Anticancer drug response and expression of molecular markers in early-passage xenotransplanted colon carcinomas.

PubWeight™: 1.61‹?› | Rank: Top 4%

🔗 View Article (PMID 14728946)

Published in Eur J Cancer on January 01, 2004

Authors

I Fichtner1, W Slisow, J Gill, M Becker, B Elbe, T Hillebrand, M Bibby

Author Affiliations

1: Max-Delbrück-Center for Molecular Medicine, Experimantal Pharmacology, Robert-Roessle-Str. 10, D-13092 Berlin-Buch, Germany. fichtner@mdc-berlin.de

Articles citing this

Discovery and preclinical validation of drug indications using compendia of public gene expression data. Sci Transl Med (2011) 5.77

Patient-derived tumour xenografts as models for oncology drug development. Nat Rev Clin Oncol (2012) 4.00

Patient-derived tumor xenografts: transforming clinical samples into mouse models. Cancer Res (2013) 2.74

The promise of patient-derived xenografts: the best laid plans of mice and men. Clin Cancer Res (2012) 1.63

One mouse, one patient paradigm: New avatars of personalized cancer therapy. Cancer Lett (2013) 1.49

Apoptosis and molecular targeting therapy in cancer. Biomed Res Int (2014) 1.47

Pre-clinical mouse models of human prostate cancer and their utility in drug discovery. Curr Protoc Pharmacol (2010) 1.12

Using heterogeneity of the patient-derived xenograft model to identify the chemoresistant population in ovarian cancer. Oncotarget (2014) 1.06

Regorafenib (BAY 73-4506): antitumor and antimetastatic activities in preclinical models of colorectal cancer. Int J Cancer (2014) 1.05

Histological and molecular evaluation of patient-derived colorectal cancer explants. PLoS One (2012) 1.01

Development and characterization of xenograft model systems for adenoid cystic carcinoma. Lab Invest (2011) 1.01

Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models. Invest New Drugs (2010) 1.01

Effect of Pathologic Tumor Response and Nodal Status on Survival in the Medical Research Council Adjuvant Gastric Infusional Chemotherapy Trial. J Clin Oncol (2016) 1.00

Pharmacological inhibition of p38 MAPK reduces tumor growth in patient-derived xenografts from colon tumors. Oncotarget (2015) 0.90

Establishment and characterization of esophageal squamous cell carcinoma patient-derived xenograft mouse models for preclinical drug discovery. Lab Invest (2014) 0.87

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors. Nat Commun (2017) 0.87

Establishment and characterization of patient-derived tumor xenograft using gastroscopic biopsies in gastric cancer. Sci Rep (2015) 0.87

Establishment and characterisation of patient-derived xenografts as paraclinical models for gastric cancer. Sci Rep (2016) 0.83

Bi-PROF: bisulfite profiling of target regions using 454 GS FLX Titanium technology. Epigenetics (2013) 0.82

Chemoresistance acquisition induces a global shift of expression of aniogenesis-associated genes and increased pro-angogenic activity in neuroblastoma cells. Mol Cancer (2009) 0.82

Phenotypic and transcriptional fidelity of patient-derived colon cancer xenografts in immune-deficient mice. PLoS One (2013) 0.81

Cellular pharmacology of multi- and duplex drugs consisting of ethynylcytidine and 5-fluoro-2'-deoxyuridine. Invest New Drugs (2009) 0.80

Identification of DEK as a potential therapeutic target for neuroendocrine prostate cancer. Oncotarget (2015) 0.80

Appropriateness of using patient-derived xenograft models for pharmacologic evaluation of novel therapies for esophageal/gastro-esophageal junction cancers. PLoS One (2015) 0.79

Patient-derived xenograft models of colorectal cancer in pre-clinical research: a systematic review. Oncotarget (2016) 0.77

Activation of the mTOR Pathway by Oxaliplatin in the Treatment of Colorectal Cancer Liver Metastasis. PLoS One (2017) 0.75

Pathologic tumor response to neoadjuvant chemotherapy in gastroesophageal cancer: what does it mean? Transl Gastroenterol Hepatol (2016) 0.75

Optimized creation of glioblastoma patient derived xenografts for use in preclinical studies. J Transl Med (2017) 0.75

Novel translational strategies in colorectal cancer research. World J Gastroenterol (2007) 0.75

Mechanisms of drug resistance in colon cancer and its therapeutic strategies. World J Gastroenterol (2016) 0.75

