Published in J Appl Physiol (1985) on January 01, 2004
Polycystic ovary syndrome: etiology, pathogenesis and diagnosis. Nat Rev Endocrinol (2011) 3.02
Beyond the Paleolithic prescription: incorporating diversity and flexibility in the study of human diet evolution. Nutr Rev (2013) 2.02
Genome-wide association of anthropometric traits in African- and African-derived populations. Hum Mol Genet (2010) 1.90
Gene-environment interaction and obesity. Nutr Rev (2008) 1.84
Variability in training-induced skeletal muscle adaptation. J Appl Physiol (1985) (2010) 1.75
Redefining metabolic syndrome as a fat storage condition based on studies of comparative physiology. Obesity (Silver Spring) (2013) 1.47
Quantitative trait loci for physical activity traits in mice. Physiol Genomics (2008) 1.45
The great opportunity: Evolutionary applications to medicine and public health. Evol Appl (2008) 1.43
Set points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposity. Dis Model Mech (2011) 1.40
Ten questions about systems biology. J Physiol (2011) 1.36
Genetic architecture of voluntary exercise in an advanced intercross line of mice. Physiol Genomics (2010) 1.30
Cessation of daily wheel running differentially alters fat oxidation capacity in liver, muscle, and adipose tissue. J Appl Physiol (1985) (2008) 1.21
An epistatic genetic basis for physical activity traits in mice. J Hered (2008) 1.19
Glucose clearance is higher in arm than leg muscle in type 2 diabetes. J Physiol (2005) 1.17
The contribution of psychosocial stress to the obesity epidemic: an evolutionary approach. Horm Metab Res (2009) 1.11
Lack of adequate appreciation of physical exercise's complexities can pre-empt appropriate design and interpretation in scientific discovery. J Physiol (2009) 1.10
Current status of the E23K Kir6.2 polymorphism: implications for type-2 diabetes. Hum Genet (2004) 1.10
Genetic variation in the pleiotropic association between physical activity and body weight in mice. Genet Sel Evol (2009) 1.05
Parent-of-origin effects on voluntary exercise levels and body composition in mice. Physiol Genomics (2009) 1.02
Putting desire on a budget: dopamine and energy expenditure, reconciling reward and resources. Front Integr Neurosci (2012) 1.00
Polycystic ovary syndrome: an ancient disorder? Fertil Steril (2010) 0.99
Uncoupling protein-2 modulates the lipid metabolic response to fasting in mice. Am J Physiol Gastrointest Liver Physiol (2008) 0.96
Towards integrated physical activity profiling. PLoS One (2013) 0.95
Elevating optimal human nutrition to a central goal of plant breeding and production of plant-based foods. Plant Sci (2009) 0.95
Adipose tissue and vascular phenotypic modulation by voluntary physical activity and dietary restriction in obese insulin-resistant OLETF rats. Am J Physiol Regul Integr Comp Physiol (2014) 0.95
Integrative neurobiology of metabolic diseases, neuroinflammation, and neurodegeneration. Front Neurosci (2015) 0.94
Association between variants of the leptin receptor gene (LEPR) and overweight: a systematic review and an analysis of the CoLaus study. PLoS One (2011) 0.92
Puberty in girls of the 21st century. J Pediatr Adolesc Gynecol (2012) 0.92
Addressing childhood obesity through increased physical activity. Nat Rev Endocrinol (2010) 0.92
The interactive effect of SIRT1 promoter region polymorphism on type 2 diabetes susceptibility in the North Indian population. PLoS One (2012) 0.91
Impact of yesterday's genes and today's diet and chemicals on tomorrow's women. J Pediatr Adolesc Gynecol (2009) 0.90
Control of Body Weight by Eating Behavior in Children. Front Pediatr (2015) 0.90
Exercise, weight loss, and changes in body composition in mice: phenotypic relationships and genetic architecture. Physiol Genomics (2010) 0.89
The clinical biochemistry of obesity. Clin Biochem Rev (2004) 0.89
Vascular transcriptional alterations produced by juvenile obesity in Ossabaw swine. Physiol Genomics (2013) 0.87
