Published in Ann N Y Acad Sci on November 01, 2003
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet (2013) 4.62
Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis. Nat Genet (2007) 4.22
MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction. Nat Genet (2005) 2.32
Smoking and two human leukocyte antigen genes interact to increase the risk for multiple sclerosis. Brain (2011) 2.24
Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes. Science (2009) 1.90
Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes. Diabetes (2002) 1.89
Changes to anti-JCV antibody levels in a Swedish national MS cohort. J Neurol Neurosurg Psychiatry (2013) 1.63
Low serum levels of vitamin D in idiopathic inflammatory myopathies. Ann Rheum Dis (2012) 1.59
Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis. Neurology (2014) 1.54
Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course. Mult Scler (2010) 1.46
Lack of replication of interaction between EBNA1 IgG and smoking in risk for multiple sclerosis. Neurology (2012) 1.42
Recombinant Fabs of human monoclonal antibodies specific to the middle epitope of GAD65 inhibit type 1 diabetes-specific GAD65Abs. Diabetes (2003) 1.23
Lack of support for association between the KIF1B rs10492972[C] variant and multiple sclerosis. Nat Genet (2010) 1.16
The lack of anti-idiotypic antibodies, not the presence of the corresponding autoantibodies to glutamate decarboxylase, defines type 1 diabetes. Proc Natl Acad Sci U S A (2008) 1.15
High-resolution quantitative trait locus analysis reveals multiple diabetes susceptibility loci mapped to intervals<800 kb in the species-conserved Niddm1i of the GK rat. Genetics (2006) 1.13
Heredity of hypospadias and the significance of low birth weight. J Urol (2002) 1.12
Activating transcription factor 3: a hormone responsive gene in the etiology of hypospadias. Eur J Endocrinol (2008) 1.12
Soluble IL7Rα potentiates IL-7 bioactivity and promotes autoimmunity. Proc Natl Acad Sci U S A (2013) 1.07
A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis. Eur J Hum Genet (2009) 1.05
Loss-of-function variants of the filaggrin gene are associated with atopic eczema and associated phenotypes in Swedish families. Acta Derm Venereol (2008) 1.03
A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes. Cell Metab (2011) 1.03
The valine allele of the V89L polymorphism in the 5-alpha-reductase gene confers a reduced risk for hypospadias. J Clin Endocrinol Metab (2005) 1.00
IL-22RA2 associates with multiple sclerosis and macrophage effector mechanisms in experimental neuroinflammation. J Immunol (2010) 0.99
Confirmation of association between multiple sclerosis and CYP27B1. Eur J Hum Genet (2010) 0.99
Risk conferred by HLA-DR and DQ for type 1 diabetes in 0-35-year age group in Sweden. Ann N Y Acad Sci (2008) 0.98
Multiple factors affect the loss of measurable C-peptide over 6 years in newly diagnosed 15- to 35-year-old diabetic subjects. J Diabetes Complications (2007) 0.93
Decline of C-peptide during the first year after diagnosis of Type 1 diabetes in children and adolescents. Diabetes Res Clin Pract (2013) 0.93
Development of heart block in children of SSA/SSB-autoantibody-positive women is associated with maternal age and displays a season-of-birth pattern. Ann Rheum Dis (2011) 0.93
Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles. PLoS One (2013) 0.92
Importance of human leukocyte antigen (HLA) class I and II alleles on the risk of multiple sclerosis. PLoS One (2012) 0.92
GAD65 antibody epitope patterns of type 1.5 diabetic patients are consistent with slow-onset autoimmune diabetes. Diabetes Care (2002) 0.90
A role for VAV1 in experimental autoimmune encephalomyelitis and multiple sclerosis. Sci Transl Med (2009) 0.90
Variation in the BMP2 gene: bone mineral density and ultrasound in young adult and elderly women. Calcif Tissue Int (2007) 0.90
Risk factors for hypospadias in the estrogen receptor 2 gene. J Clin Endocrinol Metab (2007) 0.89
Separately inherited defects in insulin exocytosis and beta-cell glucose metabolism contribute to type 2 diabetes. Diabetes (2006) 0.89
Immune-mediated beta-cell destruction in vitro and in vivo-A pivotal role for galectin-3. Biochem Biophys Res Commun (2006) 0.87
Prevalence of stroke and vascular risk factors among first-degree relatives of stroke patients and control subjects. A prospective consecutive study. Cerebrovasc Dis (2005) 0.87
The expression of VEGF-A is down regulated in peripheral blood mononuclear cells of patients with secondary progressive multiple sclerosis. PLoS One (2011) 0.86
Ischaemic stroke in hypertensive patients is associated with variations in the PDE4D genome region. Eur J Hum Genet (2008) 0.86
The DQB1 *03:02 HLA haplotype is associated with increased risk of chronic pain after inguinal hernia surgery and lumbar disc herniation. Pain (2012) 0.86
Genetic association with ERAP1 in psoriasis is confined to disease onset after puberty and not dependent on HLA-C*06. J Invest Dermatol (2012) 0.86
Two HLA class I genes independently associated with multiple sclerosis. J Neuroimmunol (2010) 0.85
A large-sample assessment of possible association between ischaemic stroke and rs12188950 in the PDE4D gene. Eur J Hum Genet (2012) 0.85
