Published in Evid Based Complement Alternat Med on March 14, 2012
Suppression of lung inflammation in an LPS-induced acute lung injury model by the fruit hull of Gleditsia sinensis. BMC Complement Altern Med (2014) 0.78
Therapeutic Effect of Chung-Pae, an Experimental Herbal Formula, on Acute Lung Inflammation Is Associated with Suppression of NF- κ B and Activation of Nrf2. Evid Based Complement Alternat Med (2013) 0.77
The inhibitory effects of Geranium thunbergii on interferon-γ- and LPS-induced inflammatory responses are mediated by Nrf2 activation. Int J Mol Med (2015) 0.76
JS-III-49, a hydroquinone derivative, exerts anti-inflammatory activity by targeting Akt and p38. Korean J Physiol Pharmacol (2017) 0.75
The Fruit Hull of Gleditsia sinensis Enhances the Anti-Tumor Effect of cis-Diammine Dichloridoplatinum II (Cisplatin). Evid Based Complement Alternat Med (2016) 0.75
Glycosylation enables aesculin to activate Nrf2. Sci Rep (2016) 0.75
Geraniin attenuates LPS-induced acute lung injury via inhibiting NF-κB and activating Nrf2 signaling pathways. Oncotarget (2017) 0.75
Therapeutic Potential of Medicinal Plants and Their Constituents on Lung Inflammatory Disorders. Biomol Ther (Seoul) (2016) 0.75
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun (1997) 14.09
Oxidative stress, inflammation, and cancer: how are they linked? Free Radic Biol Med (2010) 7.31
Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase. J Biol Chem (1994) 6.91
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J Clin Invest (2004) 6.32
Innate immune sensing and its roots: the story of endotoxin. Nat Rev Immunol (2003) 5.46
Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis. J Clin Invest (2006) 4.41
Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice. J Exp Med (2005) 4.31
Nrf2:INrf2 (Keap1) signaling in oxidative stress. Free Radic Biol Med (2009) 4.26
Nrf2 is essential for protection against acute pulmonary injury in mice. Proc Natl Acad Sci U S A (1999) 3.79
New insights into the role of nuclear factor-kappaB, a ubiquitous transcription factor in the initiation of diseases. Clin Chem (1999) 2.97
Nrf2 defends the lung from oxidative stress. Antioxid Redox Signal (2006) 2.96
Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: the effect of antiinflammatory agents. J Exp Med (1991) 2.59
The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration. Ann N Y Acad Sci (2008) 2.35
Elevated levels of NAP-1/interleukin-8 are present in the airspaces of patients with the adult respiratory distress syndrome and are associated with increased mortality. Am Rev Respir Dis (1992) 2.11
Role of 15-deoxy delta(12,14) prostaglandin J2 and Nrf2 pathways in protection against acute lung injury. Am J Respir Crit Care Med (2005) 1.94
Fibroproliferative phase of ARDS. Clinical findings and effects of corticosteroids. Chest (1991) 1.91
Evaluation of definitions for adult respiratory distress syndrome. Am J Respir Crit Care Med (1994) 1.60
Nuclear factor-kappa B is activated in alveolar macrophages from patients with acute respiratory distress syndrome. Crit Care Med (1996) 1.55
The role of nuclear factor kappa B in the pathogenesis of pulmonary diseases: implications for therapy. Am J Respir Med (2003) 1.27
Acute lung injury and the acute respiratory distress syndrome: pathophysiology and treatment. Mo Med (2010) 1.17
Lung protective ventilation strategy for the acute respiratory distress syndrome. Cochrane Database Syst Rev (2007) 1.14
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS): the mechanism, present strategies and future perspectives of therapies. J Zhejiang Univ Sci B (2007) 1.02