Exercise and diet affect quantitative trait loci for body weight and composition traits in an advanced intercross population of mice. Physiol Genomics (2012) 0.86
Developmental origins of obesity: programming of food intake or physical activity? Adv Exp Med Biol (2009) 0.85
Congenital and environmental factors associated with adipocyte dysregulation as defects of insulin resistance. Rev Diabet Stud (2007) 0.84
Hepatic steatosis development with four weeks of physical inactivity in previously active, hyperphagic OLETF rats. Am J Physiol Regul Integr Comp Physiol (2013) 0.84
Comparison with ancestral diets suggests dense acellular carbohydrates promote an inflammatory microbiota, and may be the primary dietary cause of leptin resistance and obesity. Diabetes Metab Syndr Obes (2012) 0.83
Physical Activity Transitions and Chronic Disease. Am J Lifestyle Med (2009) 0.82
Reduced carbohydrate diet to improve metabolic outcomes and decrease adiposity in obese peripubertal African American girls. J Pediatr Gastroenterol Nutr (2012) 0.82
The Mediterranean Lifestyle as a Non-Pharmacological and Natural Antioxidant for Healthy Aging. Antioxidants (Basel) (2015) 0.82
Genetic variants in potassium channels are associated with type 2 diabetes in a Mongolian population. J Diabetes (2012) 0.81
The myth of the female athlete triad. Br J Sports Med (2006) 0.81
Identification of genes whose expression is altered by obesity throughout the arterial tree. Physiol Genomics (2014) 0.81
Homeostasis in anorexia nervosa. Front Neurosci (2014) 0.80
Gene-Diet Interactions in Complex Disease: Current Findings and Relevance for Public Health. Curr Nutr Rep (2012) 0.80
Beyond thriftiness: independent and interactive effects of genetic and dietary factors on variations in fat deposition and distribution across populations. Am J Phys Anthropol (2011) 0.79
Counterregulation of insulin by leptin as key component of autonomic regulation of body weight. World J Diabetes (2014) 0.79
Pediatric obesity prevention: From naïve examination of energy imbalance towards strategies that influence the competition for nutrient resources among tissues. World J Clin Pediatr (2015) 0.78
Prenatal stress and stress coping style interact to predict metabolic risk in male rats. Endocrinology (2014) 0.78
A mathematical model of weight loss under total starvation: evidence against the thrifty-gene hypothesis. Dis Model Mech (2012) 0.78
Predictors of physical activity and sedentary behaviours among 11-16 year olds: Multilevel analysis of the 2013 Health Behaviour in School-aged Children (HBSC) study in Wales. BMC Public Health (2016) 0.78
Towards creating a superstimulus to normalise glucose metabolism in the prediabetic: a case-study in the feast-famine and activity-rest cycle. BMJ Case Rep (2012) 0.77
Exercise Mimetics: Impact on Health and Performance. Cell Metab (2016) 0.77
Inference of cross-level interaction between genes and contextual factors in a matched case-control metabolic syndrome study: a Bayesian approach. PLoS One (2013) 0.77
Low Dopamine D2 Receptor Increases Vulnerability to Obesity Via Reduced Physical Activity, Not Increased Appetitive Motivation. Biol Psychiatry (2015) 0.77
Complexity of type 2 diabetes mellitus data sets emerging from nutrigenomic research: a case for dimensionality reduction? Mutat Res (2007) 0.77
Renewed avenues through exercise muscle contractility and inflammatory status. ScientificWorldJournal (2012) 0.77
Hunter-gatherers have less famine than agriculturalists. Biol Lett (2014) 0.77
Sake Protein Supplementation Affects Exercise Performance and Biochemical Profiles in Power-Exercise-Trained Mice. Nutrients (2016) 0.76
Exercise and Regulation of Carbohydrate Metabolism. Prog Mol Biol Transl Sci (2015) 0.75
Eating habits modulate short term memory and epigenetical regulation of brain derived neurotrophic factor in hippocampus of low- and high running capacity rats. Brain Res Bull (2014) 0.75
Different effects of hyperlipidic diets in human lactation and adulthood: growth versus the development of obesity. Reprod Biol Endocrinol (2011) 0.75
