Published in Environ Health Perspect on February 01, 2004
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Prenatal exposure to the environmental obesogen tributyltin predisposes multipotent stem cells to become adipocytes. Mol Endocrinol (2010) 1.84
Bisphenol A and its analogues activate human pregnane X receptor. Environ Health Perspect (2012) 1.81
Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. J Clin Invest (2006) 1.75
Vitamin K2 regulation of bone homeostasis is mediated by the steroid and xenobiotic receptor SXR. J Biol Chem (2003) 1.69
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Triflumizole is an obesogen in mice that acts through peroxisome proliferator activated receptor gamma (PPARγ). Environ Health Perspect (2012) 1.63
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The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism. Nucl Recept Signal (2009) 1.41
Minireview: PPARγ as the target of obesogens. J Steroid Biochem Mol Biol (2011) 1.40
Shape signatures: a new approach to computer-aided ligand- and receptor-based drug design. J Med Chem (2003) 1.39
Human pregnane X receptor antagonists and agonists define molecular requirements for different binding sites. Mol Pharmacol (2007) 1.39
Minireview: the case for obesogens. Mol Endocrinol (2009) 1.33
Steroid and xenobiotic receptor SXR mediates vitamin K2-activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells. J Biol Chem (2006) 1.33
Learning from and about others: towards using imitation to bootstrap the social understanding of others by robots. Artif Life (2005) 1.28
Expression of the steroid and xenobiotic receptor and its possible target gene, organic anion transporting polypeptide-A, in human breast carcinoma. Cancer Res (2006) 1.26
Detecting hidden sequence propensity for amyloid fibril formation. Protein Sci (2004) 1.25
DNA microarray data imputation and significance analysis of differential expression. Bioinformatics (2005) 1.24
The obesogenic effect of high fructose exposure during early development. Nat Rev Endocrinol (2013) 1.23
New predictive models for blood-brain barrier permeability of drug-like molecules. Pharm Res (2008) 1.20
The environmental obesogen tributyltin chloride acts via peroxisome proliferator activated receptor gamma to induce adipogenesis in murine 3T3-L1 preadipocytes. J Steroid Biochem Mol Biol (2011) 1.17
Steroid and xenobiotic receptor (SXR), cytochrome P450 3A4 and multidrug resistance gene 1 in human adult and fetal tissues. Mol Cell Endocrinol (2005) 1.15
Highly potent triazole-based tubulin polymerization inhibitors. J Med Chem (2007) 1.13
Benzoate X receptors alpha and beta are pharmacologically distinct and do not function as xenobiotic receptors. J Biol Chem (2002) 1.11
Improved method for predicting beta-turn using support vector machine. Bioinformatics (2005) 1.10
Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. Drug Metab Dispos (2004) 1.09
Evolving carbapenemases: can medicinal chemists advance one step ahead of the coming storm? J Med Chem (2010) 1.09
Active repression by unliganded retinoid receptors in development: less is sometimes more. J Cell Biol (2003) 1.08
Retinoic acid signaling in the brain marks formation of optic projections, maturation of the dorsal telencephalon, and function of limbic sites. J Comp Neurol (2004) 1.08
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Bisphenol A diglycidyl ether induces adipogenic differentiation of multipotent stromal stem cells through a peroxisome proliferator-activated receptor gamma-independent mechanism. Environ Health Perspect (2012) 1.07
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Inhibition of human liver catechol-O-methyltransferase by tea catechins and their metabolites: structure-activity relationship and molecular-modeling studies. Biochem Pharmacol (2005) 1.04
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Quantitative structure-activity relationship methods: perspectives on drug discovery and toxicology. Environ Toxicol Chem (2003) 1.03
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Characterizing genetic variants for clinical action. Am J Med Genet C Semin Med Genet (2014) 1.02
Activation of the steroid and xenobiotic receptor, SXR, induces apoptosis in breast cancer cells. BMC Cancer (2009) 1.02
Shape signatures: new descriptors for predicting cardiotoxicity in silico. Chem Res Toxicol (2008) 1.01
Using surrogate modeling in the prediction of fibrinogen adsorption onto polymer surfaces. J Chem Inf Comput Sci (2004) 1.00
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Homology model of the CB1 cannabinoid receptor: sites critical for nonclassical cannabinoid agonist interaction. Biopolymers (2003) 0.99
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Computational discovery of novel low micromolar human pregnane X receptor antagonists. Mol Pharmacol (2008) 0.98
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Myeloid-specific IκB kinase β deficiency decreases atherosclerosis in low-density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol (2012) 0.98
Wavelet analysis of DNA walks. J Comput Biol (2006) 0.98
Carbohydrate composition of amphiphilic macromolecules influences physicochemical properties and binding to atherogenic scavenger receptor A. Acta Biomater (2012) 0.97
Deficiency of PXR decreases atherosclerosis in apoE-deficient mice. J Lipid Res (2011) 0.96
A new approach to the rationale discovery of polymeric biomaterials. Biomaterials (2007) 0.96
Expression levels and activation of a PXR variant are directly related to drug resistance in osteosarcoma cell lines. Cancer (2007) 0.96
Activation of steroid and xenobiotic receptor (SXR, NR1I2) and its orthologs in laboratory, toxicologic, and genome model species. Environ Health Perspect (2008) 0.95
Development and application of hybrid structure based method for efficient screening of ligands binding to G-protein coupled receptors. J Comput Aided Mol Des (2006) 0.95
Designing green oxidation catalysts for purifying environmental waters. J Am Chem Soc (2010) 0.93
Novel microtubule polymerization inhibitor with potent antiproliferative and antitumor activity. Cancer Res (2009) 0.93
Identification of a minimal subset of receptor conformations for improved multiple conformation docking and two-step scoring. J Chem Inf Comput Sci (2004) 0.93
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Specific interactions between the viral coreceptor CXCR4 and the biguanide-based compound NB325 mediate inhibition of human immunodeficiency virus type 1 infection. Antimicrob Agents Chemother (2008) 0.89
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