PubRank

Alan D Cherrington

Author PubWeight™ 73.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover. J Clin Invest 2012 2.98
2 Novel PEGylated basal insulin LY2605541 has a preferential hepatic effect on glucose metabolism. Diabetes 2013 2.03
3 Regulation of hepatic glucose uptake and storage in vivo. Adv Nutr 2012 1.44
4 Insulin's direct effects on the liver dominate the control of hepatic glucose production. J Clin Invest 2006 1.43
5 Molecular characterization of insulin-mediated suppression of hepatic glucose production in vivo. Diabetes 2010 1.35
6 Effects of insulin on the metabolic control of hepatic gluconeogenesis in vivo. Diabetes 2009 1.23
7 Brain insulin action augments hepatic glycogen synthesis without suppressing glucose production or gluconeogenesis in dogs. J Clin Invest 2011 1.18
8 Rapid translocation of hepatic glucokinase in response to intraduodenal glucose infusion and changes in plasma glucose and insulin in conscious rats. Am J Physiol Gastrointest Liver Physiol 2003 1.15
9 Direct and indirect effects of insulin on glucose uptake and storage by the liver. Diabetes 2002 1.14
10 Current strategies for the inhibition of hepatic glucose production in type 2 diabetes. Front Biosci (Landmark Ed) 2009 1.07
11 Selective stimulation of G-6-Pase catalytic subunit but not G-6-P transporter gene expression by glucagon in vivo and cAMP in situ. Am J Physiol Endocrinol Metab 2004 1.02
12 Regulation of hepatic and peripheral glucose disposal. Best Pract Res Clin Endocrinol Metab 2003 1.02
13 Chronic consumption of a high-fat/high-fructose diet renders the liver incapable of net hepatic glucose uptake. Am J Physiol Endocrinol Metab 2010 1.02
14 Nonesterified fatty acids and hepatic glucose metabolism in the conscious dog. Diabetes 2004 1.01
15 A novel glucagon receptor antagonist, NNC 25-0926, blunts hepatic glucose production in the conscious dog. J Pharmacol Exp Ther 2007 1.00
16 Effects of free fatty acids on hepatic glycogenolysis and gluconeogenesis in conscious dogs. Am J Physiol Endocrinol Metab 2002 0.99
17 Intraportal GLP-1 infusion increases nonhepatic glucose utilization without changing pancreatic hormone levels. Am J Physiol Endocrinol Metab 2007 0.99
18 Insulin-induced hypoglycemia increases hepatic sensitivity to glucagon in dogs. J Clin Invest 2010 0.98
19 Insulin secretion-independent effects of GLP-1 on canine liver glucose metabolism do not involve portal vein GLP-1 receptors. Am J Physiol Gastrointest Liver Physiol 2005 0.97
20 Role of the hepatic sympathetic nerves in the regulation of net hepatic glucose uptake and the mediation of the portal glucose signal. Am J Physiol Endocrinol Metab 2005 0.97
21 Interaction between the central and peripheral effects of insulin in controlling hepatic glucose metabolism in the conscious dog. Diabetes 2012 0.97
22 A high-fat, high-fructose diet accelerates nutrient absorption and impairs net hepatic glucose uptake in response to a mixed meal in partially pancreatectomized dogs. J Nutr 2011 0.97
23 Effect of intraportal glucagon-like peptide-1 on glucose metabolism in conscious dogs. Am J Physiol Endocrinol Metab 2003 0.96
24 Effect of hepatic denervation on peripheral insulin sensitivity in conscious dogs. Am J Physiol Endocrinol Metab 2002 0.96
25 Evidence against a physiologic role for acute changes in CNS insulin action in the rapid regulation of hepatic glucose production. Cell Metab 2012 0.95
26 A physiological increase in the hepatic glycogen level does not affect the response of net hepatic glucose uptake to insulin. Am J Physiol Endocrinol Metab 2009 0.93
27 Effects of the nitric oxide donor SIN-1 on net hepatic glucose uptake in the conscious dog. Am J Physiol Endocrinol Metab 2007 0.91
28 Inhalation of insulin (Exubera) is associated with augmented disposal of portally infused glucose in dogs. Diabetes 2005 0.90
