Published in Angew Chem Int Ed Engl on February 06, 2004
Dioxygen activation at mononuclear nonheme iron active sites: enzymes, models, and intermediates. Chem Rev (2004) 6.11
Crystallographic and spectroscopic characterization of a nonheme Fe(IV)-O complex. Science (2003) 3.40
The 2-His-1-carboxylate facial triad: a versatile platform for dioxygen activation by mononuclear non-heme iron(II) enzymes. J Biol Inorg Chem (2005) 2.82
Nonheme FeIVO complexes that can oxidize the C-H bonds of cyclohexane at room temperature. J Am Chem Soc (2004) 2.26
Crystallographic comparison of manganese- and iron-dependent homoprotocatechuate 2,3-dioxygenases. J Bacteriol (2004) 1.84
Million-fold activation of the [Fe(2)(micro-O)(2)] diamond core for C-H bond cleavage. Nat Chem (2010) 1.82
A synthetic precedent for the [FeIV2(mu-O)2] diamond core proposed for methane monooxygenase intermediate Q. Proc Natl Acad Sci U S A (2007) 1.76
Spectroscopic and quantum chemical studies on low-spin FeIV=O complexes: Fe-O bonding and its contributions to reactivity. J Am Chem Soc (2007) 1.74
Aqueous FeIV==O: spectroscopic identification and oxo-group exchange. Angew Chem Int Ed Engl (2005) 1.74
Axial ligand tuning of a nonheme iron(IV)-oxo unit for hydrogen atom abstraction. Proc Natl Acad Sci U S A (2007) 1.70
End-on and side-on peroxo derivatives of non-heme iron complexes with pentadentate ligands: models for putative intermediates in biological iron/dioxygen chemistry. Inorg Chem (2003) 1.70
Chemical and spectroscopic evidence for an FeV-oxo complex. Science (2006) 1.64
Two-state reactivity in alkane hydroxylation by non-heme iron-oxo complexes. J Am Chem Soc (2006) 1.63
Structures of nonheme oxoiron(IV) complexes from X-ray crystallography, NMR spectroscopy, and DFT calculations. Angew Chem Int Ed Engl (2005) 1.62
A synthetic high-spin oxoiron(IV) complex: generation, spectroscopic characterization, and reactivity. Angew Chem Int Ed Engl (2009) 1.59
Human deoxyhypusine hydroxylase, an enzyme involved in regulating cell growth, activates O2 with a nonheme diiron center. Proc Natl Acad Sci U S A (2009) 1.52
Shape-selective interception by hydrocarbons of the O2-derived oxidant of a biomimetic nonheme iron complex. Angew Chem Int Ed Engl (2009) 1.48
Swapping metals in Fe- and Mn-dependent dioxygenases: evidence for oxygen activation without a change in metal redox state. Proc Natl Acad Sci U S A (2008) 1.47
High-valent nonheme iron-oxo species in biomimetic oxidations. J Inorg Biochem (2006) 1.46
A thiolate-ligated nonheme oxoiron(IV) complex relevant to cytochrome P450. Science (2005) 1.45
Structural insights into nonheme alkylperoxoiron(III) and oxoiron(IV) intermediates by X-ray absorption spectroscopy. J Am Chem Soc (2004) 1.45
An FeIV=O complex of a tetradentate tripodal nonheme ligand. Proc Natl Acad Sci U S A (2003) 1.44
Intermediates in the oxygenation of a nonheme diiron(II) complex, including the first evidence for a bound superoxo species. Proc Natl Acad Sci U S A (2005) 1.43
O2- and alpha-ketoglutarate-dependent tyrosyl radical formation in TauD, an alpha-keto acid-dependent non-heme iron dioxygenase. Biochemistry (2003) 1.41
Spectroscopic and quantum chemical characterization of the electronic structure and bonding in a non-heme FeIV[double bond]O complex. J Am Chem Soc (2004) 1.35