Induction and function of lipocalin prostaglandin D synthase in host immunity. J Immunol (2007) 1.01
The role of nuclear factor-kappaB in inflammatory lung disease. Inflamm Allergy Drug Targets (2010) 0.95
Efficacy of inhaled nitric oxide in patients with severe ARDS. Chest (1995) 0.94
ent-kaur-16-en-19-oic Acid, isolated from the roots of Aralia continentalis, induces activation of Nrf2. J Ethnopharmacol (2011) 0.83
Inhibition of experimental allergic rhinitis by the n-butanol fraction from the anomalous fruits of Gleditsia sinensis. Biol Pharm Bull (2003) 0.82
Triterpenoidal saponins from Gleditsia sinensis. Phytochemistry (1999) 0.82
Triterpenoidal saponins acylated with two monoterpenic acids from Gleditsia sinensis. Chem Pharm Bull (Tokyo) (1999) 0.81
Gleditsia saponins. Planta Med (1982) 0.80
Do corticosteroids have a role in preventing or reducing acute toxic lung injury caused by inhalation of chemical agents? Clin Toxicol (Phila) (2011) 0.79
Pathogen-host interactions in Pseudomonas aeruginosa pneumonia. Am J Respir Crit Care Med (2005) 3.52
Duration and intensity of NF-kappaB activity determine the severity of endotoxin-induced acute lung injury. J Immunol (2006) 2.96
Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway. J Clin Invest (2007) 2.36
Selective cyclooxygenase-1 and -2 inhibitors each increase allergic inflammation and airway hyperresponsiveness in mice. Am J Respir Crit Care Med (2002) 2.17
Airway epithelium controls lung inflammation and injury through the NF-kappa B pathway. J Immunol (2007) 2.07
Macrophages are necessary for maximal nuclear factor-kappa B activation in response to endotoxin. Am J Respir Cell Mol Biol (2002) 2.05
A woman in her 40s with AIDS and lung mass. Chest (2014) 1.99
Monocytes are potent facilitators of alveolar neutrophil emigration during lung inflammation: role of the CCL2-CCR2 axis. J Immunol (2003) 1.95
Resident alveolar macrophages are replaced by recruited monocytes in response to endotoxin-induced lung inflammation. Am J Respir Cell Mol Biol (2006) 1.70
NADPH oxidase limits innate immune responses in the lungs in mice. PLoS One (2010) 1.69
Targeted immunomodulation of the NF-kappaB pathway in airway epithelium impacts host defense against Pseudomonas aeruginosa. J Immunol (2006) 1.62
Role of resident alveolar macrophages in leukocyte traffic into the alveolar air space of intact mice. Am J Physiol Lung Cell Mol Physiol (2002) 1.51
Macrophage Turnover Kinetics in the Lungs of Mice Infected with Streptococcus pneumoniae. Am J Respir Cell Mol Biol (2007) 1.42
Involvement of cyclooxygenase-2 and prostaglandins in the molecular pathogenesis of inflammatory lung diseases. Am J Physiol Lung Cell Mol Physiol (2006) 1.40
The case. Hypokalemia associated with nephrocalcinosis. Distal renal tubular acidosis associated with Sjögren's syndrome. Kidney Int (2009) 1.39
p47phox deficiency impairs NF-kappa B activation and host defense in Pseudomonas pneumonia. J Immunol (2004) 1.36
Selective I kappa B kinase expression in airway epithelium generates neutrophilic lung inflammation. J Immunol (2003) 1.34
Bacterial clearance of Pseudomonas aeruginosa is enhanced by the inhibition of COX-2. Eur J Immunol (2007) 1.32
Prevalence of type 2 diabetes in patients with obstructive sleep apnea in a multi-ethnic sample. J Clin Sleep Med (2009) 1.29
A central role for tumor-derived monocyte chemoattractant protein-1 in malignant pleural effusion. J Natl Cancer Inst (2008) 1.29
