Published in Am J Respir Med on January 01, 2003
Aryl hydrocarbon receptor-deficient mice develop heightened inflammatory responses to cigarette smoke and endotoxin associated with rapid loss of the nuclear factor-kappaB component RelB. Am J Pathol (2007) 1.72
Nuclear translocation of p65 NF-kappaB is sufficient for VCAM-1, but not ICAM-1, expression in TNF-stimulated smooth muscle cells: Differential requirement for PARP-1 expression and interaction. Cell Signal (2007) 1.35
Lipid peroxidation inhibition blunts nuclear factor-kappaB activation, reduces skeletal muscle degeneration, and enhances muscle function in mdx mice. Am J Pathol (2006) 1.24
Azithromycin reduces spontaneous and induced inflammation in DeltaF508 cystic fibrosis mice. Respir Res (2006) 1.12
Changing the burden of COPD mortality. Int J Chron Obstruct Pulmon Dis (2006) 1.11
Dysfunction of Nrf-2 in CF epithelia leads to excess intracellular H2O2 and inflammatory cytokine production. PLoS One (2008) 1.08
Airway epithelial NF-κB activation promotes allergic sensitization to an innocuous inhaled antigen. Am J Respir Cell Mol Biol (2010) 1.08
Targeting inflammation to prevent bronchopulmonary dysplasia: can new insights be translated into therapies? Pediatrics (2011) 1.08
Inhibiting NF-κB in the developing lung disrupts angiogenesis and alveolarization. Am J Physiol Lung Cell Mol Physiol (2012) 1.04
The 3020insC Allele of NOD2 Predisposes to Cancers of Multiple Organs. Hered Cancer Clin Pract (2005) 1.04
Aspergillus fumigatus-induced interleukin-8 synthesis by respiratory epithelial cells is controlled by the phosphatidylinositol 3-kinase, p38 MAPK, and ERK1/2 pathways and not by the toll-like receptor-MyD88 pathway. J Biol Chem (2008) 1.03
Polyphenols in the treatment of inflammatory bowel disease and acute pancreatitis. Gut (2006) 1.03
Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells. Mol Cancer Ther (2008) 1.02
Multiple anti-inflammatory pathways triggered by resveratrol lead to amelioration of staphylococcal enterotoxin B-induced lung injury. Br J Pharmacol (2012) 1.01
NFkappaB is persistently activated in continuously stimulated human neutrophils. Mol Med (2007) 0.97
Distinct functions of airway epithelial nuclear factor-kappaB activity regulate nitrogen dioxide-induced acute lung injury. Am J Respir Cell Mol Biol (2009) 0.93
Innate immune responses in house dust mite allergy. ISRN Allergy (2013) 0.92
Anti-inflammatory effects of adrenomedullin on acute lung injury induced by Carrageenan in mice. Mediators Inflamm (2012) 0.91
Role of type 2 deiodinase in response to acute lung injury (ALI) in mice. Proc Natl Acad Sci U S A (2011) 0.89
Protective Effect of the Fruit Hull of Gleditsia sinensis on LPS-Induced Acute Lung Injury Is Associated with Nrf2 Activation. Evid Based Complement Alternat Med (2012) 0.87
Inhibition of NFkappaB by the natural product Withaferin A in cellular models of Cystic Fibrosis inflammation. J Inflamm (Lond) (2009) 0.86
Galangin dampens mice lipopolysaccharide-induced acute lung injury. Inflammation (2014) 0.85
Mechanism of telomerase activation by v-Rel and its contribution to transformation. J Virol (2006) 0.84
Berberine attenuates cigarette smoke-induced acute lung inflammation. Inflammation (2013) 0.83
Suppressing NF-κB and NKRF Pathways by Induced Pluripotent Stem Cell Therapy in Mice with Ventilator-Induced Lung Injury. PLoS One (2013) 0.81
Stevioside protects LPS-induced acute lung injury in mice. Inflammation (2013) 0.80
