Published in Biochemistry on December 09, 2003
Calcium-dependent and -independent interactions of the S100 protein family. Biochem J (2006) 2.62
S100A4-induced cell motility and metastasis is restricted by the Wnt/β-catenin pathway inhibitor calcimycin in colon cancer cells. Mol Biol Cell (2011) 1.71
Myosin-IIA heavy-chain phosphorylation regulates the motility of MDA-MB-231 carcinoma cells. Mol Biol Cell (2007) 1.64
MicroRNA let-7f inhibits tumor invasion and metastasis by targeting MYH9 in human gastric cancer. PLoS One (2011) 1.51
Multiple myosin II heavy chain kinases: roles in filament assembly control and proper cytokinesis in Dictyostelium. Mol Biol Cell (2005) 1.48
TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation. J Mol Biol (2008) 1.32
Nonmuscle myosin-2: mix and match. Cell Mol Life Sci (2012) 1.30
Protein kinase Cgamma regulates myosin IIB phosphorylation, cellular localization, and filament assembly. Mol Biol Cell (2006) 1.22
S100A4 regulates macrophage chemotaxis. Mol Biol Cell (2010) 1.19
Two regions of the tail are necessary for the isoform-specific functions of nonmuscle myosin IIB. Mol Biol Cell (2007) 1.14
CSF-1 receptor signaling in myeloid cells. Cold Spring Harb Perspect Biol (2014) 1.10
Structure of Ca2+-bound S100A4 and its interaction with peptides derived from nonmuscle myosin-IIA. Biochemistry (2008) 1.10
A biosensor of S100A4 metastasis factor activation: inhibitor screening and cellular activation dynamics. Biochemistry (2007) 1.10
S100A4 (Mts1) gene overexpression is associated with invasion and metastasis of papillary thyroid carcinoma. Br J Cancer (2005) 1.05
S100A4 and bone morphogenetic protein-2 codependently induce vascular smooth muscle cell migration via phospho-extracellular signal-regulated kinase and chloride intracellular channel 4. Circ Res (2009) 1.04
Phenothiazines inhibit S100A4 function by inducing protein oligomerization. Proc Natl Acad Sci U S A (2010) 1.03
Interleukin-7 stimulates secretion of S100A4 by activating the JAK/STAT signaling pathway in human articular chondrocytes. Arthritis Rheum (2009) 1.03
Expression of the calcium-binding protein S100A4 is markedly up-regulated by osmotic stress and is involved in the renal osmoadaptive response. J Biol Chem (2007) 0.99
The heavy chain has its day: regulation of myosin-II assembly. Bioarchitecture (2014) 0.94
A global, myosin light chain kinase-dependent increase in myosin II contractility accompanies the metaphase-anaphase transition in sea urchin eggs. Mol Biol Cell (2006) 0.93
Crystal structure of the S100A4-nonmuscle myosin IIA tail fragment complex reveals an asymmetric target binding mechanism. Proc Natl Acad Sci U S A (2012) 0.93
Coupling S100A4 to Rhotekin alters Rho signaling output in breast cancer cells. Oncogene (2012) 0.91
Asymmetric mode of Ca²⁺-S100A4 interaction with nonmuscle myosin IIA generates nanomolar affinity required for filament remodeling. Structure (2012) 0.90
Analysis of the role of Ser1/Ser2/Thr9 phosphorylation on myosin II assembly and function in live cells. BMC Cell Biol (2011) 0.90
Mechanism of the Ca²+-dependent interaction between S100A4 and tail fragments of nonmuscle myosin heavy chain IIA. J Mol Biol (2010) 0.89
S100P dissociates myosin IIA filaments and focal adhesion sites to reduce cell adhesion and enhance cell migration. J Biol Chem (2012) 0.87
S100 proteins as diagnostic and prognostic markers in colorectal and hepatocellular carcinoma. Hepat Mon (2012) 0.87
Overexpression of S100A4 as a biomarker of metastasis and recurrence in oral squamous cell carcinoma. J Appl Oral Sci (2014) 0.86
Cysteine 81 is critical for the interaction of S100A4 and myosin-IIA. Biochemistry (2011) 0.85
Rap1 activation in collagen phagocytosis is dependent on nonmuscle myosin II-A. Mol Biol Cell (2008) 0.83
Myosin II isoform co-assembly and differential regulation in mammalian systems. Exp Cell Res (2015) 0.82
Depletion of the aryl hydrocarbon receptor in MDA-MB-231 human breast cancer cells altered the expression of genes in key regulatory pathways of cancer. PLoS One (2014) 0.81
Two functional S100A4 monomers are necessary for regulating nonmuscle myosin-IIA and HCT116 cell invasion. Biochemistry (2011) 0.81
Structure of the S100A4/myosin-IIA complex. BMC Struct Biol (2013) 0.80
Life without double-headed non-muscle myosin II motor proteins. Front Chem (2014) 0.78
Small interfering RNA targeting S100A4 sensitizes non-small-cell lung cancer cells (A549) to radiation treatment. Onco Targets Ther (2016) 0.77
MAL overexpression leads to disturbed expression of genes that influence cytoskeletal organization and differentiation of Schwann cells. ASN Neuro (2014) 0.77
Collagen remodeling by phagocytosis is determined by collagen substrate topology and calcium-dependent interactions of gelsolin with nonmuscle myosin IIA in cell adhesions. Mol Biol Cell (2013) 0.77
Identification of calcium-independent and calcium-enhanced binding between S100B and the dopamine D2 receptor. Biochemistry (2011) 0.77
S100A4 downregulates filopodia formation through increased dynamic instability. Cell Adh Migr (2011) 0.76
A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc Natl Acad Sci U S A (2005) 6.61
