Published in Methods Enzymol on January 01, 2003
Synthesis of Tetrazolo-Fused Benzodiazepines and Benzodiazepinones by a Two-Step Protocol Using an Ugi-Azide Reaction for Initial Diversity Generation. Tetrahedron (2012) 0.97
A novel route to synthesize libraries of quinoxalines via Petasis methodology in two synthetic operations. Tetrahedron Lett (2011) 0.86
One-pot synthesis of tetracyclic fused imidazo[1,2-a]pyridines via a three-component reaction. Beilstein J Org Chem (2016) 0.75
The biology of avian Eimeria with an emphasis on their control by vaccination. Adv Parasitol (2005) 1.90
Early events in the thymus affect the balance of effector and regulatory T cells. Nature (2006) 1.78
Visualizing the neutrophil response to sterile tissue injury in mouse dermis reveals a three-phase cascade of events. J Invest Dermatol (2011) 1.51
Two CD1 genes map to the chicken MHC, indicating that CD1 genes are ancient and likely to have been present in the primordial MHC. Proc Natl Acad Sci U S A (2005) 1.25
Expression patterns of chicken Toll-like receptor mRNA in tissues, immune cell subsets and cell lines. Vet Immunol Immunopathol (2005) 1.24
Identification and functional characterization of chicken toll-like receptor 5 reveals a fundamental role in the biology of infection with Salmonella enterica serovar typhimurium. Infect Immun (2005) 1.24
Allelic variation in TLR4 is linked to susceptibility to Salmonella enterica serovar Typhimurium infection in chickens. Infect Immun (2003) 1.22
Identification and characterization of a functional, alternatively spliced Toll-like receptor 7 (TLR7) and genomic disruption of TLR8 in chickens. Immunology (2005) 1.13
Challenges in the successful control of the avian coccidia. Vaccine (2006) 1.11
Rapid assembly of molecular diversity via exploitation of isocyanide-based multi-component reactions. Curr Opin Drug Discov Devel (2003) 1.10
Cloning and characterization of chicken IL-10 and its role in the immune response to Eimeria maxima. J Immunol (2004) 1.08
Selective and potent Raf inhibitors paradoxically stimulate normal cell proliferation and tumor growth. Mol Cancer Ther (2010) 1.04
A critical role for MAPK signalling pathways in the transcriptional regulation of toll like receptors. PLoS One (2013) 1.02
Intestinal intraepithelial lymphocytes sustain the epithelial barrier function against Eimeria vermiformis infection. Infect Immun (2006) 1.01
Ectopic restriction of DNA repair reveals that UNG2 excises AID-induced uracils predominantly or exclusively during G1 phase. J Exp Med (2012) 1.00
Fragment based drug discovery: practical implementation based on ¹⁹F NMR spectroscopy. J Med Chem (2012) 0.99
A novel series of potent gamma-secretase inhibitors based on a benzobicyclo[4.2.1]nonane core. Bioorg Med Chem Lett (2005) 0.98
From fragment screening to in vivo efficacy: optimization of a series of 2-aminoquinolines as potent inhibitors of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1). J Med Chem (2011) 0.98
Evolution of a highly selective and potent 2-(pyridin-2-yl)-1,3,5-triazine Tie-2 kinase inhibitor. J Med Chem (2007) 0.96
Design of novel histone deacetylase inhibitors. Bioorg Med Chem Lett (2007) 0.95
A genetic and functional relationship between T cells and cellular proliferation in the adult hippocampus. PLoS Biol (2010) 0.95
Visualizing dendritic cell migration within the skin. Histochem Cell Biol (2008) 0.95
Genetic mapping identifies novel highly protective antigens for an apicomplexan parasite. PLoS Pathog (2011) 0.94
Clearance of enteric Salmonella enterica serovar Typhimurium in chickens is independent of B-cell function. Infect Immun (2006) 0.94
Eimeria maxima: the influence of host genotype on parasite reproduction as revealed by quantitative real-time PCR. Int J Parasitol (2005) 0.94
TLR15 is unique to avian and reptilian lineages and recognizes a yeast-derived agonist. J Immunol (2012) 0.93
Rapid identification of a novel small molecule phosphodiesterase 10A (PDE10A) tracer. J Med Chem (2012) 0.92
The Cinderella syndrome: why do malaria-infected cells burst at midnight? Trends Parasitol (2012) 0.89
Peyer's patches are required for the induction of rapid Th1 responses in the gut and mesenteric lymph nodes during an enteric infection. J Immunol (2006) 0.88
Total synthesis of (+)-crocacin C using hidden symmetry. J Org Chem (2010) 0.87
Selective inhibitors of the mutant B-Raf pathway: discovery of a potent and orally bioavailable aminoisoquinoline. J Med Chem (2009) 0.87
Ammonium chloride-promoted four-component synthesis of pyrrolo[3,4-b]pyridin-5-one. J Am Chem Soc (2002) 0.85