Proton- and reductant-assisted dioxygen activation by a nonheme iron(II) complex to form an oxoiron(IV) intermediate. Angew Chem Int Ed Engl (2008) 1.33
Axial ligand effects on the geometric and electronic structures of nonheme oxoiron(IV) complexes. J Am Chem Soc (2008) 1.32
The crystal structure of a high-spin oxoiron(IV) complex and characterization of its self-decay pathway. J Am Chem Soc (2010) 1.30
High-valent nonheme iron. Two distinct iron(IV) species derived from a common iron(II) precursor. J Am Chem Soc (2005) 1.29
A diiron(IV) complex that cleaves strong C-H and O-H bonds. Nat Chem (2009) 1.26
Oxygen activation by nonheme iron(II) complexes: alpha-keto carboxylate versus carboxylate. J Am Chem Soc (2003) 1.25
Olefin cis-dihydroxylation versus epoxidation by non-heme iron catalysts: two faces of an Fe(III)-OOH coin. J Am Chem Soc (2002) 1.24
Electronic structure and reactivity of low-spin Fe(III)-hydroperoxo complexes: comparison to activated bleomycin. J Am Chem Soc (2002) 1.21
(TAML)FeIV O complex in aqueous solution: synthesis and spectroscopic and computational characterization. Inorg Chem (2008) 1.19
A two-state reactivity rationale for counterintuitive axial ligand effects on the C-H activation reactivity of nonheme FeIV=O oxidants. Chemistry (2008) 1.14
Theoretical investigation of C--H hydroxylation by (N4Py)Fe(IV)=O(2+): an oxidant more powerful than P450? J Am Chem Soc (2005) 1.14
Electron paramagnetic resonance detection of intermediates in the enzymatic cycle of an extradiol dioxygenase. J Am Chem Soc (2008) 1.12
Axial ligand substituted nonheme FeIV=O complexes: observation of near-UV LMCT bands and Fe=O Raman vibrations. J Am Chem Soc (2005) 1.11
A combined NRVS and DFT study of Fe(IV)=O model complexes: a diagnostic method for the elucidation of non-heme iron enzyme intermediates. Angew Chem Int Ed Engl (2008) 1.10
Characterization of a high-spin non-heme Fe(III)-OOH intermediate and its quantitative conversion to an Fe(IV)═O complex. J Am Chem Soc (2011) 1.08
Mechanistic studies of 1-aminocyclopropane-1-carboxylic acid oxidase: single turnover reaction. J Biol Inorg Chem (2004) 1.07
The fundamental role of exchange-enhanced reactivity in C-H activation by S=2 oxo iron(IV) complexes. Angew Chem Int Ed Engl (2010) 1.06
A hyperactive cobalt-substituted extradiol-cleaving catechol dioxygenase. J Biol Inorg Chem (2010) 1.06
Nonheme oxoiron(IV) complexes of tris(2-pyridylmethyl)amine with cis-monoanionic ligands. Inorg Chem (2006) 1.04
Alkane hydroxylation by a nonheme iron catalyst that challenges the heme paradigm for oxygenase action. J Am Chem Soc (2007) 1.04
Iron Chemistry of a Pentadentate Ligand That Generates a Metastable Fe(III)-OOH Intermediate. Inorg Chem (1999) 1.04
electrochemical generation of a nonheme oxoiron(IV) complex. Inorg Chem (2006) 1.04
Redox potential and C-H bond cleaving properties of a nonheme Fe(IV)=O complex in aqueous solution. J Am Chem Soc (2010) 1.04
Dioxygen binding to complexes with Fe(II)2(mu-OH)2 cores: steric control of activation barriers and O2-adduct formation. Inorg Chem (2005) 1.03
Substrate-triggered activation of a synthetic [Fe2(μ-O)2] diamond core for C-H bond cleavage. J Am Chem Soc (2011) 1.00
Oxygenase activity in the self-hydroxylation of (s)-2-hydroxypropylphosphonic acid epoxidase involved in fosfomycin biosynthesis. J Am Chem Soc (2004) 1.00
Intramolecular aromatic amination through iron-mediated nitrene transfer. Angew Chem Int Ed Engl (2003) 0.99
