Published in J Neurosci on December 03, 2003
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Atorvastatin attenuates the production of IL-1β, IL-6, and TNF-α in the hippocampus of an amyloid β1-42-induced rat model of Alzheimer's disease. Clin Interv Aging (2013) 1.69
The neurovascular unit and combination treatment strategies for stroke. Trends Pharmacol Sci (2012) 1.66
Statins and delirium during critical illness: a multicenter, prospective cohort study. Crit Care Med (2014) 1.60
Combined medication of lovastatin with rolipram suppresses severity of experimental autoimmune encephalomyelitis. Exp Neurol (2008) 1.54
Continued statin therapy could improve the outcome after spontaneous intracerebral hemorrhage. Neurosurg Rev (2012) 1.46
Neurorestorative treatment of stroke: cell and pharmacological approaches. NeuroRx (2006) 1.37
Neuroglobin attenuates beta-amyloid neurotoxicity in vitro and transgenic Alzheimer phenotype in vivo. Proc Natl Acad Sci U S A (2007) 1.32
Simvastatin and atorvastatin improve neurological outcome after experimental intracerebral hemorrhage. Stroke (2009) 1.18
Multifunctional drugs for head injury. Neurotherapeutics (2009) 1.16
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors in the treatment of central nervous system diseases. Arch Neurol (2010) 1.08
Statins and neuroprotection: a prescription to move the field forward. Ann N Y Acad Sci (2010) 1.05
Increase in phosphorylation of Akt and its downstream signaling targets and suppression of apoptosis by simvastatin after traumatic brain injury. J Neurosurg (2008) 1.04
Immunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitis. Am J Pathol (2006) 1.03
The relationship between statin use and open-angle glaucoma. Ophthalmology (2012) 0.98
Nitric oxide: considerations for the treatment of ischemic stroke. J Cereb Blood Flow Metab (2012) 0.97
Statin's excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling. J Neurosci (2009) 0.96
Blood-brain barrier dysfunction-induced inflammatory signaling in brain pathology and epileptogenesis. Epilepsia (2012) 0.95
Statin inhibits kainic acid-induced seizure and associated inflammation and hippocampal cell death. Neurosci Lett (2008) 0.93
Cholesterol modulates open probability and desensitization of NMDA receptors. J Physiol (2015) 0.91
Rosuvastatin induces delayed preconditioning against oxygen-glucose deprivation in cultured cortical neurons. Am J Physiol Cell Physiol (2008) 0.90
Simvastatin enhances hippocampal long-term potentiation in C57BL/6 mice. Neuroscience (2009) 0.90
Treatment targets in intracerebral hemorrhage. Neurotherapeutics (2011) 0.89
Statins in traumatic brain injury. Neurotherapeutics (2010) 0.89
Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation. Neuroscience (2011) 0.88
Long-lasting benefits after treatment of traumatic brain injury (TBI) in rats with combination therapy of marrow stromal cells (MSCs) and simvastatin. J Neurotrauma (2008) 0.87
Statins Protect the Blood Brain Barrier Acutely after Experimental Intracerebral Hemorrhage. J Behav Brain Sci (2012) 0.87
Endothelial cells and astrocytes: a concerto en duo in ischemic pathophysiology. Int J Cell Biol (2012) 0.86
Isoprenoids and related pharmacological interventions: potential application in Alzheimer's disease. Mol Neurobiol (2012) 0.85
Administration of simvastatin after kainic acid-induced status epilepticus restrains chronic temporal lobe epilepsy. PLoS One (2011) 0.85
Vascular recovery promoted by atorvastatin and simvastatin after experimental intracerebral hemorrhage: magnetic resonance imaging and histological study. J Neurosurg (2010) 0.85
Pilot trial of simvastatin in the treatment of sporadic inclusion-body myositis. Neurol Sci (2011) 0.85
Molecular mechanisms underlying the effects of statins in the central nervous system. Int J Mol Sci (2014) 0.83
Statins Enhance Expression of Growth Factors and Activate the PI3K/Akt-mediated Signaling Pathway after Experimental Intracerebral Hemorrhage. World J Neurosci (2012) 0.81
The neuroprotective effect of two statins: simvastatin and pravastatin on a streptozotocin-induced model of Alzheimer's disease in rats. J Neural Transm (Vienna) (2011) 0.81
