Phyllis B Silver

Author PubWeight™ 32.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category. J Exp Med 2008 5.25
2 Autoimmune uveitis elicited with antigen-pulsed dendritic cells has a distinct clinical signature and is driven by unique effector mechanisms: initial encounter with autoantigen defines disease phenotype. J Immunol 2007 1.65
3 Calcitriol suppresses antiretinal autoimmunity through inhibitory effects on the Th17 effector response. J Immunol 2009 1.57
4 Essential role of the MyD88 pathway, but nonessential roles of TLRs 2, 4, and 9, in the adjuvant effect promoting Th1-mediated autoimmunity. J Immunol 2005 1.50
5 An immunologically privileged retinal antigen elicits tolerance: major role for central selection mechanisms. J Exp Med 2003 1.44
6 Endogenous IRBP can be dispensable for generation of natural CD4+CD25+ regulatory T cells that protect from IRBP-induced retinal autoimmunity. J Exp Med 2006 1.34
7 A humanized model of experimental autoimmune uveitis in HLA class II transgenic mice. J Clin Invest 2003 1.32
8 Activation of invariant NKT cells ameliorates experimental ocular autoimmunity by a mechanism involving innate IFN-gamma production and dampening of the adaptive Th1 and Th17 responses. J Immunol 2008 1.26
9 The living eye "disarms" uncommitted autoreactive T cells by converting them to Foxp3(+) regulatory cells following local antigen recognition. J Immunol 2012 1.18
10 Repertoire analysis and new pathogenic epitopes of IRBP in C57BL/6 (H-2b) and B10.RIII (H-2r) mice. Invest Ophthalmol Vis Sci 2008 1.09
11 Breakdown of immune privilege and spontaneous autoimmunity in mice expressing a transgenic T cell receptor specific for a retinal autoantigen. J Autoimmun 2013 1.07
12 Rodent models of experimental autoimmune uveitis. Methods Mol Biol 2012 1.06
13 Altered chemokine profile associated with exacerbated autoimmune pathology under conditions of genetic interferon-gamma deficiency. Invest Ophthalmol Vis Sci 2007 1.06
14 The role of TLR2, TRL3, TRL4, and TRL9 signaling in the pathogenesis of autoimmune disease in a retinal autoimmunity model. Invest Ophthalmol Vis Sci 2010 1.00
15 Mouse models of experimental autoimmune uveitis. Ophthalmic Res 2008 0.97
16 Disruption of CD40/CD40-ligand interactions in a retinal autoimmunity model results in protection without tolerance. J Immunol 2005 0.96
17 Inhibition of experimental auto-immune uveitis by the A3 adenosine receptor agonist CF101. Int J Mol Med 2011 0.92
18 Common genetic determinants of uveitis shared with other autoimmune disorders. J Immunol 2008 0.92
19 Uveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of uveitis and identify autoaggressive T cells. J Immunol 2011 0.88
20 Cholera toxin prevents Th1-mediated autoimmune disease by inducing immune deviation. J Immunol 2004 0.86
21 Antigen/MHC class II/Ig dimers for study of uveitogenic T cells: IRBP p161-180 presented by both IA and IE molecules. Invest Ophthalmol Vis Sci 2005 0.86
22 Abrogation of anti-retinal autoimmunity in IL-10 transgenic mice due to reduced T cell priming and inhibition of disease effector mechanisms. J Immunol 2008 0.84
23 Inhibitory peptide analogs derived from a major uveitogenic epitope protect from antiretinal autoimmunity by inducing type 2 and regulatory T cells. J Leukoc Biol 2008 0.83
24 Dissociating the enhancing and inhibitory effects of pertussis toxin on autoimmune disease. J Immunol 2003 0.83
25 Tgf-beta inhibits activation and uveitogenicity of primary but not of fully polarized retinal antigen-specific memory-effector T cells. Invest Ophthalmol Vis Sci 2003 0.79
26 Methimazole protects from experimental autoimmune uveitis (EAU) by inhibiting antigen presenting cell function and reducing antigen priming. J Leukoc Biol 2003 0.77
27 Correction: Retina-Specific T Regulatory Cells Bring About Resolution and Maintain Remission of Autoimmune Uveitis. J Immunol 2015 0.77