Published in J Am Coll Cardiol on October 01, 2003
Inflammatory Pathogenesis of Coronary Atherosclerosis in HIV | NCT02624180
Effect of Probiotic Supplementation on Endothelial Function II | NCT03267758
Predictive value of brachial flow-mediated dilation for incident cardiovascular events in a population-based study: the multi-ethnic study of atherosclerosis. Circulation (2009) 5.26
Cross-sectional relations of digital vascular function to cardiovascular risk factors in the Framingham Heart Study. Circulation (2008) 4.69
Effect of exercise training on endothelium-derived nitric oxide function in humans. J Physiol (2004) 3.48
The relationship between shear stress and flow-mediated dilatation: implications for the assessment of endothelial function. J Physiol (2005) 3.09
(-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans. Proc Natl Acad Sci U S A (2006) 3.03
Adipose macrophage infiltration is associated with insulin resistance and vascular endothelial dysfunction in obese subjects. Arterioscler Thromb Vasc Biol (2008) 2.82
Serum myeloperoxidase levels independently predict endothelial dysfunction in humans. Circulation (2004) 2.79
Aging and vascular endothelial function in humans. Clin Sci (Lond) (2011) 2.53
Circadian rhythms and metabolic syndrome: from experimental genetics to human disease. Circ Res (2010) 2.49
Hot flashes and subclinical cardiovascular disease: findings from the Study of Women's Health Across the Nation Heart Study. Circulation (2008) 2.33
25-Hydroxyvitamin D deficiency is associated with inflammation-linked vascular endothelial dysfunction in middle-aged and older adults. Hypertension (2010) 2.33
Regular aerobic exercise protects against impaired fasting plasma glucose-associated vascular endothelial dysfunction with aging. Clin Sci (Lond) (2013) 2.22
Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications. Rev Endocr Metab Disord (2010) 2.19
Physical inactivity rapidly induces insulin resistance and microvascular dysfunction in healthy volunteers. Arterioscler Thromb Vasc Biol (2007) 2.07
Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet. Circ Res (2005) 2.06
eNOS, metabolic syndrome and cardiovascular disease. Trends Endocrinol Metab (2009) 2.04
Relation of brachial and digital measures of vascular function in the community: the Framingham heart study. Hypertension (2011) 1.90
Aging is associated with greater nuclear NF kappa B, reduced I kappa B alpha, and increased expression of proinflammatory cytokines in vascular endothelial cells of healthy humans. Aging Cell (2008) 1.89
Measuring FMD in the brachial artery: how important is QRS gating? J Appl Physiol (1985) (2010) 1.75
Metabolic syndrome, insulin resistance, and brachial artery vasodilator function in Framingham Offspring participants without clinical evidence of cardiovascular disease. Am J Cardiol (2008) 1.74
Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study. Hum Mol Genet (2006) 1.74
Assessment of endothelial function using digital pulse amplitude tonometry. Trends Cardiovasc Med (2009) 1.69
Association of abacavir and impaired endothelial function in treated and suppressed HIV-infected patients. AIDS (2009) 1.67
Protecting against vascular disease in brain. Am J Physiol Heart Circ Physiol (2011) 1.66
Pre-eclampsia is associated with sleep-disordered breathing and endothelial dysfunction. Eur Respir J (2006) 1.65
AT1 receptors prevent salt-induced vascular dysfunction in isolated middle cerebral arteries of 2 kidney-1 clip hypertensive rats. Am J Hypertens (2013) 1.65
Genetic deletion of p66(Shc) adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress. Proc Natl Acad Sci U S A (2007) 1.63
Flow-mediated dilatation in the superficial femoral artery is nitric oxide mediated in humans. J Physiol (2007) 1.61
Low-renin hypertension with relative aldosterone excess is associated with impaired NO-mediated vasodilation. Hypertension (2005) 1.60
Green tea catechins and cardiovascular health: an update. Curr Med Chem (2008) 1.58
Reduced adipose tissue inflammation represents an intermediate cardiometabolic phenotype in obesity. J Am Coll Cardiol (2011) 1.57
Endothelial dysfunction: the early predictor of atherosclerosis. Cardiovasc J Afr (2012) 1.55
Endothelial dysfunction: associations with exposure to ambient fine particles in diabetic individuals. Environ Health Perspect (2008) 1.53
