Published in J Biomech on December 01, 2003
Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives. Physiol Rev (2011) 5.51
Complex hemodynamics at the apex of an arterial bifurcation induces vascular remodeling resembling cerebral aneurysm initiation. Stroke (2007) 2.58
Hemodynamic-morphologic discriminants for intracranial aneurysm rupture. Stroke (2010) 2.12
Intracranial aneurysms: links among inflammation, hemodynamics and vascular remodeling. Neurol Res (2006) 1.81
Alteration of intra-aneurysmal hemodynamics for flow diversion using enterprise and vision stents. World Neurosurg (2011) 1.63
Flow shear stress and atherosclerosis: a matter of site specificity. Antioxid Redox Signal (2011) 1.39
Quantification of hemodynamic changes induced by virtual placement of multiple stents across a wide-necked basilar trunk aneurysm. Neurosurgery (2007) 1.32
Endothelial microRNAs and atherosclerosis. Curr Atheroscler Rep (2013) 1.17
Mechanisms of induction of endothelial cell E-selectin expression by smooth muscle cells and its inhibition by shear stress. Blood (2007) 1.13
MicroRNA Regulation of Atherosclerosis. Circ Res (2016) 1.10
Hemodynamically driven stent strut design. Ann Biomed Eng (2009) 1.07
Endothelial cell layer subjected to impinging flow mimicking the apex of an arterial bifurcation. Ann Biomed Eng (2008) 1.00
Molecular alterations associated with aneurysmal remodeling are localized in the high hemodynamic stress region of a created carotid bifurcation. Neurosurgery (2009) 0.96
The roles of platelet GPIIb/IIIa and alphavbeta3 integrins during HeLa cells adhesion, migration, and invasion to monolayer endothelium under static and dynamic shear flow. J Biomed Biotechnol (2009) 0.95
Thrombosis in the uremic milieu--emerging role of "thrombolome". Semin Dial (2014) 0.86
Microvascular endothelial cells migrate upstream and align against the shear stress field created by impinging flow. Biophys J (2014) 0.84
A comparative review of the hemodynamics and pathogenesis of cerebral and abdominal aortic aneurysms: lessons to learn from each other. J Cerebrovasc Endovasc Neurosurg (2014) 0.79
Intima modifier locus 2 controls endothelial cell activation and vascular permeability. Physiol Genomics (2014) 0.77
Specificity in the participation of connexin proteins in flow-induced endothelial gap junction communication. Pflugers Arch (2013) 0.75
Endothelial injury preceding intracranial aneurysm formation in rabbits. West Indian Med J (2014) 0.75
Fluid Shear Stress and Fibroblast Growth Factor-2 Increase Endothelial Cell-Associated Vitronectin. Appl Bionics Biomech (2017) 0.75
Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives. Physiol Rev (2011) 5.51
Visualizing the mechanical activation of Src. Nature (2005) 4.63
An extracellular matrix microarray for probing cellular differentiation. Nat Methods (2005) 4.35
Molecular basis of the effects of shear stress on vascular endothelial cells. J Biomech (2005) 3.77
Stem cell fate dictated solely by altered nanotube dimension. Proc Natl Acad Sci U S A (2009) 3.73
Role of integrins in endothelial mechanosensing of shear stress. Circ Res (2002) 2.85
Cooperative effects of Rho and mechanical stretch on stress fiber organization. Proc Natl Acad Sci U S A (2005) 2.78
Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression. EMBO J (2002) 2.46
A positive feedback mechanism governs the polarity and motion of motile cilia. Nature (2007) 2.44
Flow-Dependent Regulation of Kruppel-Like Factor 2 Is Mediated by MicroRNA-92a. Circulation (2011) 2.29
Effects of cell tension on the small GTPase Rac. J Cell Biol (2002) 2.24
Fluorescence proteins, live-cell imaging, and mechanobiology: seeing is believing. Annu Rev Biomed Eng (2008) 2.16
Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression. Mol Cell (2003) 2.09
