Published in J Exp Med on December 01, 1992
Gain-of-function mutations of the p53 gene induce lymphohematopoietic metastatic potential and tissue invasiveness. Am J Pathol (1994) 1.39
Experimental infection of NOD/SCID mice reconstituted with human CD34+ cells with Epstein-Barr virus. J Virol (2004) 1.24
An Epstein-Barr virus-associated superantigen. J Exp Med (1996) 1.17
Lymphomas can develop from B cells chronically helped by idiotype-specific T cells. J Exp Med (2007) 1.05
The role of EBV in post-transplant malignancies: a review. J Clin Pathol (2000) 1.02
The expression of Epstein-Barr virus latent proteins is related to the pathological features of post-transplant lymphoproliferative disorders. Am J Pathol (1995) 0.97
Novel mouse xenograft models reveal a critical role of CD4+ T cells in the proliferation of EBV-infected T and NK cells. PLoS Pathog (2011) 0.94
Low-dose interleukin 2 prevents the development of Epstein-Barr virus (EBV)-associated lymphoproliferative disease in scid/scid mice reconstituted i.p. with EBV-seropositive human peripheral blood lymphocytes. Proc Natl Acad Sci U S A (1994) 0.94
Epstein-Barr virus nuclear antigen leader protein induces expression of thymus- and activation-regulated chemokine in B cells. J Virol (2004) 0.92
Differential Epstein-Barr virus gene expression in B-cell subsets recovered from lymphomas in SCID mice after transplantation of human peripheral blood lymphocytes. J Virol (1995) 0.91
Functional analysis of the CD4(+) T-cell response to Epstein-Barr virus: T-cell-mediated activation of resting B cells and induction of viral BZLF1 expression. J Virol (2000) 0.89
Virus-encoded superantigens. Microbiol Rev (1996) 0.89
GM-CSF and IL-2 induce specific cellular immunity and provide protection against Epstein-Barr virus lymphoproliferative disorder. J Clin Invest (2001) 0.88
LMP1-deficient Epstein-Barr virus mutant requires T cells for lymphomagenesis. J Clin Invest (2014) 0.82
In vitro cytokine production and growth inhibition of lymphoblastoid cell lines by CD4+ T cells from Epstein-Barr virus (EBV) seropositive donors. Clin Exp Immunol (2001) 0.82
Humanized mouse models of epstein-barr virus infection and associated diseases. Pathogens (2013) 0.78
CD4 T cell responses in latent and chronic viral infections. Front Immunol (2013) 0.77
Fighting Viral Infections and Virus-Driven Tumors with Cytotoxic CD4(+) T Cells. Front Immunol (2017) 0.75
Are natural killer cells the key to treating Epstein-Barr virus-associated lymphoproliferative disorders? J Clin Invest (2001) 0.75
A severe combined immunodeficiency mutation in the mouse. Nature (1983) 13.99
The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. Science (1988) 9.05
Transfer of a functional human immune system to mice with severe combined immunodeficiency. Nature (1988) 6.38
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. Nature (1991) 6.30
Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones. Science (1991) 6.12
Increased incidence of lymphoproliferative disorder after immunosuppression with the monoclonal antibody OKT3 in cardiac-transplant recipients. N Engl J Med (1990) 3.88
Natural killer (NK) cells are present in mice with severe combined immunodeficiency (scid). J Immunol (1985) 3.69
Severe combined immunodeficiency (SCID) in the mouse. Pathology, reconstitution, neoplasms. Am J Pathol (1985) 2.80
Epstein-Barr virus (EBV)-associated lymphoproliferative disease in the SCID mouse model: implications for the pathogenesis of EBV-positive lymphomas in man. J Exp Med (1991) 2.20
HIV-1-specific B cell activation. A major constituent of spontaneous B cell activation during HIV-1 infection. J Immunol (1989) 1.66
Human mature T cells that are anergic in vivo prevail in SCID mice reconstituted with human peripheral blood. J Exp Med (1992) 1.65
Multiple monoclonal B cell expansions and c-myc oncogene rearrangements in acquired immune deficiency syndrome-related lymphoproliferative disorders. Implications for lymphomagenesis. J Exp Med (1986) 1.60
Epstein-Barr virus induces aggressive lymphoproliferative disorders of human B cell origin in SCID/hu chimeric mice. J Clin Invest (1990) 1.49
The immunosuppressive activity of L-leucyl-L-leucine methyl ester: selective ablation of cytotoxic lymphocytes and monocytes. J Immunol (1986) 1.46
