Published in J Bacteriol on October 01, 2003
Genes and molecules of lactobacilli supporting probiotic action. Microbiol Mol Biol Rev (2008) 3.12
Predicted functions and linkage specificities of the products of the Streptococcus pneumoniae capsular biosynthetic loci. J Bacteriol (2007) 2.67
A new pneumococcal serotype, 11E, has a variably inactivated wcjE gene. J Infect Dis (2010) 2.23
Catabolite control protein A (CcpA) contributes to virulence and regulation of sugar metabolism in Streptococcus pneumoniae. J Bacteriol (2005) 2.09
Attachment of capsular polysaccharide to the cell wall of Streptococcus pneumoniae type 2 is required for invasive disease. Proc Natl Acad Sci U S A (2006) 1.50
Pneumococcal Capsules and Their Types: Past, Present, and Future. Clin Microbiol Rev (2015) 1.45
Structural basis for the regulation mechanism of the tyrosine kinase CapB from Staphylococcus aureus. PLoS Biol (2008) 1.38
Bacterial tyrosine kinases: evolution, biological function and structural insights. Philos Trans R Soc Lond B Biol Sci (2012) 1.26
Roles of the sortases of Streptococcus pneumoniae in assembly of the RlrA pilus. J Bacteriol (2008) 1.25
functional analysis of conserved gene products involved in assembly of Escherichia coli capsules and exopolysaccharides: evidence for molecular recognition between Wza and Wzc for colanic acid biosynthesis. J Bacteriol (2005) 1.23
Lysogeny of Streptococcus pneumoniae with MM1 phage: improved adherence and other phenotypic changes. Infect Immun (2006) 1.21
Control of EpsE, the phosphoglycosyltransferase initiating exopolysaccharide synthesis in Streptococcus thermophilus, by EpsD tyrosine kinase. J Bacteriol (2006) 1.18
Capsule type of Streptococcus pneumoniae determines growth phenotype. PLoS Pathog (2012) 1.17
Phylogenetic distribution and membrane topology of the LytR-CpsA-Psr protein family. BMC Genomics (2008) 1.15
Tyrosine phosphorylation of the UDP-glucose dehydrogenase of Escherichia coli is at the crossroads of colanic acid synthesis and polymyxin resistance. PLoS One (2008) 1.13
CpsE from type 2 Streptococcus pneumoniae catalyzes the reversible addition of glucose-1-phosphate to a polyprenyl phosphate acceptor, initiating type 2 capsule repeat unit formation. J Bacteriol (2005) 1.08
Sialylation of group B streptococcal capsular polysaccharide is mediated by cpsK and is required for optimal capsule polymerization and expression. J Bacteriol (2005) 1.06
Streptococcus iniae capsule impairs phagocytic clearance and contributes to virulence in fish. J Bacteriol (2006) 1.00
Functional analysis of the CpsA protein of Streptococcus agalactiae. J Bacteriol (2012) 0.97
The core promoter of the capsule operon of Streptococcus pneumoniae is necessary for colonization and invasive disease. Infect Immun (2013) 0.96
Initiation and synthesis of the Streptococcus pneumoniae type 3 capsule on a phosphatidylglycerol membrane anchor. J Bacteriol (2005) 0.95
The capsular polysaccharide of Staphylococcus aureus is attached to peptidoglycan by the LytR-CpsA-Psr (LCP) family of enzymes. J Biol Chem (2014) 0.95
Functional analysis of Burkholderia cepacia genes bceD and bceF, encoding a phosphotyrosine phosphatase and a tyrosine autokinase, respectively: role in exopolysaccharide biosynthesis and biofilm formation. Appl Environ Microbiol (2006) 0.95
Membrane topology and DNA-binding ability of the Streptococcal CpsA protein. J Bacteriol (2010) 0.95
Crystal structures of Wzb of Escherichia coli and CpsB of Streptococcus pneumoniae, representatives of two families of tyrosine phosphatases that regulate capsule assembly. J Mol Biol (2009) 0.94
