Published in J Bone Miner Res on December 01, 2003
High dimensional endophenotype ranking in the search for major depression risk genes. Biol Psychiatry (2011) 2.23
Meta-analysis of genome-wide scans provides evidence for sex- and site-specific regulation of bone mass. J Bone Miner Res (2007) 1.82
Genetics of microstructure of cerebral white matter using diffusion tensor imaging. Neuroimage (2010) 1.70
Molecular genetic studies of gene identification for osteoporosis: a 2004 update. J Bone Miner Res (2006) 1.52
Variation in genes involved in the RANKL/RANK/OPG bone remodeling pathway are associated with bone mineral density at different skeletal sites in men. Hum Genet (2005) 1.30
Analysis of genetic variability and whole genome linkage of whole-brain, subcortical, and ependymal hyperintense white matter volume. Stroke (2009) 1.24
Identification of mouse Duffy antigen receptor for chemokines (Darc) as a BMD QTL gene. Genome Res (2007) 1.21
Whole brain and regional hyperintense white matter volume and blood pressure: overlap of genetic loci produced by bivariate, whole-genome linkage analyses. Stroke (2010) 1.09
Genome-wide approaches for identifying genetic risk factors for osteoporosis. Genome Med (2013) 1.09
Genetic analysis of cortical thickness and fractional anisotropy of water diffusion in the brain. Front Neurosci (2011) 1.09
Arguments for the sake of endophenotypes: examining common misconceptions about the use of endophenotypes in psychiatric genetics. Am J Med Genet B Neuropsychiatr Genet (2014) 1.08
A genome-wide linkage scan for bone mineral density in an extended sample: evidence for linkage on 11q23 and Xq27. J Med Genet (2004) 1.00
Mutations in the insulin-like factor 3 receptor are associated with osteoporosis. J Bone Miner Res (2008) 0.96
Quantitative trait loci, genes, and polymorphisms that regulate bone mineral density in mouse. Genomics (2009) 0.96
Refined QTLs of osteoporosis-related traits by linkage analysis with genome-wide SNPs: Framingham SHARe. Bone (2010) 0.95
Identification of a role for the ARHGEF3 gene in postmenopausal osteoporosis. Am J Hum Genet (2008) 0.94
A functional haplotype in EIF2AK3, an ER stress sensor, is associated with lower bone mineral density. J Bone Miner Res (2012) 0.93
CD38 is associated with premenopausal and postmenopausal bone mineral density and postmenopausal bone loss. J Bone Miner Metab (2006) 0.92
Genetic loci affecting bone structure and strength in inbred COP and DA rats. Bone (2007) 0.92
Bone mineral density variation in men is influenced by sex-specific and non sex-specific quantitative trait loci. Bone (2009) 0.90
Linkage screen for BMD phenotypes in male and female COP and DA rat strains. J Bone Miner Res (2008) 0.89
Identification of quantitative trait loci affecting body composition in a mouse intercross. Proc Natl Acad Sci U S A (2006) 0.89
Assessment of linkage and association of 13 genetic loci with bone mineral density. J Bone Miner Metab (2006) 0.88
Genetic influences on bone loss in the San Antonio Family Osteoporosis study. Osteoporos Int (2008) 0.87
Sex-specific genetic loci for femoral neck bone mass and strength identified in inbred COP and DA rats. J Bone Miner Res (2008) 0.87
Quantitative trait locus on chromosome 1q influences bone loss in young Mexican American adults. Calcif Tissue Int (2008) 0.87
Quantitative trait loci modulate vertebral morphology and mechanical properties in a population of 18-month-old genetically heterogeneous mice. Bone (2006) 0.85
Vitamin D-binding protein gene microsatellite polymorphism influences BMD and risk of fractures in men. Osteoporos Int (2007) 0.83
Choice of study phenotype in osteoporosis genetic research. J Bone Miner Metab (2009) 0.82
Cortical bone health shows significant linkage to chromosomes 2p, 3p, and 17q in 10-year-old children. Bone (2011) 0.81
A whole genome linkage scan for QTLs underlying peak bone mineral density. Osteoporos Int (2007) 0.80
A common variant in fibroblast growth factor binding protein 1 (FGFBP1) is associated with bone mineral density and influences gene expression in vitro. Bone (2010) 0.77
Association of PLOD1 polymorphisms with bone mineral density in a population-based study of women from the UK. Osteoporos Int (2006) 0.77
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes. Nat Genet (2007) 11.09
Genetic Analysis Workshop 17 mini-exome simulation. BMC Proc (2011) 9.16
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences. Nature (2007) 7.91
Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. JAMA (2009) 6.80
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
Diabetic autonomic neuropathy. Diabetes Care (2003) 6.59
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. Am J Hum Genet (2004) 5.02
A genome-wide association study of alcohol dependence. Proc Natl Acad Sci U S A (2010) 4.94
Genomic inflation factors under polygenic inheritance. Eur J Hum Genet (2011) 4.89
Inhibitors of factor VIII in black patients with hemophilia. N Engl J Med (2009) 4.82
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
Proton pump inhibitor and histamine 2 receptor antagonist use and vitamin B12 deficiency. JAMA (2013) 4.67
A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection. Science (2008) 4.50