29 Glucagon as a critical factor in the pathology of diabetes. Diabetes 2011 0.90
30 Portal infusion of a selective serotonin reuptake inhibitor enhances hepatic glucose disposal in conscious dogs. Am J Physiol Endocrinol Metab 2004 0.89
31 Inclusion of low amounts of fructose with an intraduodenal glucose load markedly reduces postprandial hyperglycemia and hyperinsulinemia in the conscious dog. Diabetes 2002 0.89
32 Portal serotonin infusion and glucose disposal in conscious dogs. Diabetes 2004 0.89
33 Triglyceride uptake and lipoprotein lipase-generated fatty acid spillover in the splanchnic bed of dogs. Diabetes 2007 0.89
34 Glucagon's actions are modified by the combination of epinephrine and gluconeogenic precursor infusion. Am J Physiol Endocrinol Metab 2003 0.88
35 Effects of hyperglycemia, glucagon, and epinephrine on renal glucose release in the conscious dog. Metabolism 2004 0.88
36 Involvement of the vagus nerves in the regulation of basal hepatic glucose production in conscious dogs. Am J Physiol Endocrinol Metab 2002 0.88
37 Effects of fructose on hepatic glucose metabolism. Curr Opin Clin Nutr Metab Care 2003 0.88
38 Impact of continuous and pulsatile insulin delivery on net hepatic glucose uptake. Am J Physiol Endocrinol Metab 2005 0.88
39 Inhibition of dipeptidyl peptidase-4 by vildagliptin during glucagon-like Peptide 1 infusion increases liver glucose uptake in the conscious dog. Diabetes 2008 0.87
40 Insulin sensitively controls the glucagon response to mild hypoglycemia in the dog. Diabetes 2002 0.86
41 Portal vein glucose entry triggers a coordinated cellular response that potentiates hepatic glucose uptake and storage in normal but not high-fat/high-fructose-fed dogs. Diabetes 2012 0.86
42 Impact of a glycogen phosphorylase inhibitor and metformin on basal and glucagon-stimulated hepatic glucose flux in conscious dogs. J Pharmacol Exp Ther 2011 0.86
43 Effects of insulin deficiency or excess on hepatic gluconeogenic flux during glycogenolytic inhibition in the conscious dog. Diabetes 2002 0.85
44 Inhalation of human insulin is associated with improved insulin action compared with subcutaneous injection and endogenous secretion in dogs. J Pharmacol Exp Ther 2006 0.85
45 Hepatic glycogen supercompensation activates AMP-activated protein kinase, impairs insulin signaling, and reduces glycogen deposition in the liver. Diabetes 2011 0.84
46 Intraportally delivered GLP-1, in the presence of hyperglycemia induced via peripheral glucose infusion, does not change whole body glucose utilization. Am J Physiol Endocrinol Metab 2007 0.84
47 Unlike mice, dogs exhibit effective glucoregulation during low-dose portal and peripheral glucose infusion. Am J Physiol Endocrinol Metab 2003 0.84
48 Effects of fasting and glucocorticoids on hepatic gluconeogenesis assessed using two independent methods in vivo. Am J Physiol Endocrinol Metab 2002 0.83
49 Portal glucose infusion exerts an incretin effect associated with changes in pancreatic neural activity in conscious dogs. Metabolism 2002 0.83
50 Effects of hyperglycemia on hepatic gluconeogenic flux during glycogen phosphorylase inhibition in the conscious dog. Am J Physiol Endocrinol Metab 2003 0.83
51 Effect of the glucagon-like peptide-1 receptor agonist lixisenatide on postprandial hepatic glucose metabolism in the conscious dog. Am J Physiol Endocrinol Metab 2013 0.82
52 Interaction of glucagon and epinephrine in the control of hepatic glucose production in the conscious dog. Am J Physiol Endocrinol Metab 2002 0.82
53 A soluble guanylate cyclase-dependent mechanism is involved in the regulation of net hepatic glucose uptake by nitric oxide in vivo. Diabetes 2010 0.82
54 The effect of an acute elevation of NEFA concentrations on glucagon-stimulated hepatic glucose output. Am J Physiol Endocrinol Metab 2006 0.81