The duck toll like receptor 7: genomic organization, expression and function. Mol Immunol (2007) 0.85
EmaxDB: Availability of a first draft genome sequence for the apicomplexan Eimeria maxima. Mol Biochem Parasitol (2012) 0.84
Development and validation of real-time polymerase chain reaction assays specific to four species of Eimeria. Avian Pathol (2008) 0.84
A strong antigen-specific T-cell response is associated with age and genetically dependent resistance to avian enteric salmonellosis. Infect Immun (2005) 0.84
Murine goblet cell hypoplasia during Eimeria pragensis infection is ameliorated by clindamycin treatment. J Vet Med Sci (2005) 0.83
Novel vanilloid receptor-1 antagonists: 2. Structure-activity relationships of 4-oxopyrimidines leading to the selection of a clinical candidate. J Med Chem (2007) 0.83
Reverse cope elimination of hydroxylamines and alkenes or alkynes: theoretical investigation of tether length and substituent effects. J Am Chem Soc (2012) 0.83
Selective class I phosphoinositide 3-kinase inhibitors: optimization of a series of pyridyltriazines leading to the identification of a clinical candidate, AMG 511. J Med Chem (2012) 0.83
Factors influencing the abundance of the side population in a human myeloma cell line. Bone Marrow Res (2011) 0.83
Harnessing single cell sorting to identify cell division genes and regulators in bacteria. PLoS One (2013) 0.82
T cell activation: in vivo veritas. Immunol Cell Biol (2004) 0.82
Parasite genetics and the immune host: recombination between antigenic types of Eimeria maxima as an entrée to the identification of protective antigens. Mol Biochem Parasitol (2004) 0.82
Clonal structure of rapid-onset MDV-driven CD4+ lymphomas and responding CD8+ T cells. PLoS Pathog (2011) 0.81
Regional and global changes in TCRalphabeta T cell repertoires in the gut are dependent upon the complexity of the enteric microflora. Dev Comp Immunol (2009) 0.81
Innate responsiveness of CD8 memory T-cell populations nonspecifically inhibits allergic sensitization. J Allergy Clin Immunol (2008) 0.81
Parallel medicinal chemistry approaches to selective HDAC1/HDAC2 inhibitor (SHI-1:2) optimization. Bioorg Med Chem Lett (2008) 0.80
γδ T cells play a protective role during infection with Nippostrongylus brasiliensis by promoting goblet cell function in the small intestine. Immunology (2011) 0.80
One-pot microwave assisted preparation of pyrazoloquinazolinone libraries. Mol Divers (2003) 0.79
A one-pot four-component (ABC2) synthesis of macrocycles. Angew Chem Int Ed Engl (2003) 0.78
The influence of immunizing dose size and schedule on immunity to subsequent challenge with antigenically distinct strains of Eimeria maxima. Avian Pathol (2005) 0.77
A genetic linkage map for the apicomplexan protozoan parasite Eimeria maxima and comparison with Eimeria tenella. Int J Parasitol (2010) 0.77
A five-component synthesis of hexasubstituted benzene. Angew Chem Int Ed Engl (2002) 0.76
Novel vanilloid receptor-1 antagonists: 1. Conformationally restricted analogues of trans-cinnamides. J Med Chem (2007) 0.76
Discovery of protein-protein binding disruptors using multi-component condensations small molecules. Bioorg Med Chem Lett (2006) 0.76
Antibody response to Salmonella: its induction and role in protection against avian enteric salmonellosis. Expert Rev Anti Infect Ther (2007) 0.75
The relationship between the anticoccidial effects of clindamycin and the development of immunity in the Eimeria pragensis/mouse model of large intestinal coccidiosis. J Vet Med Sci (2005) 0.75
Solid-phase synthesis and structure-activity relationships of novel biarylethers as melanin-concentrating hormone receptor-1 antagonists. Bioorg Med Chem Lett (2006) 0.75
Induction of lymphomas by inoculation of Marek's disease virus-derived lymphoblastoid cell lines: prevention by CVI988 vaccination. Avian Pathol (2012) 0.75
A convergent approach to (-)-callystatin A based on local symmetry. Chemistry (2012) 0.75
5-Aminooxazole as an internal traceless activator of C-terminal carboxylic acid: rapid access to diversely functionalized cyclodepsipeptides. Chemistry (2006) 0.75
Enantioselective enzymatic desymmetrization of highly functionalized meso tetrahydropyranyl diols. Org Lett (2009) 0.75
Halothane-anesthetized rabbit: a new experimental model to test the effects of besipirdine and duloxetine on lower urinary tract function. Urol Int (2010) 0.75
Lead optimization of 4,4-biaryl piperidine amides as γ-secretase inhibitors. Bioorg Med Chem Lett (2012) 0.75
Discovery of 2-methylpyridine-based biaryl amides as γ-secretase modulators for the treatment of Alzheimer's disease. Bioorg Med Chem Lett (2013) 0.75