Published in Mol Cell Biol on April 16, 2012
The regulation of reproductive neuroendocrine function by insulin and insulin-like growth factor-1 (IGF-1). Front Neuroendocrinol (2014) 0.85
The Myb-p300-CREB axis modulates intestine homeostasis, radiosensitivity and tumorigenesis. Cell Death Dis (2013) 0.79
FOXO1 is regulated by insulin and IGF1 in pituitary gonadotropes. Mol Cell Endocrinol (2015) 0.77
Systematic Analysis of Protein Interaction Network Associated with Azoospermia. Int J Mol Sci (2016) 0.75
Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature (1993) 11.54
Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell (1989) 11.41
A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell (1996) 11.02
CBP/p300 in cell growth, transformation, and development. Genes Dev (2000) 10.76
Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature (1994) 9.37
Role of brain insulin receptor in control of body weight and reproduction. Science (2000) 8.14
Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP. Nature (1995) 7.11
CREB-binding protein and p300 in transcriptional regulation. J Biol Chem (2001) 4.67
Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1). Science (1996) 3.39
A longitudinal study of estrous cyclicity in aging C57BL/6J mice: I. Cycle frequency, length and vaginal cytology. Biol Reprod (1982) 3.28
Phosphorylation of CREB at Ser-133 induces complex formation with CREB-binding protein via a direct mechanism. Mol Cell Biol (1996) 2.84
Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein. Cell (2009) 2.69
A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo. Mol Cell Biol (2000) 2.33
Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression. EMBO J (2007) 2.07
Cell lines of the pituitary gonadotrope lineage derived by targeted oncogenesis in transgenic mice. Mol Endocrinol (1990) 2.05
Molecular biology of the pituitary gonadotropins. Endocr Rev (1990) 1.83
Cell-specific transcriptional regulation of follicle-stimulating hormone-beta by activin and gonadotropin-releasing hormone in the LbetaT2 pituitary gonadotrope cell model. Endocrinology (2001) 1.82
Individual CREB-target genes dictate usage of distinct cAMP-responsive coactivation mechanisms. EMBO J (2007) 1.67
MAP kinase-dependent transcriptional coactivation by Elk-1 and its cofactor CBP. Biochem Biophys Res Commun (1996) 1.65
Egr-1 is a downstream effector of GnRH and synergizes by direct interaction with Ptx1 and SF-1 to enhance luteinizing hormone beta gene transcription. Mol Cell Biol (1999) 1.65
Modulation of cytokine-induced HIV gene expression by competitive binding of transcription factors to the coactivator p300. EMBO J (1998) 1.56
Insulin regulation of hepatic gluconeogenesis through phosphorylation of CREB-binding protein. Nat Med (2004) 1.53
Steroidogenic factor 1 (SF1) is essential for pituitary gonadotrope function. Development (2001) 1.46
Steroid and pulsatile gonadotropin-releasing hormone (GnRH) regulation of luteinizing hormone and GnRH receptor in a novel gonadotrope cell line. Mol Endocrinol (1996) 1.44
Increased pancreatic beta-cell proliferation mediated by CREB binding protein gene activation. Mol Cell Biol (2006) 1.42
Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites. J Biol Chem (2003) 1.40
Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses. Mol Cell (2004) 1.38
Mechanisms for pulsatile regulation of the gonadotropin subunit genes by GNRH1. Biol Reprod (2006) 1.31
A pulsatile gonadotropin-releasing hormone stimulus is required to increase transcription of the gonadotropin subunit genes: evidence for differential regulation of transcription by pulse frequency in vivo. Endocrinology (1991) 1.29
The L beta T2 clonal gonadotrope: a model for single cell studies of endocrine cell secretion. Endocrinology (1996) 1.27
CREB binding protein recruitment to the transcription complex requires growth factor-dependent phosphorylation of its GF box. Mol Cell (2001) 1.22
Rescue of obesity-induced infertility in female mice due to a pituitary-specific knockout of the insulin receptor. Cell Metab (2010) 1.20
Insulin enhancement of luteinizing hormone and follicle-stimulating hormone release by cultured pituitary cells. Endocrinology (1981) 1.15
Sp1, steroidogenic factor 1 (SF-1), and early growth response protein 1 (egr-1) binding sites form a tripartite gonadotropin-releasing hormone response element in the rat luteinizing hormone-beta gene promoter: an integral role for SF-1. Mol Endocrinol (2000) 1.13
