Correlation between promoter hypermethylation of the O6-methylguanine-deoxyribonucleic acid methyltransferase gene and prognosis in patients with high-grade astrocytic tumors treated with surgery, radiotherapy, and 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea-based chemotherapy.

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Published in Neurosurgery on February 01, 2004

Authors

Takanori Kamiryo1, Kenji Tada, Shoji Shiraishi, Naoki Shinojima, Masato Kochi, Yukitaka Ushio

Author Affiliations

1: Department of Neurosurgery, Kumamoto University School of Medicine, Kumamoto, Japan. tkamiryo-nsu@umin.ac.jp

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