Published in J Clin Endocrinol Metab on October 01, 2003
Genetic regulation of pituitary gland development in human and mouse. Endocr Rev (2009) 2.02
Identification of HESX1 mutations in Kallmann syndrome. Fertil Steril (2013) 1.62
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Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein. Cell (2009) 2.69
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Semen analysis in adolescent cancer patients prior to bone marrow transplantation: when is it too late for fertility preservation? Pediatr Blood Cancer (2012) 2.04
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Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling. Blood (2007) 1.73
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Timing and completion of puberty in female mice depend on estrogen receptor alpha-signaling in kisspeptin neurons. Proc Natl Acad Sci U S A (2010) 1.62
Ubiquitin binding to A20 ZnF4 is required for modulation of NF-κB signaling. Mol Cell (2010) 1.41
Molecular basis of combined pituitary hormone deficiencies. Endocr Rev (2002) 1.38
Update of guidelines for the use of growth hormone in children: the Lawson Wilkins Pediatric Endocrinology Society Drug and Therapeutics Committee. J Pediatr (2003) 1.36
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Human type 3 iodothyronine selenodeiodinase is located in the plasma membrane and undergoes rapid internalization to endosomes. J Biol Chem (2002) 1.26
Impaired estrogen feedback and infertility in female mice with pituitary-specific deletion of estrogen receptor alpha (ESR1). Biol Reprod (2009) 1.21
Rescue of obesity-induced infertility in female mice due to a pituitary-specific knockout of the insulin receptor. Cell Metab (2010) 1.20
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Genetic overlap in Kallmann syndrome, combined pituitary hormone deficiency, and septo-optic dysplasia. J Clin Endocrinol Metab (2012) 1.18
Divergent roles of growth factors in the GnRH regulation of puberty in mice. J Clin Invest (2010) 1.13
Preparation of distinct ubiquitin chain reagents of high purity and yield. Structure (2011) 1.11
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An intact DNA-binding domain is not required for peroxisome proliferator-activated receptor gamma (PPARgamma) binding and activation on some PPAR response elements. J Biol Chem (2004) 1.06
Pubertal development and menarche. Ann N Y Acad Sci (2008) 1.06
Diencephalic syndrome: a cause of failure to thrive and a model of partial growth hormone resistance. Pediatrics (2005) 1.06
Generation and characterization of a complete null estrogen receptor alpha mouse using Cre/LoxP technology. Mol Cell Biochem (2008) 1.06
Disrupted kisspeptin signaling in GnRH neurons leads to hypogonadotrophic hypogonadism. Mol Endocrinol (2014) 1.05
Defects of prostate development and reproductive system in the estrogen receptor-alpha null male mice. Endocrinology (2008) 1.01
Kisspeptin increases GnRH mRNA expression and secretion in GnRH secreting neuronal cell lines. Mol Cell Endocrinol (2009) 1.01
Endocrinology of female puberty. Curr Opin Endocrinol Diabetes Obes (2009) 1.00
Community and family perspectives on addressing overweight in urban, African-American youth. J Gen Intern Med (2007) 1.00
A novel dominant negative mutation of OTX2 associated with combined pituitary hormone deficiency. J Clin Endocrinol Metab (2008) 0.99
Transcriptional co-activator p300 maintains basal hepatic gluconeogenesis. J Biol Chem (2012) 0.99
A novel technique for temporally regulated cell type-specific Cre expression and recombination in the pituitary gonadotroph. J Mol Endocrinol (2006) 0.99
Egr-1 binds the GnRH promoter to mediate the increase in gene expression by insulin. Mol Cell Endocrinol (2007) 0.98
Deletion of Otx2 in GnRH neurons results in a mouse model of hypogonadotropic hypogonadism. Mol Endocrinol (2011) 0.97
Obesity-induced infertility and hyperandrogenism are corrected by deletion of the insulin receptor in the ovarian theca cell. Diabetes (2013) 0.97
