Published in Pharmacol Biochem Behav on February 01, 2004
Agmatine reduces extracellular glutamate during pentylenetetrazole-induced seizures in rat brain: a potential mechanism for the anticonvulsive effects. Neurosci Lett (2005) 0.93
Expression of arginine decarboxylase in brain regions and neuronal cells. J Neurochem (2006) 0.90
Agmatine: biological role and therapeutic potentials in morphine analgesia and dependence. AAPS J (2006) 0.88
Agmatine enhances the anticonvulsant action of phenobarbital and valproate in the mouse maximal electroshock seizure model. J Neural Transm (Vienna) (2008) 0.86
High dosage of agmatine alleviates pentylenetetrazole-induced chronic seizures in rats possibly by exerting an anticonvulsive effect. Exp Ther Med (2014) 0.78
High dosage of cannabidiol (CBD) alleviates pentylenetetrazole-induced epilepsy in rats by exerting an anticonvulsive effect. Int J Clin Exp Med (2015) 0.77
Retroviral expression of human arginine decarboxylase reduces oxidative stress injury in mouse cortical astrocytes. BMC Neurosci (2014) 0.76
Millions of years of evolution preserved: a comprehensive catalog of the processed pseudogenes in the human genome. Genome Res (2003) 5.49
Multicenter randomized controlled trial of percutaneous cryoablation versus radiofrequency ablation in hepatocellular carcinoma. Hepatology (2015) 2.81
The long rather than the short allele of 5-HTTLPR predisposes Han Chinese to anxiety and reduced connectivity between prefrontal cortex and amygdala. Neurosci Bull (2013) 2.78
HLA class II polymorphisms associated with the physiologic characteristics defined by Traditional Chinese Medicine: linking modern genetics with an ancient medicine. J Altern Complement Med (2007) 2.61
KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma. Cancer Cell (2012) 2.55
Complicated acute type B dissection: is surgery still the best option?: a report from the International Registry of Acute Aortic Dissection. JACC Cardiovasc Interv (2008) 2.47
Pax6 is a human neuroectoderm cell fate determinant. Cell Stem Cell (2010) 2.46
KRAS mutations and resistance to EGFR-TKIs treatment in patients with non-small cell lung cancer: a meta-analysis of 22 studies. Lung Cancer (2009) 2.27
COLD-PCR-enhanced high-resolution melting enables rapid and selective identification of low-level unknown mutations. Clin Chem (2009) 2.17
PSORS2 is due to mutations in CARD14. Am J Hum Genet (2012) 2.10
Glucocorticoids promote hepatic cholestasis in mice by inhibiting the transcriptional activity of the farnesoid X receptor. Gastroenterology (2012) 2.05
Molecular characterization of meiotic recombination across the 140-kb multigenic a1-sh2 interval of maize. Proc Natl Acad Sci U S A (2002) 1.98
miR-7 suppresses brain metastasis of breast cancer stem-like cells by modulating KLF4. Cancer Res (2013) 1.94
On evaluating molecular-docking methods for pose prediction and enrichment factors. J Chem Inf Model (2006) 1.90
Impact of duty hours restrictions on quality of care and clinical outcomes. Am J Med (2007) 1.81
Cediranib plus FOLFOX/CAPOX versus placebo plus FOLFOX/CAPOX in patients with previously untreated metastatic colorectal cancer: a randomized, double-blind, phase III study (HORIZON II). J Clin Oncol (2012) 1.73
Intermolecular failure of L-type Ca2+ channel and ryanodine receptor signaling in hypertrophy. PLoS Biol (2007) 1.70
PCR-based methods for the enrichment of minority alleles and mutations. Clin Chem (2009) 1.65
Polymorphisms in the XPG gene and risk of gastric cancer in Chinese populations. Hum Genet (2012) 1.64
YN968D1 is a novel and selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase with potent activity in vitro and in vivo. Cancer Sci (2011) 1.53
Traumatic brain injury alters expression of hippocampal microRNAs: potential regulators of multiple pathophysiological processes. J Neurosci Res (2009) 1.48
SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell. J Mol Cell Biol (2011) 1.48
Heterodimerization and cross-desensitization between the mu-opioid receptor and the chemokine CCR5 receptor. Eur J Pharmacol (2004) 1.45
Kinase peptide specificity: improved determination and relevance to protein phosphorylation. Proc Natl Acad Sci U S A (2004) 1.43
Observation of microsphere movement driven by optical pulse. Opt Lett (2011) 1.42
Phospholipase C-mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane. J Cell Biol (2009) 1.41
Bevacizumab plus capecitabine and cisplatin in Chinese patients with inoperable locally advanced or metastatic gastric or gastroesophageal junction cancer: randomized, double-blind, phase III study (AVATAR study). Gastric Cancer (2014) 1.41
Role of age in acute type A aortic dissection outcome: report from the International Registry of Acute Aortic Dissection (IRAD). J Thorac Cardiovasc Surg (2010) 1.41
LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation. Proc Natl Acad Sci U S A (2009) 1.39
Ice-COLD-PCR enables rapid amplification and robust enrichment for low-abundance unknown DNA mutations. Nucleic Acids Res (2010) 1.38
Microemulsion-based hydrogel formulation of ibuprofen for topical delivery. Int J Pharm (2006) 1.37
Do we really need closed-suction drainage in total hip arthroplasty? A meta-analysis. Int Orthop (2013) 1.35
Retrospective survey of 452 patients with inflammatory bowel disease in Wuhan city, central China. Inflamm Bowel Dis (2006) 1.32
Genetic variations of mTORC1 genes and risk of gastric cancer in an Eastern Chinese population. Mol Carcinog (2013) 1.32
Large sample size, wide variant spectrum, and advanced machine-learning technique boost risk prediction for inflammatory bowel disease. Am J Hum Genet (2013) 1.31
A single pair of acidic residues in the kinase major groove mediates strong substrate preference for P-2 or P-5 arginine in the AGC, CAMK, and STE kinase families. J Biol Chem (2005) 1.28
First prospective, population-based inflammatory bowel disease incidence study in mainland of China: the emergence of "western" disease. Inflamm Bowel Dis (2013) 1.25
Deregulation of cdk5, hyperphosphorylation, and cytoskeletal pathology in the Niemann-Pick type C murine model. J Neurosci (2002) 1.24
Simultaneously typing nine serotypes of enteroviruses associated with hand, foot, and mouth disease by a GeXP analyzer-based multiplex reverse transcription-PCR assay. J Clin Microbiol (2011) 1.23
Multicenter phase II study of apatinib, a novel VEGFR inhibitor in heavily pretreated patients with metastatic triple-negative breast cancer. Int J Cancer (2014) 1.22
Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis. J Neurosci (2013) 1.22
CpG-modified plasmid DNA encoding flagellin improves immunogenicity and provides protection against Burkholderia pseudomallei infection in BALB/c mice. Infect Immun (2006) 1.21
Do we really need tranexamic acid in total hip arthroplasty? A meta-analysis of nineteen randomized controlled trials. Arch Orthop Trauma Surg (2013) 1.20
Vav3 oncogene is overexpressed and regulates cell growth and androgen receptor activity in human prostate cancer. Mol Endocrinol (2006) 1.20
Oxidative lipidomics of hyperoxic acute lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation. Am J Physiol Lung Cell Mol Physiol (2010) 1.19
YQA14: a novel dopamine D3 receptor antagonist that inhibits cocaine self-administration in rats and mice, but not in D3 receptor-knockout mice. Addict Biol (2011) 1.16
Predictive and prognostic value of KRAS mutations in metastatic colorectal cancer patients treated with cetuximab: a meta-analysis of 22 studies. Eur J Cancer (2010) 1.16
Cyclic RGD conjugated poly(ethylene glycol)-co-poly(lactic acid) micelle enhances paclitaxel anti-glioblastoma effect. J Control Release (2010) 1.15
Adapalene-benzoyl peroxide, a fixed-dose combination for the treatment of acne vulgaris: results of a multicenter, randomized double-blind, controlled study. J Am Acad Dermatol (2007) 1.15
Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer. BMC Cancer (2008) 1.14
Depression and associated factors in internal migrant workers in China. J Affect Disord (2011) 1.13
Computer-assisted orbital volume measurement in the surgical correction of late enophthalmos caused by blowout fractures. Ophthal Plast Reconstr Surg (2003) 1.13
The membrane-proximal region of vesicular stomatitis virus glycoprotein G ectodomain is critical for fusion and virus infectivity. J Virol (2003) 1.13
Cyclin-dependent kinase inhibitors attenuate protein hyperphosphorylation, cytoskeletal lesion formation, and motor defects in Niemann-Pick Type C mice. Am J Pathol (2004) 1.12
Potentially functional variants of PLCE1 identified by GWASs contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population. PLoS One (2012) 1.12
A North American study of adapalene-benzoyl peroxide combination gel in the treatment of acne. Cutis (2009) 1.11
Prediction of microRNAs associated with human diseases based on weighted k most similar neighbors. PLoS One (2013) 1.11
MicroRNA-1285 inhibits the expression of p53 by directly targeting its 3' untranslated region. Biochem Biophys Res Commun (2010) 1.10
Reactive astrocytes promote the metastatic growth of breast cancer stem-like cells by activating Notch signalling in brain. EMBO Mol Med (2013) 1.10
Circulating microRNAs: a novel class of potential biomarkers for diagnosing and prognosing central nervous system diseases. Cell Mol Neurobiol (2013) 1.09
Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling. Annu Rev Immunol (2015) 1.08
Multiple aneurysms of distal anterior cerebral artery associated with a cerebral arteriovenous malformation. Neurol India (2010) 1.08