Modeling of Patient Derived Xenografts in Colorectal Cancer. Mol Cancer Ther (2017) 0.75

Insights from animal models of bladder cancer: recent advances, challenges, and opportunities. Oncotarget (2017) 0.75

Articles by these authors

Complete genome sequence of Neisseria meningitidis serogroup B strain MC58. Science (2000) 16.04

Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains. J Bacteriol (2002) 8.88

Generation and analysis of 280,000 human expressed sequence tags. Genome Res (1996) 8.27

Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis. Nat Genet (2000) 4.83

Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara. Nat Med (1998) 4.13

A signal peptide cleavage site mutation in the cationic trypsinogen gene is strongly associated with chronic pancreatitis. Gastroenterology (1999) 4.10

Picosecond kinetics of the initial photochemical electron-transfer reaction in bacterial photosynthetic reaction centers. Biochemistry (1985) 3.30

Prognostic importance of initial response in HIV-1 infected patients starting potent antiretroviral therapy: analysis of prospective studies. Lancet (2003) 3.23

Large-scale reductions in speeding and accidents in Canada and Israel: a behavioral ecological perspective. J Appl Behav Anal (1985) 2.93

Systematic review: kidney transplantation compared with dialysis in clinically relevant outcomes. Am J Transplant (2011) 2.69

Combination therapy with efavirenz, nelfinavir, and nucleoside reverse-transcriptase inhibitors in children infected with human immunodeficiency virus type 1. Pediatric AIDS Clinical Trials Group 382 Team. N Engl J Med (1999) 2.67

Evaluation of the Directigen FluA+B test for rapid diagnosis of influenza virus type A and B infections. J Clin Microbiol (2002) 2.56

Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Nature (2000) 2.16

Novel four-drug salvage treatment regimens after failure of a human immunodeficiency virus type 1 protease inhibitor-containing regimen: antiviral activity and correlation of baseline phenotypic drug susceptibility with virologic outcome. J Infect Dis (1999) 2.12

Primordial role of CD34+ 38- cells in early and late trilineage haemopoietic engraftment after autologous blood cell transplantation. Br J Haematol (1998) 2.10

Low infection rate and long durability of nontunneled silastic catheters. A safe and cost-effective alternative for long-term venous access. Arch Intern Med (1993) 2.10

Three genes coding for subunits of the membrane sector (F0) of the Escherichia coli adenosine triphosphatase complex. J Bacteriol (1981) 1.97

Mutation in the SPINK1 trypsin inhibitor gene, alcohol use, and chronic pancreatitis. JAMA (2001) 1.81

Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha. J Biol Chem (1995) 1.81

Nature, time course and dose dependence of zidovudine-related side effects: results from the Multicenter Canadian Azidothymidine Trial. AIDS (1989) 1.78

Enhancement of MHC class I-restricted peptide-specific T cell induction by a DNA prime/MVA boost vaccination regime. Vaccine (1998) 1.74

A general method for the specific isolation of peptides containing modified residues, using insoluble antibody columns. Biochemistry (1971) 1.70

The changing pattern of mortality and morbidity from radical cystectomy. BJU Int (2000) 1.68

Loss of CD4+ T cell proliferative ability but not loss of human immunodeficiency virus type 1 specificity equates with progression to disease. J Infect Dis (2000) 1.66

Evidence-based, interdisciplinary guidelines for anti-inflammatory treatment of uveitis associated with juvenile idiopathic arthritis. Rheumatol Int (2011) 1.64

Computed tomographic evaluation of head diseases in the horse: 15 cases. Equine Vet J (1996) 1.62

A 500-kiloton airburst over Chelyabinsk and an enhanced hazard from small impactors. Nature (2013) 1.61

Cardiac risk factors and the use of cardioprotective medications in patients with chronic renal insufficiency. Am J Kidney Dis (2001) 1.57

Iatrogenic atrioventricular bypass tract following a Fontan operation for tricuspid atresia. Heart (1997) 1.55

Rapid signalling by androgen receptor in prostate cancer cells. Oncogene (1999) 1.54

The role of the high dependency unit in postoperative care: an update. Ann R Coll Surg Engl (1990) 1.54

Mutations of the DPC4/Smad4 gene in biliary tract carcinoma. Cancer Res (1998) 1.52

Alterations in atrial electrophysiology associated with chronic atrial fibrillation in man. Eur Heart J (1999) 1.50

A clinical study of parenchymal and subdural miniature strain-gauge transducers for monitoring intracranial pressure. Neurosurgery (1996) 1.48