Therapeutic effect of C-phycocyanin extracted from blue green algae in a rat model of acute lung injury induced by lipopolysaccharide. Evid Based Complement Alternat Med (2013) 0.80
DNA-dependent protein kinase inhibition blocks asthma in mice and modulates human endothelial and CD4⁺ T-cell function without causing severe combined immunodeficiency. J Allergy Clin Immunol (2014) 0.79
Epigenetics and chromatin remodeling play a role in lung disease. Tanaffos (2011) 0.75
Increased expression of A Proliferation-inducing Ligand (APRIL) in lung leukocytes and alveolar epithelial cells in COPD patients with non small cell lung cancer: a possible link between COPD and lung cancer? Multidiscip Respir Med (2016) 0.75
Analysis of the activation routes induced by different metal oxide nanoparticles on human lung epithelial cells. Future Sci OA (2016) 0.75
Mitochondrial CaMKII inhibition in airway epithelium protects against allergic asthma. JCI Insight (2017) 0.75
Transfer factor for carbon monoxide in patients with COPD and diabetes: results from the German COSYCONET cohort. Respir Res (2017) 0.75
Protective Effects of Apigenin Against Paraquat-Induced Acute Lung Injury in Mice. Inflammation (2016) 0.75
Pathogen-host interactions in Pseudomonas aeruginosa pneumonia. Am J Respir Crit Care Med (2005) 3.52
Duration and intensity of NF-kappaB activity determine the severity of endotoxin-induced acute lung injury. J Immunol (2006) 2.96
Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway. J Clin Invest (2007) 2.36
Selective cyclooxygenase-1 and -2 inhibitors each increase allergic inflammation and airway hyperresponsiveness in mice. Am J Respir Crit Care Med (2002) 2.17
Airway epithelium controls lung inflammation and injury through the NF-kappa B pathway. J Immunol (2007) 2.07
Macrophages are necessary for maximal nuclear factor-kappa B activation in response to endotoxin. Am J Respir Cell Mol Biol (2002) 2.05
Monocytes are potent facilitators of alveolar neutrophil emigration during lung inflammation: role of the CCL2-CCR2 axis. J Immunol (2003) 1.95
Resident alveolar macrophages are replaced by recruited monocytes in response to endotoxin-induced lung inflammation. Am J Respir Cell Mol Biol (2006) 1.70
NADPH oxidase limits innate immune responses in the lungs in mice. PLoS One (2010) 1.69
Targeted immunomodulation of the NF-kappaB pathway in airway epithelium impacts host defense against Pseudomonas aeruginosa. J Immunol (2006) 1.62
Role of resident alveolar macrophages in leukocyte traffic into the alveolar air space of intact mice. Am J Physiol Lung Cell Mol Physiol (2002) 1.51
Macrophage Turnover Kinetics in the Lungs of Mice Infected with Streptococcus pneumoniae. Am J Respir Cell Mol Biol (2007) 1.42
Involvement of cyclooxygenase-2 and prostaglandins in the molecular pathogenesis of inflammatory lung diseases. Am J Physiol Lung Cell Mol Physiol (2006) 1.40
p47phox deficiency impairs NF-kappa B activation and host defense in Pseudomonas pneumonia. J Immunol (2004) 1.36
Selective I kappa B kinase expression in airway epithelium generates neutrophilic lung inflammation. J Immunol (2003) 1.34
Bacterial clearance of Pseudomonas aeruginosa is enhanced by the inhibition of COX-2. Eur J Immunol (2007) 1.32
Prevalence of type 2 diabetes in patients with obstructive sleep apnea in a multi-ethnic sample. J Clin Sleep Med (2009) 1.29
An improved LC-MS/MS method for the quantification of prostaglandins E(2) and D(2) production in biological fluids. Anal Biochem (2007) 1.25
Pneumolysin-induced lung injury is independent of leukocyte trafficking into the alveolar space. J Immunol (2004) 1.23