The role of histidine 200 in MndD, the Mn(II)-dependent 3,4-dihydroxyphenylacetate 2,3-dioxygenase from Arthrobacter globiformis CM-2, a site-directed mutagenesis study. J Biol Inorg Chem (2005) 0.99
Sc3+-triggered oxoiron(IV) formation from O2 and its non-heme iron(II) precursor via a Sc3+-peroxo-Fe3+ intermediate. J Am Chem Soc (2013) 0.99
π-Frontier molecular orbitals in S = 2 ferryl species and elucidation of their contributions to reactivity. Proc Natl Acad Sci U S A (2012) 0.99
Nuclear resonance vibrational spectroscopy on the Fe(IV)=O S=2 non-heme site in TMG3tren: experimentally calibrated insights into reactivity. Angew Chem Int Ed Engl (2011) 0.99
Prediction of high-valent iron K-edge absorption spectra by time-dependent density functional theory. Dalton Trans (2011) 0.99
A two-state reactivity model explains unusual kinetic isotope effect patterns in C-H bond cleavage by nonheme oxoiron(IV) complexes. Angew Chem Int Ed Engl (2009) 0.98
Role of carboxylate bridges in modulating nonheme diiron(II)/O(2) reactivity. Inorg Chem (2003) 0.98
Spectroscopic study of [Fe2O2(5-Et3-TPA)2]3+: nature of the Fe2O2 diamond core and its possible relevance to high-valent binuclear non-heme enzyme intermediates. J Am Chem Soc (2003) 0.97
Olefin-dependent discrimination between two nonheme HO-FeV=O tautomeric species in catalytic H2O2 epoxidations. Chemistry (2009) 0.97
Spectroscopic studies of 1-aminocyclopropane-1-carboxylic acid oxidase: molecular mechanism and CO(2) activation in the biosynthesis of ethylene. J Am Chem Soc (2002) 0.96
Nonheme Oxoiron(IV) Complexes of Pentadentate N5 Ligands: Spectroscopy, Electrochemistry, and Oxidative Reactivity. Chem Sci (2013) 0.96
Spectroscopic and computational studies of (mu-oxo)(mu-1,2-peroxo)diiron(III) complexes of relevance to nonheme diiron oxygenase intermediates. J Phys Chem A (2008) 0.96
Biomimetic aryl hydroxylation derived from alkyl hydroperoxide at a nonheme iron center. Evidence for an Fe(IV)=O oxidant. J Am Chem Soc (2003) 0.96
ENDOR studies of the ligation and structure of the non-heme iron site in ACC oxidase. J Am Chem Soc (2005) 0.95
Formation of an aqueous oxoiron(IV) complex at pH 2-6 from a nonheme iron(II) complex and H2O2. Angew Chem Int Ed Engl (2006) 0.95
Determination by high-frequency and -field EPR of zero-field splitting in iron(IV) oxo complexes: implications for intermediates in nonheme iron enzymes. Inorg Chem (2008) 0.95
A more reactive trigonal-bipyramidal high-spin oxoiron(IV) complex with a cis-labile site. J Am Chem Soc (2011) 0.95
A tosylimido analogue of a nonheme oxoiron(IV) complex. Angew Chem Int Ed Engl (2006) 0.94
Mössbauer, electron paramagnetic resonance, and density functional theory studies of synthetic S = 1/2 Fe(III)-O-Fe(IV)═O complexes. Superexchange-mediated spin transition at the Fe(IV)═O site. Inorg Chem (2010) 0.94
Self-hydroxylation of taurine/alpha-ketoglutarate dioxygenase: evidence for more than one oxygen activation mechanism. J Biol Inorg Chem (2005) 0.94
Vibrational spectroscopy and analysis of pseudo-tetrahedral complexes with metal imido bonds. Inorg Chem (2006) 0.93
Structural "snapshots" along reaction pathways of non-heme iron enzymes. Angew Chem Int Ed Engl (2007) 0.93
Two faces of a biomimetic non-heme HO-Fe(v)=O oxidant: olefin epoxidation versus cis-dihydroxylation. Angew Chem Int Ed Engl (2005) 0.92