Sustainability of a Curriculum-based Intervention on Dietary Behaviours and Physical Activity among Primary School Children in Trinidad and Tobago. West Indian Med J (2014) 0.75
Low cardio/respiratory fitness as an independent predictor of metabolic syndrome in Korean young men. Eur J Appl Physiol (2009) 0.75
A global evolutionary and metabolic analysis of human obesity gene risk variants. Gene (2017) 0.75
The dynamic plasticity of insulin production in β-cells. Mol Metab (2017) 0.75
Shared Dysregulation of Homeostatic Brain-Body Pathways in Depression and Type 2 Diabetes. Curr Diab Rep (2017) 0.75
Exercise training response heterogeneity: physiological and molecular insights. Diabetologia (2017) 0.75
Neurobiology of exercise. Obesity (Silver Spring) (2006) 3.39
Daily exercise increases hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima Fatty rats. Am J Physiol Gastrointest Liver Physiol (2008) 2.29
Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model. J Hepatol (2010) 2.09
A 2-wk reduction of ambulatory activity attenuates peripheral insulin sensitivity. J Appl Physiol (1985) (2009) 1.99
An obligation for primary care physicians to prescribe physical activity to sedentary patients to reduce the risk of chronic health conditions. Mayo Clin Proc (2002) 1.93
Control of the size of the human muscle mass. Annu Rev Physiol (2004) 1.83
Metabolic responses to reduced daily steps in healthy nonexercising men. JAMA (2008) 1.81
Cessation of daily exercise dramatically alters precursors of hepatic steatosis in Otsuka Long-Evans Tokushima Fatty (OLETF) rats. J Physiol (2008) 1.80
Inactivity induces increases in abdominal fat. J Appl Physiol (1985) (2006) 1.70
GSK-3beta negatively regulates skeletal myotube hypertrophy. Am J Physiol Cell Physiol (2002) 1.48
Daily exercise vs. caloric restriction for prevention of nonalcoholic fatty liver disease in the OLETF rat model. Am J Physiol Gastrointest Liver Physiol (2011) 1.41
Multiple signaling pathways mediate LIF-induced skeletal muscle satellite cell proliferation. Am J Physiol Cell Physiol (2002) 1.23
Cessation of daily wheel running differentially alters fat oxidation capacity in liver, muscle, and adipose tissue. J Appl Physiol (1985) (2008) 1.21
Elevated skeletal muscle irisin precursor FNDC5 mRNA in obese OLETF rats. Metabolism (2013) 1.19
Transcriptional profiling identifies extensive downregulation of extracellular matrix gene expression in sarcopenic rat soleus muscle. Physiol Genomics (2003) 1.17
Changes in skeletal muscle mitochondria in response to the development of type 2 diabetes or prevention by daily wheel running in hyperphagic OLETF rats. Am J Physiol Endocrinol Metab (2010) 1.15
Changes in visceral adipose tissue mitochondrial content with type 2 diabetes and daily voluntary wheel running in OLETF rats. J Physiol (2009) 1.15
Exercise-induced attenuation of obesity, hyperinsulinemia, and skeletal muscle lipid peroxidation in the OLETF rat. J Appl Physiol (1985) (2007) 1.15
Insulin-like growth factor 1 and muscle growth: implication for satellite cell proliferation. Proc Nutr Soc (2004) 1.14
Alterations in insulin receptor signalling in the rat epitrochlearis muscle upon cessation of voluntary exercise. J Physiol (2004) 1.12
Temporal alterations in protein signaling cascades during recovery from muscle atrophy. Am J Physiol Cell Physiol (2003) 1.12
Age-associated decrease in muscle precursor cell differentiation. Am J Physiol Cell Physiol (2005) 1.10
Selected Contribution: Identification of differentially expressed genes between young and old rat soleus muscle during recovery from immobilization-induced atrophy. J Appl Physiol (1985) (2003) 1.10
Effects of endurance exercise training, metformin, and their combination on adipose tissue leptin and IL-10 secretion in OLETF rats. J Appl Physiol (1985) (2012) 1.08
Expression profiling identifies dysregulation of myosin heavy chains IIb and IIx during limb immobilization in the soleus muscles of old rats. J Physiol (2003) 1.07
