Published in Mol Pharmacol on November 01, 2003
Age-associated changes in immune and inflammatory responses: impact of vitamin E intervention. J Leukoc Biol (2008) 1.19
Cannabinoids and cancer: pros and cons of an antitumour strategy. Br J Pharmacol (2006) 1.18
CB(1) cannabinoid receptors and their associated proteins. Curr Med Chem (2010) 1.15
The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2. Gut (2005) 1.00
Endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 involves ceramide metabolic pathways. Blood (2005) 0.95
Interactions between CB(1) receptors and TRPV1 channels mediated by 12-HPETE are cytotoxic to mesencephalic dopaminergic neurons. Br J Pharmacol (2008) 0.79
Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity. Stem Cells (2015) 0.78
Brain CB₂ Receptors: Implications for Neuropsychiatric Disorders. Pharmaceuticals (Basel) (2010) 0.76
Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts. Nat Med (2006) 4.74
A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Cell (2010) 2.37
Reversal of pathological pain through specific spinal GABAA receptor subtypes. Nature (2008) 2.30
Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. FASEB J (2007) 2.00
Blockade of TNF-α rapidly inhibits pain responses in the central nervous system. Proc Natl Acad Sci U S A (2011) 1.95
The impact of unlicensed and off-label drug use on adverse drug reactions in paediatric patients. Drug Saf (2004) 1.57
Cyclooxygenase-2--10 years later. J Pharmacol Exp Ther (2002) 1.44
Engineering of vascularized transplantable bone tissues: induction of axial vascularization in an osteoconductive matrix using an arteriovenous loop. Tissue Eng (2006) 1.40
In vivo magnetic resonance imaging of dendritic cell migration into the draining lymph nodes of mice. Eur J Immunol (2006) 1.31
Spinal inflammatory hyperalgesia is mediated by prostaglandin E receptors of the EP2 subtype. J Clin Invest (2005) 1.30
Simultaneous determination of aceclofenac and three of its metabolites in human plasma by high-performance liquid chromatography. Biomed Chromatogr (2003) 1.29
Inhibition of cancer cell invasion by cannabinoids via increased expression of tissue inhibitor of matrix metalloproteinases-1. J Natl Cancer Inst (2007) 1.23
Survey of adverse drug reactions on a pediatric ward: a strategy for early and detailed detection. Pediatrics (2002) 1.23
Role of p-glycoprotein inhibition for drug interactions: evidence from in vitro and pharmacoepidemiological studies. Clin Pharmacokinet (2007) 1.14
Identification of adverse drug reactions in geriatric inpatients using a computerised drug database. Drugs Aging (2003) 1.12
A role for endocannabinoids in indomethacin-induced spinal antinociception. Eur J Pharmacol (2002) 1.10
Polymorphisms of TLR4: rapid genotyping and reduced response to lipopolysaccharide of TLR4 mutant alleles. Clin Chem (2002) 1.10
Caffeine accelerates absorption and enhances the analgesic effect of acetaminophen. J Clin Pharmacol (2007) 1.07
Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1. Biochem Pharmacol (2009) 1.07
Analgesic strategies beyond the inhibition of cyclooxygenases. Trends Pharmacol Sci (2006) 1.05
Lack of awareness of community-acquired adverse drug reactions upon hospital admission : dimensions and consequences of a dilemma. Drug Saf (2003) 1.03
Gene expression changes in blood after phlebotomy: implications for gene expression profiling. Blood (2002) 1.02
Antitumorigenic effects of cannabinoids beyond apoptosis. J Pharmacol Exp Ther (2009) 1.00
Combining functional magnetic resonance imaging with mouse genomics: new options in pain research. Neuroreport (2010) 0.96
Drug utilisation on a preterm and neonatal intensive care unit in Germany: a prospective, cohort-based analysis. Eur J Clin Pharmacol (2009) 0.96
Imaging of hyperalgesia in rats by functional MRI. Eur J Pain (2006) 0.95
Dipyrone elicits substantial inhibition of peripheral cyclooxygenases in humans: new insights into the pharmacology of an old analgesic. FASEB J (2007) 0.94
Stabilization of gene expression profiles in blood after phlebotomy. Clin Chem (2002) 0.94