Suppression of the JNK pathway by induction of a metabolic stress response prevents vascular injury and dysfunction. Circulation (2008) 1.50
B6D2F1 Mice are a suitable model of oxidative stress-mediated impaired endothelium-dependent dilation with aging. J Gerontol A Biol Sci Med Sci (2009) 1.49
The vascular endothelium and human diseases. Int J Biol Sci (2013) 1.49
Insulin status and vascular responses to weight loss in obesity. J Am Coll Cardiol (2013) 1.47
Exercise for obese youth: refocusing attention from weight loss to health gains. Exerc Sport Sci Rev (2015) 1.40
Vascular endothelial function and hypertension: insights and directions. Curr Hypertens Rep (2010) 1.34
Update on nitric oxide-dependent vasodilation in human subjects. Methods Enzymol (2005) 1.34
Impact of age, sex, and exercise on brachial artery flow-mediated dilatation. Am J Physiol Heart Circ Physiol (2009) 1.32
Acute EGCG supplementation reverses endothelial dysfunction in patients with coronary artery disease. J Am Coll Nutr (2007) 1.30
Exercise rehabilitation in peripheral artery disease: functional impact and mechanisms of benefits. Circulation (2011) 1.27
Mitochondria and endothelial function. Circ Res (2013) 1.27
Endothelial dysfunction in chronic inflammatory diseases. Int J Mol Sci (2014) 1.26
Vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate-nitrite-nitric oxide pathway. Br J Clin Pharmacol (2013) 1.26
Allopurinol reduces B-type natriuretic peptide concentrations and haemoglobin but does not alter exercise capacity in chronic heart failure. Heart (2005) 1.26
Regulation of endothelial function by mitochondrial reactive oxygen species. Antioxid Redox Signal (2011) 1.25
Endothelial function as a functional expression of cardiovascular risk factors. Biomark Med (2010) 1.25
Effects of systemic inflammation on endothelium-dependent vasodilation. Trends Cardiovasc Med (2006) 1.24
Resistin: functional roles and therapeutic considerations for cardiovascular disease. Br J Pharmacol (2012) 1.22
Protein expression in vascular endothelial cells obtained from human peripheral arteries and veins. J Vasc Res (2009) 1.22
The endothelium and its role in regulating vascular tone. Open Cardiovasc Med J (2010) 1.21
Plasma nitrite response and arterial reactivity differentiate vascular health and performance. Nitric Oxide (2009) 1.20
Acute exposure to low glucose rapidly induces endothelial dysfunction and mitochondrial oxidative stress: role for AMP kinase. Arterioscler Thromb Vasc Biol (2011) 1.20
Diastolic dysfunction in diabetes and the metabolic syndrome: promising potential for diagnosis and prognosis. Diabetologia (2010) 1.18
Oxidative stress-related biomarkers in essential hypertension and ischemia-reperfusion myocardial damage. Dis Markers (2013) 1.16
Type II diabetes mellitus and cardiovascular risk factors: Current therapeutic approaches. Exp Clin Cardiol (2007) 1.15
Soluble TWEAK plasma levels as a novel biomarker of endothelial function in patients with chronic kidney disease. Clin J Am Soc Nephrol (2009) 1.13
Translational evidence that impaired autophagy contributes to arterial ageing. J Physiol (2012) 1.12
Effects of cranberry juice consumption on vascular function in patients with coronary artery disease. Am J Clin Nutr (2011) 1.11
Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice. Aging Cell (2013) 1.11
Normalization of flow-mediated dilation to shear stress area under the curve eliminates the impact of variable hyperemic stimulus. Cardiovasc Ultrasound (2008) 1.11
Evaluation of cuff-induced ischemia in the lower extremity by magnetic resonance oximetry. J Am Coll Cardiol (2010) 1.10
Peroxisome proliferator-activated receptor-gamma agonists and diabetes: current evidence and future perspectives. Vasc Health Risk Manag (2008) 1.10
Exposure to ambient concentrations of particulate air pollution does not influence vascular function or inflammatory pathways in young healthy individuals. Part Fibre Toxicol (2008) 1.10
Inorganic nitrate ingestion improves vascular compliance but does not alter flow-mediated dilatation in healthy volunteers. Nitric Oxide (2012) 1.10
Grapes and cardiovascular disease. J Nutr (2009) 1.09
Tea consumption enhances endothelial-dependent vasodilation; a meta-analysis. PLoS One (2011) 1.07
Vascular endothelial estrogen receptor alpha is modulated by estrogen status and related to endothelial function and endothelial nitric oxide synthase in healthy women. J Clin Endocrinol Metab (2009) 1.07
