Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice.

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Published in J Exp Med on January 08, 2007

Authors

Kristin V Tarbell1, Lucine Petit, Xiaopan Zuo, Priscilla Toy, Xunrong Luo, Amina Mqadmi, Hua Yang, Manikkam Suthanthiran, Svetlana Mojsov, Ralph M Steinman

Author Affiliations

1: Laboratory of Cellular Physiology and Immunology and Christopher H. Browne Center for Immunology and Immune Diseases, The Rockefeller University, New York, NY 10021, USA. tarbelk@rockefeller.edu

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Prevalence of glaucoma in North China: the Beijing Eye Study. Am J Ophthalmol (2010) 1.61

Gut microbial community structure and complications after kidney transplantation: a pilot study. Transplantation (2014) 1.60

The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells. J Clin Invest (2008) 1.59

High and low affinity carbohydrate ligands revealed for murine SIGN-R1 by carbohydrate array and cell binding approaches, and differing specificities for SIGN-R3 and langerin. Int Immunol (2004) 1.58

Cell type-dependent retention and transmission of HIV-1 by DC-SIGN. Int Immunol (2003) 1.57

Dendritic cells expand antigen-specific Foxp3+ CD25+ CD4+ regulatory T cells including suppressors of alloreactivity. Immunol Rev (2006) 1.56

Tolerance induced by apoptotic antigen-coupled leukocytes is induced by PD-L1+ and IL-10-producing splenic macrophages and maintained by T regulatory cells. J Immunol (2011) 1.56

Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates. Proc Natl Acad Sci U S A (2011) 1.55

Serum vascular endothelial growth factor (VEGF) levels correlate with number and location of micrometastases in a murine model of uveal melanoma. Br J Ophthalmol (2010) 1.53

Rapid TNFR1-dependent lymphocyte depletion in vivo with a selective chemical inhibitor of IKKbeta. Blood (2006) 1.51

Localized retinal nerve fiber layer defects and arterial hypertension. Am J Hypertens (2013) 1.51