15-Deoxy-Delta(12,14)-prostaglandin J2 inhibits the expression of proinflammatory genes in human blood monocytes via a PPAR-gamma-independent mechanism. Biochem Biophys Res Commun (2003) 0.94
Are computerised monitoring systems of value to improve pharmacovigilance in paediatric patients? Eur J Clin Pharmacol (2006) 0.94
Evaluation of NT-proBNP and high sensitivity C-reactive protein for predicting cardiovascular risk in patients with arthritis taking longterm nonsteroidal antiinflammatory drugs. J Rheumatol (2011) 0.93
Paracetamol, ibuprofen, or a combination of both drugs against knee pain: an excellent new randomised clinical trial answers old questions and suggests new therapeutic recommendations. Ann Rheum Dis (2011) 0.93
Regulation of IL-13 synthesis in human lymphocytes: implications for asthma therapy. Br J Pharmacol (2002) 0.92
Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1. FASEB J (2011) 0.92
Latanoprost induces matrix metalloproteinase-1 expression in human nonpigmented ciliary epithelial cells through a cyclooxygenase-2-dependent mechanism. FASEB J (2005) 0.91
COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells. Mol Cancer Ther (2012) 0.89
Celecoxib inhibits metabolism of cytochrome P450 2D6 substrate metoprolol in humans. Clin Pharmacol Ther (2003) 0.88
Simultaneous determination of leflunomide and its active metabolite, A77 1726, in human plasma by high-performance liquid chromatography. Biomed Chromatogr (2003) 0.88
R(+)-methanandamide and other cannabinoids induce the expression of cyclooxygenase-2 and matrix metalloproteinases in human nonpigmented ciliary epithelial cells. J Pharmacol Exp Ther (2005) 0.88
The discovery and development of antiinflammatory drugs. Arthritis Rheum (2004) 0.88
Drug insight: cyclo-oxygenase-2 inhibitors--a critical appraisal. Nat Clin Pract Rheumatol (2007) 0.87
Kinetics and functional characterization of the glycine receptor alpha2 and alpha3 subunit. Neurosci Lett (2007) 0.87
Normal sensitivity to acute pain, but increased inflammatory hyperalgesia in mice lacking the nociceptin precursor polypeptide or the nociceptin receptor. Eur J Neurosci (2003) 0.87
Up-regulation of cyclooxygenase-2 expression is involved in R(+)-methanandamide-induced apoptotic death of human neuroglioma cells. Mol Pharmacol (2004) 0.87
Intrinsic versus extrinsic vascularization in tissue engineering. Adv Exp Med Biol (2006) 0.87
More pronounced inhibition of cyclooxygenase 2, increase in blood pressure, and reduction of heart rate by treatment with diclofenac compared with celecoxib and rofecoxib. Arthritis Rheum (2006) 0.87
Paracetamol and cyclooxygenase inhibition: is there a cause for concern? Ann Rheum Dis (2011) 0.86
Prostaglandin E2 induces cyclooxygenase-2 expression in human non-pigmented ciliary epithelial cells through activation of p38 and p42/44 mitogen-activated protein kinases. Biochem Biophys Res Commun (2005) 0.86
Inhibitors of mitogen-activated protein kinases differentially regulate costimulated T cell cytokine production and mouse airway eosinophilia. Respir Res (2005) 0.86
Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer cells. Pharm Res (2010) 0.86
Pain and osteoarthritis: new drugs and mechanisms. Curr Opin Rheumatol (2004) 0.86
Lipopolysaccharide-induced lung inflammation is inhibited by neutralization of GM-CSF. Eur J Pharmacol (2006) 0.85
Consumption of analgesics before a marathon and the incidence of cardiovascular, gastrointestinal and renal problems: a cohort study. BMJ Open (2013) 0.85
E-pharmacovigilance: development and implementation of a computable knowledge base to identify adverse drug reactions. Br J Clin Pharmacol (2013) 0.85
Aceclofenac spares cyclooxygenase 1 as a result of limited but sustained biotransformation to diclofenac. Clin Pharmacol Ther (2003) 0.84
R(+)-methanandamide-induced cyclooxygenase-2 expression in H4 human neuroglioma cells: possible involvement of membrane lipid rafts. Biochem Biophys Res Commun (2004) 0.84
Synergistic effects of the anti-cholinergic R,R-glycopyrrolate with anti-inflammatory drugs. Biochem Pharmacol (2006) 0.83
