Published in J Immunol on March 01, 2004
B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance. Blood (2010) 3.21
Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family. Immunol Rev (2011) 2.54
Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells. Immunol Rev (2009) 2.00
Suppression of HIV-specific T cell activity by lymph node CD25+ regulatory T cells from HIV-infected individuals. Proc Natl Acad Sci U S A (2007) 1.82
Cytotoxic T lymphocyte antigen-4-dependent down-modulation of costimulatory molecules on dendritic cells in CD4+ CD25+ regulatory T-cell-mediated suppression. Immunology (2006) 1.79
Intestinal macrophages and response to microbial encroachment. Mucosal Immunol (2010) 1.76
CD4+CD25+ regulatory T cells restrain pathogenic responses during Leishmania amazonensis infection. J Immunol (2005) 1.46
Acquisition of suppressive function by activated human CD4+ CD25- T cells is associated with the expression of CTLA-4 not FoxP3. J Immunol (2008) 1.45
Human peripheral blood T regulatory cells (Tregs), functionally primed CCR4+ Tregs and unprimed CCR4- Tregs, regulate effector T cells using FasL. J Immunol (2007) 1.38
Repeated social defeat activates dendritic cells and enhances Toll-like receptor dependent cytokine secretion. Brain Behav Immun (2008) 1.30
Immunoregulation of dendritic cells. Clin Med Res (2005) 1.23
Inducing CTLA-4-dependent immune regulation by selective CD28 blockade promotes regulatory T cells in organ transplantation. Sci Transl Med (2010) 1.17
Optimization of dendritic cell loading with tumor cell lysates for cancer immunotherapy. J Immunother (2008) 1.16
Brain dendritic cells in ischemic stroke: time course, activation state, and origin. Brain Behav Immun (2009) 1.16
Exclusion of T Cells From Pancreatic Carcinomas in Mice Is Regulated by Ly6C(low) F4/80(+) Extratumoral Macrophages. Gastroenterology (2015) 1.12
Suppression of the immunologic response to peanut during immunotherapy is often transient. J Allergy Clin Immunol (2014) 1.07
Apoptotic cells induce dendritic cell-mediated suppression via interferon-gamma-induced IDO. Immunology (2007) 1.04
CTLA-4-Ig therapy diminishes the frequency but enhances the function of Treg cells in patients with rheumatoid arthritis. J Clin Immunol (2011) 1.02
Presence of suppressor HIV-specific CD8+ T cells is associated with increased PD-1 expression on effector CD8+ T cells. J Immunol (2008) 0.98
CTLA-4 promotes Foxp3 induction and regulatory T cell accumulation in the intestinal lamina propria. Mucosal Immunol (2012) 0.98
Type I IFN signaling in CD8- DCs impairs Th1-dependent malaria immunity. J Clin Invest (2014) 0.96
Targeting CD28, CTLA-4 and PD-L1 costimulation differentially controls immune synapses and function of human regulatory and conventional T-cells. PLoS One (2013) 0.92
Altered immunoregulation in rheumatoid arthritis: the role of regulatory T cells and proinflammatory th17 cells and therapeutic implications. Mediators Inflamm (2015) 0.92
Alternative activation of human plasmacytoid DCs in vitro and in melanoma lesions: involvement of LAG-3. J Invest Dermatol (2014) 0.91
Intrafollicular location of marginal zone/CD1d(hi) B cells is associated with autoimmune pathology in a mouse model of lupus. Lab Invest (2008) 0.91
The Proteomic Landscape of Human Ex Vivo Regulatory and Conventional T Cells Reveals Specific Metabolic Requirements. Immunity (2016) 0.91
Homeostasis and function of regulatory T cells (Tregs) in vivo: lessons from TCR-transgenic Tregs. Immunol Rev (2014) 0.89
Clinical utilization of chemokines to combat cancer: the double-edged sword. Expert Rev Vaccines (2007) 0.89
CD4+ CD25+ Foxp3- T-regulatory cells produce both gamma interferon and interleukin-10 during acute severe murine spotted fever rickettsiosis. Infect Immun (2009) 0.88
Direct contact of platelets and their released products exert different effects on human dendritic cell maturation. BMC Immunol (2008) 0.88
Tumor-infiltrating dendritic cells in cancer pathogenesis. J Immunol (2015) 0.87
IL-10-produced by human transitional B-cells down-regulates CD86 expression on B-cells leading to inhibition of CD4(+)T-cell responses. Sci Rep (2016) 0.87
Alcohol exposure impairs myeloid dendritic cell function in rhesus macaques. Alcohol Clin Exp Res (2009) 0.86
Autologous MUC1-specific Th1 effector cell immunotherapy induces differential levels of systemic TReg cell subpopulations that result in increased ovarian cancer patient survival. Clin Immunol (2009) 0.86
FoxP3⁺ regulatory T cells attenuate experimental necrotizing enterocolitis. PLoS One (2013) 0.85
The Role of Dendritic Cell Subsets and Innate Immunity in the Pathogenesis of Type 1 Diabetes and Other Autoimmune Diseases. Front Immunol (2015) 0.85