Epstein-Barr virus infection and immunoregulation in man. Adv Immunol (1985) 1.36
NK and T cell subsets regulate antibody production by human in vivo antigen-induced lymphoblastoid B cells. J Immunol (1984) 1.34
Development of non-Hodgkin lymphoma in a cohort of patients with severe human immunodeficiency virus (HIV) infection on long-term antiretroviral therapy. Ann Intern Med (1990) 1.31
Human monoclonal antibodies produced by primary in vitro immunization of peripheral blood lymphocytes. Proc Natl Acad Sci U S A (1988) 1.26
Tumors of the immunocompromised patient. Annu Rev Med (1988) 1.08
SCID mouse model of Epstein-Barr virus-induced lymphomagenesis of immunodeficient humans. Int J Cancer (1991) 1.01
The opportunistic tumors of immune deficiency. Adv Cancer Res (1990) 0.98
CD4 epitope masking by gp120/anti-gp120 antibody complexes. A potential mechanism for CD4+ cell function down-regulation in AIDS patients. J Immunol (1992) 0.92
B-cell activation during HIV-1 infection. III. Down-regulating effect of mitogens. AIDS (1991) 0.87
Effect of cyclosporin A on lymphopoiesis. III. Augmentation of the generation of natural killer cells in bone marrow transplanted mice treated with cyclosporin A. J Immunol (1991) 0.83
Cyclosporin A renders target cells resistant to immune cytolysis. Eur J Immunol (1991) 0.83
Immunologic induction of malignant lymphoma: identification of donor and host tumors in the graft-versus-host model. J Natl Cancer Inst (1975) 0.82
Host and tumor modifications associated with serial heterotransplantation of tumors through immunologically tolerant animals. Cancer Res (1970) 0.81
Role of Epstein-Barr virus and interleukin 6 in the development of lymphomas of human origin in SCID mice engrafted with human tonsillar mononuclear cells. J Gen Virol (1992) 0.78
Genetic control of the CD4/CD8 T-cell ratio in humans. Nat Med (1995) 2.75
Radiotherapy versus radiotherapy enhanced by cisplatin in stage III non-small cell lung cancer. Int J Radiat Oncol Biol Phys (1992) 2.65
CD4: CD8 ratio and HIV infection: the "tap-and-drain' hypothesis. Immunol Today (1996) 2.19
Antigen detection, virus culture, polymerase chain reaction, and in vitro antibody production in the diagnosis of vertically transmitted HIV-1 infection. AIDS (1991) 1.97
Burdens and benefits of adjuvant cyclophosphamide, methotrexate, and fluorouracil and tamoxifen for elderly patients with breast cancer: the International Breast Cancer Study Group Trial VII. J Clin Oncol (2000) 1.92
Identifying breast cancer patients at high risk for bone metastases. J Clin Oncol (2000) 1.91
Early start of adjuvant chemotherapy may improve treatment outcome for premenopausal breast cancer patients with tumors not expressing estrogen receptors. The International Breast Cancer Study Group. J Clin Oncol (2000) 1.81
HIV-1-specific B cell activation. A major constituent of spontaneous B cell activation during HIV-1 infection. J Immunol (1989) 1.66
Tumor outgrowth in peripheral blood mononuclear cell-injected SCID mice is not associated with early Epstein-Barr virus reactivation. Leukemia (2003) 1.40
High incidence of central nervous system involvement in patients with metastatic or locally advanced breast cancer treated with epirubicin and docetaxel. Ann Oncol (2001) 1.38
Evaluation of widely used models for predicting BRCA1 and BRCA2 mutations. J Med Genet (2004) 1.33
Extrapulmonary small cell carcinoma: a single-institution experience and review of the literature. Ann Oncol (1994) 1.27
Differential response to the cytopathic effects of human T-cell lymphotropic virus type III (HTLV-III) superinfection in T4+ (helper) and T8+ (suppressor) T-cell clones transformed by HTLV-I. Proc Natl Acad Sci U S A (1986) 1.16
Identification of a 3 kb Alu-mediated BRCA1 gene rearrangement in two breast/ovarian cancer families. Oncogene (1999) 1.14
The pancreatic cancer cell line MIA PaCa2 produces one or more factors able to induce hyperglycemia in SCID mice. Anticancer Res (1996) 1.13
HPV16 genetic variation and the development of cervical cancer worldwide. Br J Cancer (2012) 1.13
Amelanotic/hypomelanotic melanoma: clinical and dermoscopic features. Br J Dermatol (2004) 1.11
Source and route of microbial colonisation of parenteral nutrition catheters. Lancet (1989) 1.11