Serum levels of LIGHT in MS. Mult Scler (2012) 0.84
Interaction and association analysis of a type 1 diabetes susceptibility locus on chromosome 5q11-q13 and the 7q32 chromosomal region in Scandinavian families. Diabetes (2004) 0.83
No mutations in the BACH1 gene in BRCA1 and BRCA2 negative breast-cancer families linked to 17q22. Int J Cancer (2002) 0.83
Alterations in KLRB1 gene expression and a Scandinavian multiple sclerosis association study of the KLRB1 SNP rs4763655. Eur J Hum Genet (2011) 0.81
The interleukin 23 receptor gene in multiple sclerosis: a case-control study. J Neuroimmunol (2008) 0.81
Genetic regulation of bone traits is influenced by sex and reciprocal cross in F(2) progeny from GK and F344 rats. J Bone Miner Res (2009) 0.81
Association between the transmembrane region polymorphism of MHC class I chain related gene-A and type 1 diabetes mellitus in Sweden. Hum Immunol (2003) 0.81
Comparative sequence analysis of the non-protein-coding mitochondrial DNA of inbred rat strains. PLoS One (2009) 0.81
Association of genetic markers with CSF oligoclonal bands in multiple sclerosis patients. PLoS One (2013) 0.80
Crohn's disease associated CARD15 (NOD2) variants are not involved in the susceptibility to type 1 diabetes. Mol Genet Metab (2005) 0.80
New loci regulating rat myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis. J Immunol (2003) 0.80
Altered transcapillary escape of albumin and microalbuminuria reflects two different pathogenetic mechanisms. Diabetes (2005) 0.80
Variation in the bone morphogenetic protein-2 gene: effects on fat and lean body mass in young and elderly women. Eur J Endocrinol (2008) 0.79
Positional cloning of the Igl genes controlling rheumatoid factor production and allergic bronchitis in rats. Proc Natl Acad Sci U S A (2008) 0.79
High resolution mapping of an arthritis susceptibility locus on rat chromosome 4, and characterization of regulated phenotypes. Hum Mol Genet (2003) 0.78
Are BIC (miR-155) polymorphisms associated with eczema susceptibility? Acta Derm Venereol (2013) 0.78
Nerve compression induces activating transcription factor 3 in neurons and Schwann cells in diabetic rats. Neuroreport (2008) 0.78
Variations in apolipoprotein D and sigma non-opioid intracellular receptor 1 genes with relation to risk, severity and outcome of ischemic stroke. BMC Neurol (2014) 0.78
The effect of polymorphisms in the renin-angiotensin-aldosterone system on diabetic nephropathy risk. J Diabetes Complications (2008) 0.78
Lack of association between neuropeptide S receptor 1 gene (NPSR1) and eczema in five European populations. Acta Derm Venereol (2009) 0.78
Interleukin 18 receptor 1 expression distinguishes patients with multiple sclerosis. Mult Scler (2010) 0.78
Identification of candidate gene regions in the rat by co-localization of QTLs for bone density, size, structure and strength. PLoS One (2011) 0.78
Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis. PLoS One (2012) 0.78
Retrovirus-like long-terminal repeat DQ-LTR13 and genetic susceptibility to type 1 diabetes and autoimmune Addison's disease. Diabetes (2005) 0.77
Genome-wide linkage analysis for hypospadias susceptibility genes. J Urol (2004) 0.77
Causal Effect of Genetic Variants Associated With Body Mass Index on Multiple Sclerosis Susceptibility. Am J Epidemiol (2017) 0.77
Genetic loci for bone architecture determined by three-dimensional CT in crosses with the diabetic GK rat. Bone (2010) 0.77
Islet cell antibodies (ICA) identify autoimmunity in children with new onset diabetes mellitus negative for other islet cell antibodies. Pediatr Diabetes (2013) 0.77
HTR1A a novel type 1 diabetes susceptibility gene on chromosome 5p13-q13. PLoS One (2012) 0.76
Variation in the PTH2R gene is associated with age-related degenerative changes in the lumbar spine. J Bone Miner Metab (2013) 0.76
A new susceptibility locus for hypospadias on chromosome 7q32.2-q36.1. Hum Genet (2008) 0.76
Linkage study of embryopathy-polygenic inheritance of diabetes-induced skeletal malformations in the rat. Reprod Toxicol (2012) 0.75
Genome-wide linkage analysis in families with infantile hypertrophic pyloric stenosis indicates novel susceptibility loci. J Hum Genet (2011) 0.75
Complex aetiology of an apparently Mendelian form of mental retardation. BMC Med Genet (2008) 0.75
Coxsackie virus B antibodies are increased in HLA DR3-MICA5.1 positive type 1 diabetes patients in the Linköping region of Sweden. Hum Immunol (2003) 0.75
No evidence of type 1 diabetes susceptibility genes in the region centromeric of the HLA complex. Hum Immunol (2003) 0.75
No evidence for a familial breast cancer susceptibility gene at chromosome 13q21 in Swedish breast cancer families. Int J Cancer (2002) 0.75
Linkage Analysis: An Important Tool for Pre-Clinical Alport's Diagnosis. Saudi J Kidney Dis Transpl (2007) 0.75
Association analysis in type 1 diabetes of the PRSS16 gene encoding a thymus-specific serine protease. Hum Immunol (2007) 0.75
A region close to Tp53 shows LOH in familial breast cancer. Int J Mol Med (2002) 0.75
No influence on disease progression of non-HLA susceptibility genes in MS. J Neuroimmunol (2011) 0.75