55 Portal 5-hydroxytryptophan infusion enhances glucose disposal in conscious dogs. Am J Physiol Endocrinol Metab 2005 0.81
56 Portal infusion of amino acids is more efficient than peripheral infusion in stimulating liver protein synthesis at the same hepatic amino acid load in dogs. Am J Clin Nutr 2008 0.81
57 Effect of 11 beta-hydroxysteroid dehydrogenase-1 inhibition on hepatic glucose metabolism in the conscious dog. Am J Physiol Endocrinol Metab 2010 0.81
58 Interaction of a selective serotonin reuptake inhibitor with insulin in the control of hepatic glucose uptake in conscious dogs. Am J Physiol Endocrinol Metab 2004 0.81
59 Islet auto-transplantation into an omental or splenic site results in a normal beta cell but abnormal alpha cell response to mild non-insulin-induced hypoglycemia. Am J Transplant 2005 0.81
60 Liver glycogen loading dampens glycogen synthesis seen in response to either hyperinsulinemia or intraportal glucose infusion. Diabetes 2012 0.80
61 Canine body composition quantification using 3 tesla fat-water MRI. J Magn Reson Imaging 2013 0.80
62 Selective antagonism of the hepatic glucocorticoid receptor reduces hepatic glucose production. Metabolism 2006 0.80
63 Inhalation of human insulin (exubera) augments the efficiency of muscle glucose uptake in vivo. Diabetes 2006 0.80
64 The effect of vagal cooling on canine hepatic glucose metabolism in the presence of hyperglycemia of peripheral origin. Metabolism 2007 0.80
65 Portal infusion of escitalopram enhances hepatic glucose disposal in conscious dogs. Eur J Pharmacol 2009 0.79
66 Simulated first-phase insulin release using Humulin or insulin analog HIM2 is associated with prolonged improvement in postprandial glycemia. Am J Physiol Endocrinol Metab 2005 0.79
67 Glucagon's yin and yang effects on hepatic glucose production. Nat Med 2013 0.78
68 Inclusion of low amounts of fructose with an intraportal glucose load increases net hepatic glucose uptake in the presence of relative insulin deficiency in dog. Am J Physiol Endocrinol Metab 2005 0.77
69 Hepatic portal venous delivery of a nitric oxide synthase inhibitor enhances net hepatic glucose uptake. Am J Physiol Endocrinol Metab 2008 0.76
70 Interaction of free fatty acids and epinephrine in regulating hepatic glucose production in conscious dogs. Am J Physiol Endocrinol Metab 2003 0.76
71 Intraportal administration of neuropeptide Y and hepatic glucose metabolism. Am J Physiol Regul Integr Comp Physiol 2008 0.76
72 Effects of intraportal exenatide on hepatic glucose metabolism in the conscious dog. Am J Physiol Endocrinol Metab 2013 0.76
73 Vagal cooling and concomitant portal norepinephrine infusion do not reduce net hepatic glucose uptake in conscious dogs. Am J Physiol Regul Integr Comp Physiol 2004 0.76
74 Hepatic glycogen can regulate hypoglycemic counterregulation via a liver-brain axis. J Clin Invest 2016 0.76
75 Endogenously released GLP-1 is not sufficient to alter postprandial glucose regulation in the dog. Endocrine 2011 0.76
76 Inhaled insulin is associated with prolonged enhancement of glucose disposal in muscle and liver in the canine. J Pharmacol Exp Ther 2008 0.75
77 Dissecting the actions of widely used diabetes drugs. Nat Med 2013 0.75
78 A cyclic guanosine monophosphate-dependent pathway can regulate net hepatic glucose uptake in vivo. Diabetes 2012 0.75
79 Portal glucose delivery stimulates muscle but not liver protein metabolism. Am J Physiol Endocrinol Metab 2012 0.75
80 Chronic hepatic artery ligation does not prevent liver from differentiating portal vs. peripheral glucose delivery. Am J Physiol Endocrinol Metab 2003 0.75
81 A fall in portal vein insulin does not cause the alpha-cell response to mild, non-insulin-induced hypoglycemia in conscious dogs. Metabolism 2003 0.75
82 Effects of cyclosporine A and prednisone treatment on mixed meal disposition in dogs with hepatic denervation. JPEN J Parenter Enteral Nutr 2002 0.75