Published in Br J Cancer on November 17, 2003
Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1. Proc Natl Acad Sci U S A (2012) 1.80
Renal cell carcinoma. Cancer Biomark (2010) 1.56
Comparative mRNA and microRNA expression profiling of three genitourinary cancers reveals common hallmarks and cancer-specific molecular events. PLoS One (2011) 1.15
Nucleostemin mRNA is expressed in both normal and malignant renal tissues. Br J Cancer (2006) 1.07
Combined expression of caveolin-1 and an activated AKT/mTOR pathway predicts reduced disease-free survival in clinically confined renal cell carcinoma. Br J Cancer (2008) 1.06
Co-regulation of cell polarization and migration by caveolar proteins PTRF/Cavin-1 and caveolin-1. PLoS One (2012) 0.94
HK-2 human renal proximal tubule cells as a model for G protein-coupled receptor kinase type 4-mediated dopamine 1 receptor uncoupling. Hypertension (2010) 0.93
Caveolin-1 promotes pancreatic cancer cell differentiation and restores membranous E-cadherin via suppression of the epithelial-mesenchymal transition. Cell Cycle (2011) 0.87
Caveolin 1 protein expression in renal cell carcinoma predicts survival. BMC Urol (2011) 0.85
Value of caveolin-1 in cancer progression and prognosis: Emphasis on cancer-associated fibroblasts, human cancer cells and mechanism of caveolin-1 expression (Review). Oncol Lett (2014) 0.84
Caveolin-1 in renal cell carcinoma promotes tumour cell invasion, and in co-operation with pERK predicts metastases in patients with clinically confined disease. J Transl Med (2013) 0.84
Caveolin-1 as a promoter of tumour spreading: when, how, where and why. J Cell Mol Med (2013) 0.84
Involvement of Caveolin-1 in repair of DNA damage through both homologous recombination and non-homologous end joining. PLoS One (2010) 0.83
Caveolin-1 expression in benign and malignant lesions of the breast. World J Surg Oncol (2007) 0.81
Phospho-4e-BP1 and eIF4E overexpression synergistically drives disease progression in clinically confined clear cell renal cell carcinoma. Am J Cancer Res (2015) 0.80
Combined cell surface carbonic anhydrase 9 and CD147 antigens enable high-efficiency capture of circulating tumor cells in clear cell renal cell carcinoma patients. Oncotarget (2016) 0.78
The different functions and clinical significances of caveolin-1 in human adenocarcinoma and squamous cell carcinoma. Onco Targets Ther (2017) 0.75
Genetic Variants in Caveolin-1 and RhoA/ROCK1 Are Associated with Clear Cell Renal Cell Carcinoma Risk in a Chinese Population. PLoS One (2015) 0.75
Prognostic value of caveolin-1 in genitourinary cancer: a meta-analysis. Int J Clin Exp Med (2015) 0.75
Prognostic significance of morphologic parameters in renal cell carcinoma. Am J Surg Pathol (1982) 8.47
The Heidelberg classification of renal cell tumours. J Pathol (1997) 5.36
Caveolae: from cell biology to animal physiology. Pharmacol Rev (2002) 4.45
Tyrosine phosphorylation of a 22-kDa protein is correlated with transformation by Rous sarcoma virus. J Biol Chem (1989) 2.86
Role of plasmalemmal caveolae in signal transduction. Am J Physiol (1998) 2.77
Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells. Oncogene (1998) 2.59
A role for caveolin and the urokinase receptor in integrin-mediated adhesion and signaling. J Cell Biol (1999) 2.46
Follow-up guidelines for nonmetastatic renal cell carcinoma based on the occurrence of metastases after radical nephrectomy. BJU Int (1999) 2.19
Caveolin-1 expression in clinically confined human prostate cancer: a novel prognostic marker. Cancer Res (1999) 1.95
Up-regulated caveolin-1 accentuates the metastasis capability of lung adenocarcinoma by inducing filopodia formation. Am J Pathol (2002) 1.78
Risk factors for adult renal cell carcinoma: a systematic review and implications for prevention. BJU Int (2000) 1.67
Secreted caveolin-1 stimulates cell survival/clonal growth and contributes to metastasis in androgen-insensitive prostate cancer. Cancer Res (2001) 1.66
Overexpression of caveolin-1 in esophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage. Cancer (2002) 1.54
Analysis of the prognostic implications of different tumour margin types in renal cell carcinoma. Histopathology (2003) 1.50
The urokinase-type plasminogen activator receptor, a GPI-linked protein, is localized in caveolae. J Cell Biol (1995) 1.47
Genes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers. FEBS Lett (1998) 1.47
Elevated expression of caveolin-1 in adenocarcinoma of the colon. Am J Clin Pathol (2001) 1.41
Reduction of caveolin 1 gene expression in lung carcinoma cell lines. Biochem Biophys Res Commun (1999) 1.34
Caveolin-1 expression enhances endothelial capillary tubule formation. J Biol Chem (2001) 1.30
MMP-2 colocalizes with caveolae on the surface of endothelial cells. Exp Cell Res (2001) 1.28
Impact of caveolin-1 expression on prognosis of pancreatic ductal adenocarcinoma. Br J Cancer (2002) 1.19
Loss of heterozygosity on the long arm of human chromosome 7 in sporadic renal cell carcinomas. Oncogene (1997) 1.17
Disruption of the caveolin-1 gene impairs renal calcium reabsorption and leads to hypercalciuria and urolithiasis. Am J Pathol (2003) 1.16
Microscopic vascular invasion is the most relevant prognosticator after radical nephrectomy for clinically nonmetastatic renal cell carcinoma. J Urol (1997) 1.15
