Published in Am J Med Sci on November 01, 2007
Hypercalcemia associated with acute kidney injury and metabolic alkalosis. Electrolyte Blood Press (2010) 0.93
RANKL, a necessary chance for clinical application to osteoporosis and cancer-related bone diseases. World J Orthop (2013) 0.90
Peripheral T-cell lymphoma with hypercalcemic crisis as a primary symptom accompanied by polymyositis: A case report and review of the literature. Oncol Lett (2014) 0.78
Establishment of a new murine model of hypercalcemia with anorexia by overexpression of soluble receptor activator of NF-κB ligand using an adenovirus vector. J Bone Miner Metab (2010) 0.77
Milk-alkali syndrome in a middle-aged woman after ingesting large doses of calcium carbonate: a case report. Cases J (2009) 0.75
Pseudohypercalcaemia in mixed cryoglobulinaemia (IgMkappa/polyclonal IgG): a rare complication of Sjögren's syndrome. Clin Rheumatol (2010) 0.75
S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death. Science (2002) 4.13
Mass spectrometry-based label-free quantitative proteomics. J Biomed Biotechnol (2009) 2.72
Orlistat is a novel inhibitor of fatty acid synthase with antitumor activity. Cancer Res (2004) 2.43
CutDB: a proteolytic event database. Nucleic Acids Res (2006) 2.41
Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect. J Biol Chem (2011) 2.24
Polymer particle shape independently influences binding and internalization by macrophages. J Control Release (2010) 2.05
Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation. Mol Cell Biol (2010) 2.05
Profiling constitutive proteolytic events in vivo. Biochem J (2007) 1.78
Cleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinase. Biochem J (2006) 1.49
Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells. Pigment Cell Melanoma Res (2012) 1.46
Substrate cleavage analysis of furin and related proprotein convertases. A comparative study. J Biol Chem (2008) 1.40
HTS identifies novel and specific uncompetitive inhibitors of the two-component NS2B-NS3 proteinase of West Nile virus. Assay Drug Dev Technol (2007) 1.40
A unique substrate binding mode discriminates membrane type-1 matrix metalloproteinase from other matrix metalloproteinases. J Biol Chem (2002) 1.33
Efficient synthetic inhibitors of anthrax lethal factor. Proc Natl Acad Sci U S A (2005) 1.32
Practical, catalytic, asymmetric synthesis of beta-lactones via a sequential ketene dimerization/hydrogenation process: inhibitors of the thioesterase domain of fatty acid synthase. J Org Chem (2006) 1.26
An alternative processing of integrin alpha(v) subunit in tumor cells by membrane type-1 matrix metalloproteinase. J Biol Chem (2001) 1.24
Inhibition of fatty-acid synthase induces caspase-8-mediated tumor cell apoptosis by up-regulating DDIT4. J Biol Chem (2008) 1.23
A fatty acid synthase blockade induces tumor cell-cycle arrest by down-regulating Skp2. J Biol Chem (2004) 1.20
Central carbon metabolism in the progression of mammary carcinoma. Breast Cancer Res Treat (2007) 1.16
Matrix metalloproteinase proteolysis of the myelin basic protein isoforms is a source of immunogenic peptides in autoimmune multiple sclerosis. PLoS One (2009) 1.11
Gene expression profiling of tumor xenografts: In vivo analysis of organ-specific metastasis. Int J Cancer (2003) 1.10
A unique substrate recognition profile for matrix metalloproteinase-2. J Biol Chem (2001) 1.10
Inhibition of endothelial cell proliferation and angiogenesis by orlistat, a fatty acid synthase inhibitor. FASEB J (2006) 1.10
Targeting host cell furin proprotein convertases as a therapeutic strategy against bacterial toxins and viral pathogens. J Biol Chem (2007) 1.08
Cleavage preference distinguishes the two-component NS2B-NS3 serine proteinases of Dengue and West Nile viruses. Biochem J (2007) 1.07
Functional specialization in proline biosynthesis of melanoma. PLoS One (2012) 1.06
Comparative metabolomics of breast cancer. Pac Symp Biocomput (2007) 1.06