Nucleic acid sequence and oncogenic properties of the HZ2 feline sarcoma virus v-abl insert. J Virol (1987) 1.10
Pattern of antibody response against the V3 loop in children with vertically acquired immunodeficiency virus type 1 (HIV-1) infection. AIDS Res Hum Retroviruses (1993) 1.09
Wnt activation promotes neuronal differentiation of glioblastoma. Cell Death Dis (2013) 1.08
New insights into human papillomavirus-associated head and neck squamous cell carcinoma. Acta Otorhinolaryngol Ital (2013) 1.07
Customizing CellSearch platform. Cytometry A (2013) 1.07
Moloney murine leukemia virus tolerance in anti-CD4 monoclonal antibody-treated adult mice. J Immunol (1991) 1.06
Large genomic deletions inactivate the BRCA2 gene in breast cancer families. J Med Genet (2005) 1.04
BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expression. Cell Death Dis (2012) 1.04
Identification of human papillomavirus types in male urethral condylomata acuminata by in situ hybridization. Hum Pathol (1987) 1.02
The Italian multi-centre project on evaluation of MRI and other imaging modalities in early detection of breast cancer in subjects at high genetic risk. J Exp Clin Cancer Res (2002) 1.02
HIV-1 induces down-regulation of bcl-2 expression and death by apoptosis of EBV-immortalized B cells: a model for a persistent "self-limiting" HIV-1 infection. Virology (1994) 1.02
MLR3 molecule is an activation antigen shared by human B, T lymphocytes and T cell precursors. Eur J Immunol (1989) 1.01
Characterization of human papilloma virus types in condylomata acuminata in children by in situ hybridization. Lab Invest (1987) 1.00
Does the information level of cancer patients correlate with quality of life? A prospective study. Tumori (1999) 1.00
Human T-lymphotropic virus type I transcriptional regulation by methylation. Cancer Res (1990) 1.00
B cell activation during HIV-1 infection. II. Cell-to-cell interactions and cytokine requirement. J Immunol (1991) 1.00
In vitro studies of HIV-1 infection in thymic lymphocytes: a putative role of the thymus in AIDS pathogenesis. AIDS Res Hum Retroviruses (1990) 1.00
Live attenuated simian immunodeficiency virus prevents super-infection by cloned SIVmac251 in cynomolgus monkeys. J Gen Virol (1997) 0.98
Patients compliance in an early detection program for upper aero-digestive tract tumours in north-eastern Italy. Soz Praventivmed (1990) 0.98
MTHFR gene polymorphism and severe toxicity during adjuvant treatment of early breast cancer with cyclophosphamide, methotrexate, and fluorouracil (CMF) Ann Oncol (2000) 0.98
Combined radiotherapy and chemotherapy versus radiotherapy alone in locally advanced epidermoid bronchogenic carcinoma. A randomized study. Cancer (1990) 0.97
Percutaneous hepatic vein isolation and high-dose hepatic arterial infusion chemotherapy for unresectable liver tumors. J Clin Oncol (1994) 0.97
Use of a high-risk human papillomavirus DNA test as the primary test in a cervical cancer screening programme: a population-based cohort study. BJOG (2013) 0.97
Heterogeneous bioenergetic behaviour of subsarcolemmal and intermyofibrillar mitochondria in fed and fasted rats. Cell Mol Life Sci (2006) 0.95
Identification of seven new BRCA1 germline mutations in Italian breast and breast/ovarian cancer families. Cancer Res (1996) 0.95
CD4 and CD8 T lymphocyte inheritance. Evidence for major autosomal recessive genes. Hum Genet (1999) 0.95
An alternatively spliced form of CD79b gene may account for altered B-cell receptor expression in B-chronic lymphocytic leukemia. Blood (1999) 0.94
Skeletal muscle subsarcolemmal mitochondrial dysfunction in high-fat fed rats exhibiting impaired glucose homeostasis. Int J Obes (Lond) (2007) 0.93
Dynamic changes of live/apoptotic circulating tumour cells as predictive marker of response to sunitinib in metastatic renal cancer. Br J Cancer (2012) 0.93
Relationship between the V3 loop and the phenotypes of human immunodeficiency virus type 1 (HIV-1) isolates from children perinatally infected with HIV-1. J Virol (1995) 0.92
Notch3-mediated regulation of MKP-1 levels promotes survival of T acute lymphoblastic leukemia cells. Leukemia (2011) 0.92
CD4 epitope masking by gp120/anti-gp120 antibody complexes. A potential mechanism for CD4+ cell function down-regulation in AIDS patients. J Immunol (1992) 0.92
