Published in J Biol Chem on October 15, 2003
Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes. Proc Natl Acad Sci U S A (2004) 3.39
REST regulates distinct transcriptional networks in embryonic and neural stem cells. PLoS Biol (2008) 2.12
Distinct profiles of REST interactions with its target genes at different stages of neuronal development. Mol Biol Cell (2005) 1.52
The transcription factor REST is lost in aggressive breast cancer. PLoS Genet (2010) 1.17
Targeting Huntington's disease through histone deacetylases. Clin Epigenetics (2011) 1.13
BRG1 chromatin remodeling activity is required for efficient chromatin binding by repressor element 1-silencing transcription factor (REST) and facilitates REST-mediated repression. J Biol Chem (2006) 1.10
Zebrafish Prickle1b mediates facial branchiomotor neuron migration via a farnesylation-dependent nuclear activity. Development (2011) 1.02
The repressor element 1-silencing transcription factor regulates heart-specific gene expression using multiple chromatin-modifying complexes. Mol Cell Biol (2007) 0.99
The transcription factor NRSF contributes to epileptogenesis by selective repression of a subset of target genes. Elife (2014) 0.96
In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons. Hum Mol Genet (2010) 0.96
Zebrafish rest regulates developmental gene expression but not neurogenesis. Development (2012) 0.95
EWS-FLI-1 regulates the neuronal repressor gene REST, which controls Ewing sarcoma growth and vascular morphology. Cancer (2014) 0.88
REST/NRSF governs the expression of dense-core vesicle gliosecretion in astrocytes. J Cell Biol (2011) 0.88
Comparison of REST cistromes across human cell types reveals common and context-specific functions. PLoS Comput Biol (2014) 0.85
Neural restrictive silencer factor and choline acetyltransferase expression in cerebral tissue of Alzheimer's Disease patients: A pilot study. Genet Mol Biol (2013) 0.79
Regulated expression of the Ras effector Rin1 in forebrain neurons. Mol Cell Neurosci (2009) 0.78
The Brain-Specific Neural Zinc Finger Transcription Factor 2b (NZF-2b/7ZFMyt1) Suppresses Cocaine Self-Administration in Rats. Front Behav Neurosci (2010) 0.78
REST is a crucial regulator for acquiring EMT-like and stemness phenotypes in hormone-refractory prostate cancer. Sci Rep (2017) 0.75
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
The landscape of histone modifications across 1% of the human genome in five human cell lines. Genome Res (2007) 5.67
Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes. Proc Natl Acad Sci U S A (2004) 3.39
Chromatin crosstalk in development and disease: lessons from REST. Nat Rev Genet (2007) 3.18
A microRNA-based gene dysregulation pathway in Huntington's disease. Neurobiol Dis (2007) 2.41
REST regulates distinct transcriptional networks in embryonic and neural stem cells. PLoS Biol (2008) 2.12
Making a firm decision: multifaceted regulation of cell fate in the early mouse embryo. Nat Rev Genet (2009) 1.94
Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury. Pain (2011) 1.87
Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication. Nucleic Acids Res (2006) 1.62
Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation. Mol Cell (2005) 1.58
Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1.3 channel blockers. Cardiovasc Res (2010) 1.57
Distinct profiles of REST interactions with its target genes at different stages of neuronal development. Mol Biol Cell (2005) 1.52
Emergence of the pre-Bötzinger respiratory rhythm generator in the mouse embryo. J Neurosci (2005) 1.29
Involvement of P2X7 receptors in the regulation of neurotransmitter release in the rat hippocampus. J Neurochem (2002) 1.29
Evidence for inhibition mediated by coassembly of GABAA and GABAC receptor subunits in native central neurons. J Neurosci (2004) 1.19
Regulation of neural macroRNAs by the transcriptional repressor REST. RNA (2008) 1.18
Sharp wave-like activity in the hippocampus in vitro in mice lacking the gap junction protein connexin 36. J Neurophysiol (2003) 1.16
Cross-regulation between an alternative splicing activator and a transcription repressor controls neurogenesis. Mol Cell (2011) 1.15
Identifying gene regulatory elements by genomic microarray mapping of DNaseI hypersensitive sites. Genome Res (2006) 1.13
BRG1 chromatin remodeling activity is required for efficient chromatin binding by repressor element 1-silencing transcription factor (REST) and facilitates REST-mediated repression. J Biol Chem (2006) 1.10
