denis B type thoracolumbar burst fracture with neurological deficiency: thirty-four cases with average twenty-six month follow-up. Spine (Phila Pa 1976) (2011) 0.86
Total synthesis and comparative analysis of orlistat, valilactone, and a transposed orlistat derivative: Inhibitors of fatty acid synthase. Org Lett (2006) 0.86
Insertion/deletion polymorphisms in the promoter region of BRM contribute to risk of hepatocellular carcinoma in Chinese populations. PLoS One (2013) 0.86
High throughput substrate phage display for protease profiling. Methods Mol Biol (2009) 0.86
Structure-based mutagenesis identifies important novel determinants of the NS2B cofactor of the West Nile virus two-component NS2B-NS3 proteinase. J Gen Virol (2008) 0.85
Revision surgery for spinal tuberculosis with secondary deformity after treatment with debridement, instrumentation, and fusion. Eur Spine J (2014) 0.85
A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma. Cancer Res (2007) 0.85
The tumor suppressor RASSF1A does not interact with Cdc20, an activator of the anaphase-promoting complex. Cell Cycle (2007) 0.85
β-Elemene inhibits the metastasis of B16F10 melanoma cells by downregulation of the expression of uPA, uPAR, MMP-2, and MMP-9. Melanoma Res (2014) 0.85
Anterior and posterior vertebral column resection for severe and rigid idiopathic scoliosis. Eur Spine J (2011) 0.84
Fluorescence properties of twenty fluorescein derivatives: lifetime, quantum yield, absorption and emission spectra. J Fluoresc (2014) 0.84
Analysis of 78 patients with spinal injuries in the 2008 Sichuan, China, earthquake. Orthopedics (2009) 0.84
Proteomic analysis of the role of S-nitrosoglutathione reductase in lipopolysaccharide-challenged mice. Proteomics (2012) 0.84
Optical detection of indocyanine green encapsulated biocompatible poly (lactic-co-glycolic) acid nanoparticles with photothermal optical coherence tomography. Opt Lett (2012) 0.83