The role of nuclear factor kappa B in the pathogenesis of pulmonary diseases: implications for therapy. Am J Respir Med (2003) 1.27
Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the omega-3 polyunsaturated fatty acid docosahexaenoic acid. J Biol Chem (2008) 1.26
An improved LC-MS/MS method for the quantification of prostaglandins E(2) and D(2) production in biological fluids. Anal Biochem (2007) 1.25
Pneumolysin-induced lung injury is independent of leukocyte trafficking into the alveolar space. J Immunol (2004) 1.23
Importance of CXC chemokine receptor 2 in alveolar neutrophil and exudate macrophage recruitment in response to pneumococcal lung infection. Infect Immun (2010) 1.23
E3 ubiquitin ligase Cblb regulates the acute inflammatory response underlying lung injury. Nat Med (2007) 1.22
Host nuclear factor-kappaB activation potentiates lung cancer metastasis. Mol Cancer Res (2008) 1.22
CCR2-positive monocytes recruited to inflamed lungs downregulate local CCL2 chemokine levels. Am J Physiol Lung Cell Mol Physiol (2004) 1.18
Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase beta. J Virol (2005) 1.16
Effectiveness of pharmacopuncture for asthma: a systematic review and meta-analysis. Evid Based Complement Alternat Med (2010) 1.15
Retracted Substance P and beta-endorphin mediate electro-acupuncture induced analgesia in mouse cancer pain model. J Exp Clin Cancer Res (2009) 1.15
Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation. Am J Respir Crit Care Med (2013) 1.15
FoxM1 mediates the progenitor function of type II epithelial cells in repairing alveolar injury induced by Pseudomonas aeruginosa. J Exp Med (2011) 1.14
Non-tuberculous mycobacterial disease is common in patients with non-cystic fibrosis bronchiectasis. Int J Infect Dis (2013) 1.12
Intratracheal administration of liposomal clodronate accelerates alveolar macrophage reconstitution following fetal liver transplantation. J Leukoc Biol (2004) 1.11
NIK is involved in nucleosomal regulation by enhancing histone H3 phosphorylation by IKKalpha. J Biol Chem (2006) 1.08
TREM-1 expression in macrophages is regulated at transcriptional level by NF-kappaB and PU.1. Eur J Immunol (2007) 1.07
Nuclear factor kappa B is a promising therapeutic target in inflammatory lung disease. Curr Drug Targets (2006) 1.05
Hepatitis C virus core protein leads to immune suppression and liver damage in a transgenic murine model. J Virol (2002) 1.05
Dangkwisoo-san, an herbal medicinal formula, ameliorates acute lung inflammation via activation of Nrf2 and suppression of NF-κB. J Ethnopharmacol (2012) 1.04
Inducible binding of PU.1 and interacting proteins to the Toll-like receptor 4 promoter during endotoxemia. Am J Physiol Lung Cell Mol Physiol (2005) 1.04
Functional PU.1 in macrophages has a pivotal role in NF-κB activation and neutrophilic lung inflammation during endotoxemia. Blood (2011) 1.03
NF-kappaB regulates thrombin-induced ICAM-1 gene expression in cooperation with NFAT by binding to the intronic NF-kappaB site in the ICAM-1 gene. Physiol Genomics (2009) 1.03
Moxibustion for treating pain: a systematic review. Am J Chin Med (2010) 1.01
Transcriptional regulation of the cyclooxygenase-2 gene in macrophages by PU.1. J Biol Chem (2003) 1.01
Induction and function of lipocalin prostaglandin D synthase in host immunity. J Immunol (2007) 1.01
Myeloid cells control termination of lung inflammation through the NF-kappaB pathway. Am J Physiol Lung Cell Mol Physiol (2008) 1.01
Protective role of reactive oxygen species in endotoxin-induced lung inflammation through modulation of IL-10 expression. J Immunol (2012) 1.00