Deep resequencing reveals excess rare recent variants consistent with explosive population growth. Nat Commun (2010) 4.39
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Nat Genet (2011) 4.04
Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies. Lancet Neurol (2012) 3.93
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genet (2011) 3.92
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
Telomere length is paternally inherited and is associated with parental lifespan. Proc Natl Acad Sci U S A (2007) 3.67
Cortical thickness or grey matter volume? The importance of selecting the phenotype for imaging genetics studies. Neuroimage (2009) 3.66
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest (2008) 3.51
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet (2012) 3.40
From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene. Proc Natl Acad Sci U S A (2008) 3.39
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
A comprehensive linkage analysis for myocardial infarction and its related risk factors. Nat Genet (2002) 3.19
NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. PLoS Genet (2009) 3.18
The association between cardiovascular autonomic neuropathy and mortality in individuals with diabetes: a meta-analysis. Diabetes Care (2003) 3.18
Physical activity and the association of common FTO gene variants with body mass index and obesity. Arch Intern Med (2008) 3.15
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2. Nat Genet (2011) 3.02
Genome-wide association study of alcohol dependence implicates a region on chromosome 11. Alcohol Clin Exp Res (2010) 2.99
The Next PAGE in understanding complex traits: design for the analysis of Population Architecture Using Genetics and Epidemiology (PAGE) Study. Am J Epidemiol (2011) 2.98
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Neurocognitive endophenotypes in a multiplex multigenerational family study of schizophrenia. Am J Psychiatry (2007) 2.84
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
FTO genotype is associated with phenotypic variability of body mass index. Nature (2012) 2.77
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet (2011) 2.73
Metabolic syndrome and salt sensitivity of blood pressure in non-diabetic people in China: a dietary intervention study. Lancet (2009) 2.73
Poor sleep is associated with impaired cognitive function in older women: the study of osteoporotic fractures. J Gerontol A Biol Sci Med Sci (2006) 2.73
Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med (2013) 2.73
CUBN is a gene locus for albuminuria. J Am Soc Nephrol (2011) 2.70
The genetic response to short-term interventions affecting cardiovascular function: rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study. Am Heart J (2008) 2.61
Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke. Ann Neurol (2009) 2.55
Fenofibrate effect on triglyceride and postprandial response of apolipoprotein A5 variants: the GOLDN study. Arterioscler Thromb Vasc Biol (2007) 2.54
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet (2012) 2.53
Genetic epidemiology of insulin resistance and visceral adiposity. The IRAS Family Study design and methods. Ann Epidemiol (2003) 2.51
Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis. Hum Mol Genet (2006) 2.49
Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus. Proc Natl Acad Sci U S A (2002) 2.47
Probable migraine with visual aura and risk of ischemic stroke: the stroke prevention in young women study. Stroke (2007) 2.43
Genetic and environmental factors influencing the human factor H plasma levels. Immunogenetics (2004) 2.43
Neuroimaging endophenotypes: strategies for finding genes influencing brain structure and function. Hum Brain Mapp (2007) 2.36
Genomic evaluations with many more genotypes. Genet Sel Evol (2011) 2.34
Associations between genetic variants in the NOS1AP (CAPON) gene and cardiac repolarization in the old order Amish. Hum Hered (2007) 2.26
The role of GABRA2 in risk for conduct disorder and alcohol and drug dependence across developmental stages. Behav Genet (2006) 2.26
High dimensional endophenotype ranking in the search for major depression risk genes. Biol Psychiatry (2011) 2.23
Reconstructing an ancestral mammalian immune supercomplex from a marsupial major histocompatibility complex. PLoS Biol (2006) 2.17
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet (2010) 2.15
Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study. PLoS Genet (2011) 2.13
Linkage and linkage disequilibrium mapping of ERP and EEG phenotypes. Biol Psychol (2002) 2.08
Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study. Obesity (Silver Spring) (2009) 2.07
Gender difference in blood pressure responses to dietary sodium intervention in the GenSalt study. J Hypertens (2009) 2.06
Factors of insulin resistance syndrome--related phenotypes are linked to genetic locations on chromosomes 6 and 7 in nondiabetic mexican-americans. Diabetes (2002) 2.06
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet (2012) 2.05
The -256T>C polymorphism in the apolipoprotein A-II gene promoter is associated with body mass index and food intake in the genetics of lipid lowering drugs and diet network study. Clin Chem (2007) 2.03
Determinants of coronary artery and aortic calcification in the Old Order Amish. Circulation (2007) 2.02