Cellular and molecular biology of aging endothelial cells. J Mol Cell Cardiol (2015) 1.07
Are vasomotor symptoms associated with alterations in hemostatic and inflammatory markers? Findings from the Study of Women's Health Across the Nation. Menopause (2011) 1.07
Relation of season and temperature to endothelium-dependent flow-mediated vasodilation in subjects without clinical evidence of cardiovascular disease (from the Framingham Heart Study). Am J Cardiol (2007) 1.07
Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries. Am J Physiol Heart Circ Physiol (2010) 1.06
Chlorine gas exposure causes systemic endothelial dysfunction by inhibiting endothelial nitric oxide synthase-dependent signaling. Am J Respir Cell Mol Biol (2010) 1.06
Role of genetic polymorphisms of ion channels in the pathophysiology of coronary microvascular dysfunction and ischemic heart disease. Basic Res Cardiol (2013) 1.05
Atorvastatin restores endothelial function in normocholesterolemic smokers independent of changes in low-density lipoprotein. Circ Res (2004) 1.05
Modest visceral fat gain causes endothelial dysfunction in healthy humans. J Am Coll Cardiol (2010) 1.04
The hyperaemic response to passive leg movement is dependent on nitric oxide: a new tool to evaluate endothelial nitric oxide function. J Physiol (2012) 1.03
MicroRNAs in atherosclerosis and lipoprotein metabolism. Curr Opin Endocrinol Diabetes Obes (2010) 1.03
Influence of aerobic training on cardiovascular and metabolic parameters in ederly hypertensive women. Int J Prev Med (2012) 1.03
Coenzyme Q10 improves endothelial dysfunction in statin-treated type 2 diabetic patients. Diabetes Care (2009) 1.02
Role of PET in the evaluation and understanding of coronary physiology. J Nucl Cardiol (2007) 1.02
Postprandial dysmetabolism and cardiovascular disease in type 2 diabetes. Postgrad Med J (2005) 1.01
Nitric oxide synthase expression and functional response to nitric oxide are both important modulators of circulating angiogenic cell response to angiogenic stimuli. Arterioscler Thromb Vasc Biol (2010) 1.01
Acute and chronic angiotensin-(1-7) restores vasodilation and reduces oxidative stress in mesenteric arteries of salt-fed rats. Am J Physiol Heart Circ Physiol (2011) 1.01
Low dietary sodium intake is associated with enhanced vascular endothelial function in middle-aged and older adults with elevated systolic blood pressure. Ther Adv Cardiovasc Dis (2009) 1.00
HDL and endothelial protection. Br J Pharmacol (2013) 0.99
Impaired endothelial function in preadolescent children with type 1 diabetes. Diabetes Care (2011) 0.99
Acute impact of retrograde shear rate on brachial and superficial femoral artery flow-mediated dilation in humans. Physiol Rep (2014) 0.98
miRNAs: roles and clinical applications in vascular disease. Expert Rev Mol Diagn (2011) 0.98
The effect of L-arginine and creatine on vascular function and homocysteine metabolism. Vasc Med (2009) 0.98
One Minute of Marijuana Secondhand Smoke Exposure Substantially Impairs Vascular Endothelial Function. J Am Heart Assoc (2016) 0.98
Short-term physical inactivity impairs vascular function. J Surg Res (2014) 0.97
Noninvasive assessment of preclinical atherosclerosis. Vasc Health Risk Manag (2006) 0.97
Impaired relaxation of cerebral arteries in the absence of elevated salt intake in normotensive congenic rats carrying the Dahl salt-sensitive renin gene. Am J Physiol Heart Circ Physiol (2010) 0.96
Late cardiovascular consequences of gestational diabetes mellitus. Semin Reprod Med (2009) 0.96
The autophagy enhancer spermidine reverses arterial aging. Mech Ageing Dev (2013) 0.95
Nitric oxide synthase-dependent vasodilation of human subcutaneous arterioles correlates with noninvasive measurements of endothelial function. Am J Hypertens (2012) 0.95
Arterial stiffness and cardiovascular events: the Framingham Heart Study. Circulation (2010) 9.09
Changes in arterial stiffness and wave reflection with advancing age in healthy men and women: the Framingham Heart Study. Hypertension (2004) 8.27
Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study. Arterioscler Thromb Vasc Biol (2003) 7.47
Role of oxidative modifications in atherosclerosis. Physiol Rev (2004) 6.73
Aortic stiffness, blood pressure progression, and incident hypertension. JAMA (2012) 6.01
Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study. Circulation (2007) 5.10
