Published in J Exp Med on December 01, 2003
Dectin-1 is required for beta-glucan recognition and control of fungal infection. Nat Immunol (2006) 6.36
The isolation and characterization of murine macrophages. Curr Protoc Immunol (2008) 4.86
Acute lower respiratory tract infection. N Engl J Med (2008) 3.70
Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production. Blood (2005) 3.57
The beta-glucan receptor dectin-1 recognizes specific morphologies of Aspergillus fumigatus. PLoS Pathog (2005) 3.13
Aspergillus fumigatus triggers inflammatory responses by stage-specific beta-glucan display. PLoS Pathog (2005) 3.01
Alveolar macrophages: plasticity in a tissue-specific context. Nat Rev Immunol (2014) 2.71
A drug-sensitive genetic network masks fungi from the immune system. PLoS Pathog (2006) 2.65
The C-type lectin receptors CLEC-2 and Dectin-1, but not DC-SIGN, signal via a novel YXXL-dependent signaling cascade. J Biol Chem (2007) 2.24
Caspofungin modulates inflammatory responses to Aspergillus fumigatus through stage-specific effects on fungal beta-glucan exposure. J Infect Dis (2008) 1.82
Aspergillus fumigatus: principles of pathogenesis and host defense. Eukaryot Cell (2007) 1.74
Colonization by Pneumocystis jirovecii and its role in disease. Clin Microbiol Rev (2012) 1.68
Mnt1p and Mnt2p of Candida albicans are partially redundant alpha-1,2-mannosyltransferases that participate in O-linked mannosylation and are required for adhesion and virulence. J Biol Chem (2004) 1.66
Innate immunity to the pathogenic fungus Coccidioides posadasii is dependent on Toll-like receptor 2 and Dectin-1. Infect Immun (2005) 1.53
Elucidating the pathogenesis of spores from the human fungal pathogen Cryptococcus neoformans. Infect Immun (2009) 1.45
Pneumocystis cell wall beta-glucans stimulate alveolar epithelial cell chemokine generation through nuclear factor-kappaB-dependent mechanisms. Am J Respir Cell Mol Biol (2005) 1.45
C-type lectins and phagocytosis. Immunobiology (2009) 1.41
Phospholipase Cgamma2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells. J Biol Chem (2009) 1.38
Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis. PLoS Pathog (2008) 1.34
Toll-like receptor 2 mediates alveolar macrophage response to Pneumocystis murina. Infect Immun (2006) 1.34
CD4+ T cell-independent DNA vaccination against opportunistic infections. J Clin Invest (2005) 1.33
Conserved natural IgM antibodies mediate innate and adaptive immunity against the opportunistic fungus Pneumocystis murina. J Exp Med (2010) 1.29
Transcriptome analysis of Pseudomonas aeruginosa after interaction with human airway epithelial cells. Infect Immun (2004) 1.29
Echinocandin treatment of pneumocystis pneumonia in rodent models depletes cysts leaving trophic burdens that cannot transmit the infection. PLoS One (2010) 1.26
Pneumocystis carinii activates the NF-kappaB signaling pathway in alveolar epithelial cells. Infect Immun (2005) 1.24
Rapid host defense against Aspergillus fumigatus involves alveolar macrophages with a predominance of alternatively activated phenotype. PLoS One (2011) 1.21
Pneumocystis activates human alveolar macrophage NF-kappaB signaling through mannose receptors. Infect Immun (2004) 1.16
Importance of TLR2 in early innate immune response to acute pulmonary infection with Porphyromonas gingivalis in mice. J Immunol (2008) 1.16
Role of macrophages in early host resistance to respiratory Acinetobacter baumannii infection. PLoS One (2012) 1.12
IL-33 and M2a alveolar macrophages promote lung defense against the atypical fungal pathogen Pneumocystis murina. J Immunol (2011) 1.10
Self and nonself recognition through C-type lectin receptor, Mincle. Self Nonself (2010) 1.08
The Japanese experience with biologic therapies for rheumatoid arthritis. Nat Rev Rheumatol (2010) 1.07