Gonadotropin-releasing hormone pulse frequency-dependent activation of extracellular signal-regulated kinase pathways in perifused LbetaT2 cells. Endocrinology (2005) 1.13
cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1). Biochem J (1998) 1.12
Early growth response protein 1 binds to the luteinizing hormone-beta promoter and mediates gonadotropin-releasing hormone-stimulated gene expression. Mol Endocrinol (1999) 1.11
Stimulation of luteinizing hormone beta gene promoter activity by the orphan nuclear receptor, steroidogenic factor-1. J Biol Chem (1996) 1.11
Suppression of pulsatile luteinizing hormone and testosterone secretion during short term food restriction in the adult male rhesus monkey (Macaca mulatta). Endocrinology (1991) 1.08
Divergent and composite gonadotropin-releasing hormone-responsive elements in the rat luteinizing hormone subunit genes. Mol Endocrinol (2000) 0.98
Expression and signal transduction pathways of gonadotropin-releasing hormone receptors. Recent Prog Horm Res (1995) 0.96
cAMP response element-binding protein-binding protein mediates thyrotropin-releasing hormone signaling on thyrotropin subunit genes. J Biol Chem (2000) 0.94
Luteinizing hormone beta promoter stimulation by adenylyl cyclase and cooperation with gonadotropin-releasing hormone 1 in transgenic mice and LBetaT2 Cells. Biol Reprod (2007) 0.93
Insulin augments GnRH-stimulated LHbeta gene expression by Egr-1. Mol Cell Endocrinol (2006) 0.92
Insulin enhances the transcription of luteinizing hormone-beta gene. Am J Obstet Gynecol (2004) 0.90
Gonadotropin-releasing hormone (GnRH) pulse pattern regulates GnRH receptor gene expression: augmentation by estradiol. Endocrinology (1995) 0.89
Small nuclear RING finger protein stimulates the rat luteinizing hormone-beta promoter by interacting with Sp1 and steroidogenic factor-1 and protects from androgen suppression. Mol Endocrinol (2004) 0.87
Insulin augments gonadotropin-releasing hormone induction of translation in LbetaT2 cells. Mol Cell Endocrinol (2009) 0.86
Conservation of mechanisms mediating gonadotrophin-releasing hormone 1 stimulation of human luteinizing hormone beta subunit transcription. Mol Hum Reprod (2008) 0.83
Gonadotropin-releasing hormone activates the equine luteinizing hormone beta promoter through a protein kinase C/mitogen-activated protein kinase pathway. Biol Reprod (1999) 0.83
PPARG regulates gonadotropin-releasing hormone signaling in LbetaT2 cells in vitro and pituitary gonadotroph function in vivo in mice. Biol Reprod (2010) 0.83
Modulation of anterior pituitary luteinizing hormone response to gonadotropin-releasing hormone by insulin-like growth factor I in vitro. Fertil Steril (1995) 0.82
Cyclical expression of egr-1/NGFI-A in the rat anterior pituitary: a molecular signal for ovulation? J Neuroendocrinol (2000) 0.80
Transcriptional regulation of the human glycoprotein hormone common alpha subunit gene by cAMP-response-element-binding protein (CREB)-binding protein (CBP)/p300 and p53. Biochem J (2002) 0.78
Regulation of pituitary gonadotrophin gene expression. Hum Reprod Update (1995) 0.78
Ultrastructural immunolocalization of IGF-1 and insulin receptors in rat pituitary culture: evidence of a functional interaction between gonadotroph and lactotroph cells. Cell Tissue Res (2006) 0.77
Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein. Cell (2009) 2.69
Synthesis, structure analysis and cytotoxicity studies of novel unsymmetrically n,n'-substituted ureas from dehydroabietic Acid. Chem Pharm Bull (Tokyo) (2008) 2.48
Meta-analysis: eradication of Helicobacter pylori infection is associated with the development of endoscopic gastroesophageal reflux disease. Eur J Gastroenterol Hepatol (2013) 2.17
Metformin activates an atypical PKC-CBP pathway to promote neurogenesis and enhance spatial memory formation. Cell Stem Cell (2012) 1.74
Long-term surveillance of growth hormone therapy. J Clin Endocrinol Metab (2011) 1.64
Timing and completion of puberty in female mice depend on estrogen receptor alpha-signaling in kisspeptin neurons. Proc Natl Acad Sci U S A (2010) 1.62
Insulin regulation of hepatic gluconeogenesis through phosphorylation of CREB-binding protein. Nat Med (2004) 1.53
Pharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans. Drug Metab Dispos (2012) 1.48