Biochemistry and biomechanics of cell motility. Annu Rev Biomed Eng (2005) 2.08
Regulation of vascular smooth muscle cell turnover by endothelial cell-secreted microRNA-126: role of shear stress. Circ Res (2013) 2.04
Molecular basis of the effects of mechanical stretch on vascular smooth muscle cells. J Biomech (2006) 2.02
The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells. Proc Natl Acad Sci U S A (2002) 2.01
Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors. Proc Natl Acad Sci U S A (2008) 1.97
Klotho is a target gene of PPAR-gamma. Kidney Int (2008) 1.96
MicroRNA-19a mediates the suppressive effect of laminar flow on cyclin D1 expression in human umbilical vein endothelial cells. Proc Natl Acad Sci U S A (2010) 1.80
Live Cells Exert 3-Dimensional Traction Forces on Their Substrata. Cell Mol Bioeng (2009) 1.80
Rho mediates the shear-enhancement of endothelial cell migration and traction force generation. Biophys J (2004) 1.77
MicroRNA-21 targets peroxisome proliferators-activated receptor-alpha in an autoregulatory loop to modulate flow-induced endothelial inflammation. Proc Natl Acad Sci U S A (2011) 1.77
Combinatorial signaling microenvironments for studying stem cell fate. Stem Cells Dev (2008) 1.76
Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow. Proc Natl Acad Sci U S A (2009) 1.74
Role of microRNA-23b in flow-regulation of Rb phosphorylation and endothelial cell growth. Proc Natl Acad Sci U S A (2010) 1.73
Shear stress, SIRT1, and vascular homeostasis. Proc Natl Acad Sci U S A (2010) 1.68
Vascular endothelial cell growth-activated XBP1 splicing in endothelial cells is crucial for angiogenesis. Circulation (2013) 1.60
Shear stress regulation of Krüppel-like factor 2 expression is flow pattern-specific. Biochem Biophys Res Commun (2006) 1.57
Regulation of endothelial cell cycle by laminar versus oscillatory flow: distinct modes of interactions of AMP-activated protein kinase and Akt pathways. Circ Res (2007) 1.48
Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice. Proc Natl Acad Sci U S A (2008) 1.48
Defining long-term maintenance conditions of human embryonic stem cells with arrayed cellular microenvironment technology. Stem Cells Dev (2009) 1.46
Shear stress increases ICAM-1 and decreases VCAM-1 and E-selectin expressions induced by tumor necrosis factor-[alpha] in endothelial cells. Arterioscler Thromb Vasc Biol (2003) 1.45
Suppression of pro-inflammatory adhesion molecules by PPAR-delta in human vascular endothelial cells. Arterioscler Thromb Vasc Biol (2007) 1.45
microRNA: a master regulator of cellular processes for bioengineering systems. Annu Rev Biomed Eng (2010) 1.44
Long-term human pluripotent stem cell self-renewal on synthetic polymer surfaces. Biomaterials (2010) 1.42
Integrins regulate VE-cadherin and catenins: dependence of this regulation on Src, but not on Ras. Proc Natl Acad Sci U S A (2006) 1.39
Effects of flow patterns on the localization and expression of VE-cadherin at vascular endothelial cell junctions: in vivo and in vitro investigations. J Vasc Res (2005) 1.37
Genomic analysis of smooth muscle cells in 3-dimensional collagen matrix. FASEB J (2002) 1.33
Integrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticity. Proc Natl Acad Sci U S A (2011) 1.31
Flow activation of AMP-activated protein kinase in vascular endothelium leads to Krüppel-like factor 2 expression. Arterioscler Thromb Vasc Biol (2009) 1.30
The spatiotemporal pattern of Src activation at lipid rafts revealed by diffusion-corrected FRET imaging. PLoS Comput Biol (2008) 1.27
Regulation of stretch-induced JNK activation by stress fiber orientation. Cell Signal (2006) 1.27
Shear stress inhibits adhesion molecule expression in vascular endothelial cells induced by coculture with smooth muscle cells. Blood (2002) 1.27
