Published in Radiology on February 05, 2004
MR thermometry. J Magn Reson Imaging (2008) 4.43
Pulsed-high intensity focused ultrasound and low temperature-sensitive liposomes for enhanced targeted drug delivery and antitumor effect. Clin Cancer Res (2007) 2.17
Ultrasound mediated delivery of drugs and genes to solid tumors. Adv Drug Deliv Rev (2008) 1.93
Accurate temperature imaging based on intermolecular coherences in magnetic resonance. Science (2008) 1.20
Thermosensitive liposomal drug delivery systems: state of the art review. Int J Nanomedicine (2014) 0.96
Overcoming the concentration-dependence of responsive probes for magnetic resonance imaging. Metallomics (2015) 0.91
Adapting MRI acoustic radiation force imaging for in vivo human brain focused ultrasound applications. Magn Reson Med (2012) 0.89
Establishing a rabbit model of malignant esophagostenosis using the endoscopic implantation technique for studies on stent innovation. J Transl Med (2014) 0.82
A method to convert MRI images of temperature change into images of absolute temperature in solid tumours. Int J Hyperthermia (2013) 0.79
Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption. Proc Natl Acad Sci U S A (2006) 3.70
Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI-guided focused ultrasound. Int J Cancer (2007) 3.21
Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications. Neuroimage (2005) 3.17
Transcranial magnetic resonance imaging- guided focused ultrasound surgery of brain tumors: initial findings in 3 patients. Neurosurgery (2010) 3.15
MR imaging-guided focused ultrasound surgery of uterine leiomyomas: a feasibility study. Radiology (2003) 3.07
Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles. Ultrasound Med Biol (2004) 2.76
Chemotherapy delivery issues in central nervous system malignancy: a reality check. J Clin Oncol (2007) 2.66
Temporary disruption of the blood-brain barrier by use of ultrasound and microbubbles: safety and efficacy evaluation in rhesus macaques. Cancer Res (2012) 2.60
Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. J Neurosurg (2006) 2.58
MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits. Ultrasound Med Biol (2005) 2.57
Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium. Ultrasound Med Biol (2008) 2.47
MR-guided focused ultrasound thalamotomy for essential tremor: a proof-of-concept study. Lancet Neurol (2013) 2.37
Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasound. Biochem Biophys Res Commun (2005) 2.28
Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index. Ultrasound Med Biol (2008) 2.17
500-element ultrasound phased array system for noninvasive focal surgery of the brain: a preliminary rabbit study with ex vivo human skulls. Magn Reson Med (2004) 2.13
TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors. J Clin Oncol (2004) 2.09
Ultrasound-mediated cavitation thresholds of liquid perfluorocarbon droplets in vitro. Ultrasound Med Biol (2003) 2.07
Effects of acoustic parameters and ultrasound contrast agent dose on focused-ultrasound induced blood-brain barrier disruption. Ultrasound Med Biol (2008) 2.03
Antibodies targeted to the brain with image-guided focused ultrasound reduces amyloid-beta plaque load in the TgCRND8 mouse model of Alzheimer's disease. PLoS One (2010) 2.03
The neurotropic parasite Toxoplasma gondii increases dopamine metabolism. PLoS One (2011) 1.98
Ultrasound enhanced delivery of molecular imaging and therapeutic agents in Alzheimer's disease mouse models. PLoS One (2008) 1.95
Uterine leiomyomas: MR imaging-guided focused ultrasound surgery--results of different treatment protocols. Radiology (2007) 1.90
Uterine leiomyomas: MR imaging-based thermometry and thermal dosimetry during focused ultrasound thermal ablation. Radiology (2006) 1.89
Localized harmonic motion imaging: theory, simulations and experiments. Ultrasound Med Biol (2003) 1.74
Microbubble contrast agent with focused ultrasound to create brain lesions at low power levels: MR imaging and histologic study in rabbits. Radiology (2006) 1.71
Magnetic resonance image-guided focused ultrasound surgery. Cancer J (2002) 1.70
