Published in Structure on February 01, 2004
A contemporary view of coronavirus transcription. J Virol (2006) 2.47
Ultrastructure and origin of membrane vesicles associated with the severe acute respiratory syndrome coronavirus replication complex. J Virol (2006) 2.20
Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection. Clin Microbiol Rev (2007) 1.68
The severe acute respiratory syndrome coronavirus Nsp15 protein is an endoribonuclease that prefers manganese as a cofactor. J Virol (2004) 1.67
SARS-coronavirus replication/transcription complexes are membrane-protected and need a host factor for activity in vitro. PLoS Pathog (2008) 1.59
Functional and genetic analysis of coronavirus replicase-transcriptase proteins. PLoS Pathog (2005) 1.52
Viral proteomics. Microbiol Mol Biol Rev (2007) 1.43
Analysis of intraviral protein-protein interactions of the SARS coronavirus ORFeome. PLoS One (2007) 1.42
The structure of a rigorously conserved RNA element within the SARS virus genome. PLoS Biol (2004) 1.35
Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family. Proc Natl Acad Sci U S A (2006) 1.33
Novel beta-barrel fold in the nuclear magnetic resonance structure of the replicase nonstructural protein 1 from the severe acute respiratory syndrome coronavirus. J Virol (2007) 1.30
Crystal structure of nonstructural protein 10 from the severe acute respiratory syndrome coronavirus reveals a novel fold with two zinc-binding motifs. J Virol (2006) 1.24
Topology and membrane anchoring of the coronavirus replication complex: not all hydrophobic domains of nsp3 and nsp6 are membrane spanning. J Virol (2008) 1.23
Processing of open reading frame 1a replicase proteins nsp7 to nsp10 in murine hepatitis virus strain A59 replication. J Virol (2007) 1.22
RNA-RNA and RNA-protein interactions in coronavirus replication and transcription. RNA Biol (2011) 1.21
Dodecamer structure of severe acute respiratory syndrome coronavirus nonstructural protein nsp10. J Virol (2006) 1.19
Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro. J Virol (2005) 1.15
Human coronavirus 229E papain-like proteases have overlapping specificities but distinct functions in viral replication. J Virol (2007) 1.12
New antiviral target revealed by the hexameric structure of mouse hepatitis virus nonstructural protein nsp15. J Virol (2006) 1.11
Genetic interactions between an essential 3' cis-acting RNA pseudoknot, replicase gene products, and the extreme 3' end of the mouse coronavirus genome. J Virol (2007) 1.09
Molecular determinants of severe acute respiratory syndrome coronavirus pathogenesis and virulence in young and aged mouse models of human disease. J Virol (2011) 1.07
Dynamics of coronavirus replication-transcription complexes. J Virol (2009) 1.07
Murine hepatitis virus replicase protein nsp10 is a critical regulator of viral RNA synthesis. J Virol (2007) 1.06
Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex. PLoS Pathog (2011) 1.05
Characterization of White bream virus reveals a novel genetic cluster of nidoviruses. J Virol (2006) 1.00
Severe acute respiratory syndrome coronavirus nsp9 dimerization is essential for efficient viral growth. J Virol (2009) 0.89
Functional and genetic studies of the substrate specificity of coronavirus infectious bronchitis virus 3C-like proteinase. J Virol (2010) 0.86
Expression, purification and crystallization of a lyssavirus matrix (M) protein. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.86
A new cistron in the murine hepatitis virus replicase gene. J Virol (2010) 0.84
Biogenesis and dynamics of the coronavirus replicative structures. Viruses (2012) 0.84
SARS coronavirus replicase proteins in pathogenesis. Virus Res (2007) 0.83
Nonstructural proteins 7 and 8 of feline coronavirus form a 2:1 heterotrimer that exhibits primer-independent RNA polymerase activity. J Virol (2012) 0.81
Crystallization and preliminary X-ray diffraction analysis of Nsp15 from SARS coronavirus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.79
Crystallization and preliminary X-ray diffraction studies of infectious bronchitis virus nonstructural protein 9. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.77
