Published in Oncogene on August 26, 2004
Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen. PLoS Med (2007) 2.00
BUB1 mediation of caspase-independent mitotic death determines cell fate. J Cell Biol (2007) 1.52
Linking abnormal mitosis to the acquisition of DNA damage. J Cell Biol (2012) 1.48
LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C. PLoS One (2015) 1.42
Caspase-mediated specific cleavage of BubR1 is a determinant of mitotic progression. Mol Cell Biol (2005) 1.21
Downregulation of the anaphase-promoting complex (APC)7 in invasive ductal carcinomas of the breast and its clinicopathologic relationships. Breast Cancer Res (2005) 1.20
An anticlastogenic function for the Polycomb Group gene Bmi1. Proc Natl Acad Sci U S A (2011) 1.17
Stem cells, senescence, neosis and self-renewal in cancer. Cancer Cell Int (2006) 1.11
DNA lesions induced by replication stress trigger mitotic aberration and tetraploidy development. PLoS One (2010) 1.10
Spindle checkpoint function and cellular sensitivity to antimitotic drugs. Mol Cancer Ther (2006) 1.08
Epstein-barr virus-induced resistance to drugs that activate the mitotic spindle assembly checkpoint in Burkitt's lymphoma cells. J Virol (2006) 1.07
Paclitaxel targets FOXM1 to regulate KIF20A in mitotic catastrophe and breast cancer paclitaxel resistance. Oncogene (2015) 1.04
Role of MEK/ERK pathway in the MAD2-mediated cisplatin sensitivity in testicular germ cell tumour cells. Br J Cancer (2006) 0.93
Mad2 and BubR1 modulates tumourigenesis and paclitaxel response in MKN45 gastric cancer cells. Cell Cycle (2014) 0.92
RECQL1 DNA repair helicase: a potential therapeutic target and a proliferative marker against ovarian cancer. PLoS One (2013) 0.91
Functional analysis of HOXD9 in human gliomas and glioma cancer stem cells. Mol Cancer (2011) 0.90
DNA damage-induced cell death is enhanced by progression through mitosis. Cell Cycle (2009) 0.88
Condensin I recruitment and uneven chromatin condensation precede mitotic cell death in response to DNA damage. J Cell Biol (2006) 0.86
Chromosome shattering: a mitotic catastrophe due to chromosome condensation failure. Eur Biophys J (2009) 0.86
RECQL1 and WRN DNA repair helicases: potential therapeutic targets and proliferative markers against cancers. Front Genet (2015) 0.85
Mechanism of cancer cell death induced by depletion of an essential replication regulator. PLoS One (2012) 0.83
The mismatch repair system modulates curcumin sensitivity through induction of DNA strand breaks and activation of G2-M checkpoint. Mol Cancer Ther (2010) 0.83
A synthetic podophyllotoxin derivative exerts anti-cancer effects by inducing mitotic arrest and pro-apoptotic ER stress in lung cancer preclinical models. PLoS One (2013) 0.82
Moscatilin induces apoptosis and mitotic catastrophe in human esophageal cancer cells. J Med Food (2013) 0.80
Antitumor Activity of KW-2450 against Triple-Negative Breast Cancer by Inhibiting Aurora A and B Kinases. Mol Cancer Ther (2015) 0.78
Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis. Clin Exp Gastroenterol (2011) 0.77
Overexpression of the dynein light chain km23-1 in human ovarian carcinoma cells inhibits tumor formation in vivo and causes mitotic delay at prometaphase/metaphase. Int J Cancer (2011) 0.77
Subamolide a induces mitotic catastrophe accompanied by apoptosis in human lung cancer cells. Evid Based Complement Alternat Med (2013) 0.77
A role of the mitotic spindle checkpoint in the cellular response to DNA replication stress. J Cell Biochem (2006) 0.76
The spindle assembly checkpoint: More than just keeping track of the spindle. Trends Cell Mol Biol (2016) 0.75
MAD2γ, a novel MAD2 isoform, reduces mitotic arrest and is associated with resistance in testicular germ cell tumors. Cell Cycle (2016) 0.75
Mitotic Catastrophe in BC3H1 Cells following Yessotoxin Exposure. Front Cell Dev Biol (2017) 0.75
Mitotic vulnerability in triple-negative breast cancer associated with LIN9 is targetable with BET inhibitors. Cancer Res (2017) 0.75
Selective cytotoxicity of vanadium complexes on human pancreatic ductal adenocarcinoma cell line by inducing necroptosis, apoptosis and mitotic catastrophe process. Oncotarget (2017) 0.75
S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial. Lancet Oncol (2008) 11.07
Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. Cell (2003) 5.68
Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice. Science (2012) 4.14
Aurora-A - a guardian of poles. Nat Rev Cancer (2005) 4.11
Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence. Nat Cell Biol (2006) 3.63
Transdifferentiation of glioblastoma cells into vascular endothelial cells. Proc Natl Acad Sci U S A (2011) 3.45
CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth. Cancer Cell (2011) 3.41
Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells. PLoS Biol (2005) 3.33
Roles of polo-like kinase 1 in the assembly of functional mitotic spindles. Curr Biol (2004) 3.29
Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme. Cancer Res (2003) 3.25
HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle. Nature (2012) 3.08
Aurora-A kinase maintains the fidelity of early and late mitotic events in HeLa cells. J Biol Chem (2003) 2.89
Condensin I stabilizes chromosomes mechanically through a dynamic interaction in live cells. Curr Biol (2006) 2.69
Kinetochore stretching inactivates the spindle assembly checkpoint. J Cell Biol (2009) 2.50
M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis. J Exp Med (2009) 2.29
Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. Nat Cell Biol (2010) 2.18
Regulation of sister chromatid cohesion between chromosome arms. Curr Biol (2004) 2.16
RNA interference targeting aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells. Cancer Res (2005) 2.11
Activated macrophages promote Wnt signalling through tumour necrosis factor-alpha in gastric tumour cells. EMBO J (2008) 2.05
Dependence of paclitaxel sensitivity on a functional spindle assembly checkpoint. Cancer Res (2004) 2.03
Mechanism and biological significance of CD44 cleavage. Cancer Sci (2004) 2.00
Chfr is required for tumor suppression and Aurora A regulation. Nat Genet (2005) 1.97
Autophosphorylation of a newly identified site of Aurora-B is indispensable for cytokinesis. J Biol Chem (2004) 1.97
CENP-A phosphorylation by Aurora-A in prophase is required for enrichment of Aurora-B at inner centromeres and for kinetochore function. Dev Cell (2003) 1.91
Cell-matrix interaction via CD44 is independently regulated by different metalloproteinases activated in response to extracellular Ca(2+) influx and PKC activation. J Cell Biol (2004) 1.90
Tumor suppressor WARTS ensures genomic integrity by regulating both mitotic progression and G1 tetraploidy checkpoint function. Oncogene (2004) 1.86
Roles of aurora-A kinase in mitotic entry and G2 checkpoint in mammalian cells. Genes Cells (2002) 1.83
Aurora B controls the association of condensin I but not condensin II with mitotic chromosomes. J Cell Sci (2007) 1.78
Multimodal treatment of ruptured dissecting aneurysms of the vertebral artery during the acute stage. J Neurosurg (2003) 1.76
Induction of ZEB proteins by inactivation of RB protein is key determinant of mesenchymal phenotype of breast cancer. J Biol Chem (2012) 1.72
Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell. Nat Commun (2012) 1.71
NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment. Mol Cell Biol (2006) 1.69
Rb depletion results in deregulation of E-cadherin and induction of cellular phenotypic changes that are characteristic of the epithelial-to-mesenchymal transition. Cancer Res (2008) 1.68
Transcriptional blockade induces p53-dependent apoptosis associated with translocation of p53 to mitochondria. J Biol Chem (2005) 1.67
Real-time in vivo imaging of p16Ink4a reveals cross talk with p53. J Cell Biol (2009) 1.66
Cooperation of HECT-domain ubiquitin ligase hHYD and DNA topoisomerase II-binding protein for DNA damage response. J Biol Chem (2001) 1.62
The UHRF family: oncogenes that are drugable targets for cancer therapy in the near future? Pharmacol Ther (2007) 1.59
Tumor necrosis factor-alpha regulates transforming growth factor-beta-dependent epithelial-mesenchymal transition by promoting hyaluronan-CD44-moesin interaction. J Biol Chem (2009) 1.56
Multiple roles of vertebrate REV genes in DNA repair and recombination. Mol Cell Biol (2005) 1.52
Bilateral pallidal deep brain stimulation in primary Meige syndrome. Parkinsonism Relat Disord (2010) 1.51
Reactive oxygen species-induced autophagic degradation of Helicobacter pylori CagA is specifically suppressed in cancer stem-like cells. Cell Host Microbe (2012) 1.49
