Published in J Biochem Mol Biol on January 31, 2004
The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse. Nucleic Acids Res (2006) 3.40
Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research. Behav Brain Res (2008) 1.14
Controlling complexity: the clinical relevance of mouse complex genetics. Eur J Hum Genet (2013) 0.92
Probing human cardiovascular congenital disease using transgenic mouse models. Prog Mol Biol Transl Sci (2011) 0.81
Intracellular proadrenomedullin-derived peptides decorate the microtubules and contribute to cytoskeleton function. Endocrinology (2008) 0.81
Differential antigen processing by dendritic cell subsets in vivo. Science (2007) 8.42
Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation. Nat Genet (2006) 4.43
Knockout mice created by TALEN-mediated gene targeting. Nat Biotechnol (2013) 4.31
Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases. Genome Res (2013) 2.28
Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation. Nat Genet (2003) 1.57
Adrenal peripheral clock controls the autonomous circadian rhythm of glucocorticoid by causing rhythmic steroid production. Proc Natl Acad Sci U S A (2008) 1.46
Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis. EMBO J (2009) 1.45
Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti-human DEC205 monoclonal antibody. Blood (2010) 1.40
Inhibition of translation and induction of apoptosis by Bunyaviral nonstructural proteins bearing sequence similarity to reaper. Mol Biol Cell (2003) 1.32
Assurance of mitochondrial integrity and mammalian longevity by the p62-Keap1-Nrf2-Nqo1 cascade. EMBO Rep (2012) 1.25
Cyst formation in kidney via B-Raf signaling in the PKD2 transgenic mice. J Biol Chem (2008) 1.24
Telomeres and telomerase in aging, regeneration and cancer. Mol Cells (2003) 1.22
West Nile virus capsid protein induces p53-mediated apoptosis via the sequestration of HDM2 to the nucleolus. Cell Microbiol (2007) 1.18
Ectopic expression of the catalytic subunit of telomerase protects against brain injury resulting from ischemia and NMDA-induced neurotoxicity. J Neurosci (2004) 1.17
Jab1 induces the cytoplasmic localization and degradation of p53 in coordination with Hdm2. J Biol Chem (2006) 1.14
Aerosol delivery of urocanic acid-modified chitosan/programmed cell death 4 complex regulated apoptosis, cell cycle, and angiogenesis in lungs of K-ras null mice. Mol Cancer Ther (2006) 1.09
Acceleration of gastric tumorigenesis through MKRN1-mediated posttranslational regulation of p14ARF. J Natl Cancer Inst (2012) 1.07
Multiple developmental defects derived from impaired recruitment of ASC-2 to nuclear receptors in mice: implication for posterior lenticonus with cataract. Mol Cell Biol (2002) 1.07
Jab1 mediates cytoplasmic localization and degradation of West Nile virus capsid protein. J Biol Chem (2006) 1.06
Ubiquitination and degradation of the FADD adaptor protein regulate death receptor-mediated apoptosis and necroptosis. Nat Commun (2012) 1.06
The roles of FADD in extrinsic apoptosis and necroptosis. BMB Rep (2012) 1.03
Inhibition of colon tumor progression and angiogenesis by the Ink4a/Arf locus. Cancer Res (2003) 1.00
Chromatin remodeling complex interacts with ADD1/SREBP1c to mediate insulin-dependent regulation of gene expression. Mol Cell Biol (2006) 0.98
Telomerase deficiency affects normal brain functions in mice. Neurochem Res (2009) 0.98
Mouse genetics: catalogue and scissors. BMB Rep (2012) 0.97
Extratelomeric functions of telomerase. Curr Mol Med (2005) 0.97
Short dysfunctional telomeres impair the repair of arsenite-induced oxidative damage in mouse cells. J Cell Physiol (2008) 0.96
Dynamic rearrangement of telomeres during spermatogenesis in mice. Dev Biol (2005) 0.96
MKRN1 induces degradation of West Nile virus capsid protein by functioning as an E3 ligase. J Virol (2010) 0.95
STAT3 silencing enhances the efficacy of the HSV.tk suicide gene in gastrointestinal cancer therapy. Clin Exp Metastasis (2012) 0.94
Loss of extracellular superoxide dismutase induces severe IL-23-mediated skin inflammation in mice. J Invest Dermatol (2012) 0.92
The role of Ink4a/Arf in ErbB2 mammary gland tumorigenesis. Cancer Res (2003) 0.91
The pleiotropy of telomerase against cell death. Mol Cells (2005) 0.91
Jab1 as a mediator of nuclear export and cytoplasmic degradation of p53. Mol Cells (2006) 0.91
Interferon regulatory factor-1 (IRF-1) is a mediator for interferon-gamma induced attenuation of telomerase activity and human telomerase reverse transcriptase (hTERT) expression. Oncogene (2003) 0.90
