Published in Toxicol Appl Pharmacol on February 15, 2004
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Instillation of six different ultrafine carbon particles indicates a surface area threshold dose for acute lung inflammation in mice. Environ Health Perspect (2006) 2.51
Immunosuppressive regulatory T cells are abundant in the reactive lymphocytes of Hodgkin lymphoma. Blood (2003) 2.47
4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2002) 2.38
Expression of adhesion molecules during apoptosis of circulating neutrophils in COPD. Chest (2004) 2.33
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The pro-inflammatory effects of low-toxicity low-solubility particles, nanoparticles and fine particles, on epithelial cells in vitro: the role of surface area. Occup Environ Med (2007) 2.29
Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10). Free Radic Biol Med (2003) 2.28
Oxidative stress and lipid mediators induced in alveolar macrophages by ultrafine particles. Free Radic Biol Med (2005) 2.12
Identification, immunomodulatory activity, and immunogenicity of the major helper T-cell epitope on the K blood group antigen. Blood (2012) 2.10
A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluation. COPD (2012) 2.07
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Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs. Am J Respir Cell Mol Biol (2004) 1.83
Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2013) 1.79
Oxidative stress and TNF-alpha induce histone acetylation and NF-kappaB/AP-1 activation in alveolar epithelial cells: potential mechanism in gene transcription in lung inflammation. Mol Cell Biochem (2002) 1.77
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Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis. Ann Am Thorac Soc (2015) 1.72
Genomewide linkage analysis identifies novel genetic Loci for lung function in mice. Am J Respir Crit Care Med (2005) 1.67
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Socioeconomic deprivation increases the effect of winter on admissions to hospital with COPD: retrospective analysis of 10 years of national hospitalisation data. Prim Care Respir J (2013) 1.60
Hazard and risk assessment of a nanoparticulate cerium oxide-based diesel fuel additive - a case study. Inhal Toxicol (2008) 1.60
Metal oxide nanoparticles induce unique inflammatory footprints in the lung: important implications for nanoparticle testing. Environ Health Perspect (2010) 1.57
Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease. Hum Mutat (2006) 1.53
Soluble transition metals cause the pro-inflammatory effects of welding fumes in vitro. Toxicol Appl Pharmacol (2004) 1.47
Graphene-based nanoplatelets: a new risk to the respiratory system as a consequence of their unusual aerodynamic properties. ACS Nano (2012) 1.46
Exposure to concentrated ambient particles does not affect vascular function in patients with coronary heart disease. Environ Health Perspect (2008) 1.45
Inbred strain variation in lung function. Mamm Genome (2002) 1.45
Mitigation of radon and thoron decay products by filtration. Sci Total Environ (2011) 1.43
Pulmonary function is associated with distal aortic calcium, not proximal aortic distensibility. MESA lung study. COPD (2011) 1.41
Histone acetylation regulates epithelial IL-8 release mediated by oxidative stress from environmental particles. Am J Physiol Lung Cell Mol Physiol (2002) 1.41
Cigarette smoke prevents apoptosis through inhibition of caspase activation and induces necrosis. Am J Respir Cell Mol Biol (2003) 1.35
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Lung function in idiopathic pulmonary fibrosis--extended analyses of the IFIGENIA trial. Respir Res (2009) 1.34
A dose-controlled system for air-liquid interface cell exposure and application to zinc oxide nanoparticles. Part Fibre Toxicol (2009) 1.34
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Deducing in vivo toxicity of combustion-derived nanoparticles from a cell-free oxidative potency assay and metabolic activation of organic compounds. Environ Health Perspect (2008) 1.32
Airway dimensions in COPD: relationships with clinical variables. Respir Med (2010) 1.30
Predicting outcomes from 6-minute walk distance in chronic obstructive pulmonary disease. J Am Med Dir Assoc (2011) 1.28
Increased platelet activation in patients with stable and acute exacerbation of COPD. Thorax (2011) 1.25
Role of oxidative stress in ultrafine particle-induced exacerbation of allergic lung inflammation. Am J Respir Crit Care Med (2009) 1.22
Cigarette smoke disrupts VEGF165-VEGFR-2 receptor signaling complex in rat lungs and patients with COPD: morphological impact of VEGFR-2 inhibition. Am J Physiol Lung Cell Mol Physiol (2005) 1.22
Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team. Am J Respir Crit Care Med (2014) 1.20
Potential role of IL-8, platelet-activating factor and TNF-alpha in the sequestration of neutrophils in the lung: effects on neutrophil deformability, adhesion receptor expression, and chemotaxis. Eur J Immunol (2002) 1.20
Particle traps prevent adverse vascular and prothrombotic effects of diesel engine exhaust inhalation in men. Circulation (2011) 1.19
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Oxidant generation by particulate matter: from biologically effective dose to a promising, novel metric. Occup Environ Med (2007) 1.14
Role of inflammation in cardiopulmonary health effects of PM. Toxicol Appl Pharmacol (2005) 1.12
Comparative toxicity of standard nickel and ultrafine nickel in lung after intratracheal instillation. J Occup Health (2003) 1.11
Effects of ultrafine carbon particle inhalation on allergic inflammation of the lung. J Allergy Clin Immunol (2006) 1.10
Nanoscience, nanotoxicology, and the need to think small. Lancet (2005) 1.10
Antioxidant pharmacological therapies for COPD. Curr Opin Pharmacol (2012) 1.10
Regulatory T cells secreting IL-10 dominate the immune response to EBV latent membrane protein 1. J Immunol (2003) 1.09
Association of MMP-2 polymorphisms with severe and very severe COPD: a case control study of MMPs-1, 9 and 12 in a European population. BMC Med Genet (2010) 1.08
Living and dying with severe chronic obstructive pulmonary disease: multi-perspective longitudinal qualitative study. BMJ Support Palliat Care (2011) 1.08
Local and systemic induction of CD4+CD25+ regulatory T-cell population by non-Hodgkin lymphoma. Blood (2008) 1.08
The impact of a telemetric chronic obstructive pulmonary disease monitoring service: randomised controlled trial with economic evaluation and nested qualitative study. Prim Care Respir J (2009) 1.07
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Mucociliary and long-term particle clearance in the airways of healthy nonsmoker subjects. J Appl Physiol (1985) (2004) 1.07
Metabolic profiling detects biomarkers of protein degradation in COPD patients. Eur Respir J (2011) 1.06
Clonal regulatory T cells specific for a red blood cell autoantigen in human autoimmune hemolytic anemia. Blood (2007) 1.05
Health effects of ambient particulate matter--biological mechanisms and inflammatory responses to in vitro and in vivo particle exposures. Inhal Toxicol (2008) 1.03
Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD. Mol Biosyst (2012) 1.02
Molecular mechanism of transforming growth factor (TGF)-beta1-induced glutathione depletion in alveolar epithelial cells. Involvement of AP-1/ARE and Fra-1. J Biol Chem (2002) 1.02
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Rh autoantigen presentation to helper T cells in chronic lymphocytic leukemia by malignant B cells. Blood (2004) 1.00