Increased pancreatic beta-cell proliferation mediated by CREB binding protein gene activation. Mol Cell Biol (2006) 1.42
Molecular basis of combined pituitary hormone deficiencies. Endocr Rev (2002) 1.38
Update of guidelines for the use of growth hormone in children: the Lawson Wilkins Pediatric Endocrinology Society Drug and Therapeutics Committee. J Pediatr (2003) 1.36
Minireview: Thyrotropin-releasing hormone and the thyroid hormone feedback mechanism. Endocrinology (2009) 1.36
CBP histone acetyltransferase activity regulates embryonic neural differentiation in the normal and Rubinstein-Taybi syndrome brain. Dev Cell (2010) 1.25
Thyroid hormone receptor DNA binding is required for both positive and negative gene regulation. J Biol Chem (2002) 1.21
Impaired estrogen feedback and infertility in female mice with pituitary-specific deletion of estrogen receptor alpha (ESR1). Biol Reprod (2009) 1.21
Rescue of obesity-induced infertility in female mice due to a pituitary-specific knockout of the insulin receptor. Cell Metab (2010) 1.20
Genetic overlap in Kallmann syndrome, combined pituitary hormone deficiency, and septo-optic dysplasia. J Clin Endocrinol Metab (2012) 1.18
Exendin-4 stimulation of cyclin A2 in beta-cell proliferation. Diabetes (2008) 1.17
Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo. J Clin Invest (2003) 1.16
An estrogen receptor-alpha knock-in mutation provides evidence of ligand-independent signaling and allows modulation of ligand-induced pathways in vivo. Endocrinology (2008) 1.16
Divergent roles of growth factors in the GnRH regulation of puberty in mice. J Clin Invest (2010) 1.13
A thyroid hormone receptor mutation that dissociates thyroid hormone regulation of gene expression in vivo. Proc Natl Acad Sci U S A (2009) 1.08
An intact DNA-binding domain is not required for peroxisome proliferator-activated receptor gamma (PPARgamma) binding and activation on some PPAR response elements. J Biol Chem (2004) 1.06
EST pipeline system: detailed and automated EST data processing and mining. Genomics Proteomics Bioinformatics (2003) 1.06
Pubertal development and menarche. Ann N Y Acad Sci (2008) 1.06
Generation and characterization of a complete null estrogen receptor alpha mouse using Cre/LoxP technology. Mol Cell Biochem (2008) 1.06
Disrupted kisspeptin signaling in GnRH neurons leads to hypogonadotrophic hypogonadism. Mol Endocrinol (2014) 1.05
Negative regulation by thyroid hormone receptor requires an intact coactivator-binding surface. J Clin Invest (2005) 1.05
Enhanced repression by HESX1 as a cause of hypopituitarism and septooptic dysplasia. J Clin Endocrinol Metab (2003) 1.04
Defects of prostate development and reproductive system in the estrogen receptor-alpha null male mice. Endocrinology (2008) 1.01
Protective immunization of horses with a recombinant canarypox virus vectored vaccine co-expressing genes encoding the outer capsid proteins of African horse sickness virus. Vaccine (2009) 1.01
Kisspeptin increases GnRH mRNA expression and secretion in GnRH secreting neuronal cell lines. Mol Cell Endocrinol (2009) 1.01
Cross-talk between thyroid hormone receptor and liver X receptor regulatory pathways is revealed in a thyroid hormone resistance mouse model. J Biol Chem (2005) 1.00
Estrogenic regulation of the GnRH neuron. Front Endocrinol (Lausanne) (2012) 1.00
Community and family perspectives on addressing overweight in urban, African-American youth. J Gen Intern Med (2007) 1.00
Endocrinology of female puberty. Curr Opin Endocrinol Diabetes Obes (2009) 1.00
A novel dominant negative mutation of OTX2 associated with combined pituitary hormone deficiency. J Clin Endocrinol Metab (2008) 0.99
Transcriptional co-activator p300 maintains basal hepatic gluconeogenesis. J Biol Chem (2012) 0.99
Crystal structure of the 1:2:2 adduct of piperazine, o-phthalic acid and water. Anal Sci (2003) 0.99
Jak2 is necessary for neuroendocrine control of female reproduction. J Neurosci (2011) 0.99
A novel technique for temporally regulated cell type-specific Cre expression and recombination in the pituitary gonadotroph. J Mol Endocrinol (2006) 0.99
Egr-1 binds the GnRH promoter to mediate the increase in gene expression by insulin. Mol Cell Endocrinol (2007) 0.98
Dominant role of thyrotropin-releasing hormone in the hypothalamic-pituitary-thyroid axis. J Biol Chem (2005) 0.97