Complex exon-intron marking by histone modifications is not determined solely by nucleosome distribution. PLoS One (2010) 1.09
Maternally and zygotically provided Cdx2 have novel and critical roles for early development of the mouse embryo. Dev Biol (2010) 1.07
Transcriptional control of KCNQ channel genes and the regulation of neuronal excitability. J Neurosci (2010) 1.07
RE1 Silencing transcription factor maintains a repressive chromatin environment in embryonic hippocampal neural stem cells. Stem Cells (2006) 1.05
Rest-mediated regulation of extracellular matrix is crucial for neural development. PLoS One (2008) 1.04
Evolution of the vertebrate gene regulatory network controlled by the transcriptional repressor REST. Mol Biol Evol (2009) 1.02
Interaction of the repressor element 1-silencing transcription factor (REST) with target genes. J Mol Biol (2003) 1.02
Transcriptional dysregulation of coding and non-coding genes in cellular models of Huntington's disease. Biochem Soc Trans (2009) 1.01
Gene dysregulation in Huntington's disease: REST, microRNAs and beyond. Neuromolecular Med (2009) 1.01
Genomic approaches uncover increasing complexities in the regulatory landscape at the human SCL (TAL1) locus. PLoS One (2010) 0.99
The repressor element 1-silencing transcription factor regulates heart-specific gene expression using multiple chromatin-modifying complexes. Mol Cell Biol (2007) 0.99
Regulation of gene expression in the nervous system. Biochem J (2008) 0.97
Simvastatin inhibits TNFalpha-induced invasion of human cardiac myofibroblasts via both MMP-9-dependent and -independent mechanisms. J Mol Cell Cardiol (2007) 0.94
The transcriptional repressor REST is a critical regulator of the neurosecretory phenotype. J Neurochem (2006) 0.94
K(v)1.5 potassium channel gene regulation by Sp1 transcription factor and oxidative stress. Am J Physiol Heart Circ Physiol (2007) 0.94
HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain. Pain (2013) 0.91
Dysregulation of REST-regulated coding and non-coding RNAs in a cellular model of Huntington's disease. J Neurochem (2013) 0.91
Hypoxia-inducible factor-1α (HIF1α) switches on transient receptor potential ankyrin repeat 1 (TRPA1) gene expression via a hypoxia response element-like motif to modulate cytokine release. J Biol Chem (2012) 0.91
Repressor element 1 silencing transcription factor couples loss of pluripotency with neural induction and neural differentiation. Stem Cells (2012) 0.89
An ATP-gated ion channel at the cell nucleus. Nature (2002) 0.87
Less REST, more vascular disease? Regulation of cell cycle and migration of vascular smooth muscle cells. Cell Cycle (2006) 0.86
Rescue of gene expression by modified REST decoy oligonucleotides in a cellular model of Huntington's disease. J Neurochem (2010) 0.85
Neurodegeneration as an RNA disorder. Prog Neurobiol (2012) 0.85
An epigenetic signature of developmental potential in neural stem cells and early neurons. Stem Cells (2013) 0.84
Binding of the repressor complex REST-mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models. J Neurochem (2013) 0.80
Stimulation of Galphaq-coupled M1 muscarinic receptor causes reversible spectrin redistribution mediated by PLC, PKC and ROCK. J Cell Sci (2006) 0.80
Epigenetic mechanisms in development and disease. Biochem Soc Trans (2013) 0.78
Multiple promoters drive tissue-specific expression of the human M muscarinic acetylcholine receptor gene. J Neurochem (2004) 0.78
Ligand-binding activity and expression profile of annexins in Caenorhabditis elegans. J Biochem (2006) 0.78
Transcription of the M1 muscarinic receptor gene in neurons and neuronal progenitors of the embryonic rat forebrain. J Neurochem (2004) 0.77
Chromatin switching and transcriptional regulation in disease. Biochem Soc Trans (2008) 0.76
Concise review: a population shift view of cellular reprogramming. Stem Cells (2014) 0.76
KvDB; mining and mapping sequence variants in voltage-gated potassium channels. Hum Mutat (2010) 0.75
Identifying transcriptional regulatory regions using reporter genes and DNA-protein interactions by chromatin immunoprecipitation. Methods Mol Biol (2008) 0.75
From beads on a string to the pearls of regulation: the structure and dynamics of chromatin. Biochem Soc Trans (2012) 0.75
Pro-inflammatory mechanisms of a non-steroidal anti-inflammatory drug. Trends Pharmacol Sci (2002) 0.75