PML-IV functions as a negative regulator of telomerase by interacting with TERT. J Cell Sci (2009) 0.89
Galectin-3 activates PPARγ and supports white adipose tissue formation and high-fat diet-induced obesity. Endocrinology (2015) 0.89
TCR-independent and caspase-independent apoptosis of murine thymocytes by CD24 cross-linking. J Immunol (2004) 0.86
A strong candidate gene for the Papg1 locus on mouse chromosome 4 affecting lung tumor progression. Oncogene (2002) 0.86
Synchronous activation of gonadotropin-releasing hormone gene transcription and secretion by pulsatile kisspeptin stimulation. Proc Natl Acad Sci U S A (2013) 0.85
Targeting Notch signaling by γ-secretase inhibitor I enhances the cytotoxic effect of 5-FU in gastric cancer. Clin Exp Metastasis (2015) 0.85
Oncogenic potential of a dominant negative mutant of interferon regulatory factor 3. J Biol Chem (2003) 0.85
Essential role of p53 in TPEN-induced neuronal apoptosis. FEBS Lett (2009) 0.85
Hsp70 functions as a negative regulator of West Nile virus capsid protein through direct interaction. Biochem Biophys Res Commun (2006) 0.84
MafK positively regulates NF-κB activity by enhancing CBP-mediated p65 acetylation. Sci Rep (2013) 0.84
Inactivation of Mxi1 induces Il-8 secretion activation in polycystic kidney. Biochem Biophys Res Commun (2007) 0.83
The multifaceted factor peroxisome proliferator-activated receptor γ (PPARγ) in metabolism, immunity, and cancer. Arch Pharm Res (2015) 0.82
EI24 regulates epithelial-to-mesenchymal transition and tumor progression by suppressing TRAF2-mediated NF-κB activity. Oncotarget (2013) 0.82
Transgenic overexpression of p23 induces spontaneous hydronephrosis in mice. Int J Exp Pathol (2011) 0.81
Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation. Mol Cells (2003) 0.81
Mouse models for telomere and telomerase biology. Exp Mol Med (2003) 0.81
An analysis of an interactome for apoptosis factor, Ei24/PIG8, using the inducible expression system and shotgun proteomics. J Proteome Res (2010) 0.81
Sensitizing effects of cadmium on TNF-alpha- and TRAIL-mediated apoptosis of NIH3T3 cells with distinct expression patterns of p53. Carcinogenesis (2002) 0.80
Pierce1, a novel p53 target gene contributing to the ultraviolet-induced DNA damage response. Cancer Res (2010) 0.80
Hes6 controls cell proliferation via interaction with cAMP-response element-binding protein-binding protein in the promyelocytic leukemia nuclear body. J Biol Chem (2007) 0.80
Anti-cancer effect of a quinoxaline derivative GK13 as a transglutaminase 2 inhibitor. J Cancer Res Clin Oncol (2013) 0.80
Air quality during demolition and recovery activities in post-Katrina New Orleans. Environ Toxicol Chem (2010) 0.79
Ei24-deficiency attenuates protein kinase Cα signaling and skin carcinogenesis in mice. Int J Biochem Cell Biol (2012) 0.79
Role of INK4a locus in normal eye development and cataract genesis. Mech Ageing Dev (2006) 0.79
Up-regulation of Idh3alpha causes reduction of neuronal differentiation in PC12 cells. BMB Rep (2010) 0.78
Differentiation of West Nile virus-infected animals from vaccinated animals by competitive ELISA using monoclonal antibodies against non-structural protein 1. Vector Borne Zoonotic Dis (2012) 0.78
Identification of a novel Rb-regulated gene associated with the cell cycle. Mol Cells (2007) 0.78
Analysis of 41 cancer cell lines reveals excessive allelic loss and novel mutations in the SIRT1 gene. Cell Cycle (2012) 0.78
Mxi1 regulates cell proliferation through insulin-like growth factor binding protein-3. Biochem Biophys Res Commun (2011) 0.77
Ei24, a novel E2F target gene, affects p53-independent cell death upon ultraviolet C irradiation. J Biol Chem (2013) 0.77
Clinical implications of antitelomeric drugs with respect to the nontelomeric functions of telomerase in cancer. Onco Targets Ther (2013) 0.77
Hematopoietic malignancies associated with increased Stat5 and Bcl-x(L) expressions in Ink4a/Arf-deficient mice. Mech Ageing Dev (2005) 0.76
Jab1 has negative effects on p53-mediated genotoxic stresses. BMB Rep (2009) 0.76
Extracting extra-telomeric phenotypes from telomerase mouse models. Yonsei Med J (2014) 0.76
Atrophy of brown adipocytes in the adult mouse causes transformation into white adipocyte-like cells. Exp Mol Med (2003) 0.75
Insertional mutation in the intron 1 of Unc5h3 gene induces ataxic, lean and hyperactive phenotype in mice. Exp Anim (2003) 0.75
2,2',4,6,6'-Pentachlorobiphenyl induces mitotic arrest and p53 activation. Toxicol Sci (2004) 0.75
Generation of reversible Rb-knockdown mice. Mech Ageing Dev (2005) 0.75