Vascular endothelial responses to altered shear stress: pathologic implications for atherosclerosis. Ann Med (2009) 1.26
Phosphatidylinositol 3-kinase/Akt pathway is involved in transforming growth factor-beta1-induced phenotypic modulation of 10T1/2 cells to smooth muscle cells. Cell Signal (2005) 1.25
Differential regulation of Rho GTPases by beta1 and beta3 integrins: the role of an extracellular domain of integrin in intracellular signaling. J Cell Sci (2002) 1.24
In vivo knee moments and shear after total knee arthroplasty. J Biomech (2007) 1.24
Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad. Proc Natl Acad Sci U S A (2008) 1.23
Roles of cell confluency and fluid shear in 3-dimensional intracellular forces in endothelial cells. Proc Natl Acad Sci U S A (2012) 1.22
Laminar flow activates peroxisome proliferator-activated receptor-gamma in vascular endothelial cells. Circulation (2004) 1.22
Modulation of notch-1 signaling alleviates vascular endothelial growth factor-mediated diabetic nephropathy. Diabetes (2010) 1.21
Shear stress activation of SREBP1 in endothelial cells is mediated by integrins. Arterioscler Thromb Vasc Biol (2002) 1.20
Predicting factors in the last week of survival in elderly patients with terminal cancer: a prospective study in southern Taiwan. J Formos Med Assoc (2009) 1.20
Mechanical stimuli and nutrients regulate rapamycin-sensitive signaling through distinct mechanisms in skeletal muscle. J Cell Biochem (2006) 1.20
Interplay between integrins and FLK-1 in shear stress-induced signaling. Am J Physiol Cell Physiol (2002) 1.17
Operative treatment of midclavicular fractures in 62 elderly patients: knowles pin versus plate. Orthopedics (2007) 1.14
Anisotropic rheology and directional mechanotransduction in vascular endothelial cells. Proc Natl Acad Sci U S A (2008) 1.14
Mechanisms of induction of endothelial cell E-selectin expression by smooth muscle cells and its inhibition by shear stress. Blood (2007) 1.13
Oxidative stress is involved in the development of experimental abdominal aortic aneurysm: a study of the transcription profile with complementary DNA microarray. J Vasc Surg (2002) 1.12
Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow. Proc Natl Acad Sci U S A (2012) 1.11
Rho-ROCK-LIMK-cofilin pathway regulates shear stress activation of sterol regulatory element binding proteins. Circ Res (2003) 1.11
Synergistic roles of platelet-derived growth factor-BB and interleukin-1beta in phenotypic modulation of human aortic smooth muscle cells. Proc Natl Acad Sci U S A (2006) 1.11
Synergism of biochemical and mechanical stimuli in the differentiation of human placenta-derived multipotent cells into endothelial cells. J Biomech (2008) 1.09
Directional shear flow and Rho activation prevent the endothelial cell apoptosis induced by micropatterned anisotropic geometry. Proc Natl Acad Sci U S A (2007) 1.08
Calcium phosphate-bearing matrices induce osteogenic differentiation of stem cells through adenosine signaling. Proc Natl Acad Sci U S A (2014) 1.08
Role of focal adhesion kinase Ser-732 phosphorylation in centrosome function during mitosis. J Biol Chem (2009) 1.07
Detection of focal adhesion kinase activation at membrane microdomains by fluorescence resonance energy transfer. Nat Commun (2011) 1.06
Rate sensitivity of shear-induced changes in the lateral diffusion of endothelial cell membrane lipids: a role for membrane perturbation in shear-induced MAPK activation. FASEB J (2001) 1.05
Rho-GDP dissociation inhibitor alpha downregulated by low shear stress promotes vascular smooth muscle cell migration and apoptosis: a proteomic analysis. Cardiovasc Res (2008) 1.05
Roles of microtubule dynamics and small GTPase Rac in endothelial cell migration and lamellipodium formation under flow. J Vasc Res (2003) 1.04