Uncoupling of growth inhibition and differentiation in dexamethasone-treated human rhabdomyosarcoma cells. Br J Cancer (1993) 0.90
Dermoscopic criteria for melanoma in situ are similar to those for early invasive melanoma. Cancer (2001) 0.90
Timing of CMF chemotherapy in combination with tamoxifen in postmenopausal women with breast cancer: role of endocrine responsiveness of the tumor. Ann Oncol (2005) 0.90
Vulvar carcinoma in a 12-year-old girl with vertically acquired human immunodeficiency virus infection. Pediatrics (2000) 0.90
B non-Hodgkin's lymphoma in a haemophilia patient with idiopathic CD4+ T-lymphocytopenia. Leuk Lymphoma (1996) 0.89
HIV-1 infection of the thymus: evidence for a cytopathic and thymotropic viral variant in vivo. AIDS Res Hum Retroviruses (1995) 0.89
Thymidine phosphorylase expression is associated with time to progression in patients receiving low-dose, docetaxel-modulated capecitabine for metastatic breast cancer. Ann Oncol (2008) 0.88
Rapid identification of viable retrovirus-transduced cells using the green fluorescent protein as a marker. Gene Ther (1997) 0.88
Lack of association between androgen receptor CAG polymorphism and familial breast/ovarian cancer. Cancer Lett (2001) 0.88
Quantifying trade-offs: quality of life and quality-adjusted survival in a randomised trial of chemotherapy in postmenopausal patients with lymph node-negative breast cancer. Br J Cancer (2004) 0.88
Frequency of a mutated CCR-5 allele (delta32) among Italian healthy donors and individuals at risk of parenteral HIV infection. AIDS Res Hum Retroviruses (1999) 0.88
Synthetic peptides from the principal neutralizing domain of human immunodeficiency virus type 1 (HIV-1) enhance HIV-1 infection through a CD4-dependent mechanism. Virology (1991) 0.87
Myosin isoform expression in rat rhabdomyosarcoma induced by Moloney murine sarcoma virus. J Cancer Res Clin Oncol (1987) 0.87
Infection of Epstein-Barr virus-transformed lymphoblastoid B cells by the human immunodeficiency virus: evidence for a persistent and productive infection leading to B cell phenotypic changes. Eur J Immunol (1990) 0.87
Combination chemotherapy with navelbine and continuous infusion of 5-fluorouracil in metastatic, chemotherapy refractory breast cancer. Ann Oncol (2000) 0.87
Association of p53 gene and protein alterations with metastases in colorectal cancer. Am J Surg Pathol (1995) 0.87
Functional implication for the topographical relationship between MHC class II and the low-affinity IgE receptor: occupancy of CD23 prevents B lymphocytes from stimulating allogeneic mixed lymphocyte responses. Eur J Immunol (1990) 0.87
B-cell activation during HIV-1 infection. III. Down-regulating effect of mitogens. AIDS (1991) 0.87
Head and neck cancer and ageing: a retrospective study in 438 patients. J Laryngol Otol (1990) 0.86
A clinical-pharmacological evaluation of percutaneous isolated hepatic infusion of doxorubicin in patients with unresectable liver tumors. Oncol Res (1999) 0.86
Primary lymphoblastic lymphoma of the breast. Clin Oncol (1982) 0.86
Prospective analysis of the information level of Italian cancer patients. Eur J Cancer (1995) 0.86
Pathology and ploidy in the prognosis of gastric cancer with no extranodal metastasis. Cancer (1994) 0.86
HTLV-I and HTLV-II infections among HIV-1 seropositive patients in Sao Paulo, Brazil. Eur J Epidemiol (1994) 0.85
Molecular profile of Epstein-Barr virus in human immunodeficiency virus type 1-related lymphadenopathies and lymphomas. Blood (1997) 0.85
Circulating and disseminated tumor cells in the clinical management of breast cancer patients: unanswered questions. Oncology (2009) 0.85
Spontaneous lymphomas in SJL/J-(v+) mice: ecotropic and dualtropic virus expression in normal and lymphomatous tissues. J Natl Cancer Inst (1981) 0.85
Occasional loss of constitutive heterozygosity at 11p15.5 and imprinting relaxation of the IGFII maternal allele in hepatoblastoma. J Cancer Res Clin Oncol (1994) 0.85
The angiogenic switch: implications in the regulation of tumor dormancy. Curr Mol Med (2009) 0.85
AMPK inhibition enhances apoptosis in MLL-rearranged pediatric B-acute lymphoblastic leukemia cells. Leukemia (2012) 0.85