PubRank

Kazuhito Tomizawa

Author PubWeight™ 72.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cdk5-dependent regulation of glucose-stimulated insulin secretion. Nat Med 2005 4.31
2 CaM kinase I alpha-induced phosphorylation of Drp1 regulates mitochondrial morphology. J Cell Biol 2008 2.62
3 Ciliary transition zone activation of phosphorylated Tctex-1 controls ciliary resorption, S-phase entry and fate of neural progenitors. Nat Cell Biol 2011 2.06
4 A new cell-permeable peptide allows successful allogeneic islet transplantation in mice. Nat Med 2004 2.01
5 Deficit of tRNA(Lys) modification by Cdkal1 causes the development of type 2 diabetes in mice. J Clin Invest 2011 1.80
6 Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain. J Biol Chem 2005 1.64
7 Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1. J Biol Chem 2005 1.57
8 Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration. J Biol Chem 2003 1.55
9 Identification of eukaryotic and prokaryotic methylthiotransferase for biosynthesis of 2-methylthio-N6-threonylcarbamoyladenosine in tRNA. J Biol Chem 2010 1.47
10 Regulation of N-methyl-D-aspartate receptors by calpain in cortical neurons. J Biol Chem 2005 1.21
11 Control of cyclin-dependent kinase 5 (Cdk5) activity by glutamatergic regulation of p35 stability. J Neurochem 2005 1.20
12 The NH2 terminus of influenza virus hemagglutinin-2 subunit peptides enhances the antitumor potency of polyarginine-mediated p53 protein transduction. J Biol Chem 2004 1.19
13 Impairment of hippocampal long-term depression and defective spatial learning and memory in p35 mice. J Neurochem 2005 1.09
14 Development of p53 protein transduction therapy using membrane-permeable peptides and the application to oral cancer cells. Mol Cancer Ther 2002 1.00
15 Development of bionanocapsules targeting brain tumors. J Control Release 2007 1.00
16 Regulation of synaptic vesicle recycling by calcineurin in different vesicle pools. Neurosci Res 2005 0.96
17 Functional loss of Cdkal1, a novel tRNA modification enzyme, causes the development of type 2 diabetes. Endocr J 2011 0.96
18 Truncations of amphiphysin I by calpain inhibit vesicle endocytosis during neural hyperexcitation. EMBO J 2007 0.95
19 HIV-1 Tat inhibits long-term potentiation and attenuates spatial learning [corrected]. Ann Neurol 2004 0.94
20 Photo-acceleration of protein release from endosome in the protein transduction system. FEBS Lett 2004 0.94
21 Calpain-calcineurin signaling in the pathogenesis of calcium-dependent disorder. Acta Med Okayama 2007 0.93
22 Amphiphysin I and regulation of synaptic vesicle endocytosis. Acta Med Okayama 2009 0.92
23 Protein Therapy: in vivo protein transduction by polyarginine (11R) PTD and subcellular targeting delivery. Curr Protein Pept Sci 2003 0.91
24 Enhanced intracellular delivery using arginine-rich peptides by the addition of penetration accelerating sequences (Pas). J Control Release 2009 0.91
25 Inhibition of excitatory neuronal cell death by cell-permeable calcineurin autoinhibitory peptide. J Neurochem 2003 0.90
26 Amphiphysin 1 is important for actin polymerization during phagocytosis. Mol Biol Cell 2007 0.89
27 Calcineurin plays different roles in group II metabotropic glutamate receptor- and NMDA receptor-dependent long-term depression. J Neurosci 2002 0.89
28 Cyclin-dependent kinase 5 (Cdk5): a potential therapeutic target for the treatment of neurodegenerative diseases and diabetes mellitus. Mini Rev Med Chem 2007 0.89
29 Stabilization of actin bundles by a dynamin 1/cortactin ring complex is necessary for growth cone filopodia. J Neurosci 2013 0.89
30 Regulation of mitochondrial dynamics and neurodegenerative diseases. Acta Med Okayama 2011 0.87
31 Calpain inhibitors prevent neuronal cell death and ameliorate motor disturbances after compression-induced spinal cord injury in rats. J Neurotrauma 2005 0.86
32 Development of a bifunctional immunoliposome system for combined drug delivery and imaging in vivo. Biomaterials 2010 0.86
33 Oxytocin: a therapeutic target for mental disorders. J Physiol Sci 2012 0.85
34 High oxygen condition facilitates the differentiation of mouse and human pluripotent stem cells into pancreatic progenitors and insulin-producing cells. J Biol Chem 2014 0.84
35 A cell-permeable NFAT inhibitor peptide prevents pressure-overload cardiac hypertrophy. Chem Biol Drug Des 2006 0.84
36 A Cdk5 inhibitor enhances the induction of insulin secretion by exendin-4 both in vitro and in vivo. J Physiol Sci 2007 0.84
37 A CACNB4 mutation shows that altered Ca(v)2.1 function may be a genetic modifier of severe myoclonic epilepsy in infancy. Neurobiol Dis 2008 0.84
38 p53 protein transduction therapy: successful targeting and inhibition of the growth of the bladder cancer cells. Eur Urol 2005 0.84
39 Delivery of sodium borocaptate to glioma cells using immunoliposome conjugated with anti-EGFR antibodies by ZZ-His. Biomaterials 2009 0.83