PGC-1α overexpression results in increased hepatic fatty acid oxidation with reduced triacylglycerol accumulation and secretion. Am J Physiol Gastrointest Liver Physiol (2012) 1.07
Physical activity maintains aortic endothelium-dependent relaxation in the obese type 2 diabetic OLETF rat. Am J Physiol Heart Circ Physiol (2010) 1.06
Daily physical activity enhances reactivity to insulin in skeletal muscle arterioles of hyperphagic Otsuka Long-Evans Tokushima Fatty rats. J Appl Physiol (1985) (2010) 1.06
Lack of regular physical exercise or too much inactivity. Curr Opin Clin Nutr Metab Care (2011) 1.05
Increased nuclear proteins in muscle satellite cells in aged animals as compared to young growing animals. Exp Gerontol (2004) 1.04
Sedentary death syndrome. Can J Appl Physiol (2004) 1.03
Lowering physical activity impairs glycemic control in healthy volunteers. Med Sci Sports Exerc (2012) 1.02
Forkhead transcription factor FoxO1 transduces insulin-like growth factor's signal to p27Kip1 in primary skeletal muscle satellite cells. J Cell Physiol (2003) 1.01
Physical inactivity is a disease. World Rev Nutr Diet (2005) 1.00
Early depression of Ankrd2 and Csrp3 mRNAs in the polyribosomal and whole tissue fractions in skeletal muscle with decreased voluntary running. J Appl Physiol (1985) (2012) 0.99
Sirt1 increases skeletal muscle precursor cell proliferation. Eur J Cell Biol (2008) 0.98
Responsiveness of cell signaling pathways during the failed 15-day regrowth of aged skeletal muscle. J Appl Physiol (1985) (2003) 0.98
Exercise training does not increase muscle FNDC5 protein or mRNA expression in pigs. Metabolism (2013) 0.97
Leukemia inhibitory factor restores the hypertrophic response to increased loading in the LIF(-/-) mouse. Cytokine (2006) 0.97
Dopamine D1 receptor modulation in nucleus accumbens lowers voluntary wheel running in rats bred to run high distances. Physiol Behav (2011) 0.97
Combining metformin and aerobic exercise training in the treatment of type 2 diabetes and NAFLD in OLETF rats. Am J Physiol Endocrinol Metab (2013) 0.96
Epicardial fat gene expression after aerobic exercise training in pigs with coronary atherosclerosis: relationship to visceral and subcutaneous fat. J Appl Physiol (1985) (2010) 0.94
Phenotypic and molecular differences between rats selectively bred to voluntarily run high vs. low nightly distances. Am J Physiol Regul Integr Comp Physiol (2013) 0.93
Physical activity opposes coronary vascular dysfunction induced during high fat feeding in mice. J Physiol (2012) 0.92
Age-dependent FOXO regulation of p27Kip1 expression via a conserved binding motif in rat muscle precursor cells. Am J Physiol Cell Physiol (2008) 0.92
FoxO3a preferentially induces p27Kip1 expression while impairing muscle precursor cell-cycle progression. Muscle Nerve (2008) 0.91
Sustained rise in triacylglycerol synthesis and increased epididymal fat mass when rats cease voluntary wheel running. J Physiol (2005) 0.91
Skeletal muscle IGF-binding protein-3 and -5 expressions are age, muscle, and load dependent. Am J Physiol Endocrinol Metab (2002) 0.90
Novel phosphorylation target in the serum response factor MADS box regulates alpha-actin transcription. Biochemistry (2003) 0.90
Differential changes in vascular mRNA levels between rat iliac and renal arteries produced by cessation of voluntary running. Exp Physiol (2012) 0.90
Perivascular fat alters reactivity of coronary artery: effects of diet and exercise. Med Sci Sports Exerc (2007) 0.89
Physiology of sedentary behavior and its relationship to health outcomes. Med Sci Sports Exerc (2015) 0.88
Fibroblast growth factor 2-stimulated proliferation is lower in muscle precursor cells from old rats. Exp Physiol (2009) 0.88
Increased mitochondrial glycerol-3-phosphate acyltransferase protein and enzyme activity in rat epididymal fat upon cessation of wheel running. Am J Physiol Endocrinol Metab (2005) 0.87
Postprandial leucine and insulin responses and toxicological effects of a novel whey protein hydrolysate-based supplement in rats. J Int Soc Sports Nutr (2012) 0.87