Characterization and site-directed mutagenesis of Wzb, an O-phosphatase from Lactobacillus rhamnosus. BMC Biochem (2008) 0.91
Mycobacterium tuberculosis supports protein tyrosine phosphorylation. Proc Natl Acad Sci U S A (2014) 0.89
Biochemical activities of Streptococcus pneumoniae serotype 2 capsular glycosyltransferases and significance of suppressor mutations affecting the initiating glycosyltransferase Cps2E. J Bacteriol (2013) 0.87
LytR-CpsA-Psr enzymes as determinants of Bacillus anthracis secondary cell wall polysaccharide assembly. J Bacteriol (2014) 0.86
Mutations in pneumococcal cpsE generated via in vitro serial passaging reveal a potential mechanism of reduced encapsulation utilized by a conjunctival isolate. J Bacteriol (2015) 0.85
Streptococcus pneumoniae phosphotyrosine phosphatase CpsB and alterations in capsule production resulting from changes in oxygen availability. J Bacteriol (2014) 0.84
Chemical inhibition of bacterial protein tyrosine phosphatase suppresses capsule production. PLoS One (2012) 0.82
Protein-tyrosine phosphorylation in Bacillus subtilis: a 10-year retrospective. Front Microbiol (2015) 0.82
The role of bacterial protein tyrosine phosphatases in the regulation of the biosynthesis of secreted polysaccharides. Antioxid Redox Signal (2014) 0.81
Sequence elements upstream of the core promoter are necessary for full transcription of the capsule gene operon in Streptococcus pneumoniae strain D39. Infect Immun (2015) 0.81
Complete Genome Sequence of Thermus aquaticus Y51MC23. PLoS One (2015) 0.78
Heterologous expression of the pneumococcal serotype 14 polysaccharide in Lactococcus lactis requires lactococcal epsABC regulatory genes. Appl Environ Microbiol (2007) 0.78
A sweet new role for LCP enzymes in protein glycosylation. Mol Microbiol (2014) 0.77
Discovery of a new genetic variant of methionine aminopeptidase from Streptococci with possible post-translational modifications: biochemical and structural characterization. PLoS One (2013) 0.77
Modification of the CpsA protein reveals a role in alteration of the Streptococcus agalactiae cell envelope. Infect Immun (2015) 0.77
A genomic approach to understand interactions between Streptococcus pneumoniae and its bacteriophages. BMC Genomics (2015) 0.76
Assembling of the Mycobacterium tuberculosis Cell Wall Core. J Biol Chem (2016) 0.76
The sensor histidine kinase RgfC affects group B streptococcal virulence factor expression independent of its response regulator RgfA. Infect Immun (2015) 0.76
Autophosphorylation of the Bacterial Tyrosine-Kinase CpsD Connects Capsule Synthesis with the Cell Cycle in Streptococcus pneumoniae. PLoS Genet (2015) 0.76
Recombinant expression of Streptococcus pneumoniae capsular polysaccharides in Escherichia coli. Open Biol (2016) 0.75
A tyrosine phosphorylation switch controls the interaction between the transmembrane modulator protein Wzd and the tyrosine kinase Wze of Lactobacillus rhamnosus. BMC Microbiol (2015) 0.75
Topology of Streptococcus pneumoniae CpsC, a polysaccharide copolymerase and bacterial protein tyrosine kinase adaptor protein. J Bacteriol (2014) 0.75
Method for detection of specific RNAs in agarose gels by transfer to diazobenzyloxymethyl-paper and hybridization with DNA probes. Proc Natl Acad Sci U S A (1977) 40.24
STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES : INDUCTION OF TRANSFORMATION BY A DESOXYRIBONUCLEIC ACID FRACTION ISOLATED FROM PNEUMOCOCCUS TYPE III. J Exp Med (1944) 24.08
Complete genome sequence of a virulent isolate of Streptococcus pneumoniae. Science (2001) 21.99
Surface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelope. Microbiol Mol Biol Rev (1999) 7.76