Scavenger receptor A dampens induction of inflammation in response to the fungal pathogen Pneumocystis carinii. Infect Immun (2007) 1.03
Dectin-1 Fc targeting of aspergillus fumigatus beta-glucans augments innate defense against invasive pulmonary aspergillosis. Antimicrob Agents Chemother (2007) 1.02
Dectin-1: a role in antifungal defense and consequences of genetic polymorphisms in humans. Mamm Genome (2010) 1.01
Cdc42 and RhoB activation are required for mannose receptor-mediated phagocytosis by human alveolar macrophages. Mol Biol Cell (2004) 1.00
CXCR3 and IFN protein-10 in Pneumocystis pneumonia. J Immunol (2006) 0.98
Decreased inflammatory response in Toll-like receptor 2 knockout mice is associated with exacerbated Pneumocystis pneumonia. Microbes Infect (2007) 0.94
Current understanding of Pneumocystis immunology. Future Microbiol (2010) 0.94
Cytokines and the regulation of fungus-specific CD4 T cell differentiation. Cytokine (2011) 0.90
Classical versus alternative macrophage activation: the Ying and the Yang in host defense against pulmonary fungal infections. Mucosal Immunol (2014) 0.90
Exogenous heat-killed Escherichia coli improves alveolar macrophage activity and reduces Pneumocystis carinii lung burden in infant mice. Infect Immun (2007) 0.89
Downregulation of PU.1 leads to decreased expression of Dectin-1 in alveolar macrophages during Pneumocystis pneumonia. Infect Immun (2010) 0.89
Dectin immunoadhesins and pneumocystis pneumonia. Infect Immun (2013) 0.88
Pathological and protective immunity to Pneumocystis infection. Semin Immunopathol (2014) 0.88
The absence of Hck, Fgr, and Lyn tyrosine kinases augments lung innate immune responses to Pneumocystis murina. Infect Immun (2009) 0.88
Immune modulation with sulfasalazine attenuates immunopathogenesis but enhances macrophage-mediated fungal clearance during Pneumocystis pneumonia. PLoS Pathog (2010) 0.87
Alveolar macrophages in neonatal mice are inherently unresponsive to Pneumocystis murina infection. Infect Immun (2012) 0.87
Striking a balance: fungal commensalism versus pathogenesis. Curr Opin Microbiol (2013) 0.86
Pneumocystis mediates overexpression of antizyme inhibitor resulting in increased polyamine levels and apoptosis in alveolar macrophages. J Biol Chem (2009) 0.86
B Lymphocytes Are Required during the Early Priming of CD4+ T Cells for Clearance of Pneumocystis Infection in Mice. J Immunol (2015) 0.86
Stage-specific innate immune recognition of Aspergillus fumigatus and modulation by echinocandin drugs. Med Mycol (2008) 0.85
Fungal surface and innate immune recognition of filamentous fungi. Front Microbiol (2011) 0.84
Role and relevance of mast cells in fungal infections. Front Immunol (2012) 0.84
In vitro effector activity of Pneumocystis murina-specific T-cytotoxic-1 CD8+ T cells: role of granulocyte-macrophage colony-stimulating factor. Infect Immun (2005) 0.83
Anti-CD20 antibody therapy and susceptibility to Pneumocystis pneumonia. Infect Immun (2015) 0.83
Mononuclear phagocyte-mediated antifungal immunity: the role of chemotactic receptors and ligands. Cell Mol Life Sci (2015) 0.83
Concurrent exposure to a dectin-1 agonist suppresses the Th2 response to epicutaneously introduced antigen in mice. J Biomed Sci (2013) 0.82
Dectin-1 Activation by a Natural Product β-Glucan Converts Immunosuppressive Macrophages into an M1-like Phenotype. J Immunol (2015) 0.82
Characterization of a distinct host response profile to Pneumocystis murina asci during clearance of pneumocystis pneumonia. Infect Immun (2013) 0.82
Novel pneumocystis antigen discovery using fungal surface proteomics. Infect Immun (2014) 0.81
Modulation of inflammasome-mediated pulmonary immune activation by type I IFNs protects bone marrow homeostasis during systemic responses to Pneumocystis lung infection. J Immunol (2013) 0.81