Tyrosinase-like reactivity in a Cu(III)2(mu-O)2 species. Chemistry (2008) 0.92
Direct evidence for oxygen-atom exchange between nonheme oxoiron(IV) complexes and isotopically labeled water. Angew Chem Int Ed Engl (2004) 0.92
X-ray absorption spectroscopic studies of high-spin nonheme (alkylperoxo)iron(III) intermediates. Inorg Chem (2007) 0.92
O2 activation and selective phenolate ortho hydroxylation by an unsymmetric dicopper mu-eta1:eta1-peroxido complex. Angew Chem Int Ed Engl (2010) 0.92
Modeling the cis-oxo-labile binding site motif of non-heme iron oxygenases: water exchange and oxidation reactivity of a non-heme iron(IV)-oxo compound bearing a tripodal tetradentate ligand. Chemistry (2011) 0.91
Near-stoichiometric conversion of H(2)O(2) to Fe(IV)=O at a nonheme iron(II) center. Insights into the O-O bond cleavage step. J Am Chem Soc (2010) 0.91
4-nitrocatechol as a probe of a Mn(II)-dependent extradiol-cleaving catechol dioxygenase (MndD): comparison with relevant Fe(II) and Mn(II) model complexes. J Biol Inorg Chem (2002) 0.90
Iron-catalyzed olefin epoxidation in the presence of acetic acid: insights into the nature of the metal-based oxidant. J Am Chem Soc (2007) 0.90
Interconversion of two oxidized forms of taurine/alpha-ketoglutarate dioxygenase, a non-heme iron hydroxylase: evidence for bicarbonate binding. Proc Natl Acad Sci U S A (2003) 0.90
Self-hydroxylation of perbenzoic acids at a nonheme iron(II) center. Chem Commun (Camb) (2005) 0.90
Oxygen activation at mononuclear nonheme iron centers: a superoxo perspective. Inorg Chem (2010) 0.90
A density functional study of O-O bond cleavage for a biomimetic non-heme iron complex demonstrating an Fe(v)-intermediate. J Am Chem Soc (2002) 0.89
An unusual peroxo intermediate of the arylamine oxygenase of the chloramphenicol biosynthetic pathway. J Am Chem Soc (2015) 0.88
Iron-catalyzed asymmetric olefin cis-dihydroxylation with 97% enantiomeric excess. Angew Chem Int Ed Engl (2008) 0.88
Axial coordination of carboxylate activates the non-heme FeIV=O unit. Angew Chem Int Ed Engl (2005) 0.88
Iron Coordination Chemistry of Phenylpyruvate: An Unexpected kappa3-bridging mode that leads to oxidative cleavage of the C2-C3 bond. Inorg Chem (2005) 0.88
Reversible formation of iodosylbenzene-iron porphyrin intermediates in the reaction of oxoiron(IV) porphyrin pi-cation radicals and iodobenzene. Angew Chem Int Ed Engl (2003) 0.88
Copper corroles are inherently saddled. Inorg Chem (2009) 0.87
Unusual peroxo intermediates in the reaction of dioxygen with carboxylate-bridged diiron(II,II) paddlewheel complexes. Angew Chem Int Ed Engl (2002) 0.87
Mössbauer and DFT study of the ferromagnetically coupled diiron(IV) precursor to a complex with an Fe(IV)(2)O(2) diamond core. J Am Chem Soc (2009) 0.87
One-electron oxidation of an oxoiron(IV) complex to form an [O═FeV═NR]+ center. Proc Natl Acad Sci U S A (2012) 0.87
Spin-state rationale for the peroxo-stabilizing role of the thiolate ligand in superoxide reductase. Angew Chem Int Ed Engl (2005) 0.87
Observed enhancement of the reactivity of a biomimetic diiron complex by the addition of water - mechanistic insights from theoretical modeling. Dalton Trans (2009) 0.87
A Mononuclear Carboxylate-Rich Oxoiron(IV) Complex: a Structural and Functional Mimic of TauD Intermediate 'J' Chem Sci (2012) 0.87