Six newly recognized types of Streptococcus pneumoniae. J Clin Microbiol (1995) 7.32
Antiphosphocholine antibodies found in normal mouse serum are protective against intravenous infection with type 3 streptococcus pneumoniae. J Exp Med (1981) 6.45
THE PROTECTIVE ACTION OF A SPECIFIC ENZYME AGAINST TYPE III PNEUMOCOCCUS INFECTION IN MICE. J Exp Med (1931) 5.05
Destruction of low efficiency markers is a slow process occurring at a heteroduplex stage of transformation. Mol Gen Genet (1974) 4.93
Association of intrastrain phase variation in quantity of capsular polysaccharide and teichoic acid with the virulence of Streptococcus pneumoniae. J Infect Dis (1998) 4.12
Structure, assembly and regulation of expression of capsules in Escherichia coli. Mol Microbiol (1999) 4.05
Strong association between capsular type and virulence for mice among human isolates of Streptococcus pneumoniae. Infect Immun (1992) 3.80
Purification and characterization of Staphylococcus aureus type 8 capsular polysaccharide. Infect Immun (1984) 3.14
Novel surface attachment mechanism of the Streptococcus pneumoniae protein PspA. J Bacteriol (1994) 3.12
The Significance of Pneumococcal Types. J Hyg (Lond) (1928) 3.00
Sequencing and analysis of the Bacillus subtilis lytRABC divergon: a regulatory unit encompassing the structural genes of the N-acetylmuramoyl-L-alanine amidase and its modifier. J Gen Microbiol (1992) 2.93
Lipid on capsular polysaccharides of gram-negative bacteria. J Biol Chem (1981) 2.91
Transformation of encapsulated Streptococcus pneumoniae. J Bacteriol (1986) 2.82
Truncated forms of PspA that are secreted from Streptococcus pneumoniae and their use in functional studies and cloning of the pspA gene. J Bacteriol (1992) 2.80
Requirement for capsule in colonization by Streptococcus pneumoniae. Infect Immun (2001) 2.55
The inhibition of surface phagocytosis by the capsular slime layer of pneumococcus type III. J Exp Med (1949) 2.48
Characterization of the cassette containing genes for type 3 capsular polysaccharide biosynthesis in Streptococcus pneumoniae. J Exp Med (1995) 2.36
Tyrosine phosphorylation of CpsD negatively regulates capsular polysaccharide biosynthesis in streptococcus pneumoniae. Mol Microbiol (2000) 2.34
Functional analysis in type Ia group B Streptococcus of a cluster of genes involved in extracellular polysaccharide production by diverse species of streptococci. J Biol Chem (2001) 2.30
Nucleotide sequence analysis of genes essential for capsular polysaccharide biosynthesis in Streptococcus pneumoniae type 19F. Infect Immun (1994) 2.24
Protection of mice from infection with Streptococcus pneumoniae by anti-phosphocholine antibody. Infect Immun (1982) 2.19
The type 2 capsule locus of Streptococcus pneumoniae. J Bacteriol (1999) 2.12
The role of complement in the host's defense against Streptococcus pneumoniae. Rev Infect Dis (1981) 2.06
Gene products required for surface expression of the capsular form of the group 1 K antigen in Escherichia coli (O9a:K30). Mol Microbiol (1999) 2.02
Phosphorylation of Wzc, a tyrosine autokinase, is essential for assembly of group 1 capsular polysaccharides in Escherichia coli. J Biol Chem (2000) 1.96
The Streptococcus pneumoniae beta-galactosidase is a surface protein. J Bacteriol (2000) 1.89
Covalent linkage between the capsular polysaccharide and the cell wall peptidoglycan of Streptococcus pneumoniae revealed by immunochemical methods. Microb Pathog (1990) 1.86
Genetic and molecular characterization of capsular polysaccharide biosynthesis in Streptococcus pneumoniae type 3. Mol Microbiol (1994) 1.77