International research networks in viral structural proteomics: again, lessons from SARS. Antiviral Res (2007) 0.76
Structural basis for dimerization and RNA binding of avian infectious bronchitis virus nsp9. Protein Sci (2017) 0.75
Expression, crystallization and preliminary crystallographic study of the functional mutant (N60K) of nonstructural protein 9 from Human coronavirus HKU1. Acta Crystallogr F Struct Biol Commun (2014) 0.75
Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia. J Virol (2005) 9.13
Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage. J Mol Biol (2003) 9.09
Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells. PLoS One (2008) 6.98
Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1. J Virol (2006) 6.30
A highly conserved neutralizing epitope on group 2 influenza A viruses. Science (2011) 5.66
Three Indonesian clusters of H5N1 virus infection in 2005. N Engl J Med (2006) 5.14
Lung pathology of fatal severe acute respiratory syndrome. Lancet (2003) 5.02
Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group. J Virol (2013) 4.98
Senescence impairs successful reprogramming to pluripotent stem cells. Genes Dev (2009) 4.69
Ultrasonic locating devices for central venous cannulation: meta-analysis. BMJ (2003) 4.58
Dating the emergence of pandemic influenza viruses. Proc Natl Acad Sci U S A (2009) 4.36
Emergence of a novel swine-origin influenza A virus (S-OIV) H1N1 virus in humans. J Clin Virol (2009) 4.10
Protein production and purification. Nat Methods (2008) 3.97
Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL. Nature (2002) 3.78
A procedure for setting up high-throughput nanolitre crystallization experiments. Crystallization workflow for initial screening, automated storage, imaging and optimization. Acta Crystallogr D Biol Crystallogr (2005) 3.75
MERS coronaviruses in dromedary camels, Egypt. Emerg Infect Dis (2014) 3.64
The genesis and source of the H7N9 influenza viruses causing human infections in China. Nature (2013) 3.60
Highly conserved protective epitopes on influenza B viruses. Science (2012) 3.47
A versatile ligation-independent cloning method suitable for high-throughput expression screening applications. Nucleic Acids Res (2007) 3.22
A structural basis for immunodominant human T cell receptor recognition. Nat Immunol (2003) 3.15
Lysine methylation as a routine rescue strategy for protein crystallization. Structure (2006) 3.14
Towards rationalization of crystallization screening for small- to medium-sized academic laboratories: the PACT/JCSG+ strategy. Acta Crystallogr D Biol Crystallogr (2005) 3.13
What does structure tell us about virus evolution? Curr Opin Struct Biol (2005) 3.02
Long-term differences in language and cognitive function after childhood exposure to anesthesia. Pediatrics (2012) 2.98
Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection. Nat Genet (2005) 2.82
A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat Struct Mol Biol (2012) 2.81
Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2. Nat Struct Mol Biol (2008) 2.58
MERS coronavirus in dromedary camel herd, Saudi Arabia. Emerg Infect Dis (2014) 2.47
Insights into assembly from structural analysis of bacteriophage PRD1. Nature (2004) 2.47
Crystal structure of a soluble CD28-Fab complex. Nat Immunol (2005) 2.46
The interaction properties of costimulatory molecules revisited. Immunity (2002) 2.43
A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting. Nature (2006) 2.41
Bluetongue virus VP4 is an RNA-capping assembly line. Nat Struct Mol Biol (2007) 2.40
Glycoprotein structural genomics: solving the glycosylation problem. Structure (2007) 2.40
Long-term evolution and transmission dynamics of swine influenza A virus. Nature (2011) 2.39
Dengue virus inhibits alpha interferon signaling by reducing STAT2 expression. J Virol (2005) 2.37
A functional and structural basis for TCR cross-reactivity in multiple sclerosis. Nat Immunol (2002) 2.31
Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity. EMBO J (2011) 2.22
Stability of the Larsen B ice shelf on the Antarctic Peninsula during the Holocene epoch. Nature (2005) 2.20