Estrogen regulation of gene expression in GnRH neurons. Mol Cell Endocrinol (2009) 0.96
Late adolescent linear growth pattern in pediatric-onset inflammatory bowel disease. J Pediatr Gastroenterol Nutr (2011) 0.95
Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling. Science (2013) 0.95
Imaging the structure of the human anxious brain: a review of findings from neuroscientific personality psychology. Rev Neurosci (2013) 0.94
Positive, but not negative feedback actions of estradiol in adult female mice require estrogen receptor α in kisspeptin neurons. Endocrinology (2014) 0.94
Low concentrations of metformin suppress glucose production in hepatocytes through AMP-activated protein kinase (AMPK). J Biol Chem (2014) 0.93
Promoter sequences targeting tissue-specific gene expression of hypothalamic and ovarian gonadotropin-releasing hormone in vivo. J Biol Chem (2001) 0.93
The molecular basis of hypopituitarism. Trends Endocrinol Metab (2009) 0.93
Insulin augments GnRH-stimulated LHbeta gene expression by Egr-1. Mol Cell Endocrinol (2006) 0.92
Assessing skeletal maturity by using blood spot insulin-like growth factor I (IGF-I) testing. Am J Orthod Dentofacial Orthop (2008) 0.92
In vivo identification of a 107-base pair promoter element mediating neuron-specific expression of mouse gonadotropin-releasing hormone. Mol Endocrinol (2006) 0.91
Targeted deletion of somatotroph insulin-like growth factor-I signaling in a cell-specific knockout mouse model. Mol Endocrinol (2010) 0.91
The role of the catechol-O-methyltransferase (COMT) gene in personality and related psychopathological disorders. CNS Neurol Disord Drug Targets (2012) 0.91
Sleep dysfunction in long term survivors of craniopharyngioma. J Neurooncol (2012) 0.90
Activation of basal gluconeogenesis by coactivator p300 maintains hepatic glycogen storage. Mol Endocrinol (2013) 0.89
Novel mutations associated with combined pituitary hormone deficiency. J Mol Endocrinol (2011) 0.89
Identification of a discrete promoter region of the human GnRH gene that is sufficient for directing neuron-specific expression: a role for POU homeodomain transcription factors. Mol Endocrinol (2002) 0.87
Three novel IGFALS gene mutations resulting in total ALS and severe circulating IGF-I/IGFBP-3 deficiency in children of different ethnic origins. Horm Res (2009) 0.87
The gonadotropin-releasing hormone cell-specific element is required for normal puberty and estrous cyclicity. J Neurosci (2011) 0.86
Isolated prolactin deficiency associated with serum autoantibodies against prolactin-secreting cells. J Clin Endocrinol Metab (2013) 0.85
Barriers to fertility preservation in male adolescents with cancer: it's time for a multidisciplinary approach that includes urologists. Urology (2012) 0.85
A novel OTX2 mutation in a patient with combined pituitary hormone deficiency, pituitary malformation, and an underdeveloped left optic nerve. Eur J Endocrinol (2012) 0.84
Differential effects of ABT-510 and a CD36-binding peptide derived from the type 1 repeats of thrombospondin-1 on fatty acid uptake, nitric oxide signaling, and caspase activation in vascular cells. Biochem Pharmacol (2007) 0.84
Relationship between blood-spot insulin-like growth factor 1 levels and hand-wrist assessment of skeletal maturity. Am J Orthod Dentofacial Orthop (2009) 0.84
Insulin-like growth factor 1 mediates negative feedback to somatotroph GH expression via POU1F1/CREB binding protein interactions. Mol Cell Biol (2012) 0.84
A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum. Endocr Relat Cancer (2011) 0.84
A deletion involving CD38 and BST1 results in a fusion transcript in a patient with autism and asthma. Autism Res (2014) 0.84
Comparison of detection of normal puberty in girls by a hormonal sleep test and a gonadotropin-releasing hormone agonist test. J Clin Endocrinol Metab (2013) 0.84
Genetic mechanisms mediating kisspeptin regulation of GnRH gene expression. J Neurosci (2012) 0.84
Long-term clinical outcomes following treatment of childhood craniopharyngioma. Pediatr Blood Cancer (2010) 0.83