Protein tyrosine kinases in bacterial pathogens are associated with virulence and production of exopolysaccharide. EMBO J (1999) 1.72
Sequence and transcriptional analysis of a DNA region involved in the production of capsular polysaccharide in Streptococcus pneumoniae type 3. Gene (1995) 1.70
Changes in availability of oxygen accentuate differences in capsular polysaccharide expression by phenotypic variants and clinical isolates of Streptococcus pneumoniae. Infect Immun (2001) 1.69
Cells of Escherichia coli contain a protein-tyrosine kinase, Wzc, and a phosphotyrosine-protein phosphatase, Wzb. J Bacteriol (1999) 1.64
Relationship between exopolysaccharide production and protein-tyrosine phosphorylation in gram-negative bacteria. J Mol Biol (2000) 1.55
Genetic alteration of capsule type but not PspA type affects accessibility of surface-bound complement and surface antigens of Streptococcus pneumoniae. Infect Immun (2003) 1.54
Group B, type III streptococcal cell wall: composition and structural aspects revealed through endo-N-acetylmuramidase-catalyzed hydrolysis. Infect Immun (1982) 1.52
Streptococcus pneumoniae capsule biosynthesis protein CpsB is a novel manganese-dependent phosphotyrosine-protein phosphatase. J Bacteriol (2002) 1.50
Isolation, characterization, and nucleotide sequence of IS1202, an insertion sequence of Streptococcus pneumoniae. J Bacteriol (1994) 1.48
Impact of phosphorylation of specific residues in the tyrosine autokinase, Wzc, on its activity in assembly of group 1 capsules in Escherichia coli. J Bacteriol (2002) 1.47
Capsule biosynthesis and basic metabolism in Streptococcus pneumoniae are linked through the cellular phosphoglucomutase. J Bacteriol (2000) 1.42
Characterization of binding of human lactoferrin to pneumococcal surface protein A. Infect Immun (2001) 1.40
Mouse antibody to phosphocholine can protect mice from infection with mouse-virulent human isolates of Streptococcus pneumoniae. Infect Immun (1992) 1.35
Evaluation of Wzz/MPA1/MPA2 proteins based on the presence of coiled-coil regions. Microbiology (2000) 1.35
Mutational analysis of the carboxy-terminal (YGX)4 repeat domain of CpsD, an autophosphorylating tyrosine kinase required for capsule biosynthesis in Streptococcus pneumoniae. J Bacteriol (2003) 1.33
Decay of ompA mRNA and processing of 9S RNA are immediately affected by shifts in growth rate, but in opposite manners. J Bacteriol (1992) 1.30
Biosynthesis of cell wall peptidoglycan and polysaccharide antigens by protoplasts of type III group B Streptococcus. J Bacteriol (1983) 1.28
Essential role for cellular phosphoglucomutase in virulence of type 3 Streptococcus pneumoniae. Infect Immun (2001) 1.27
Biosynthetic control of molecular weight in the polymerization of the octasaccharide subunits of succinoglycan, a symbiotically important exopolysaccharide of Rhizobium meliloti. Proc Natl Acad Sci U S A (1998) 1.26
CpsB is a modulator of capsule-associated tyrosine kinase activity in Streptococcus pneumoniae. J Biol Chem (2001) 1.26
Low-molecular-weight succinoglycan is predominantly produced by Rhizobium meliloti strains carrying a mutated ExoP protein characterized by a periplasmic N-terminal domain and a missing C-terminal domain. Mol Microbiol (1995) 1.24
Characterization of the linkage between the type III capsular polysaccharide and the bacterial cell wall of group B Streptococcus. J Biol Chem (2000) 1.21
Mechanism of type 3 capsular polysaccharide synthesis in Streptococcus pneumoniae. J Biol Chem (2000) 1.19
Interaction of gram-positive microorganisms with complement. Curr Top Microbiol Immunol (1985) 1.19
