Published in Trends Genet on December 01, 2003
A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins. BMC Genomics (2004) 1.34
Insight into invertebrate defensin mechanism of action: oyster defensins inhibit peptidoglycan biosynthesis by binding to lipid II. J Biol Chem (2010) 1.19
High alpha-defensin levels in patients with systemic lupus erythematosus. Immunology (2009) 0.96
Selection on an antimicrobial peptide defensin in ants. J Mol Evol (2008) 0.88
On the evolution of invertebrate defensins. Trends Genet (2005) 0.88
Evolutionary genetics of insect innate immunity. Brief Funct Genomics (2015) 0.85
The Antimicrobial Defense of the Pacific Oyster, Crassostrea gigas. How Diversity may Compensate for Scarcity in the Regulation of Resident/Pathogenic Microflora. Front Microbiol (2012) 0.82
Enhanced synonymous site divergence in positively selected vertebrate antimicrobial peptide genes. J Mol Evol (2005) 0.81
Evidence for myxobacterial origin of eukaryotic defensins. Immunogenetics (2007) 0.80
Comparative genomic study of arachnid immune systems indicates loss of beta-1,3-glucanase-related proteins and the immune deficiency pathway. J Evol Biol (2015) 0.80
The first report of a Pelecaniformes defensin cluster: characterization of β-defensin genes in the crested ibis based on BAC libraries. Sci Rep (2014) 0.80
Molecular characterization of antimicrobial peptide genes of the carpenter ant Camponotus floridanus. PLoS One (2012) 0.80
The fungal defensin family enlarged. Pharmaceuticals (Basel) (2014) 0.77
Expression of Immune-Related Genes of Ducks Infected with Avian Pathogenic Escherichia coli (APEC). Front Microbiol (2016) 0.76
Exon Shuffling and Origin of Scorpion Venom Biodiversity. Toxins (Basel) (2016) 0.75
Differentially-Expressed Genes Associated with Faster Growth of the Pacific Abalone, Haliotis discus hannai. Int J Mol Sci (2015) 0.75
Establishing a reference array for the CS-αβ superfamily of defensive peptides. BMC Res Notes (2016) 0.75
Identification of amino acid residues in the insect sodium channel critical for pyrethroid binding. Mol Pharmacol (2004) 1.57
Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor. Proc Natl Acad Sci U S A (2011) 1.36
Common features in the functional surface of scorpion beta-toxins and elements that confer specificity for insect and mammalian voltage-gated sodium channels. J Biol Chem (2004) 1.14
The differential preference of scorpion alpha-toxins for insect or mammalian sodium channels: implications for improved insect control. Toxicon (2006) 1.12
Convergent evolution of sodium ion selectivity in metazoan neuronal signaling. Cell Rep (2012) 1.07
Structure-function map of the receptor site for β-scorpion toxins in domain II of voltage-gated sodium channels. J Biol Chem (2011) 1.05
Molecular basis of the high insecticidal potency of scorpion alpha-toxins. J Biol Chem (2004) 1.04
Elucidation of the molecular basis of selective recognition uncovers the interaction site for the core domain of scorpion alpha-toxins on sodium channels. J Biol Chem (2011) 1.00
Mapping the interaction site for a β-scorpion toxin in the pore module of domain III of voltage-gated Na(+) channels. J Biol Chem (2012) 0.99
X-ray structure and mutagenesis of the scorpion depressant toxin LqhIT2 reveals key determinants crucial for activity and anti-insect selectivity. J Mol Biol (2006) 0.99
Neurotoxin localization to ectodermal gland cells uncovers an alternative mechanism of venom delivery in sea anemones. Proc Biol Sci (2011) 0.98
Dual role of cysteine 172 in redox regulation of ribulose 1,5-bisphosphate carboxylase/oxygenase activity and degradation. J Bacteriol (2003) 0.97
Positions under positive selection--key for selectivity and potency of scorpion alpha-toxins. Mol Biol Evol (2009) 0.97
Direct evidence that receptor site-4 of sodium channel gating modifiers is not dipped in the phospholipid bilayer of neuronal membranes. J Biol Chem (2006) 0.95
The unique pharmacology of the scorpion alpha-like toxin Lqh3 is associated with its flexible C-tail. FEBS J (2007) 0.94
Sea anemone toxins affecting voltage-gated sodium channels--molecular and evolutionary features. Toxicon (2009) 0.94
Conversion of a scorpion toxin agonist into an antagonist highlights an acidic residue involved in voltage sensor trapping during activation of neuronal Na+ channels. FASEB J (2004) 0.94
Design of a specific activator for skeletal muscle sodium channels uncovers channel architecture. J Biol Chem (2007) 0.93