Deletion of Otx2 in GnRH neurons results in a mouse model of hypogonadotropic hypogonadism. Mol Endocrinol (2011) 0.97
Recombinant canarypox virus vaccine co-expressing genes encoding the VP2 and VP5 outer capsid proteins of bluetongue virus induces high level protection in sheep. Vaccine (2006) 0.97
Obesity-induced infertility and hyperandrogenism are corrected by deletion of the insulin receptor in the ovarian theca cell. Diabetes (2013) 0.97
[Study on objectively evaluating skin aging according to areas of skin texture]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi (2015) 0.96
Edoxaban administration following enoxaparin: a pharmacodynamic, pharmacokinetic, and tolerability assessment in human subjects. Thromb Haemost (2012) 0.96
Extinction of aversive memories associated with morphine withdrawal requires ERK-mediated epigenetic regulation of brain-derived neurotrophic factor transcription in the rat ventromedial prefrontal cortex. J Neurosci (2012) 0.96
Estrogen regulation of gene expression in GnRH neurons. Mol Cell Endocrinol (2009) 0.96
Chemical genetics suggests a critical role for lysyl oxidase in zebrafish notochord morphogenesis. Mol Biosyst (2006) 0.95
Loss of epithelial oestrogen receptor α inhibits oestrogen-stimulated prostate proliferation and squamous metaplasia via in vivo tissue selective knockout models. J Pathol (2011) 0.94
Positive, but not negative feedback actions of estradiol in adult female mice require estrogen receptor α in kisspeptin neurons. Endocrinology (2014) 0.94
Low concentrations of metformin suppress glucose production in hepatocytes through AMP-activated protein kinase (AMPK). J Biol Chem (2014) 0.93
Promoter sequences targeting tissue-specific gene expression of hypothalamic and ovarian gonadotropin-releasing hormone in vivo. J Biol Chem (2001) 0.93
Involvement of mitochondrial pathway in triptolide-induced cytotoxicity in human normal liver L-02 cells. Biol Pharm Bull (2008) 0.93
The molecular basis of hypopituitarism. Trends Endocrinol Metab (2009) 0.93
Thyroid hormone action is required for normal cone opsin expression during mouse retinal development. Invest Ophthalmol Vis Sci (2008) 0.92
Insulin augments GnRH-stimulated LHbeta gene expression by Egr-1. Mol Cell Endocrinol (2006) 0.92
Cytotoxic effects and pro-apoptotic mechanism of TBIDOM, a novel dehydroabietylamine derivative, on human hepatocellular carcinoma SMMC-7721 cells. J Pharm Pharmacol (2008) 0.91
The effect of rifampin on the pharmacokinetics of edoxaban in healthy adults. Clin Drug Investig (2015) 0.91
In vivo identification of a 107-base pair promoter element mediating neuron-specific expression of mouse gonadotropin-releasing hormone. Mol Endocrinol (2006) 0.91
Targeted deletion of somatotroph insulin-like growth factor-I signaling in a cell-specific knockout mouse model. Mol Endocrinol (2010) 0.91
Pharmacokinetics, safety, and tolerability of edoxaban in end-stage renal disease subjects undergoing haemodialysis. Thromb Haemost (2015) 0.90
Structure elucidation of Sch 538415, a novel acyl carrier protein synthase inhibitor from a microorganism. Bioorg Med Chem Lett (2003) 0.90
Control of Foxo1 gene expression by co-activator P300. J Biol Chem (2013) 0.90
In vivo interaction of steroid receptor coactivator (SRC)-1 and the activation function-2 domain of the thyroid hormone receptor (TR) beta in TRbeta E457A knock-in and SRC-1 knockout mice. Endocrinology (2009) 0.90
Fundamentally distinct roles of thyroid hormone receptor isoforms in a thyrotroph cell line are due to differential DNA binding. Mol Endocrinol (2012) 0.90
Insulin regulation of GnRH gene expression through MAP kinase signaling pathways. Mol Cell Endocrinol (2005) 0.90
Site-Directed Mutagenesis of the Sterol Methyl Transferase Active Site from Saccharomyces cerevisiae Results in Formation of Novel 24-Ethyl Sterols. J Org Chem (1999) 0.90
Novel mutations associated with combined pituitary hormone deficiency. J Mol Endocrinol (2011) 0.89
Activation of basal gluconeogenesis by coactivator p300 maintains hepatic glycogen storage. Mol Endocrinol (2013) 0.89
Kaempferol protects against doxorubicin-induced cardiotoxicity in vivo and in vitro. Toxicology (2011) 0.89
Aromatase promoter I.f is regulated by estrogen receptor alpha (ESR1) in mouse hypothalamic neuronal cell lines. Biol Reprod (2009) 0.89
Reproductive tissues maintain insulin sensitivity in diet-induced obesity. Diabetes (2011) 0.88