DNA methylation dynamics during ex vivo differentiation and maturation of human dendritic cells. Epigenetics Chromatin (2014) 0.85
Mechanistic insight into the TH1-biased immune response to recombinant subunit vaccines delivered by probiotic bacteria-derived outer membrane vesicles. PLoS One (2014) 0.84
Helicobacter pylori induces in-vivo expansion of human regulatory T cells through stimulating interleukin-1β production by dendritic cells. Clin Exp Immunol (2012) 0.83
Deletion of Fibrinogen-like Protein 2 (FGL-2), a Novel CD4+ CD25+ Treg Effector Molecule, Leads to Improved Control of Echinococcus multilocularis Infection in Mice. PLoS Negl Trop Dis (2015) 0.83
What are the molecules involved in regulatory T-cells induction by dendritic cells in cancer? Clin Dev Immunol (2013) 0.82
Disease activity in systemic lupus erythematosus is associated with an altered expression of low-affinity Fc gamma receptors and costimulatory molecules on dendritic cells. Immunology (2009) 0.82
B-CLL cells acquire APC- and CTL-like phenotypic characteristics after stimulation with CpG ODN and IL-21. Int Immunol (2014) 0.81
Efficiency of T-cell costimulation by CD80 and CD86 cross-linking correlates with calcium entry. Immunology (2009) 0.81
Dysregulated co-stimulatory molecule expression in a Sjögren's syndrome mouse model with potential implications by microRNA-146a. Mol Immunol (2015) 0.80
Differential response of BDCA-1+ and BDCA-3+ myeloid dendritic cells to respiratory syncytial virus infection. Respir Res (2013) 0.78
Tregs utilize beta-galactoside-binding protein to transiently inhibit PI3K/p21ras activity of human CD8+ T cells to block their TCR-mediated ERK activity and proliferation. Brain Behav Immun (2009) 0.77
The Polyunsaturated Fatty Acids Arachidonic Acid and Docosahexaenoic Acid Induce Mouse Dendritic Cells Maturation but Reduce T-Cell Responses In Vitro. PLoS One (2015) 0.76
Paramyxovirus infection regulates T cell responses by BDCA-1+ and BDCA-3+ myeloid dendritic cells. PLoS One (2014) 0.76
Cell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand Recognition. Front Immunol (2016) 0.75
Human β Defensin-3 Increases CD86 Expression on Monocytes by Activating the ATP-Gated Channel P2X7. J Immunol (2015) 0.75
Characterization of Bone Marrow-Derived Dendritic Cells Developed in Serum-Free Media and their Ability to Prevent Type 1 Diabetes in Nonobese Diabetic Mice. J Blood Disord Transfus (2014) 0.75
The Importance of Dendritic Cells in Maintaining Immune Tolerance. J Immunol (2017) 0.75
CTLA-4/CD80 pathway regulates T cell infiltration into pancreatic cancer. Cancer Immunol Immunother (2017) 0.75
High-dimensional, single-cell characterization of the brain's immune compartment. Nat Neurosci (2017) 0.75
Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. Science (2011) 4.96
Normal human pregnancy is associated with an elevation in the immune suppressive CD25+ CD4+ regulatory T-cell subset. Immunology (2004) 2.51
Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease. J Steroid Biochem Mol Biol (2007) 2.42
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses. Nat Rev Immunol (2011) 2.36
1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3. J Immunol (2009) 2.22
HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC. PLoS Pathog (2009) 2.15
CTLA4 gene polymorphism and autoimmunity. Immunol Rev (2005) 1.91
Low-dose peptide tolerance therapy of lupus generates plasmacytoid dendritic cells that cause expansion of autoantigen-specific regulatory T cells and contraction of inflammatory Th17 cells. J Immunol (2007) 1.88
Low-level hypermutation in T cell-independent germinal centers compared with high mutation rates associated with T cell-dependent germinal centers. J Exp Med (2002) 1.69
Ctla-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity. J Immunol (2009) 1.66
Functional equivalence and evolutionary convergence in complex communities of microbial sponge symbionts. Proc Natl Acad Sci U S A (2012) 1.63
Follicular helper T cell signature in type 1 diabetes. J Clin Invest (2014) 1.61
The accuracy of dermatology network physician directories posted by Medicare Advantage health plans in an era of narrow networks. JAMA Dermatol (2014) 1.50
Acquisition of suppressive function by activated human CD4+ CD25- T cells is associated with the expression of CTLA-4 not FoxP3. J Immunol (2008) 1.45
Alloimmunity-induced autoimmunity as a potential mechanism in the pathogenesis of chronic rejection of human lung allografts. J Heart Lung Transplant (2011) 1.37
Exocytosis of CTLA-4 is dependent on phospholipase D and ADP ribosylation factor-1 and stimulated during activation of regulatory T cells. J Immunol (2005) 1.36
Availability of 25-hydroxyvitamin D(3) to APCs controls the balance between regulatory and inflammatory T cell responses. J Immunol (2012) 1.35