Cholesterol-independent effects of methyl-β-cyclodextrin on chemical synapses. PLoS One (2012) 0.80
Lovastatin modulates glycogen synthase kinase-3β pathway and inhibits mossy fiber sprouting after pilocarpine-induced status epilepticus. PLoS One (2012) 0.80
Effect of Coenzyme Q10 and green tea on plasma and liver lipids, platelet aggregation, TBARS production and erythrocyte Na leak in simvastatin treated hypercholesterolmic rats. Nutr Res Pract (2007) 0.80
Simvastatin induces cell death in a mouse cerebellar slice culture (CSC) model of developmental myelination. Exp Neurol (2008) 0.80
Simvastatin attenuates axonal injury after experimental traumatic brain injury and promotes neurite outgrowth of primary cortical neurons. Brain Res (2012) 0.78
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Rosuvastatin induces delayed preconditioning against L-glutamate excitotoxicity in cultured cortical neurons. Neurochem Int (2009) 0.77
Neuroprotective effect of systemic and/or intravitreal rosuvastatin administration in rat glaucoma model. Int J Ophthalmol (2016) 0.75
Analysis of hippocampal gene expression profile of Alzheimer's disease model rats using genome chip bioinformatics. Neural Regen Res (2012) 0.75
Simvastatin protects ischemic spinal cord injury from cell death and cytotoxicity through decreasing oxidative stress: in vitro primary cultured rat spinal cord model under oxygen and glucose deprivation-reoxygenation conditions. J Orthop Surg Res (2017) 0.75
Simvastatin treatment enhances NMDAR-mediated synaptic transmission by upregulating the surface distribution of the GluN2B subunit. Cell Mol Neurobiol (2014) 0.75
The ocular toxicity and pharmacokinetics of simvastatin following intravitreal injection in mice. Int J Ophthalmol (2017) 0.75
The beneficial effects of HMG-CoA reductase inhibitors in the processes of neurodegeneration. Metab Brain Dis (2017) 0.75
A putative human breast stem cell population is enriched for steroid receptor-positive cells. Dev Biol (2005) 3.19
Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways. J Natl Cancer Inst (2007) 2.75
A detailed mammosphere assay protocol for the quantification of breast stem cell activity. J Mammary Gland Biol Neoplasia (2012) 1.98
Safety and efficacy of esreboxetine in patients with fibromyalgia: a fourteen-week, randomized, double-blind, placebo-controlled, multicenter clinical trial. Arthritis Rheum (2012) 1.48
Wnt pathway activity in breast cancer sub-types and stem-like cells. PLoS One (2013) 1.21
A novel method for modeling facial allodynia associated with migraine in awake and freely moving rats. J Neurosci Methods (2009) 0.94
Prior exposure to repeated morphine potentiates mechanical allodynia induced by peripheral inflammation and neuropathy. Brain Behav Immun (2012) 0.87
Differential coupling of M1 muscarinic and alpha7 nicotinic receptors to inhibition of pemphigus acantholysis. J Biol Chem (2007) 0.84
A comparison of sumanirole versus placebo or ropinirole for the treatment of patients with early Parkinson's disease. Mov Disord (2007) 0.82
Efficacy and tolerability of sumanirole in restless legs syndrome: a phase II, randomized, double-blind, placebo-controlled, dose-response study. Sleep Med (2007) 0.79
Sumanirole versus placebo or ropinirole for the adjunctive treatment of patients with advanced Parkinson's disease. Mov Disord (2007) 0.79
Unilateral T13 and L1 dorsal root avulsion: methods for a novel model of central neuropathic pain. Methods Mol Biol (2012) 0.78
Methotrexate dose delivery is more important than ciclosporin level in graft-versus-host disease prophylaxis following T-replete reduced-intensity sibling allogeneic stem cell transplant. Int J Hematol (2011) 0.78
Lack of caveolin-1 (P132L) somatic mutations in breast cancer. Breast Cancer Res Treat (2012) 0.78
Multifunctionalized iron oxide nanoparticles for selective drug delivery to CD44-positive cancer cells. Nanotechnology (2016) 0.78
Indwelling supradural catheters for induction of facial allodynia: surgical procedures, application of inflammatory stimuli, and behavioral testing. Methods Mol Biol (2012) 0.76
Laying Waste to Mercury: Inexpensive Sorbents Made from Sulfur and Recycled Cooking Oils. Chemistry (2017) 0.75