Innate receptors and cellular defense against pulmonary infections. J Immunol (2014) 0.80
Neutropenia exacerbates infection by Acinetobacter baumannii clinical isolates in a murine wound model. Front Microbiol (2015) 0.80
Production of functional soluble Dectin-1 glycoprotein using an IRES-linked destabilized-dihydrofolate reductase expression vector. PLoS One (2012) 0.80
Experimental Pneumocystis lung infection promotes M2a alveolar macrophage-derived MMP12 production. Am J Physiol Lung Cell Mol Physiol (2012) 0.79
Pneumocystis murina colonization in immunocompetent surfactant protein A deficient mice following environmental exposure. Respir Res (2009) 0.79
Eosinophils Contribute to Early Clearance of Pneumocystis murina Infection. J Immunol (2015) 0.79
Chitinases in Pneumocystis carinii pneumonia. Med Microbiol Immunol (2012) 0.78
B cells modulate systemic responses to Pneumocystis murina lung infection and protect on-demand hematopoiesis via T cell-independent innate mechanisms when type I interferon signaling is absent. Infect Immun (2014) 0.78
Immune Modulation as Adjunctive Therapy for Pneumocystis pneumonia. Interdiscip Perspect Infect Dis (2011) 0.77
Host genetics of invasive Aspergillus and Candida infections. Semin Immunopathol (2014) 0.77
Differential Macrophage Polarization from Pneumocystis in Immunocompetent and Immunosuppressed Hosts: Potential Adjunctive Therapy during Pneumonia. Infect Immun (2017) 0.76
Role of interleukin-23-dependent antifungal immune responses in dendritic cell-vaccinated mice. Infect Immun (2011) 0.76
The Interaction of Pneumocystis with the C-Type Lectin Receptor Mincle Exerts a Significant Role in Host Defense against Infection. J Immunol (2017) 0.75
An Emerging Role of B Cell Immunity in Susceptibility to Pneumocystis Pneumonia. Am J Respir Cell Mol Biol (2017) 0.75
Polymorphisms of the immune-modulating receptor dectin-1 in pigs: their functional influence and distribution in pig populations. Immunogenetics (2016) 0.75
Killing activity of neutrophils is mediated through activation of proteases by K+ flux. Nature (2002) 7.53
Immune recognition. A new receptor for beta-glucans. Nature (2001) 6.54
Dectin-1 mediates the biological effects of beta-glucans. J Exp Med (2003) 5.82
Dectin-1 is a major beta-glucan receptor on macrophages. J Exp Med (2002) 4.87
Pattern recognition receptors: doubling up for the innate immune response. Cell (2002) 4.84
Caspofungin. Clin Infect Dis (2003) 3.03
A new model of Pneumocystis carinii infection in mice selectively depleted of helper T lymphocytes. J Clin Invest (1990) 3.03
The interaction in vitro of Pneumocystis carinii with macrophages and L-cells. J Exp Med (1978) 2.93
Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning. J Biol Chem (2000) 2.83
Mannose receptor-mediated regulation of serum glycoprotein homeostasis. Science (2002) 2.75
Uptake of Pneumocystis carinii mediated by the macrophage mannose receptor. Nature (1991) 2.73
Improved survival with highly active antiretroviral therapy in HIV-infected patients with severe Pneumocystis carinii pneumonia. AIDS (2003) 2.18
Stable Mn(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo. J Biol Chem (1994) 2.15
CD4+ T cell-independent vaccination against Pneumocystis carinii in mice. J Clin Invest (2001) 1.76
The role of alveolar macrophages in Pneumocystis carinii degradation and clearance from the lung. J Clin Invest (1997) 1.76
Host species-specific antigenic variation of a mannosylated surface glycoprotein of Pneumocystis carinii. J Infect Dis (1992) 1.69
Reduced binding and phagocytosis of Pneumocystis carinii by alveolar macrophages from persons infected with HIV-1 correlates with mannose receptor downregulation. J Clin Invest (1998) 1.61