Molecular requirements for recognition of brain voltage-gated sodium channels by scorpion alpha-toxins. J Biol Chem (2009) 0.92
Rubisco mutagenesis provides new insight into limitations on photosynthesis and growth in Synechocystis PCC6803. J Exp Bot (2011) 0.90
New insight on scorpion divergence inferred from comparative analysis of toxin structure, pharmacology and distribution. Toxicon (2003) 0.90
A spider toxin that induces a typical effect of scorpion alpha-toxins but competes with beta-toxins on binding to insect sodium channels. Biochemistry (2005) 0.89
The selectivity of scorpion alpha-toxins for sodium channel subtypes is determined by subtle variations at the interacting surface. Toxicon (2003) 0.89
Molecular analysis of the sea anemone toxin Av3 reveals selectivity to insects and demonstrates the heterogeneity of receptor site-3 on voltage-gated Na+ channels. Biochem J (2007) 0.89
Alterations in Rubisco activity and in stomatal behavior induce a daily rhythm in photosynthesis of aerial leaves in the amphibious-plant Nuphar lutea. Photosynth Res (2007) 0.89
Coupling between residues on S4 and S1 defines the voltage-sensor resting conformation in NaChBac. Biophys J (2010) 0.89
An 'Old World' scorpion beta-toxin that recognizes both insect and mammalian sodium channels. Eur J Biochem (2003) 0.87
Allosteric interactions among pyrethroid, brevetoxin, and scorpion toxin receptors on insect sodium channels raise an alternative approach for insect control. FEBS Lett (2003) 0.87
Concerted evolution of sea anemone neurotoxin genes is revealed through analysis of the Nematostella vectensis genome. Mol Biol Evol (2008) 0.87
Mutagenesis at two distinct phosphate-binding sites unravels their differential roles in regulation of Rubisco activation and catalysis. J Bacteriol (2005) 0.86
Intron retention as a posttranscriptional regulatory mechanism of neurotoxin expression at early life stages of the starlet anemone Nematostella vectensis. J Mol Biol (2008) 0.86
Dissection of the functional surface of an anti-insect excitatory toxin illuminates a putative "hot spot" common to all scorpion beta-toxins affecting Na+ channels. J Biol Chem (2003) 0.86
NMR analysis of interaction of LqhalphaIT scorpion toxin with a peptide corresponding to the D4/S3-S4 loop of insect para voltage-gated sodium channel. Biochemistry (2007) 0.85
Further enhancement of baculovirus insecticidal efficacy with scorpion toxins that interact cooperatively. FEBS Lett (2003) 0.85
Genetic polymorphism and expression of a highly potent scorpion depressant toxin enable refinement of the effects on insect Na channels and illuminate the key role of Asn-58. Biochemistry (2005) 0.84
Arthropod defensins illuminate the divergence of scorpion neurotoxins. J Pept Sci (2004) 0.83
Partial agonist and antagonist activities of a mutant scorpion beta-toxin on sodium channels. J Biol Chem (2010) 0.83
Expression and mutagenesis of the sea anemone toxin Av2 reveals key amino acid residues important for activity on voltage-gated sodium channels. Biochemistry (2006) 0.83
Mammalian skeletal muscle voltage-gated sodium channels are affected by scorpion depressant "insect-selective" toxins when preconditioned. Mol Pharmacol (2007) 0.82
Variations in receptor site-3 on rat brain and insect sodium channels highlighted by binding of a funnel-web spider delta-atracotoxin. Eur J Biochem (2002) 0.82
Miniaturization of scorpion beta-toxins uncovers a putative ancestral surface of interaction with voltage-gated sodium channels. J Biol Chem (2008) 0.81
Drosomycin, an innate immunity peptide of Drosophila melanogaster, interacts with the fly voltage-gated sodium channel. J Biol Chem (2009) 0.81
When positive selection of neurotoxin genes is missing. The riddle of the sea anemone Nematostella vectensis. FEBS J (2006) 0.80
Fusion and retrotransposition events in the evolution of the sea anemone Anemonia viridis neurotoxin genes. J Mol Evol (2009) 0.80
New measures of insecticidal efficacy and safety obtained with the 39K promoter of a recombinant baculovirus. FEBS Lett (2006) 0.79
Substitutions in the domain III voltage-sensing module enhance the sensitivity of an insect sodium channel to a scorpion beta-toxin. J Biol Chem (2011) 0.77
Direct evidence that scorpion α-toxins (site-3) modulate sodium channel inactivation by hindrance of voltage-sensor movements. PLoS One (2013) 0.75