Published in Clin Cancer Res on January 01, 2004
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A (2005) 167.46
Rapamycin inhibits F-actin reorganization and phosphorylation of focal adhesion proteins. Oncogene (2008) 1.64
Role of mTOR signaling in tumor cell motility, invasion and metastasis. Curr Protein Pept Sci (2011) 1.37
Systemic disease-induced salivary biomarker profiles in mouse models of melanoma and non-small cell lung cancer. PLoS One (2009) 1.35
Review series: TOR kinase complexes and cell migration. J Cell Biol (2011) 1.19
mTOR signaling in cancer cell motility and tumor metastasis. Crit Rev Eukaryot Gene Expr (2010) 1.13
Rapamycin inhibits multiple stages of c-Neu/ErbB2 induced tumor progression in a transgenic mouse model of HER2-positive breast cancer. Mol Cancer Ther (2007) 1.05
Treating rheumatic patients with a malignancy. Arthritis Res Ther (2011) 1.03
Management and prevention of post-transplant malignancies in kidney transplant recipients. Clin Kidney J (2015) 0.97
Skeletal metastasis: treatments, mouse models, and the Wnt signaling. Chin J Cancer (2013) 0.95
Sirolimus inhibits the growth and metastatic progression of hepatocellular carcinoma. J Cancer Res Clin Oncol (2008) 0.95
Novel synergistic antitumor effects of rapamycin with bortezomib on hepatocellular carcinoma cells and orthotopic tumor model. BMC Cancer (2012) 0.94
1,1-Bis (3'-indolyl)-1-(p-substitutedphenyl)methane compounds inhibit lung cancer cell and tumor growth in a metastasis model. Eur J Pharm Sci (2013) 0.84
Post-transplantation malignancy: a cell autonomous mechanism with implications for therapy. Trans Am Clin Climatol Assoc (2009) 0.83
The Biological Role of PI3K Pathway in Lung Cancer. Pharmaceuticals (Basel) (2012) 0.81
A Rationale for Age-Adapted Immunosuppression in Organ Transplantation. Transplantation (2015) 0.81
Cardamonin Inhibits Metastasis of Lewis Lung Carcinoma Cells by Decreasing mTOR Activity. PLoS One (2015) 0.80
Liver transplantation for hepatocellular carcinoma on cirrhosis: strategies to avoid tumor recurrence. World J Gastroenterol (2011) 0.79
Non-small cell lung carcinoma therapy using mTOR-siRNA. Int J Clin Exp Pathol (2012) 0.79
Expression of set is downregulated by rapamycin in human colorectal cancer cells. Biomed Rep (2013) 0.76
Rapamycin Protects from Type-I Peritoneal Membrane Failure Inhibiting the Angiogenesis, Lymphangiogenesis, and Endo-MT. Biomed Res Int (2015) 0.75
Improved anticancer drug response prediction in cell lines using matrix factorization with similarity regularization. BMC Cancer (2017) 0.75
HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med (2008) 7.42
Urinary-cell mRNA profile and acute cellular rejection in kidney allografts. N Engl J Med (2013) 7.40
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science (2013) 5.10
Messenger RNA for FOXP3 in the urine of renal-allograft recipients. N Engl J Med (2005) 5.02
MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA. Mol Cell Biol (2008) 4.45
New world bats harbor diverse influenza A viruses. PLoS Pathog (2013) 4.10
Distinct endocytic pathways control the rate and extent of synaptic vesicle protein recycling. Neuron (2006) 3.85
Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. Science (2013) 3.72
Retracted MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer. J Biol Chem (2008) 3.63
Identification of a B cell signature associated with renal transplant tolerance in humans. J Clin Invest (2010) 3.59
Polyomavirus-associated nephropathy in renal transplantation: interdisciplinary analyses and recommendations. Transplantation (2005) 3.57
The Akt/PKB pathway: molecular target for cancer drug discovery. Oncogene (2005) 3.42
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis. Nat Chem Biol (2012) 3.40
Quantum-sized carbon dots for bright and colorful photoluminescence. J Am Chem Soc (2006) 3.08
Ectopic expression of BABY BOOM triggers a conversion from vegetative to embryonic growth. Plant Cell (2002) 2.95
Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice. J Exp Med (2007) 2.86
Noninvasive diagnosis of BK virus nephritis by measurement of messenger RNA for BK virus VP1 in urine. Transplantation (2002) 2.86
Deep sequencing of the Camellia sinensis transcriptome revealed candidate genes for major metabolic pathways of tea-specific compounds. BMC Genomics (2011) 2.84
Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs. Proc Natl Acad Sci U S A (2004) 2.66
The abundant NK cells in human secondary lymphoid tissues require activation to express killer cell Ig-like receptors and become cytolytic. J Immunol (2004) 2.64