Periodic lamellipodial contractions correlate with rearward actin waves. Cell (2004) 6.46
microRNA modulation of circadian-clock period and entrainment. Neuron (2007) 4.49
An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP. Proc Natl Acad Sci U S A (2008) 3.98
S100A4, a mediator of metastasis. J Biol Chem (2005) 2.68
The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors. J Cell Biol (2006) 2.59
An activity-induced microRNA controls dendritic spine formation by regulating Rac1-PAK signaling. Mol Cell Neurosci (2009) 2.28
Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer. J Cell Sci (2011) 2.00
Structural genomics: a pipeline for providing structures for the biologist. Protein Sci (2002) 1.91
Cell type-specific regulation of RhoA activity during cytokinesis. J Biol Chem (2004) 1.76
Regulation of myosin-IIA assembly and Mts1 binding by heavy chain phosphorylation. Biochemistry (2005) 1.73
Integrin alpha6beta4 controls the expression of genes associated with cell motility, invasion, and metastasis, including S100A4/metastasin. J Biol Chem (2008) 1.67
Increase in production of matrix metalloproteinase 13 by human articular chondrocytes due to stimulation with S100A4: Role of the receptor for advanced glycation end products. Arthritis Rheum (2006) 1.65
Myosin-IIA heavy-chain phosphorylation regulates the motility of MDA-MB-231 carcinoma cells. Mol Biol Cell (2007) 1.64
Visual snapshots of intracellular kinase activity at the onset of mitosis. Chem Biol (2007) 1.63
The S100A4 metastasis factor regulates cellular motility via a direct interaction with myosin-IIA. Cancer Res (2006) 1.61
Roles of Rho-associated kinase and myosin light chain kinase in morphological and migratory defects of focal adhesion kinase-null cells. J Biol Chem (2002) 1.51
Differential enhancement of breast cancer cell motility and metastasis by helical and kinase domain mutations of class IA phosphoinositide 3-kinase. Cancer Res (2009) 1.45
G protein-coupled receptor-mediated activation of p110β by Gβγ is required for cellular transformation and invasiveness. Sci Signal (2012) 1.38
TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation. J Mol Biol (2008) 1.32
KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription. EMBO J (2011) 1.27
A collaborative database and computational models for tuberculosis drug discovery. Mol Biosyst (2010) 1.24
Analysis and hit filtering of a very large library of compounds screened against Mycobacterium tuberculosis. Mol Biosyst (2010) 1.21
S100A4 regulates macrophage chemotaxis. Mol Biol Cell (2010) 1.19
Solution structure of human Mts1 (S100A4) as determined by NMR spectroscopy. Biochemistry (2002) 1.11
Structure of Ca2+-bound S100A4 and its interaction with peptides derived from nonmuscle myosin-IIA. Biochemistry (2008) 1.10
A biosensor of S100A4 metastasis factor activation: inhibitor screening and cellular activation dynamics. Biochemistry (2007) 1.10
Myosin II isoform switching mediates invasiveness after TGF-β-induced epithelial-mesenchymal transition. Proc Natl Acad Sci U S A (2011) 1.07
Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs). Proc Natl Acad Sci U S A (2013) 1.06
Phenothiazines inhibit S100A4 function by inducing protein oligomerization. Proc Natl Acad Sci U S A (2010) 1.03
The N-terminus of the long MLCK induces a disruption in normal spindle morphology and metaphase arrest. J Cell Sci (2004) 0.97
Direct inhibition of myosin II effectively blocks glioma invasion in the presence of multiple motogens. Mol Biol Cell (2012) 0.97
Real time visualization of protein kinase activity in living cells. J Biol Chem (2002) 0.95
The heavy chain has its day: regulation of myosin-II assembly. Bioarchitecture (2014) 0.94
A global, myosin light chain kinase-dependent increase in myosin II contractility accompanies the metaphase-anaphase transition in sea urchin eggs. Mol Biol Cell (2006) 0.93
Wiskott-Aldrich syndrome protein regulates leukocyte-dependent breast cancer metastasis. Cell Rep (2013) 0.92
The suppression of myosin light chain (MLC) phosphorylation during the response to lipopolysaccharide (LPS): beneficial or detrimental to endothelial barrier? J Cell Physiol (2011) 0.92
Cysteine biosynthetic enzymes are the pieces of a metabolic energy pump. Biochemistry (2002) 0.87
Cysteine 81 is critical for the interaction of S100A4 and myosin-IIA. Biochemistry (2011) 0.85
Rap1 activation in collagen phagocytosis is dependent on nonmuscle myosin II-A. Mol Biol Cell (2008) 0.83
High-throughput expression, purification, and characterization of recombinant Caenorhabditis elegans proteins. Biochem Biophys Res Commun (2003) 0.81
Two functional S100A4 monomers are necessary for regulating nonmuscle myosin-IIA and HCT116 cell invasion. Biochemistry (2011) 0.81
Structure of the S100A4/myosin-IIA complex. BMC Struct Biol (2013) 0.80
Calibration of the continuous glucose monitoring system for transient glucose monitoring. Diabetes Technol Ther (2007) 0.78
The long myosin light chain kinase is differentially phosphorylated during interphase and mitosis. Exp Cell Res (2004) 0.78
Identification of the Rab5 binding site in p110β: assays for PI3Kβ binding to Rab5. Methods Mol Biol (2015) 0.76
Genesis of femtosecond-induced nanostructures on solid surfaces. Appl Opt (2014) 0.75