Contribution of grade, vascular invasion and age to outcome in clinically localized renal cell carcinoma. BJU Int (2002) 1.07
Downmodulation of caveolin-1 expression in human ovarian carcinoma is directly related to alpha-folate receptor overexpression. Oncogene (2000) 1.04
A novel p64-related Cl- channel: subcellular distribution and nephron segment-specific expression. Am J Physiol (1999) 1.03
Significance of angiogenesis and microvascular invasion in renal cell carcinoma. Pathol Oncol Res (2002) 1.00
Immunohistochemical characterization of the intracellular pool of water channel aquaporin-2 in the rat kidney. Anat Sci Int (2002) 0.93
Downregulation and altered spatial pattern of caveolin-1 in chronic plaque psoriasis. Br J Dermatol (2002) 0.87
Kidney morcellation in laparoscopic nephrectomy for tumor: recommendations for specimen sampling and pathologic tumor staging. Am J Surg Pathol (2001) 0.80
Elastography in the detection of prostatic cancer. Clin Radiol (2002) 2.55
Analysis of the prognostic implications of different tumour margin types in renal cell carcinoma. Histopathology (2003) 1.50
Caveolin-1 expression and caveolae biogenesis during cell transdifferentiation in lung alveolar epithelial primary cultures. Biochem Biophys Res Commun (1999) 1.28
A UK-based investigation of inter- and intra-observer reproducibility of Gleason grading of prostatic biopsies. Histopathology (2006) 1.27
Caveolin and its cellular and subcellular immunolocalisation in lung alveolar epithelium: implications for alveolar epithelial type I cell function. Cell Tissue Res (1999) 1.15
Combined expression of caveolin-1 and an activated AKT/mTOR pathway predicts reduced disease-free survival in clinically confined renal cell carcinoma. Br J Cancer (2008) 1.06
Improved gas chromatographic assay for the simultaneous determination of nitroglycerin and its mono- and dinitrate metabolites. J Chromatogr (1992) 0.96
Synthesis, anti-human immunodeficiency virus activity and esterase lability of some novel carboxylic ester-modified phosphoramidate derivatives of stavudine (d4T). Antivir Chem Chemother (1998) 0.96
Best Practice No 180. Nephrectomy for renal tumour; dissection guide and dataset. J Clin Pathol (2005) 0.90
Downregulation and altered spatial pattern of caveolin-1 in chronic plaque psoriasis. Br J Dermatol (2002) 0.87
Examination of the biophysical interaction between plasmid DNA and the polycations, polylysine and polyornithine, as a basis for their differential gene transfection in-vitro. Int J Pharm (2000) 0.86
Polylysine and polyornithine gene transfer complexes: a study of complex stability and cellular uptake as a basis for their differential in-vitro transfection efficiency. J Drug Target (2002) 0.85
Physical stability and in-vitro gene expression efficiency of nebulised lipid-peptide-DNA complexes. Int J Pharm (2000) 0.85
The possible relationship between hepatic drug metabolism and ketoconazole enhancement of cyclosporine nephrotoxicity. Transplantation (1985) 0.84
Aberrant caveolin-1 expression in psoriasis: a signalling hypothesis. IUBMB Life (2000) 0.83
Transport of phosphatidylcholine in MDR3-negative epithelial cell lines via drug-induced MDR1 P-glycoprotein. Biochem Biophys Res Commun (1999) 0.83
The inhibition of phagocytosis of respirable microspheres by alveolar and peritoneal macrophages. Int J Pharm (2002) 0.82
In-vivo effects of itraconazole on hepatic mixed-function oxidase. J Antimicrob Chemother (1988) 0.81
Interpretation and utilization of effect and concentration data collected in an in vivo pharmacokinetic and in vitro pharmacodynamic study. Pharm Res (1993) 0.80
Gene expression in an intact ex-vivo skin tissue model following percutaneous delivery of cationic liposome-plasmid DNA complexes. Int J Pharm (2000) 0.80
Lung surfactant phospholipids inhibit the uptake of respirable microspheres by the alveolar macrophage NR8383. J Pharm Pharmacol (2002) 0.78
The effect of fatty acids and analogues upon intracellular levels of doxorubicin in cells displaying P-glycoprotein mediated multidrug resistance. J Drug Target (2000) 0.78
Pharmacological activity of the dinitrate metabolites of nitroglycerin following their oral administration to healthy volunteers. Br J Clin Pharmacol (1991) 0.77
Temporal dependence of ectopeptidase expression in alveolar epithelial cell culture: implications for study of peptide absorption. Int J Pharm (1999) 0.77
Interaction of cyclosporin and itraconazole. Lancet (1987) 0.77
Caveolae and the caveolins in human disease. Adv Drug Deliv Rev (2001) 0.77
Pharmacokinetic studies of the nitroglycerin metabolites, 1,2- and 1,3- glyceryl dinitrates, in the rat. Biopharm Drug Dispos (1991) 0.77
In vitro assessment of cephaloridine nephrotoxicity: comparison of renal cortical slice and renal tubule fragment techniques. J Pharmacol Methods (1988) 0.75
Percutaneous penetration kinetics of nitroglycerin and its dinitrate metabolites across hairless mouse skin in vitro. Pharm Res (1991) 0.75
Comparison of vasodilatory responses to nitroglycerin and its dinitrate metabolites in human veins. Clin Pharmacol Ther (1992) 0.75
Statistical modelling of the formulation variables in non-viral gene delivery systems. J Drug Target (2001) 0.75
Paraganglion of the prostate gland: an uncommon mimic of prostate cancer in needle biopsies. Histopathology (2005) 0.75
Microcalorimetry does not predict the cellular phagocytosis of latex microspheres. Int J Pharm (2000) 0.75