Alzheimer disease in a mouse model: MR imaging-guided focused ultrasound targeted to the hippocampus opens the blood-brain barrier and improves pathologic abnormalities and behavior. Radiology (2014) 1.68
Blood-brain barrier: real-time feedback-controlled focused ultrasound disruption by using an acoustic emissions-based controller. Radiology (2012) 1.64
Use of ultrasound pulses combined with Definity for targeted blood-brain barrier disruption: a feasibility study. Ultrasound Med Biol (2007) 1.63
Multiphoton imaging of ultrasound/Optison mediated cerebrovascular effects in vivo. J Cereb Blood Flow Metab (2006) 1.60
Delivery of AAV-IGF-1 to the CNS extends survival in ALS mice through modification of aberrant glial cell activity. Mol Ther (2008) 1.57
Overview of therapeutic ultrasound applications and safety considerations. J Ultrasound Med (2012) 1.54
The threshold for brain damage in rabbits induced by bursts of ultrasound in the presence of an ultrasound contrast agent (Optison). Ultrasound Med Biol (2003) 1.53
MR imaging-controlled focused ultrasound ablation: a noninvasive image-guided surgery. Magn Reson Imaging Clin N Am (2005) 1.52
Focused ultrasound surgery in oncology: overview and principles. Radiology (2011) 1.51
Brain arterioles show more active vesicular transport of blood-borne tracer molecules than capillaries and venules after focused ultrasound-evoked opening of the blood-brain barrier. Ultrasound Med Biol (2006) 1.49
MRI investigation of the threshold for thermally induced blood-brain barrier disruption and brain tissue damage in the rabbit brain. Magn Reson Med (2004) 1.47
Controlled ultrasound-induced blood-brain barrier disruption using passive acoustic emissions monitoring. PLoS One (2012) 1.46
Progress and problems in the application of focused ultrasound for blood-brain barrier disruption. Ultrasonics (2008) 1.42
Clinical evaluation of the lateral sagittal infraclavicular block developed by MRI studies. Reg Anesth Pain Med (2005) 1.41
Uterine leiomyomas: MR imaging-guided focused ultrasound surgery--imaging predictors of success. Radiology (2008) 1.37
The impact of standing wave effects on transcranial focused ultrasound disruption of the blood-brain barrier in a rat model. Phys Med Biol (2010) 1.37
An MRI-compatible system for focused ultrasound experiments in small animal models. Med Phys (2009) 1.36
Targeted delivery of neural stem cells to the brain using MRI-guided focused ultrasound to disrupt the blood-brain barrier. PLoS One (2011) 1.35
Improved anti-tumor effect of liposomal doxorubicin after targeted blood-brain barrier disruption by MRI-guided focused ultrasound in rat glioma. Ultrasound Med Biol (2012) 1.29
A numerical study of transcranial focused ultrasound beam propagation at low frequency. Phys Med Biol (2005) 1.27
The kinetics of blood brain barrier permeability and targeted doxorubicin delivery into brain induced by focused ultrasound. J Control Release (2012) 1.23
A novel method for the intracellular delivery of siRNA using microbubble-enhanced focused ultrasound. Biochem Biophys Res Commun (2005) 1.21
A magnetic resonance imaging-compatible, large-scale array for trans-skull ultrasound surgery and therapy. J Ultrasound Med (2005) 1.21
Amyloid-β plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound. Exp Neurol (2013) 1.19
Multi-frequency characterization of the speed of sound and attenuation coefficient for longitudinal transmission of freshly excised human skulls. Phys Med Biol (2010) 1.19
Cavitation threshold of microbubbles in gel tunnels by focused ultrasound. Ultrasound Med Biol (2007) 1.18
Ultrasound-mediated blood-brain/blood-tumor barrier disruption improves outcomes with trastuzumab in a breast cancer brain metastasis model. J Control Release (2012) 1.18
Key factors that affect sonoporation efficiency in in vitro settings: the importance of standing wave in sonoporation. Biochem Biophys Res Commun (2007) 1.18
Image-guided neurosurgery at Brigham and Women's Hospital. IEEE Eng Med Biol Mag (2006) 1.14
Localised drug release using MRI-controlled focused ultrasound hyperthermia. Int J Hyperthermia (2010) 1.14
Influence of exposure time and pressure amplitude on blood-brain-barrier opening using transcranial ultrasound exposures. ACS Chem Neurosci (2010) 1.13