40 Critical differences in magnitude and duration of N-methyl D-aspartate(NMDA) receptor activation between long-term potentiation (LTP) and long-term depression (LTD) induction. Acta Med Okayama 2008 0.83
41 A protein transduction method using oligo-arginine (3R) for the delivery of transcription factors into cell nuclei. Biomaterials 2012 0.83
42 Ubiquitination-resistant p53 protein transduction therapy facilitates anti-cancer effect on the growth of human malignant glioma cells. FEBS Lett 2005 0.83
43 Involvement of calcineurin in glutamate-induced mitochondrial dynamics in neurons. Neurosci Res 2007 0.83
44 Expression of a constitutively active calcineurin encoded by an intron-retaining mRNA in follicular keratinocytes. PLoS One 2011 0.82
45 Protein transduction into the mouse otocyst using arginine-rich cell-penetrating peptides. Neuroreport 2011 0.82
46 Effects of purified newly developed botulinum neurotoxin type A in rat prostate. Urology 2009 0.82
47 Transformation of eEF1Bδ into heat-shock response transcription factor by alternative splicing. EMBO Rep 2011 0.81
48 Calcineurin mediates bladder smooth muscle hypertrophy after bladder outlet obstruction. J Urol 2003 0.81
49 [Protein transduction by poly-arginine]. Nihon Yakurigaku Zasshi 2003 0.81
50 Protein therapy using heme-oxygenase-1 fused to a polyarginine transduction domain attenuates cerebral vasospasm after experimental subarachnoid hemorrhage. J Cereb Blood Flow Metab 2011 0.81
51 Anks4b, a novel target of HNF4α protein, interacts with GRP78 protein and regulates endoplasmic reticulum stress-induced apoptosis in pancreatic β-cells. J Biol Chem 2012 0.80
52 Quantitative PCR measurement of tRNA 2-methylthio modification for assessing type 2 diabetes risk. Clin Chem 2013 0.80
53 Role of the hippocampal CA2 region following postischemic hypothermia in gerbil. Brain Res Mol Brain Res 2003 0.80
54 Poly-arginine-fused calpastatin peptide, a living cell membrane-permeable and specific inhibitor for calpain. Neurosci Res 2003 0.80
55 RGS2 mediates the anxiolytic effect of oxytocin. Brain Res 2012 0.80
56 Protein transduction method for cerebrovascular disorders. Acta Med Okayama 2009 0.80
57 Generation of functional insulin-producing cells from mouse embryonic stem cells through 804G cell-derived extracellular matrix and protein transduction of transcription factors. Stem Cells Transl Med 2013 0.80
58 Inhibitory effect of polyunsaturated fatty acids on apoptosis induced by etoposide, okadaic acid and AraC in Neuro2a cells. Acta Med Okayama 2007 0.79
59 Major Cdk5-dependent phosphorylation sites of amphiphysin 1 are implicated in the regulation of the membrane binding and endocytosis. J Neurochem 2007 0.79
60 Induction of autophagic cell death of glioma-initiating cells by cell-penetrating D-isomer peptides consisting of Pas and the p53 C-terminus. Biomaterials 2012 0.79
61 Ca(2+)-independent syntaxin binding to the C(2)B effector region of synaptotagmin. Mol Cell Neurosci 2011 0.79
62 Oxytocin mediates the antidepressant effects of mating behavior in male mice. Neurosci Res 2010 0.79
63 Inhibition of H3K18 deacetylation of Sirt7 by Myb-binding protein 1a (Mybbp1a). Biochem Biophys Res Commun 2013 0.79
64 A cautionary tale: the non-causal association between type 2 diabetes risk SNP, rs7756992, and levels of non-coding RNA, CDKAL1-v1. Diabetologia 2015 0.79
65 2-methoxyestradiol enhances p53 protein transduction therapy-associated inhibition of the proliferation of oral cancer cells through the suppression of NFkappaB activity. Acta Med Okayama 2004 0.78
66 Novel protein transduction method by using 11R: an effective new drug delivery system for the treatment of cerebrovascular diseases. Stroke 2007 0.78
67 Cell-penetrating D-isomer peptides of p53 C-terminus: long-term inhibitory effect on the growth of bladder cancer. Urology 2009 0.77
68 Exposure of mouse to high gravitation forces induces long-term potentiation in the hippocampus. Acta Med Okayama 2004 0.77
69 A new approach to inhibiting astrocytic IP3-induced intracellular calcium increase in an astrocyte-neuron co-culture system. Brain Res 2005 0.77
70 Theranostic protein targeting ErbB2 for bioluminescence imaging and therapy for cancer. PLoS One 2013 0.77
71 Cyclin G2 promotes hypoxia-driven local invasion of glioblastoma by orchestrating cytoskeletal dynamics. Neoplasia 2013 0.77
72 Combining poly-arginine with the hydrophobic counter-anion 4-(1-pyrenyl)-butyric acid for protein transduction in transdermal delivery. Biomaterials 2012 0.77
73 [Physiological function of cyclin-dependent kinase 5 in neuron]. Seikagaku 2005 0.75
74 Colocalization of oxytocin and phosphorylated form of elongation factor 2 in the rat hypothalamus. Acta Med Okayama 2007 0.75
75 [Molecular basis of tRNA methylthiolation and the pathological implications]. Seikagaku 2016 0.75