Importance of CXC chemokine receptor 2 in alveolar neutrophil and exudate macrophage recruitment in response to pneumococcal lung infection. Infect Immun (2010) 1.23
E3 ubiquitin ligase Cblb regulates the acute inflammatory response underlying lung injury. Nat Med (2007) 1.22
CCR2-positive monocytes recruited to inflamed lungs downregulate local CCL2 chemokine levels. Am J Physiol Lung Cell Mol Physiol (2004) 1.18
Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase beta. J Virol (2005) 1.16
Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation. Am J Respir Crit Care Med (2013) 1.15
Intratracheal administration of liposomal clodronate accelerates alveolar macrophage reconstitution following fetal liver transplantation. J Leukoc Biol (2004) 1.11
NIK is involved in nucleosomal regulation by enhancing histone H3 phosphorylation by IKKalpha. J Biol Chem (2006) 1.08
Nuclear factor kappa B is a promising therapeutic target in inflammatory lung disease. Curr Drug Targets (2006) 1.05
Dangkwisoo-san, an herbal medicinal formula, ameliorates acute lung inflammation via activation of Nrf2 and suppression of NF-κB. J Ethnopharmacol (2012) 1.04
Inducible binding of PU.1 and interacting proteins to the Toll-like receptor 4 promoter during endotoxemia. Am J Physiol Lung Cell Mol Physiol (2005) 1.04
Functional PU.1 in macrophages has a pivotal role in NF-κB activation and neutrophilic lung inflammation during endotoxemia. Blood (2011) 1.03
NF-kappaB regulates thrombin-induced ICAM-1 gene expression in cooperation with NFAT by binding to the intronic NF-kappaB site in the ICAM-1 gene. Physiol Genomics (2009) 1.03
Transcriptional regulation of the cyclooxygenase-2 gene in macrophages by PU.1. J Biol Chem (2003) 1.01
Induction and function of lipocalin prostaglandin D synthase in host immunity. J Immunol (2007) 1.01
Myeloid cells control termination of lung inflammation through the NF-kappaB pathway. Am J Physiol Lung Cell Mol Physiol (2008) 1.01
Protective role of reactive oxygen species in endotoxin-induced lung inflammation through modulation of IL-10 expression. J Immunol (2012) 1.00
Bioluminescent detection of endotoxin effects on HIV-1 LTR-driven transcription in vivo. J Histochem Cytochem (2003) 0.99
Local delivery of GM-CSF protects mice from lethal pneumococcal pneumonia. J Immunol (2011) 0.98
Tumor necrosis factor-alpha-mediated suppression of adipocyte apolipoprotein E gene transcription: primary role for the nuclear factor (NF)-kappaB pathway and NFkappaB p50. Endocrinology (2008) 0.96
The novel role of IL-7 ligation to IL-7 receptor in myeloid cells of rheumatoid arthritis and collagen-induced arthritis. J Immunol (2013) 0.95
Regulation of macrophage cyclooxygenase-2 gene expression by modifications of histone H3. Am J Physiol Lung Cell Mol Physiol (2003) 0.95
Systemic nf-kappaB activation in a transgenic mouse model of acute pancreatitis. J Surg Res (2003) 0.95
Endotoxin potentiates lung injury in cerulein-induced pancreatitis. Am J Surg (2003) 0.95
Modulation of endotoxin-induced NF-kappa B activation in lung and liver through TNF type 1 and IL-1 receptors. Am J Physiol Lung Cell Mol Physiol (2002) 0.93
Competitive enzymatic interactions determine the relative amounts of prostaglandins E2 and D2. J Pharmacol Exp Ther (2011) 0.92
Map kinase phosphatase 5 protects against sepsis-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol (2012) 0.90