The molecular weight distribution of succinoglycan produced by Sinorhizobium meliloti is influenced by specific tyrosine phosphorylation and ATPase activity of the cytoplasmic domain of the ExoP protein. J Bacteriol (2001) 1.14
Characterization of a bacterial gene encoding an autophosphorylating protein tyrosine kinase. Gene (1997) 1.12
Isolation and characterization of type III group B streptococcal mutants defective in biosynthesis of the type-specific antigen. Infect Immun (1983) 1.08
Capsule genetics in Streptococcus pneumoniae and a possible role for transposition in the generation of the type 3 locus. Microb Drug Resist (1998) 1.06
Evidence for covalent attachment of phospholipid to the capsular polysaccharide of Haemophilus influenzae type b. J Bacteriol (1985) 1.05
Biosynthesis of type 3 capsular polysaccharide in Streptococcus pneumoniae. Enzymatic chain release by an abortive translocation process. J Biol Chem (2000) 1.03
Structural studies of the capsular polysaccharide from Streptococcus pneumoniae type 2, a reinvestigation. Carbohydr Res (1988) 1.00
Capsules and cassettes: genetic organization of the capsule locus of Streptococcus pneumoniae. Dev Biol Stand (1995) 0.88
Epidemiologic studies of group 9 pneumococci in terms of protein type and 9N versus 9V capsular type. J Infect Dis (1991) 0.78
Biochemical, genetic, and serological characterization of two capsule subtypes among Streptococcus pneumoniae Serotype 20 strains: discovery of a new pneumococcal serotype. J Biol Chem (2012) 1.90
Genetic alteration of capsule type but not PspA type affects accessibility of surface-bound complement and surface antigens of Streptococcus pneumoniae. Infect Immun (2003) 1.54
LambdaSa1 and LambdaSa2 prophage lysins of Streptococcus agalactiae. Appl Environ Microbiol (2007) 1.25
CpsE from type 2 Streptococcus pneumoniae catalyzes the reversible addition of glucose-1-phosphate to a polyprenyl phosphate acceptor, initiating type 2 capsule repeat unit formation. J Bacteriol (2005) 1.08
CcpA-dependent and -independent control of beta-galactosidase expression in Streptococcus pneumoniae occurs via regulation of an upstream phosphotransferase system-encoding operon. J Bacteriol (2007) 1.08
Control of capsular polysaccharide chain length by UDP-sugar substrate concentrations in Streptococcus pneumoniae. Mol Microbiol (2006) 1.08
A new model of pneumococcal lipoteichoic acid structure resolves biochemical, biosynthetic, and serologic inconsistencies of the current model. J Bacteriol (2008) 1.05
Streptococcus pneumoniae serotype 11D has a bispecific glycosyltransferase and expresses two different capsular polysaccharide repeating units. J Biol Chem (2013) 0.97
Initiation and synthesis of the Streptococcus pneumoniae type 3 capsule on a phosphatidylglycerol membrane anchor. J Bacteriol (2005) 0.95
Role of the carbohydrate binding site of the Streptococcus pneumoniae capsular polysaccharide type 3 synthase in the transition from oligosaccharide to polysaccharide synthesis. J Biol Chem (2006) 0.92
Biochemical activities of Streptococcus pneumoniae serotype 2 capsular glycosyltransferases and significance of suppressor mutations affecting the initiating glycosyltransferase Cps2E. J Bacteriol (2013) 0.87
Streptococcus pneumoniae phosphotyrosine phosphatase CpsB and alterations in capsule production resulting from changes in oxygen availability. J Bacteriol (2014) 0.84
A kinetic model for chain length modulation of Streptococcus pneumoniae cellubiuronan capsular polysaccharide by nucleotide sugar donor concentrations. J Biol Chem (2009) 0.84
Characterization of the lipid linkage region and chain length of the cellubiuronic acid capsule of Streptococcus pneumoniae. J Biol Chem (2009) 0.77