R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway. Pharm Res (2008) 0.83
Can drug removals involving cyclooxygenase-2 inhibitors be avoided? A plea for human pharmacology. Trends Pharmacol Sci (2008) 0.83
Investigation of the pharmacokinetics of celecoxib by liquid chromatography-mass spectrometry. Biomed Chromatogr (2002) 0.83
Using pharmacokinetic principles to optimize pain therapy. Nat Rev Rheumatol (2010) 0.83
Determination of the endocannabinoid anandamide in human plasma by high-performance liquid chromatography. Biomed Chromatogr (2006) 0.82
Influence of cyclooxygenase inhibitors on the function of the prostaglandin transporter organic anion-transporting polypeptide 2A1 expressed in human gastroduodenal mucosa. J Pharmacol Exp Ther (2009) 0.82
Bioavailability of diclofenac potassium at low doses. Br J Clin Pharmacol (2005) 0.81
Hypoxia induced chemokine expression in nasal epithelial cells: development of an in vitro model for chronic rhinosinusitis. ALTEX (2006) 0.81
Absorption and distribution of etoricoxib in plasma, CSF, and wound tissue in patients following hip surgery--a pilot study. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.81
N-terminal prohormone brain natriuretic peptide: a biomarker for detecting cardiovascular risks in patients with rheumatoid arthritis or osteoarthritis? Ann Rheum Dis (2007) 0.81
A simple method for simultaneous determination of N-arachidonoylethanolamine, N-oleoylethanolamine, N-palmitoylethanolamine and 2-arachidonoylglycerol in human cells. Anal Bioanal Chem (2014) 0.80
Effect of amiodarone on the plasma levels of metoprolol. Am J Cardiol (2004) 0.80
Induction but not inhibition of COX-2 confers human lung cancer cell apoptosis by celecoxib. J Lipid Res (2013) 0.80
Cytochrome p450 polymorphisms in geriatric patients: impact on adverse drug reactions--a pilot study. Drugs Aging (2005) 0.79
Cardiovascular effects of selective COX-2 inhibition: is there a class effect? The International COX-2 Study Group. J Rheumatol (2006) 0.79
Herbal remedies for asthma treatment: between myth and reality. Drugs Today (Barc) (2002) 0.79
Cyclooxygenase-2 and tissue inhibitor of matrix metalloproteinases-1 confer the antimigratory effect of cannabinoids on human trabecular meshwork cells. Biochem Pharmacol (2010) 0.79
Cytokine profiles of cord and adult blood leukocytes: differences in expression are due to differences in expression and activation of transcription factors. BMC Immunol (2007) 0.79
Lateralization of responses to vibrissal stimulation: connectivity and information integration in the rat sensory-motor cortex assessed with fMRI. Neuroimage (2012) 0.79
New problems arising from old drugs: second-generation effects of acetaminophen. Expert Rev Clin Pharmacol (2014) 0.79
The effects of colchicine and hydroxychloroquine on the cyclo-oxygenases COX-1 and COX-2. Rheumatol Int (2004) 0.78
Advances in NSAID development: evolution of diclofenac products using pharmaceutical technology. Drugs (2015) 0.77
Osteoporosis in a young woman after 6 years of levonorgestrel administration from intrauterine devices? BMJ Case Rep (2009) 0.77
Aspirin and acetaminophen: should they be available over the counter? Curr Rheumatol Rep (2009) 0.77
Simultaneous determination of oxycodone and its major metabolite, noroxycodone, in human plasma by high-performance liquid chromatography. Biomed Chromatogr (2005) 0.76
Refinement and reduction in animal experimentation: options for new imaging techniques. ALTEX (2008) 0.76
Synthesis of thia-analogous indirubin N-Glycosides and their influence on melanoma cell growth and apoptosis. ChemMedChem (2010) 0.76
Anti-inflammatory effects of a cyclosporine receptor-binding compound, D-43787. J Pharmacol Exp Ther (2002) 0.76
Platelet inhibitory effects of OTC doses of naproxen sodium compared with prescription dose naproxen sodium and low-dose aspirin. Curr Med Res Opin (2009) 0.76
A role for cyclooxygenase-1 in neuropathic pain? Anesthesiology (2003) 0.75
A liquid chromatography-mass spectrometry method for the quantification of both etoricoxib and valdecoxib in human plasma. Biomed Chromatogr (2005) 0.75