What's the difference between CD80 and CD86? Trends Immunol (2003) 1.29
Inhibition of human T cell proliferation by CTLA-4 utilizes CD80 and requires CD25+ regulatory T cells. Eur J Immunol (2002) 1.26
Cutting edge: cell-extrinsic immune regulation by CTLA-4 expressed on conventional T cells. J Immunol (2012) 1.19
Marine microbial symbiosis heats up: the phylogenetic and functional response of a sponge holobiont to thermal stress. ISME J (2013) 1.12
Using chimeric mice with humanized livers to predict human drug metabolism and a drug-drug interaction. J Pharmacol Exp Ther (2012) 1.11
The anti-hepatitis C agent nitazoxanide induces phosphorylation of eukaryotic initiation factor 2alpha via protein kinase activated by double-stranded RNA activation. Gastroenterology (2009) 1.05
Fractures between the ages of 20 and 50 years increase women's risk of subsequent fractures. Arch Intern Med (2002) 1.03
Constitutive clathrin-mediated endocytosis of CTLA-4 persists during T cell activation. J Biol Chem (2012) 1.02
Integration of CD28 and CTLA-4 function results in differential responses of T cells to CD80 and CD86. Eur J Immunol (2006) 0.99
Gender and ethnic differences in the prevalence of type 2 diabetes among Asian subgroups in California. J Diabetes Complications (2013) 0.96
Distinct T cell recognition of naturally processed and cryptic epitopes within the immunodominant 35-55 region of myelin oligodendrocyte glycoprotein. J Neuroimmunol (2006) 0.95
Apigenin, a non-mutagenic dietary flavonoid, suppresses lupus by inhibiting autoantigen presentation for expansion of autoreactive Th1 and Th17 cells. Arthritis Res Ther (2009) 0.92
Ankyrin-repeat proteins from sponge symbionts modulate amoebal phagocytosis. Mol Ecol (2013) 0.87
Endothelin-1 regulates proliferative responses, both alone and synergistically with PDGF, in rat tracheal smooth muscle cells. Cell Physiol Biochem (2006) 0.85
Acneiform eruptions: a common cutaneous toxicity of the MEK inhibitor trametinib. Australas J Dermatol (2013) 0.83
Efficacy of a jellyfish sting inhibitor in preventing jellyfish stings in normal volunteers. Wilderness Environ Med (2004) 0.83
Direct synthesis of branched gold nanocrystals and their transformation into spherical nanoparticles. J Phys Chem B (2006) 0.82
Harnessing single cell sorting to identify cell division genes and regulators in bacteria. PLoS One (2013) 0.82
The histone peptide H4 71-94 alone is more effective than a cocktail of peptide epitopes in controlling lupus: immunoregulatory mechanisms. J Clin Immunol (2011) 0.82
Identification of novel HSP90α/β isoform selective inhibitors using structure-based drug design. demonstration of potential utility in treating CNS disorders such as Huntington's disease. J Med Chem (2014) 0.81
pH-driven assembly of various supported lipid platforms: a comparative study on silicon oxide and titanium oxide. Langmuir (2011) 0.80
Factors associated with depression and anxiety among patients attending community-based methadone maintenance treatment in China. Addiction (2015) 0.80
Identification of a secondary zinc-binding site in staphylococcal enterotoxin C2. Implications for superantigen recognition. J Biol Chem (2003) 0.80
Arteriovenous malformation: a potential cause of ischaemic colitis. ANZ J Surg (2013) 0.79
Dendritic cells, antigen distribution and the initiation of primary immune responses to self and non-self antigens. Semin Cancer Biol (2002) 0.79
Do patients with inflammatory bowel disease want genetic testing? Inflamm Bowel Dis (2006) 0.79
Does low vitamin D amplify the association of COPD with total and cardiovascular disease mortality? Clin Cardiol (2014) 0.78
Comparison of the intracellular trafficking itinerary of ctla-4 orthologues. PLoS One (2013) 0.76
Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J Med Chem (2014) 0.75
Dendritic cells derived from bone marrow cells fail to acquire and present major histocompatibility complex antigens from other dendritic cells. Immunology (2008) 0.75
Clinical Practice Guideline: Safe Medication Use in the ICU. Crit Care Med (2017) 0.75
Regulatory T cells and COPD. Thorax (2013) 0.75
Correction: A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding. J Immunol (2017) 0.75
Prognostic value of initial elevation in cardiac troponin I level in critically ill patients without acute coronary syndrome. Crit Care Nurse (2015) 0.75
Gender and Ethnic Diversity in Academic PM&R Faculty: National Trend Analysis of Two Decades. Am J Phys Med Rehabil (2017) 0.75
Executive Summary: Clinical Practice Guideline: Safe Medication Use in the ICU. Crit Care Med (2017) 0.75
Immune regulation by CTLA-4--relevance to autoimmune diabetes in a transgenic mouse model. Diabetes Metab Res Rev (2011) 0.75