Vascular transcriptional alterations produced by juvenile obesity in Ossabaw swine. Physiol Genomics (2013) 0.87
Exercise and Omega-3 Polyunsaturated Fatty Acid Supplementation for the Treatment of Hepatic Steatosis in Hyperphagic OLETF Rats. J Nutr Metab (2011) 0.86
Anti-TNF treatment reduces rat skeletal muscle wasting in monocrotaline-induced cardiac cachexia. J Appl Physiol (1985) (2008) 0.85
Regrowth of skeletal muscle atrophied from inactivity. Med Sci Sports Exerc (2004) 0.85
IGF-I activates the mouse type IIb myosin heavy chain gene. Am J Physiol Cell Physiol (2009) 0.84
Hepatic steatosis development with four weeks of physical inactivity in previously active, hyperphagic OLETF rats. Am J Physiol Regul Integr Comp Physiol (2013) 0.84
Potential clinical translation of juvenile rodent inactivity models to study the onset of childhood obesity. Am J Physiol Regul Integr Comp Physiol (2012) 0.84
Muscle precursor cells isolated from aged rats exhibit an increased tumor necrosis factor- alpha response. Aging Cell (2009) 0.83
Treating NAFLD in OLETF rats with vigorous-intensity interval exercise training. Med Sci Sports Exerc (2015) 0.83
Understanding multi-organ pathology from insufficient exercise. J Appl Physiol (1985) (2011) 0.82
Insulin-like growth factor-induced transcriptional activity of the skeletal alpha-actin gene is regulated by signaling mechanisms linked to voltage-gated calcium channels during myoblast differentiation. Endocrinology (2003) 0.81
Effects of voluntary running on oxygen consumption, RQ, and energy expenditure during primary prevention of diet-induced obesity in C57BL/6N mice. J Appl Physiol (1985) (2012) 0.81
Exercise training prevents development of cardiac contractile dysfunction in hypertensive TG (mREN-2)27 rats. J Am Soc Hypertens (2010) 0.79
Ovariectomized Highly Fit Rats Are Protected against Diet-Induced Insulin Resistance. Med Sci Sports Exerc (2016) 0.79
Cocaine-induced locomotor activity in rats selectively bred for low and high voluntary running behavior. Psychopharmacology (Berl) (2014) 0.79
Comparing serum responses to acute feedings of an extensively hydrolyzed whey protein concentrate versus a native whey protein concentrate in rats: a metabolomics approach. Appl Physiol Nutr Metab (2013) 0.78
p27Kip1: a key regulator of skeletal muscle satellite cell proliferation. Clin Orthop Relat Res (2002) 0.78
Transient induction of cyclin A in loaded chicken skeletal muscle. J Appl Physiol (1985) (2003) 0.78
In response to Point:Counterpoint: "Satellite cell addition is/is not obligatory for skeletal muscle hypertrophy". J Appl Physiol (1985) (2007) 0.78
Sudden decrease in physical activity evokes adipocyte hyperplasia in 70- to 77-day-old rats but not 49- to 56-day-old rats. Am J Physiol Regul Integr Comp Physiol (2013) 0.78
Inactivity and inaction: we can't afford either. Arch Pediatr Adolesc Med (2003) 0.77
Novel epigenetic regulation of skeletal muscle myosin heavy chain genes. Focus on "Differential epigenetic modifications of histones at the myosin heavy chain genes in fast and slow skeletal muscle fibers and in response to muscle unloading". Am J Physiol Cell Physiol (2009) 0.77
Unlike myofibers, neuromuscular junctions remain stable during prolonged muscle unloading. J Neurol Sci (2003) 0.76
Voluntary Running Attenuates Metabolic Dysfunction in Ovariectomized Low-Fit Rats. Med Sci Sports Exerc (2016) 0.75
Physical activity and dietary intervention for chronic diseases: a quick fix after all? J Appl Physiol (1985) (2006) 0.75
Exercise Training As A Mitigator Of Liver Fibrosis In Western Diet Fed OLETF Rats: 1783 Board #3 June 2, 1: 00 PM - 3: 00 PM. Med Sci Sports Exerc (2016) 0.75
Mechanisms Associated with Physical Activity Behavior: Insights from Rodent Experiments. Exerc Sport Sci Rev (2017) 0.75
Effects Of Intrinsic Aerobic Capacity And Ovariectomy on Voluntary Wheel Running and Mid-brain Dopamine Signaling: 2935 June 3 2: 15 PM - 2: 30 PM. Med Sci Sports Exerc (2016) 0.75