Structure of the DNA repair helicase XPD. Cell (2008) 2.16
Detection of a fourth orbivirus non-structural protein. PLoS One (2011) 2.11
The postfusion structure of baculovirus gp64 supports a unified view of viral fusion machines. Nat Struct Mol Biol (2008) 2.09
Hemagglutinin-neuraminidase balance confers respiratory-droplet transmissibility of the pandemic H1N1 influenza virus in ferrets. Proc Natl Acad Sci U S A (2011) 2.04
West Nile virus core protein; tetramer structure and ribbon formation. Structure (2004) 2.04
Structure of the integrin binding fragment from fibrillin-1 gives new insights into microfibril organization. Structure (2004) 1.97
The structure of an RNAi polymerase links RNA silencing and transcription. PLoS Biol (2006) 1.96
In situ macromolecular crystallography using microbeams. Acta Crystallogr D Biol Crystallogr (2012) 1.94
Structure and functionality in flavivirus NS-proteins: perspectives for drug design. Antiviral Res (2009) 1.87
Insights into the evolution of a complex virus from the crystal structure of vaccinia virus D13. Structure (2011) 1.86
Atomic snapshots of an RNA packaging motor reveal conformational changes linking ATP hydrolysis to RNA translocation. Cell (2004) 1.86
Dengue virus NS5 inhibits interferon-alpha signaling by blocking signal transducer and activator of transcription 2 phosphorylation. J Infect Dis (2009) 1.83
Structural basis of YAP recognition by TEAD4 in the hippo pathway. Genes Dev (2010) 1.80
Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis. J Virol (2005) 1.76
Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein. J Gen Virol (2007) 1.73
Avian coronavirus in wild aquatic birds. J Virol (2011) 1.73
Tropism of and innate immune responses to the novel human betacoronavirus lineage C virus in human ex vivo respiratory organ cultures. J Virol (2013) 1.68
Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47. Mol Cell (2008) 1.68
The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D. Nat Struct Biol (2003) 1.68
Tropism and innate host responses of the 2009 pandemic H1N1 influenza virus in ex vivo and in vitro cultures of human conjunctiva and respiratory tract. Am J Pathol (2010) 1.67
Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK. J Immunol (2009) 1.66
An in-depth analysis of original antigenic sin in dengue virus infection. J Virol (2010) 1.63
Structure unifies the viral universe. Annu Rev Biochem (2012) 1.58
Picornavirus uncoating intermediate captured in atomic detail. Nat Commun (2013) 1.57
Vaccinia virus proteins A52 and B14 Share a Bcl-2-like fold but have evolved to inhibit NF-kappaB rather than apoptosis. PLoS Pathog (2008) 1.57
Membrane structure and interactions with protein and DNA in bacteriophage PRD1. Nature (2004) 1.53
Implications of the HIV-1 Rev dimer structure at 3.2 A resolution for multimeric binding to the Rev response element. Proc Natl Acad Sci U S A (2010) 1.51
T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides. Immunity (2009) 1.50
Isotonic versus hypotonic solutions for maintenance intravenous fluid administration in children. Cochrane Database Syst Rev (2014) 1.49
Evolution of viral structure. Theor Popul Biol (2002) 1.48
Detection of diverse astroviruses from bats in China. J Gen Virol (2009) 1.46
How baculovirus polyhedra fit square pegs into round holes to robustly package viruses. EMBO J (2009) 1.46
Hyperinduction of cyclooxygenase-2-mediated proinflammatory cascade: a mechanism for the pathogenesis of avian influenza H5N1 infection. J Infect Dis (2008) 1.46
The Protein Information Management System (PiMS): a generic tool for any structural biology research laboratory. Acta Crystallogr D Biol Crystallogr (2011) 1.45
Tetracycline-inducible packaging cell line for production of flavivirus replicon particles. J Virol (2004) 1.44
RNA polymerase I structure and transcription regulation. Nature (2013) 1.42
A primer for clinical researchers in the emergency department: Part II: research science and conduct. Emerg Med Australas (2010) 1.38
Insights into virus evolution and membrane biogenesis from the structure of the marine lipid-containing bacteriophage PM2. Mol Cell (2008) 1.37