Ran suppresses paclitaxel-induced apoptosis in human glioblastoma cells. Apoptosis (2008) 0.99
Bioluminescent detection of endotoxin effects on HIV-1 LTR-driven transcription in vivo. J Histochem Cytochem (2003) 0.99
Efficacy of a traditional Korean medicine, Chung-Sang-Bo-Ha-Tang, in a murine model of chronic asthma. Int Immunopharmacol (2005) 0.98
Idiopathic pulmonary artery dissection: a case report. J Med Case Rep (2009) 0.98
Local delivery of GM-CSF protects mice from lethal pneumococcal pneumonia. J Immunol (2011) 0.98
MYD88-dependent and -independent activation of TREM-1 via specific TLR ligands. Eur J Immunol (2010) 0.98
Tumor necrosis factor-alpha-mediated suppression of adipocyte apolipoprotein E gene transcription: primary role for the nuclear factor (NF)-kappaB pathway and NFkappaB p50. Endocrinology (2008) 0.96
Regulation of macrophage cyclooxygenase-2 gene expression by modifications of histone H3. Am J Physiol Lung Cell Mol Physiol (2003) 0.95
PGD synthase and PGD2 in immune resposne. Mediators Inflamm (2012) 0.95
Systemic nf-kappaB activation in a transgenic mouse model of acute pancreatitis. J Surg Res (2003) 0.95
The novel role of IL-7 ligation to IL-7 receptor in myeloid cells of rheumatoid arthritis and collagen-induced arthritis. J Immunol (2013) 0.95
Endotoxin potentiates lung injury in cerulein-induced pancreatitis. Am J Surg (2003) 0.95
Modulation of endotoxin-induced NF-kappa B activation in lung and liver through TNF type 1 and IL-1 receptors. Am J Physiol Lung Cell Mol Physiol (2002) 0.93
A novel peptide nanomedicine against acute lung injury: GLP-1 in phospholipid micelles. Pharm Res (2010) 0.92
Ethanol extract of Alismatis Rhizoma reduces acute lung inflammation by suppressing NF-κB and activating Nrf2. J Ethnopharmacol (2013) 0.92
Competitive enzymatic interactions determine the relative amounts of prostaglandins E2 and D2. J Pharmacol Exp Ther (2011) 0.92
Rehmannia glutinosa suppresses inflammatory responses elicited by advanced glycation end products. Inflammation (2012) 0.91
Map kinase phosphatase 5 protects against sepsis-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol (2012) 0.90
Dendritic cell depletion and repopulation in the lung after irradiation and bone marrow transplantation in mice. Am J Respir Cell Mol Biol (2010) 0.89
Recruited alveolar macrophages, in response to airway epithelial-derived monocyte chemoattractant protein 1/CCl2, regulate airway inflammation and remodeling in allergic asthma. Am J Respir Cell Mol Biol (2015) 0.89
Yin Yang 1 enhances cyclooxygenase-2 gene expression in macrophages. Am J Physiol Lung Cell Mol Physiol (2007) 0.88
Lipopolysaccharide-dependent interaction between PU.1 and c-Jun determines production of lipocalin-type prostaglandin D synthase and prostaglandin D2 in macrophages. Am J Physiol Lung Cell Mol Physiol (2009) 0.88
Lung cancer mimicking as pregnancy with pneumonia. Lung Cancer (2008) 0.88
Inhibition effects of Moutan Cortex Radicis on secretion of eotaxin in A549 human epithelial cells and eosinophil migration. J Ethnopharmacol (2007) 0.88
Hepatic cryoablation-induced multisystem injury: bioluminescent detection of NF-kappaB activation in a transgenic mouse model. J Gastrointest Surg (2002) 0.88
Role of nicotinamide adenine dinucleotide phosphate-reduced oxidase proteins in Pseudomonas aeruginosa-induced lung inflammation and permeability. Am J Respir Cell Mol Biol (2013) 0.87
Peptidylarginine deiminase 2 suppresses inhibitory {kappa}B kinase activity in lipopolysaccharide-stimulated RAW 264.7 macrophages. J Biol Chem (2010) 0.87