Genome-wide changes accompanying knockdown of fatty acid synthase in breast cancer. BMC Genomics (2007) 1.05
The two-component NS2B-NS3 proteinase represses DNA unwinding activity of the West Nile virus NS3 helicase. J Biol Chem (2008) 1.04
PMAP: databases for analyzing proteolytic events and pathways. Nucleic Acids Res (2008) 1.03
Switching the substrate specificity of the two-component NS2B-NS3 flavivirus proteinase by structure-based mutagenesis. J Virol (2007) 1.02
Proteolysis of the membrane type-1 matrix metalloproteinase prodomain: implications for a two-step proteolytic processing and activation. J Biol Chem (2007) 1.01
Glutamine-fueled mitochondrial metabolism is decoupled from glycolysis in melanoma. Pigment Cell Melanoma Res (2012) 1.00
Platelet mimetic particles for targeting thrombi in flowing blood. Adv Mater (2012) 0.98
Structural determinants of limited proteolysis. J Proteome Res (2011) 0.95
Inflammatory proprotein convertase-matrix metalloproteinase proteolytic pathway in antigen-presenting cells as a step to autoimmune multiple sclerosis. J Biol Chem (2009) 0.95
Synthesis of novel beta-lactone inhibitors of fatty acid synthase. J Med Chem (2008) 0.95
Expression and purification of a two-component flaviviral proteinase resistant to autocleavage at the NS2B-NS3 junction region. Protein Expr Purif (2006) 0.95
A residue in the S2 subsite controls substrate selectivity of matrix metalloproteinase-2 and matrix metalloproteinase-9. J Biol Chem (2003) 0.95
Fabrication of PLGA nanoparticles with a fluidic nanoprecipitation system. J Nanobiotechnology (2010) 0.92
4EBP1/eIF4E and p70S6K/RPS6 axes play critical and distinct roles in hepatocarcinogenesis driven by AKT and N-Ras proto-oncogenes in mice. Hepatology (2014) 0.90
Crystal and solution structures of a prokaryotic M16B peptidase: an open and shut case. Structure (2009) 0.88
Novel antagonists of the thioesterase domain of human fatty acid synthase. Mol Cancer Ther (2007) 0.87
Total synthesis and comparative analysis of orlistat, valilactone, and a transposed orlistat derivative: Inhibitors of fatty acid synthase. Org Lett (2006) 0.86
High throughput substrate phage display for protease profiling. Methods Mol Biol (2009) 0.86
Maspin alters the carcinoma proteome. FASEB J (2005) 0.86
Structure-based mutagenesis identifies important novel determinants of the NS2B cofactor of the West Nile virus two-component NS2B-NS3 proteinase. J Gen Virol (2008) 0.85
A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma. Cancer Res (2007) 0.85
Optical detection of indocyanine green encapsulated biocompatible poly (lactic-co-glycolic) acid nanoparticles with photothermal optical coherence tomography. Opt Lett (2012) 0.83
Beta-lactam congeners of orlistat as inhibitors of fatty acid synthase. Bioorg Med Chem Lett (2008) 0.82
Risk modification of colorectal adenoma by CYP7A1 polymorphisms and the role of bile acid metabolism in carcinogenesis. Cancer Prev Res (Phila) (2011) 0.82
Proteins and an inflammatory network expressed in colon tumors. J Proteome Res (2011) 0.81
Competitive interactions of collagen and a jararhagin-derived disintegrin peptide with the integrin alpha2-I domain. J Biol Chem (2008) 0.80
One-step fabrication of polymeric Janus nanoparticles for drug delivery. Langmuir (2012) 0.79
Unusual binding of ursodeoxycholic acid to ileal bile acid binding protein: role in activation of FXRα. J Lipid Res (2012) 0.77
Extracellular and intracellular mechanisms that mediate the metastatic activity of exogenous osteopontin. Cancer (2009) 0.76
Correction: CleavPredict: A Platform for Reasoning about Matrix Metalloproteinases Proteolytic Events. PLoS One (2015) 0.76
Comparative proteomic analysis of a cytosolic fraction from β3 integrin-deficient cells. Cancer Genomics Proteomics (2012) 0.75
TARGETING OF MACROPHAGE FOAM CELLS IN ATHEROSCLEROTIC PLAQUE USING OLIGONUCLEOTIDE-FUNCTIONALIZED NANOPARTICLES. Nano Life (2010) 0.75