Mechanisms of host defense against Candida species. I. Phagocytosis by monocytes and monocyte-derived macrophages. J Immunol (1991) 1.58
Yeast glucan in the cyst wall of Pneumocystis carinii. J Protozool (1989) 1.54
IFN-gamma and CD8+ T cells restore host defenses against Pneumocystis carinii in mice depleted of CD4+ T cells. J Immunol (1999) 1.54
The changing pattern of AIDS-defining illnesses with the introduction of highly active antiretroviral therapy (HAART)in a London clinic. J Infect (2001) 1.43
Isolated Pneumocystis carinii cell wall glucan provokes lower respiratory tract inflammatory responses. J Immunol (2000) 1.39
Pneumocystis carinii stimulates tumor necrosis factor-alpha release from alveolar macrophages through a beta-glucan-mediated mechanism. J Immunol (1993) 1.38
Pneumocystis carinii infection in transgenic B cell-deficient mice. J Infect Dis (1996) 1.35
Effect of antiretroviral therapy on the incidence of bacterial pneumonia in patients with advanced HIV infection. Am J Respir Crit Care Med (2000) 1.35
Increased host resistance against Pneumocystis carinii pneumonia in gammadelta T-cell-deficient mice: protective role of gamma interferon and CD8(+) T cells. Infect Immun (2002) 1.30
Absence of the macrophage mannose receptor in mice does not increase susceptibility to Pneumocystis carinii infection in vivo. Infect Immun (2003) 1.22
Normal host defense during systemic candidiasis in mannose receptor-deficient mice. Infect Immun (2003) 1.18
Pneumocystis carinii glycoprotein A binds macrophage mannose receptors. Infect Immun (1995) 1.18
Pneumocystis carinii host origin defines the antibody specificity and protective response induced by immunization. J Infect Dis (1997) 1.11
Pneumocystis carinii induces an oxidative burst in alveolar macrophages. Infect Immun (1992) 1.09
Pneumocystis carinii. Br Med Bull (2002) 1.09
Pneumocystis carinii: oxygen uptake, antioxidant enzymes, and susceptibility to oxygen-mediated damage. Infect Immun (1984) 1.06
Alveolar macrophages from human immunodeficiency virus-infected persons demonstrate impaired oxidative burst response to Pneumocystis carinii in vitro. Am J Respir Cell Mol Biol (2000) 1.06
Beta-glucan from Pneumocystis carinii stimulates TNF alpha release from alveolar macrophages. J Eukaryot Microbiol (1999) 0.95
Gamma interferon stimulates rat alveolar macrophages to kill Pneumocystis carinii by L-arginine- and tumor necrosis factor-dependent mechanisms. Infect Immun (1999) 0.93
Lymphocytes in host defense against Pneumocystis carinii. Semin Respir Infect (1998) 0.93
Analysis of Pneumocystis carinii cyst wall. II. Sugar composition. J Protozool (1990) 0.93
Pneumocystis carinii enhances soluble mannose receptor production by macrophages. Microbes Infect (2000) 0.90
Pyogenic bacterial lower respiratory tract infection in human immunodeficiency virus-infected patients. Eur Respir J Suppl (2002) 0.89
Alveolar macrophage interactions with Pneumocystis carinii. J Lab Clin Med (1999) 0.89
Pneumocystis carinii-induced activation of the respiratory burst in human monocytes and macrophages. Clin Exp Immunol (1994) 0.88
A soluble mannose receptor immunoadhesin enhances phagocytosis of Pneumocystis carinii by human polymorphonuclear leukocytes in vitro. Scand J Immunol (2000) 0.88
Parallel phylogenies of Pneumocystis species and their mammalian hosts. J Eukaryot Microbiol (2001) 0.86
Phospholipase D and priming of the respiratory burst by H(2)O(2) in NR8383 alveolar macrophages. Am J Respir Cell Mol Biol (2000) 0.85
Alternative activation of macrophages: an immunologic functional perspective. Annu Rev Immunol (2009) 11.63
The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity (2008) 10.55
Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J Immunol (2006) 9.82
IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat Med (2008) 9.05
Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat Immunol (2007) 8.92
Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor binding. Science (2010) 7.41
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. Nat Immunol (2007) 6.67
Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae. J Exp Med (2005) 6.37
Dectin-1 is required for beta-glucan recognition and control of fungal infection. Nat Immunol (2006) 6.36
Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins. Immunity (2005) 6.21
Differential oestrogen receptor binding is associated with clinical outcome in breast cancer. Nature (2012) 5.84
Dectin-1 mediates the biological effects of beta-glucans. J Exp Med (2003) 5.82
Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis. Science (2012) 5.34
Human dectin-1 deficiency and mucocutaneous fungal infections. N Engl J Med (2009) 5.27
A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nat Immunol (2009) 5.26
An integrated model of the recognition of Candida albicans by the innate immune system. Nat Rev Microbiol (2008) 5.13
Dectin-1 is a major beta-glucan receptor on macrophages. J Exp Med (2002) 4.87
Targeting IL-17 and TH17 cells in chronic inflammation. Nat Rev Drug Discov (2012) 4.70
ChIP-seq: using high-throughput sequencing to discover protein-DNA interactions. Methods (2009) 4.69
Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut. Nat Med (2008) 4.68
Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection. J Immunol (2003) 4.45
Unravelling mononuclear phagocyte heterogeneity. Nat Rev Immunol (2010) 4.25
Interleukin-17A mediates acquired immunity to pneumococcal colonization. PLoS Pathog (2008) 4.05
Control of TH17 cells occurs in the small intestine. Nature (2011) 4.03
A CTCF-independent role for cohesin in tissue-specific transcription. Genome Res (2010) 3.89
An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans. Cell Host Microbe (2009) 3.52
Waves of retrotransposon expansion remodel genome organization and CTCF binding in multiple mammalian lineages. Cell (2012) 3.48
TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice. J Immunol (2008) 3.42
IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. J Clin Invest (2010) 3.40
Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Francisella tularensis. Immunity (2009) 3.33
Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells. Immunity (2013) 3.26
Th17 cells and mucosal host defense. Semin Immunol (2007) 3.17
Retracted Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth. J Exp Med (2011) 3.15
The beta-glucan receptor dectin-1 recognizes specific morphologies of Aspergillus fumigatus. PLoS Pathog (2005) 3.13
The development of inducible bronchus-associated lymphoid tissue depends on IL-17. Nat Immunol (2011) 3.13
Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection. J Exp Med (2009) 3.12
Critical role of IL-17 receptor signaling in acute TNBS-induced colitis. Inflamm Bowel Dis (2006) 3.09
The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages. J Immunol (2002) 3.09
IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J Immunol (2005) 3.02
Proinflammatory T helper type 17 cells are effective B-cell helpers. Proc Natl Acad Sci U S A (2010) 2.88
Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages. Blood (2004) 2.84
A role for fungal {beta}-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice. J Exp Med (2005) 2.80
Requisite role for the dectin-1 beta-glucan receptor in pulmonary defense against Aspergillus fumigatus. J Immunol (2009) 2.74
Development and application of a salmonid EST database and cDNA microarray: data mining and interspecific hybridization characteristics. Genome Res (2004) 2.72