Focused-ultrasound disruption of the blood-brain barrier using closely-timed short pulses: influence of sonication parameters and injection rate. Ultrasound Med Biol (2011) 1.13
Targeted delivery of self-complementary adeno-associated virus serotype 9 to the brain, using magnetic resonance imaging-guided focused ultrasound. Hum Gene Ther (2012) 1.12
Multiple treatments with liposomal doxorubicin and ultrasound-induced disruption of blood-tumor and blood-brain barriers improve outcomes in a rat glioma model. J Control Release (2013) 1.12
Micro-receiver guided transcranial beam steering. IEEE Trans Ultrason Ferroelectr Freq Control (2002) 1.11
Focused ultrasound delivers targeted immune cells to metastatic brain tumors. Cancer Res (2013) 1.10
Correlation of ultrasound phase with physical skull properties. Ultrasound Med Biol (2002) 1.10
In vitro characterization of perfluorocarbon droplets for focused ultrasound therapy. Phys Med Biol (2010) 1.09
In vitro and in vivo high-intensity focused ultrasound thrombolysis. Invest Radiol (2012) 1.08
Ultrasound insertion loss of rat parietal bone appears to be proportional to animal mass at submegahertz frequencies. Ultrasound Med Biol (2011) 1.05
Induction of apoptosis in vivo in the rabbit brain with focused ultrasound and Optison. Ultrasound Med Biol (2006) 1.05
Transcranial ultrasound focus reconstruction with phase and amplitude correction. IEEE Trans Ultrason Ferroelectr Freq Control (2005) 1.04
Two-photon fluorescence microscopy study of cerebrovascular dynamics in ultrasound-induced blood-brain barrier opening. J Cereb Blood Flow Metab (2011) 1.04
Bio-acoustic thermal lensing and nonlinear propagation in focused ultrasound surgery using large focal spots: a parametric study. Phys Med Biol (2002) 1.04
Focused ultrasound effects on nerve action potential in vitro. Ultrasound Med Biol (2009) 1.03
A unified model for the speed of sound in cranial bone based on genetic algorithm optimization. Phys Med Biol (2002) 1.02
In vivo monitoring of focused ultrasound surgery using local harmonic motion. Ultrasound Med Biol (2008) 1.02
Contrast agent kinetics in the rabbit brain during exposure to therapeutic ultrasound. Ultrasound Med Biol (2010) 1.02
High-intensity focused ultrasound (HIFU) for dissolution of clots in a rabbit model of embolic stroke. PLoS One (2012) 1.01
Evaluation of referenceless thermometry in MRI-guided focused ultrasound surgery of uterine fibroids. J Magn Reson Imaging (2008) 1.00
Patterns of thermal deposition in the skull during transcranial focused ultrasound surgery. IEEE Trans Biomed Eng (2004) 0.99
Investigation of standing-wave formation in a human skull for a clinical prototype of a large-aperture, transcranial MR-guided focused ultrasound (MRgFUS) phased array: an experimental and simulation study. IEEE Trans Biomed Eng (2011) 0.99
A super-resolution ultrasound method for brain vascular mapping. Med Phys (2013) 0.99
Feasibility of using lateral mode coupling method for a large scale ultrasound phased array for noninvasive transcranial therapy. IEEE Trans Biomed Eng (2009) 0.98
Apoptosis signals in lymphoblasts induced by focused ultrasound. FASEB J (2004) 0.98
Liposomes as carriers of amphiphilic gadolinium chelates: the effect of membrane composition on incorporation efficacy and in vitro relaxivity. Int J Pharm (2002) 0.98
Focused ultrasound-mediated bbb disruption is associated with an increase in activation of AKT: experimental study in rats. BMC Neurol (2010) 0.97
A PVDF receiver for ultrasound monitoring of transcranial focused ultrasound therapy. IEEE Trans Biomed Eng (2010) 0.97
Noninvasive thermal ablation of hepatocellular carcinoma by using magnetic resonance imaging-guided focused ultrasound. Gastroenterology (2004) 0.97
Temperature change near microbubbles within a capillary network during focused ultrasound. Phys Med Biol (2010) 0.97
MRI-based thermal dosimetry and diffusion-weighted imaging of MRI-guided focused ultrasound thermal ablation of uterine fibroids. J Magn Reson Imaging (2009) 0.96
Simulations and measurements of transcranial low-frequency ultrasound therapy: skull-base heating and effective area of treatment. Phys Med Biol (2011) 0.96