Pyruvate kinase M2: multiple faces for conferring benefits on cancer cells. Clin Cancer Res (2012) 1.48
Successful treatment of a ruptured dissecting basilar artery aneurysm. Case report. J Neurosurg (2004) 1.48
Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models. Oncogene (2004) 1.47
Whole-genome sequencing of sake yeast Saccharomyces cerevisiae Kyokai no. 7. DNA Res (2011) 1.45
cAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes. EMBO J (2013) 1.42
Identification of a subunit of a novel Kleisin-beta/SMC complex as a potential substrate of protein phosphatase 2A. Curr Biol (2003) 1.41
The complete removal of cohesin from chromosome arms depends on separase. J Cell Sci (2007) 1.40
MR imaging findings of spinal posterior column involvement in a case of Miller Fisher syndrome. AJNR Am J Neuroradiol (2004) 1.38
Modulation of glucose metabolism by CD44 contributes to antioxidant status and drug resistance in cancer cells. Cancer Res (2012) 1.37
Proteomic analysis of human brain identifies alpha-enolase as a novel autoantigen in Hashimoto's encephalopathy. FEBS Lett (2002) 1.37
Hyaluronan oligosaccharides induce CD44 cleavage and promote cell migration in CD44-expressing tumor cells. J Biol Chem (2003) 1.34
Indications for EMR/ESD in cases of early gastric cancer: relationship between histological type, depth of wall invasion, and lymph node metastasis. Gastric Cancer (2007) 1.32
CD44+ slow-cycling tumor cell expansion is triggered by cooperative actions of Wnt and prostaglandin E2 in gastric tumorigenesis. Cancer Sci (2009) 1.32
KIF1Bbeta functions as a haploinsufficient tumor suppressor gene mapped to chromosome 1p36.2 by inducing apoptotic cell death. J Biol Chem (2008) 1.31
CD44s regulates the TGF-β-mediated mesenchymal phenotype and is associated with poor prognosis in patients with hepatocellular carcinoma. Cancer Res (2012) 1.31
p53 regulates Toll-like receptor 3 expression and function in human epithelial cell lines. Mol Cell Biol (2008) 1.29
The initial phase of chromosome condensation requires Cdk1-mediated phosphorylation of the CAP-D3 subunit of condensin II. Genes Dev (2011) 1.27
Proteolytic cleavage of the CD44 adhesion molecule in multiple human tumors. Am J Pathol (2002) 1.26
Presenilin-dependent gamma-secretase activity mediates the intramembranous cleavage of CD44. Oncogene (2003) 1.24
Down-regulation of nuclear protein ICBP90 by p53/p21Cip1/WAF1-dependent DNA-damage checkpoint signals contributes to cell cycle arrest at G1/S transition. Genes Cells (2004) 1.23
MCAF mediates MBD1-dependent transcriptional repression. Mol Cell Biol (2003) 1.22
Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1. EMBO J (2011) 1.22
DNA damage signaling triggers degradation of histone methyltransferases through APC/C(Cdh1) in senescent cells. Mol Cell (2011) 1.21
Is adenocarcinoma of the esophagogastric junction different between Japan and western countries? The incidence and clinicopathological features at a Japanese high-volume cancer center. World J Surg (2009) 1.20
Maintenance of HCT116 colon cancer cell line conforms to a stochastic model but not a cancer stem cell model. Cancer Sci (2009) 1.20
Spontaneous dissecting aneurysms of anterior and middle cerebral artery associated with brain infarction: a case report and review of the literature. Surg Neurol (2002) 1.19
Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin. Proc Natl Acad Sci U S A (2009) 1.17
Coxsackievirus B3 is an oncolytic virus with immunostimulatory properties that is active against lung adenocarcinoma. Cancer Res (2012) 1.17
Appropriate interval between embolization and surgery in patients with meningioma. AJNR Am J Neuroradiol (2002) 1.15
IGF1 receptor signaling regulates adaptive radioprotection in glioma stem cells. Stem Cells (2013) 1.15
Visualizing the dynamics of p21(Waf1/Cip1) cyclin-dependent kinase inhibitor expression in living animals. Proc Natl Acad Sci U S A (2007) 1.14
RNA-binding protein Musashi1 modulates glioma cell growth through the post-transcriptional regulation of Notch and PI3 kinase/Akt signaling pathways. PLoS One (2012) 1.14
Invasion precedes tumor mass formation in a malignant brain tumor model of genetically modified neural stem cells. Neoplasia (2011) 1.14
xCT inhibition depletes CD44v-expressing tumor cells that are resistant to EGFR-targeted therapy in head and neck squamous cell carcinoma. Cancer Res (2013) 1.13