Recruited alveolar macrophages, in response to airway epithelial-derived monocyte chemoattractant protein 1/CCl2, regulate airway inflammation and remodeling in allergic asthma. Am J Respir Cell Mol Biol (2015) 0.89
Dendritic cell depletion and repopulation in the lung after irradiation and bone marrow transplantation in mice. Am J Respir Cell Mol Biol (2010) 0.89
Lipopolysaccharide-dependent interaction between PU.1 and c-Jun determines production of lipocalin-type prostaglandin D synthase and prostaglandin D2 in macrophages. Am J Physiol Lung Cell Mol Physiol (2009) 0.88
Yin Yang 1 enhances cyclooxygenase-2 gene expression in macrophages. Am J Physiol Lung Cell Mol Physiol (2007) 0.88
Hepatic cryoablation-induced multisystem injury: bioluminescent detection of NF-kappaB activation in a transgenic mouse model. J Gastrointest Surg (2002) 0.88
Protective Effect of the Fruit Hull of Gleditsia sinensis on LPS-Induced Acute Lung Injury Is Associated with Nrf2 Activation. Evid Based Complement Alternat Med (2012) 0.87
Pivotal role of reactive oxygen species in differential regulation of lipopolysaccharide-induced prostaglandins production in macrophages. Mol Pharmacol (2012) 0.86
NF-kappaB-inducing kinase regulates cyclooxygenase 2 gene expression in macrophages by phosphorylation of PU.1. J Immunol (2007) 0.85
Regulation of cyclooxygenase-2 expression by small GTPase Rac2 in bone marrow macrophages. Am J Physiol Lung Cell Mol Physiol (2007) 0.84
ent-kaur-16-en-19-oic Acid, isolated from the roots of Aralia continentalis, induces activation of Nrf2. J Ethnopharmacol (2011) 0.83
PU.1 regulates cathepsin S expression in professional APCs. J Immunol (2006) 0.83
Therapeutic Effect of the Tuber of Alisma orientale on Lipopolysaccharide-Induced Acute Lung Injury. Evid Based Complement Alternat Med (2013) 0.83
Lipopolysaccharide-induced expression of microsomal prostaglandin E synthase-1 mediates late-phase PGE2 production in bone marrow derived macrophages. PLoS One (2012) 0.83
Endotoxin induced peritonitis elicits monocyte immigration into the lung: implications on alveolar space inflammatory responsiveness. Respir Res (2006) 0.82
Role for the guanine nucleotide exchange factor phosphatidylinositol-3,4,5-trisphosphate-dependent rac exchanger 1 in platelet secretion and aggregation. Arterioscler Thromb Vasc Biol (2011) 0.81
Anthrax lethal factor activates K(+) channels to induce IL-1β secretion in macrophages. J Immunol (2011) 0.81
Activation of nuclear factor kappa B and severe hepatic necrosis may mediate systemic inflammation in choline-deficient/ethionine-supplemented diet-induced pancreatitis. Pancreas (2006) 0.81
Nrf2 is essential for the expression of lipocalin-prostaglandin D synthase induced by prostaglandin D2. Free Radic Biol Med (2013) 0.80
Development of a nomogram for identification of asthma among adults in epidemiologic studies. Ann Allergy Asthma Immunol (2010) 0.79
Method development and validation for ultra-high pressure liquid chromatography/tandem mass spectrometry determination of multiple prostanoids in biological samples. J AOAC Int (2013) 0.79
Genetic determination of the role of PU.1 in macrophage gene expression. Biochem Biophys Res Commun (2008) 0.78
Inhibitory kappaB kinase 2 activates airway epithelial cells to stimulate bone marrow macrophages. Am J Respir Cell Mol Biol (2007) 0.78
Is the cellular response to cigarette smoke predictive of the phenotypic variation of COPD? Am J Physiol Lung Cell Mol Physiol (2011) 0.77
Perspectives, translational research, and letters to the editor. Am J Physiol Lung Cell Mol Physiol (2006) 0.75