Isolation and mapping of a polymorphic DNA sequence (pEFD145) on chromosome 3 [D3S32]. Nucleic Acids Res (1988) 1.47

Yttrium-90-labeled anti-CD20 monoclonal antibody therapy of recurrent B-cell lymphoma. Clin Cancer Res (1996) 1.47

Rare benign neoplasms of the larynx: rhabdomyoma and lipoma. ORL J Otorhinolaryngol Relat Spec (1996) 1.47

Increased prevalence of the Taq I A1 allele of the dopamine receptor gene (DRD2) in obesity with comorbid substance use disorder: a preliminary report. Pharmacogenetics (1996) 1.43

The impact of pancreas transplantation on kidney allograft survival. Am J Transplant (2011) 1.42

Therapeutically interchangeable? A study of real-world outcomes associated with switching basal insulin analogues among US patients with type 2 diabetes mellitus using electronic medical records data. Diabetes Obes Metab (2014) 1.42

Analysis of the p53/BAX pathway in colorectal cancer: low BAX is a negative prognostic factor in patients with resected liver metastases. J Clin Oncol (1999) 1.40

[Comment on the contribution by J. Zieren, H. U. Jacobi, J. M. Müller, "The plug-and-patch repair in managing inguinal hernia in the adult"]. Zentralbl Chir (1997) 1.40

Are there antiendometrial antibodies in sera of women with endometriosis? Fertil Steril (1991) 1.39

Preventive medicine: what do future practitioners really need? Are they getting it in medical school? J Ky Med Assoc (1993) 1.39

Kaposi's sarcoma after repeated surgical procedures in an immunocompetent patient: the lymphatic hypothesis. Dermatology (2010) 1.39

Both AP-1 and Cbfa1-like factors are required for the induction of interstitial collagenase by parathyroid hormone. Oncogene (1999) 1.38

A multicenter study of viral hepatitis in a United States hemophilic population. Blood (1993) 1.37

Monoclonal antibodies against cell-surface antigens of developing cells of Myxococcus xanthus. Ann Inst Pasteur Microbiol (1985) 1.37

Solid-organ transplantation in older adults: current status and future research. Am J Transplant (2012) 1.33

Risk indicators for malnutrition are associated inversely with quality of life for participants in meal programs for older adults. J Am Diet Assoc (1998) 1.32

Immunogenicities of intravenous and intramuscular administrations of modified vaccinia virus Ankara-based multi-CTL epitope vaccine for human immunodeficiency virus type 1 in mice. J Gen Virol (1998) 1.32

The fasciocutaneous supraclavicular artery island flap for releasing postburn mentosternal contractures. Plast Reconstr Surg (1997) 1.31

Histopathology of submandibular glands removed for sialolithiasis. Ann Otol Rhinol Laryngol (2001) 1.29

Management of renal collecting duct carcinoma: a systematic review and the McMaster experience. Curr Oncol (2013) 1.23

Human Kaposi's sarcoma cell-mediated tumorigenesis in human immunodeficiency type 1 tat-expressing transgenic mice. J Natl Cancer Inst (2000) 1.23

New approaches in imaging of the brachial plexus. Eur J Radiol (2010) 1.23

Randomized trial of a home-based family intervention for children who have deliberately poisoned themselves. J Am Acad Child Adolesc Psychiatry (1998) 1.22

Native DNA binding in rheumatoid arthritis. Ann Rheum Dis (1974) 1.20

Income of living kidney donors and the income difference between living kidney donors and their recipients in the United States. Am J Transplant (2012) 1.20

Delusions and behavioral disturbances in cognitively impaired elderly persons. J Am Geriatr Soc (1992) 1.19

Isolation and mapping of a polymorphic DNA sequence pMLJ14 on chromosome 14 [D14S13]. Nucleic Acids Res (1988) 1.18

Anti-myeloperoxidase autoantibodies react with native but not denatured myeloperoxidase. Clin Exp Immunol (1992) 1.17

An index of risk for obstructive airways disease. Am Rev Respir Dis (1982) 1.17

The delivery of antisense therapeutics. Adv Drug Deliv Rev (2000) 1.15

Judgments of quality of life of individuals with severe mental disorders: Patient self-report versus provider perspectives. Am J Psychiatry (1996) 1.15

Cost-effectiveness analysis of a home-based social work intervention for children and adolescents who have deliberately poisoned themselves. Results of a randomised controlled trial. Br J Psychiatry (1999) 1.14