CLV3 is localized to the extracellular space, where it activates the Arabidopsis CLAVATA stem cell signaling pathway. Plant Cell (2002) 2.52
Prevalence of age-related maculopathy in the adult population in China: the Beijing eye study. Am J Ophthalmol (2006) 2.44
microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma. Blood (2010) 2.37
MicroRNA expression profiles predictive of human renal allograft status. Proc Natl Acad Sci U S A (2009) 2.36
Enhanced salt tolerance mediated by AtHKT1 transporter-induced Na unloading from xylem vessels to xylem parenchyma cells. Plant J (2005) 2.34
Large ventral lateral neurons modulate arousal and sleep in Drosophila. Curr Biol (2008) 2.26
CENP-A, -B, and -C chromatin complex that contains the I-type alpha-satellite array constitutes the prekinetochore in HeLa cells. Mol Cell Biol (2002) 2.11
Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells. Proc Natl Acad Sci U S A (2007) 2.10
Progression of systolic abnormalities in patients with "isolated" diastolic heart failure and diastolic dysfunction. Circulation (2002) 2.09
Would you perform thrombolysis in this acute ischemic stroke patient? Arch Neurol (2009) 2.03
Small molecule activation of PKM2 in cancer cells induces serine auxotrophy. Chem Biol (2012) 1.96
Circadian- and light-dependent regulation of resting membrane potential and spontaneous action potential firing of Drosophila circadian pacemaker neurons. J Neurophysiol (2007) 1.94
Rapamycin is an effective inhibitor of human renal cancer metastasis. Kidney Int (2003) 1.83
The E3 ubiquitin ligase BIG BROTHER controls arabidopsis organ size in a dosage-dependent manner. Curr Biol (2006) 1.77
Localized cutaneous leishmaniasis due to Leishmania donovani and Leishmania tropica: preliminary findings of the study of 161 new cases from a new endemic focus in himachal pradesh, India. Am J Trop Med Hyg (2005) 1.73
AKT/PKB signaling mechanisms in cancer and chemoresistance. Front Biosci (2005) 1.72
Clinical considerations for the development of biosimilars in oncology. MAbs (2015) 1.71
Active establishment of centromeric CENP-A chromatin by RSF complex. J Cell Biol (2009) 1.69
Refractive error in urban and rural adult Chinese in Beijing. Ophthalmology (2005) 1.67
Prevalence of glaucoma in North China: the Beijing Eye Study. Am J Ophthalmol (2010) 1.61
Gut microbial community structure and complications after kidney transplantation: a pilot study. Transplantation (2014) 1.60
Multiplex fluorogenic real-time PCR for detection and quantification of Escherichia coli O157:H7 in dairy wastewater wetlands. Appl Environ Microbiol (2002) 1.60
Tonsilar NK cells restrict B cell transformation by the Epstein-Barr virus via IFN-gamma. PLoS Pathog (2008) 1.60
Serum vascular endothelial growth factor (VEGF) levels correlate with number and location of micrometastases in a murine model of uveal melanoma. Br J Ophthalmol (2010) 1.53
Lymphoproliferative disorders after adult kidney transplant: epidemiology and comparison of registry report with claims-based diagnoses. Am J Kidney Dis (2011) 1.53
Rapid TNFR1-dependent lymphocyte depletion in vivo with a selective chemical inhibitor of IKKbeta. Blood (2006) 1.51
Localized retinal nerve fiber layer defects and arterial hypertension. Am J Hypertens (2013) 1.51
Aryl Hydrocarbon Receptor Activation Down-Regulates IL-7 and Reduces Inflammation in a Mouse Model of DSS-Induced Colitis. Dig Dis Sci (2015) 1.50
Noninvasive prediction of organ graft rejection and outcome using gene expression patterns. Transplantation (2008) 1.50
Noninvasive detection of renal allograft inflammation by measurements of mRNA for IP-10 and CXCR3 in urine. Kidney Int (2004) 1.48
High-sensitivity C-reactive protein predicts target organ damage in Chinese patients with metabolic syndrome. Metabolism (2007) 1.45
Detection of human immunodeficiency virus type 1 DNA in dried blood spots by a duplex real-time PCR assay. J Clin Microbiol (2005) 1.44
Voltammetric study of extracellular dopamine near microdialysis probes acutely implanted in the striatum of the anesthetized rat. J Neurosci Methods (2005) 1.43
Safety and outcomes of intravenous thrombolysis in stroke mimics: a 6-year, single-care center study and a pooled analysis of reported series. Stroke (2011) 1.42
Identification of HIV-1 infected infants and young children using real-time RT PCR and dried blood spots from Uganda and Cameroon. J Virol Methods (2007) 1.39
Comprehensive analysis of CLE polypeptide signaling gene expression and overexpression activity in Arabidopsis. Plant Physiol (2010) 1.39