BMI1 and Mel-18 oppositely regulate carcinogenesis and progression of gastric cancer. Mol Cancer (2010) 1.08
Soluble CD14: genomewide association analysis and relationship to cardiovascular risk and mortality in older adults. Arterioscler Thromb Vasc Biol (2012) 1.08
Thermal stability and inactivation of hepatitis C virus grown in cell culture. Virol J (2010) 1.07
Murine coronavirus induces type I interferon in oligodendrocytes through recognition by RIG-I and MDA5. J Virol (2010) 1.07
Incorporating prior knowledge into Gene Network Study. Bioinformatics (2013) 1.06
Compact designer TALENs for efficient genome engineering. Nat Commun (2013) 1.06
Exceptional disfavor for proline at the P + 1 position among AGC and CAMK kinases establishes reciprocal specificity between them and the proline-directed kinases. J Biol Chem (2005) 1.06
Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation. J Immunol (2010) 1.06
DNA degradation test predicts success in whole-genome amplification from diverse clinical samples. J Mol Diagn (2007) 1.05
mHealthApps: A Repository and Database of Mobile Health Apps. JMIR Mhealth Uhealth (2015) 1.05
An update on chemotherapy of colorectal liver metastases. World J Gastroenterol (2012) 1.05
Polymorphisms in ERCC1 and XPF genes and risk of gastric cancer in an eastern Chinese population. PLoS One (2012) 1.05
Attenuated expression of xeroderma pigmentosum group C is associated with critical events in human bladder cancer carcinogenesis and progression. Cancer Res (2007) 1.05
Late reconstruction of the complex orbital fractures with computer-aided design and computer-aided manufacturing technique. J Craniofac Surg (2007) 1.05
Comparative transcriptional profiling and preliminary study on heterosis mechanism of super-hybrid rice. Mol Plant (2010) 1.05
Primary treatment of acute dacryocystitis by endoscopic dacryocystorhinostomy with silicone intubation guided by a soft probe. Ophthalmology (2009) 1.05
Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis. Circulation (2008) 1.05
Statins: multiple neuroprotective mechanisms in neurodegenerative diseases. Exp Neurol (2010) 1.04
Characteristics of fecal and mucosa-associated microbiota in Chinese patients with inflammatory bowel disease. Medicine (Baltimore) (2014) 1.03
A pH-responsive cyclodextrin-based hybrid nanosystem as a nonviral vector for gene delivery. Biomaterials (2013) 1.03
TNF gene polymorphisms and Helicobacter Pylori infection in gastric carcinogenesis in Chinese population. Am J Gastroenterol (2005) 1.03
Present status and perspectives of colorectal cancer in Asia: Colorectal Cancer Working Group report in 30th Asia-Pacific Cancer Conference. Jpn J Clin Oncol (2010) 1.03
Clinical pharmacokinetics, metabolism, and drug-drug interaction of carfilzomib. Drug Metab Dispos (2012) 1.02
Suppression of coronavirus replication by inhibition of the MEK signaling pathway. J Virol (2006) 1.01
Possibilities and potential roles of estrogen in the pathogenesis of proliferation hemangiomas formation. Med Hypotheses (2008) 1.01
Serotonin transporter gene-linked polymorphic region (5-HTTLPR) influences decision making under ambiguity and risk in a large Chinese sample. Neuropharmacology (2010) 1.01
Protein kinase specificity. A strategic collaboration between kinase peptide specificity and substrate recruitment. Cell Cycle (2005) 1.01
Neurabin scaffolding of adenosine receptor and RGS4 regulates anti-seizure effect of endogenous adenosine. J Neurosci (2012) 1.00
Diurnal rhythm of apolipoprotein A-IV in rat hypothalamus and its relation to food intake and corticosterone. Endocrinology (2004) 1.00
Selective hydrogenation by Pd nanoparticles embedded in polyelectrolyte multilayers. J Am Chem Soc (2004) 1.00
Multicenter phase II study of apatinib in non-triple-negative metastatic breast cancer. BMC Cancer (2014) 0.99
Oncogenic role of the chromobox protein CBX7 in gastric cancer. J Exp Clin Cancer Res (2010) 0.99
Unequal sister chromatid and homolog recombination at a tandem duplication of the A1 locus in maize. Genetics (2006) 0.99
Does simplicity compromise accuracy in ACS risk prediction? A retrospective analysis of the TIMI and GRACE risk scores. PLoS One (2009) 0.99
Icaritin shows potent anti-leukemia activity on chronic myeloid leukemia in vitro and in vivo by regulating MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings. PLoS One (2011) 0.98
Oxidative stress-mediated up-regulation of myocardial ischemic preconditioning up-regulated protein 1 gene expression in H9c2 cardiomyocytes is regulated by cyclic AMP-response element binding protein. Free Radic Biol Med (2010) 0.98
Simultaneous determination of stilbenes, phenolic acids, flavonoids and anthraquinones in Radix polygoni multiflori by LC-MS/MS. J Pharm Biomed Anal (2011) 0.98