Allergic sensitization through the airway primes Th17-dependent neutrophilia and airway hyperresponsiveness. Am J Respir Crit Care Med (2009) 2.72
Blockade of interleukin-17A results in reduced atherosclerosis in apolipoprotein E-deficient mice. Circulation (2010) 2.69
Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype. J Immunol (2006) 2.67
Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection. Infect Immun (2005) 2.66
Macrophage fusion induced by IL-4 alternative activation is a multistage process involving multiple target molecules. Eur J Immunol (2007) 2.63
Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors. Eur J Immunol (2008) 2.62
Scavenger receptors in innate immunity. Curr Opin Immunol (2002) 2.62
Critical role of IL-17RA in immunopathology of influenza infection. J Immunol (2009) 2.51
Early stop polymorphism in human DECTIN-1 is associated with increased candida colonization in hematopoietic stem cell transplant recipients. Clin Infect Dis (2009) 2.49
Tackling human fungal infections. Science (2012) 2.49
The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone. J Cell Biol (2004) 2.41
Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: role of signal transducer and activator of transcription 3. Hepatology (2010) 2.40
Dectin-1 expression and function are enhanced on alternatively activated and GM-CSF-treated macrophages and are negatively regulated by IL-10, dexamethasone, and lipopolysaccharide. J Immunol (2003) 2.38
Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate. J Immunol (2010) 2.38
Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor. Cell Rep (2013) 2.37
TH17 cells in asthma and COPD. Annu Rev Physiol (2010) 2.36
CLEC9A is a novel activation C-type lectin-like receptor expressed on BDCA3+ dendritic cells and a subset of monocytes. J Biol Chem (2008) 2.34
Ligands for the beta-glucan receptor, Dectin-1, assigned using "designer" microarrays of oligosaccharide probes (neoglycolipids) generated from glucan polysaccharides. J Biol Chem (2005) 2.32
Pattern recognition receptors and differentiation antigens define murine myeloid cell heterogeneity ex vivo. Eur J Immunol (2003) 2.30
Immune recognition of Candida albicans beta-glucan by dectin-1. J Infect Dis (2007) 2.24
Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F. J Immunol (2007) 2.24
Innate and adaptive interferons suppress IL-1α and IL-1β production by distinct pulmonary myeloid subsets during Mycobacterium tuberculosis infection. Immunity (2011) 2.19
Cxcr2 and Cxcl5 regulate the IL-17/G-CSF axis and neutrophil homeostasis in mice. J Clin Invest (2012) 2.18
Th17 cells mediate clade-specific, serotype-independent mucosal immunity. Immunity (2011) 2.15
Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences. Blood (2013) 2.14
Fungal beta-glucans and mammalian immunity. Immunity (2003) 2.13
MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis. PLoS Pathog (2009) 2.12
Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: potential therapy for cystic fibrosis. Proc Natl Acad Sci U S A (2004) 2.09
The mannose receptor mediates dengue virus infection of macrophages. PLoS Pathog (2008) 2.09
Interleukin-23 (IL-23)-IL-17 cytokine axis in murine Pneumocystis carinii infection. Infect Immun (2007) 2.08
IL-23 mediates inflammatory responses to mucoid Pseudomonas aeruginosa lung infection in mice. Am J Physiol Lung Cell Mol Physiol (2006) 2.06
Alcohol, host defence and society. Nat Rev Immunol (2002) 2.05
Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation. J Exp Med (2009) 2.03
Stem cells and cell therapies in lung biology and lung diseases. Proc Am Thorac Soc (2008) 1.98
Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes. Nat Immunol (2010) 1.97
Persistence and responsiveness of immunologic memory in the absence of secondary lymphoid organs. Immunity (2006) 1.95