The copper chaperone CCS is abundant in neurons and astrocytes in human and rodent brain. J Neurochem (1999) 1.13

Suppression of Helicobacter pylori reduces gastrin releasing peptide stimulated gastrin release in duodenal ulcer patients. Gut (1992) 1.13

Protection from Plasmodium berghei infection by priming and boosting T cells to a single class I-restricted epitope with recombinant carriers suitable for human use. Eur J Immunol (1998) 1.13

Choledocholithiasis and bile duct stenosis: diagnostic accuracy of MR cholangiopancreatography. Radiology (1997) 1.12

Highly active anti-retroviral therapy (HAART) prolongs time to treatment failure in Kaposi's sarcoma. AIDS (1999) 1.12

Schwannoma of the brachial plexus. Ann Otol Rhinol Laryngol (1996) 1.12

Polycystic horseshoe kidney. J Urol (1997) 1.12

Static fundus perimetry using the scanning laser ophthalmoscope with an automated threshold strategy. Graefes Arch Clin Exp Ophthalmol (1995) 1.11

The value of permanent follow-up of implantable pacemakers--first results of an European trial. Biomed Tech (Berl) (2002) 1.10

Rheumatoid arthritis and its variants: analysis of scintiphotographic, radiographic, and clinical examinations. AJR Am J Roentgenol (1978) 1.09

Quantification of human cells in NOD/SCID mice by duplex real-time polymerase-chain reaction. Haematologica (2001) 1.08

Staging of laryngeal cancer: endoscopy, computed tomography and magnetic resonance versus histopathology. Eur Arch Otorhinolaryngol (1997) 1.08

Stability of fixation: results of fundus-controlled examination using the scanning laser ophthalmoscope. Ger J Ophthalmol (1995) 1.07

Specificity of parotid sialendoscopy. Laryngoscope (2001) 1.07

Denaturant-induced movement of the transition state of protein folding revealed by high-pressure stopped-flow measurements. Proc Natl Acad Sci U S A (2000) 1.07

Identification of human herpesvirus 8-specific cytotoxic T-cell responses. J Virol (1999) 1.07

[Capillaroscopy. Procedure and nomenclature]. Z Rheumatol (2010) 1.06

Temperature behaviour of human serum albumin. Eur J Biochem (1980) 1.06

Normal values for fundus perimetry with the scanning laser ophthalmoscope. Am J Ophthalmol (1998) 1.05

Endoscopic ultrasound cannot determine suitability for esophagectomy after aggressive chemoradiotherapy for esophageal cancer. Am J Gastroenterol (1999) 1.04

Surgical treatment of Zenker's diverticulum: transcutaneous diverticulectomy versus microendoscopic myotomy of the cricopharyngeal muscle with CO2 laser. Otolaryngol Head Neck Surg (1999) 1.04

Study of DNA-spermine interactions by use of small-angle and wide-angle X-ray scattering and circular dichroism. Nucleic Acids Res (1978) 1.04

Interventional sialendoscopy. Laryngoscope (2000) 1.04

Pretherapeutic staging of laryngeal carcinoma. Clinical findings, computed tomography, and magnetic resonance imaging compared with histopathology. Cancer (1996) 1.04

Aerobic photolysis of alkylcobalamins: quantum yields and light-action spectra. Arch Biochem Biophys (1973) 1.04

Molecular epidemiology and restriction site mapping of adenovirus 7 genome types. Arch Virol (1989) 1.03

[Prognostic factors in surgery of macular holes]. Ophthalmologe (1998) 1.02

Prevalence of Helicobacter pylori infection in Nicaraguan children with persistent diarrhea, diagnosed by the 13C-urea breath test. J Pediatr Gastroenterol Nutr (1997) 1.02

Treatment of hormone-refractory prostate cancer with 90Y-CYT-356 monoclonal antibody. Clin Cancer Res (1996) 1.02

Slime mould actin: homology to vertebrate actin and presence in the nucleus. Exp Cell Res (1974) 1.02

Evaluation of a real-time hybrid three-dimensional echo and X-ray imaging system for guidance of cardiac catheterisation procedures. Med Image Comput Comput Assist Interv (2012) 1.01

HIV and hepatitis C virus coinfection in Canada: challenges and opportunities for reducing preventable morbidity and mortality. HIV Med (2012) 1.01

Nurse's aides in nursing homes: the relationship between organization and quality. Gerontologist (1992) 1.01