Cell culture-selected substitutions in influenza A(H3N2) neuraminidase affect drug susceptibility assessment. Antimicrob Agents Chemother (2013) 1.39
Current progress on butyric acid production by fermentation. Curr Microbiol (2009) 1.36
Crystal structures of two subtype N10 neuraminidase-like proteins from bat influenza A viruses reveal a diverged putative active site. Proc Natl Acad Sci U S A (2012) 1.34
Circulating oncometabolite 2-hydroxyglutarate is a potential surrogate biomarker in patients with isocitrate dehydrogenase-mutant intrahepatic cholangiocarcinoma. Clin Cancer Res (2014) 1.33
Rapamycin blocks tumor progression: unlinking immunosuppression from antitumor efficacy. Transplantation (2002) 1.33
Targeting the phosphatidylinositol-3 kinase/Akt pathway for the treatment of cancer. Curr Opin Investig Drugs (2005) 1.31
A spectrum of knock-type Doppler signals in the intracranial vessels. Stroke (2008) 1.31
A pilot randomized clinical safety study of sonothrombolysis augmentation with ultrasound-activated perflutren-lipid microspheres for acute ischemic stroke. Stroke (2008) 1.30
Crystal structure of human SCO1: implications for redox signaling by a mitochondrial cytochrome c oxidase "assembly" protein. J Biol Chem (2005) 1.30
Phosphatase-mediated crosstalk control of ERK and p38 MAPK signaling in corneal epithelial cells. Invest Ophthalmol Vis Sci (2006) 1.29
Exposure to rumen protozoa leads to enhancement of pathogenicity of and invasion by multiple-antibiotic-resistant Salmonella enterica bearing SGI1. Infect Immun (2005) 1.28
Protein kinase activation increases insulin secretion by sensitizing the secretory machinery to Ca2+. J Gen Physiol (2004) 1.26
Reversed Robin Hood syndrome in acute ischemic stroke patients. Stroke (2007) 1.26
Pigment dispersing factor-dependent and -independent circadian locomotor behavioral rhythms. J Neurosci (2008) 1.26
Identification of CD44+CD24+ gastric cancer stem cells. J Cancer Res Clin Oncol (2011) 1.25
Systolic myocardial mechanics in hypertrophic cardiomyopathy: novel concepts and implications for clinical status. J Am Soc Echocardiogr (2008) 1.24
Analysis of fecal microbial flora for antibiotic resistance in ceftiofur-treated calves. Foodborne Pathog Dis (2006) 1.24
Autophagy activation in hepatocellular carcinoma contributes to the tolerance of oxaliplatin via reactive oxygen species modulation. Clin Cancer Res (2011) 1.24
Lack of enteral nutrition--effects on the intestinal immune system. J Surg Res (2005) 1.23
Retracted MicroRNA miR-214 regulates ovarian cancer cell stemness by targeting p53/Nanog. J Biol Chem (2012) 1.22
Ocular axial length and its associations in Chinese: the Beijing Eye Study. PLoS One (2012) 1.22
p37 from Mycoplasma hyorhinis promotes cancer cell invasiveness and metastasis through activation of MMP-2 and followed by phosphorylation of EGFR. Mol Cancer Ther (2008) 1.21
Decline in intestinal mucosal IL-10 expression and decreased intestinal barrier function in a mouse model of total parenteral nutrition. Am J Physiol Gastrointest Liver Physiol (2007) 1.20
Sequence-based prioritization of nonsynonymous single-nucleotide polymorphisms for the study of disease mutations. Am J Hum Genet (2007) 1.20
Gene targeting reveals the role of Oc90 as the essential organizer of the otoconial organic matrix. Dev Biol (2007) 1.19
DEC-205/CD205+ dendritic cells are abundant in the white pulp of the human spleen, including the border region between the red and white pulp. Immunology (2007) 1.19
Development of a unique small molecule modulator of CXCR4. PLoS One (2012) 1.18
Modulation of mitochondrial protein phosphorylation by soluble adenylyl cyclase ameliorates cytochrome oxidase defects. EMBO Mol Med (2009) 1.17
Tacrolimus enhances transforming growth factor-beta1 expression and promotes tumor progression. Transplantation (2003) 1.16
Transient receptor potential vanilloid 1 activation induces inflammatory cytokine release in corneal epithelium through MAPK signaling. J Cell Physiol (2007) 1.16
Tissue-specific, development-dependent phenolic compounds accumulation profile and gene expression pattern in tea plant [Camellia sinensis]. PLoS One (2013) 1.15
MicroRNAs: small RNAs with big effects. Transplantation (2010) 1.15
TRPV1 activation is required for hypertonicity-stimulated inflammatory cytokine release in human corneal epithelial cells. Invest Ophthalmol Vis Sci (2011) 1.15
Sparse feature fidelity for perceptual image quality assessment. IEEE Trans Image Process (2013) 1.14