Is treatment with 6-mercaptopurine for colitis associated with the development of colorectal cancer? Inflamm Bowel Dis (2013) 0.83
Discovery of selective and noncovalent diaminopyrimidine-based inhibitors of epidermal growth factor receptor containing the T790M resistance mutation. J Med Chem (2014) 0.82
Factor VIIa inhibitors: chemical optimization, preclinical pharmacokinetics, pharmacodynamics, and efficacy in an arterial baboon thrombosis model. Bioorg Med Chem Lett (2006) 0.82
Bisphosphonate treatment of pediatric bone disease. Pediatr Endocrinol Rev (2005) 0.81
Growth Hormone and Treatment Controversy; Long Term Safety of rGH. Curr Pediatr Rep (2013) 0.81
Both estrogen receptor α and β stimulate pituitary GH gene expression. Mol Endocrinol (2013) 0.80
Developmental and endocrine regulation of kisspeptin expression in mouse Leydig cells. Endocrinology (2015) 0.80
Novel 5-azaindole factor VIIa inhibitors. Bioorg Med Chem Lett (2006) 0.79
The role of CBP/p300 interactions and Pit-1 dimerization in the pathophysiological mechanism of combined pituitary hormone deficiency. J Clin Endocrinol Metab (2005) 0.79
CREB binding protein (CBP) activation is required for luteinizing hormone beta expression and normal fertility in mice. Mol Cell Biol (2012) 0.78
Variation in methods of predicting adult height for children with idiopathic short stature. Pediatrics (2010) 0.78
Assessment of adrenal suppression in children with asthma treated with inhaled corticosteroids: use of dehydroepiandrosterone sulfate as a screening test. Ann Allergy Asthma Immunol (2006) 0.78
Discovery of novel heterocyclic factor VIIa inhibitors. Bioorg Med Chem Lett (2006) 0.77
Comparison of detection of normal puberty in boys by a hormonal sleep test and a gonadotropin-releasing hormone agonist test. J Clin Endocrinol Metab (2012) 0.77
Guidelines for Growth Hormone and Insulin-Like Growth Factor-I Treatment in Children and Adolescents: Growth Hormone Deficiency, Idiopathic Short Stature, and Primary Insulin-Like Growth Factor-I Deficiency. Horm Res Paediatr (2016) 0.77
Isolated central hypothyroidism in young siblings as a manifestation of PROP1 deficiency: clinical impact of whole exome sequencing. Horm Res Paediatr (2013) 0.77
Factor VIIa inhibitors: gaining selectivity within the trypsin family. Bioorg Med Chem Lett (2006) 0.77
Other transcription factors and hypopituitarism. Rev Endocr Metab Disord (2002) 0.76
The GnRH neuron: molecular aspects of migration, gene expression and regulation. Prog Brain Res (2002) 0.76
A novel nonsense mutation in the Pit-1 gene: evidence for a gene dosage effect. J Clin Endocrinol Metab (2003) 0.76
Predictors of neoplastic disease in children with isolated pituitary stalk thickening. Pediatr Blood Cancer (2013) 0.76
Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study. J Med Chem (2015) 0.76
Fertility and sexual function: a gap in training in pediatric endocrinology. J Pediatr Endocrinol Metab (2017) 0.76
pH-triggered release of macromolecules from spray-dried polymethacrylate microparticles. Pharm Res (2003) 0.75
Vertical transmission of hypopituitarism: critical importance of appropriate interpretation of thyroid function tests and levothyroxine therapy during pregnancy. Thyroid (2013) 0.75
Detection of EPO gene doping in blood. Drug Test Anal (2012) 0.75
Does treatment of childhood congenital adrenal hyperplasia with prednisone adversely affect final height? Nat Clin Pract Endocrinol Metab (2007) 0.75
Deciphering the genetics of stature--another piece of the puzzle. J Clin Endocrinol Metab (2006) 0.75
Klinefelter syndrome: are we missing opportunities for early detection? Clin Pediatr (Phila) (2013) 0.75
The lack of relationship between serum content of MBL, sCD14, anti-PPD and anti-Hsp65 IgG and ingestion of Mycobacterium bovis BCG bacilli by phagocytes. Arch Immunol Ther Exp (Warsz) (2002) 0.75
Potential role of IGF-1 z score to predict permanent linear growth impairment in children with IBD. J Pediatr Gastroenterol Nutr (2014) 0.75
JAMA patient page. Short stature. JAMA (2014) 0.75