Clinical correlates and heritability of flow-mediated dilation in the community: the Framingham Heart Study. Circulation (2004) 4.73
Cross-sectional relations of digital vascular function to cardiovascular risk factors in the Framingham Heart Study. Circulation (2008) 4.69
Local shear stress and brachial artery flow-mediated dilation: the Framingham Heart Study. Hypertension (2004) 4.56
Sfrp5 is an anti-inflammatory adipokine that modulates metabolic dysfunction in obesity. Science (2010) 4.15
Predictive value of reactive hyperemia for cardiovascular events in patients with peripheral arterial disease undergoing vascular surgery. Arterioscler Thromb Vasc Biol (2007) 4.13
Predictive value of noninvasively determined endothelial dysfunction for long-term cardiovascular events in patients with peripheral vascular disease. J Am Coll Cardiol (2003) 3.87
Endothelial function in HIV-infected persons. Clin Infect Dis (2006) 3.80
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation (2011) 3.68
Risk stratification for postoperative cardiovascular events via noninvasive assessment of endothelial function: a prospective study. Circulation (2002) 3.67
Endothelial function: a barometer for cardiovascular risk? Circulation (2002) 3.31
Contribution of clinical correlates and 13 C-reactive protein gene polymorphisms to interindividual variability in serum C-reactive protein level. Circulation (2006) 3.15
Regulation of ROS signal transduction by NADPH oxidase 4 localization. J Cell Biol (2008) 3.13
Adipose macrophage infiltration is associated with insulin resistance and vascular endothelial dysfunction in obese subjects. Arterioscler Thromb Vasc Biol (2008) 2.82
Serum myeloperoxidase levels independently predict endothelial dysfunction in humans. Circulation (2004) 2.79
Systemic inflammation and COPD: the Framingham Heart Study. Chest (2007) 2.74
Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype. J Biol Chem (2009) 2.69
The assessment of endothelial function: from research into clinical practice. Circulation (2012) 2.68
Cross-sectional relations of peripheral microvascular function, cardiovascular disease risk factors, and aortic stiffness: the Framingham Heart Study. Circulation (2005) 2.49
Cross-sectional correlates of increased aortic stiffness in the community: the Framingham Heart Study. Circulation (2007) 2.42
Reactive oxygen species in cardiovascular disease. Free Radic Biol Med (2011) 2.29
Central role of mitochondrial aldehyde dehydrogenase and reactive oxygen species in nitroglycerin tolerance and cross-tolerance. J Clin Invest (2004) 2.22
Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications. Rev Endocr Metab Disord (2010) 2.19
Association of nitrotyrosine levels with cardiovascular disease and modulation by statin therapy. JAMA (2003) 2.16
Relations of inflammatory biomarkers and common genetic variants with arterial stiffness and wave reflection. Hypertension (2008) 2.14
Kynurenine is an endothelium-derived relaxing factor produced during inflammation. Nat Med (2010) 2.12
Physical inactivity rapidly induces insulin resistance and microvascular dysfunction in healthy volunteers. Arterioscler Thromb Vasc Biol (2007) 2.07
Hemodynamic correlates of blood pressure across the adult age spectrum: noninvasive evaluation in the Framingham Heart Study. Circulation (2010) 2.07
Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels. Hum Mol Genet (2010) 2.05
Vitamin K and vitamin D status: associations with inflammatory markers in the Framingham Offspring Study. Am J Epidemiol (2007) 2.02
Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway. J Biol Chem (2001) 1.99
Biomarkers of the osteoprotegerin pathway: clinical correlates, subclinical disease, incident cardiovascular disease, and mortality. Arterioscler Thromb Vasc Biol (2010) 1.95
Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus. Circulation (2011) 1.95
Relation of brachial and digital measures of vascular function in the community: the Framingham heart study. Hypertension (2011) 1.90
Genome-wide association with select biomarker traits in the Framingham Heart Study. BMC Med Genet (2007) 1.90
AMPK inhibits fatty acid-induced increases in NF-kappaB transactivation in cultured human umbilical vein endothelial cells. Biochem Biophys Res Commun (2004) 1.89
Protein kinase C-β contributes to impaired endothelial insulin signaling in humans with diabetes mellitus. Circulation (2012) 1.88
Testing endothelial vasomotor function: nitric oxide, a multipotent molecule. Circulation (2003) 1.85
Brachial artery vasodilator function and systemic inflammation in the Framingham Offspring Study. Circulation (2004) 1.84
Cross-sectional relations of multiple biomarkers from distinct biological pathways to brachial artery endothelial function. Circulation (2006) 1.78
CCL2 polymorphisms are associated with serum monocyte chemoattractant protein-1 levels and myocardial infarction in the Framingham Heart Study. Circulation (2005) 1.76
Metabolic syndrome, insulin resistance, and brachial artery vasodilator function in Framingham Offspring participants without clinical evidence of cardiovascular disease. Am J Cardiol (2008) 1.74
Cytokine-stimulated GTP cyclohydrolase I expression in endothelial cells requires coordinated activation of nuclear factor-kappaB and Stat1/Stat3. Circ Res (2004) 1.69
Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice. Circulation (2005) 1.69
Periodontal disease is associated with brachial artery endothelial dysfunction and systemic inflammation. Arterioscler Thromb Vasc Biol (2003) 1.69
NADPH oxidase 4 promotes endothelial angiogenesis through endothelial nitric oxide synthase activation. Circulation (2011) 1.68
Heritability and a genome-wide linkage scan for arterial stiffness, wave reflection, and mean arterial pressure: the Framingham Heart Study. Circulation (2005) 1.68
Shouldering the risk factor burden: infection, atherosclerosis, and the vascular endothelium. Circulation (2002) 1.65
Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. BMC Med Genet (2007) 1.65
Inducible Toll-like receptor and NF-kappaB regulatory pathway expression in human adipose tissue. Obesity (Silver Spring) (2008) 1.63
Relations of arterial stiffness and endothelial function to brain aging in the community. Neurology (2013) 1.60
Association of oxidative stress, insulin resistance, and diabetes risk phenotypes: the Framingham Offspring Study. Diabetes Care (2007) 1.60
Low-renin hypertension with relative aldosterone excess is associated with impaired NO-mediated vasodilation. Hypertension (2005) 1.60
Effect of combined treatment with alpha-Lipoic acid and acetyl-L-carnitine on vascular function and blood pressure in patients with coronary artery disease. J Clin Hypertens (Greenwich) (2007) 1.59
Genome scan of systemic biomarkers of vascular inflammation in the Framingham Heart Study: evidence for susceptibility loci on 1q. Atherosclerosis (2005) 1.59
Reduced adipose tissue inflammation represents an intermediate cardiometabolic phenotype in obesity. J Am Coll Cardiol (2011) 1.57
Circulating vascular growth factors and central hemodynamic load in the community. Hypertension (2012) 1.56
Regulation of angiogenesis by glycogen synthase kinase-3beta. J Biol Chem (2002) 1.54
Sickle cell anemia is associated with reduced nitric oxide bioactivity in peripheral conduit and resistance vessels. Am J Hematol (2003) 1.53
Suppression of the JNK pathway by induction of a metabolic stress response prevents vascular injury and dysfunction. Circulation (2008) 1.50
Obesity and cardiovascular disease. Circulation (2012) 1.49
Uncoupling protein 2 impacts endothelial phenotype via p53-mediated control of mitochondrial dynamics. Circ Res (2013) 1.48
Estradiol-mediated endothelial nitric oxide synthase association with heat shock protein 90 requires adenosine monophosphate-dependent protein kinase. Circulation (2005) 1.48
Inflammation, kidney function and albuminuria in the Framingham Offspring cohort. Nephrol Dial Transplant (2010) 1.46
Clinical correlates, heritability, and genetic linkage of circulating CD40 ligand in the Framingham Offspring Study. Am Heart J (2008) 1.45
Effect of medical and surgical weight loss on endothelial vasomotor function in obese patients. Am J Cardiol (2005) 1.44
Relation of novel echocardiographic measures to invasive hemodynamic assessment in scleroderma-associated pulmonary arterial hypertension. Arthritis Care Res (Hoboken) (2014) 1.43
Arterial stiffness in mild-to-moderate CKD. J Am Soc Nephrol (2009) 1.41
Proof That Lower Is Better--LDL Cholesterol and IMPROVE-IT. N Engl J Med (2015) 1.41
Altered mitochondrial membrane potential, mass, and morphology in the mononuclear cells of humans with type 2 diabetes. Transl Res (2010) 1.40
Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4. Free Radic Biol Med (2005) 1.36