Published in J Immunol on March 01, 2004
Intranasal delivery of cholera toxin induces th17-dominated T-cell response to bystander antigens. PLoS One (2009) 1.46
Maturation of monocyte-derived dendritic cells with Toll-like receptor 3 and 7/8 ligands combined with prostaglandin E2 results in high interleukin-12 production and cell migration. Cancer Immunol Immunother (2008) 1.15
IL-12 produced by dendritic cells augments CD8+ T cell activation through the production of the chemokines CCL1 and CCL17. J Immunol (2008) 1.11
Reciprocal responsiveness to interleukin-12 and interferon-alpha specifies human CD8+ effector versus central memory T-cell fates. Blood (2009) 1.08
Priming of naive CD8+ T cells in the presence of IL-12 selectively enhances the survival of CD8+CD62Lhi cells and results in superior anti-tumor activity in a tolerogenic murine model. Cancer Immunol Immunother (2007) 0.95
Ex vivo interleukin-12-priming during CD8(+) T cell activation dramatically improves adoptive T cell transfer antitumor efficacy in a lymphodepleted host. J Am Coll Surg (2012) 0.95
Cross-presentation of cell-associated antigens by mouse splenic dendritic cell populations. Front Immunol (2012) 0.93
The roles of IL-12 and IL-23 in CD8+ T cell-mediated immunity against Listeria monocytogenes: Insights from a DC vaccination model. Cell Immunol (2010) 0.86
Early Decision: Effector and Effector Memory T Cell Differentiation in Chronic Infection. Curr Immunol Rev (2013) 0.85
Treatment of lymphoma with adoptively transferred T cells. Expert Opin Biol Ther (2009) 0.85
Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8(+) T cells. Cancer Immunol Immunother (2015) 0.84
Induction of protective cytotoxic T-cell responses by a B-cell-based cellular vaccine requires stable expression of antigen. Gene Ther (2009) 0.83
Pharmacological inhibition of TPL2/MAP3K8 blocks human cytotoxic T lymphocyte effector functions. PLoS One (2014) 0.81
Blimp-1 connects the intrinsic and extrinsic regulation of T cell homeostasis. J Clin Immunol (2007) 0.80
Interleukin-12 up-regulates perforin- and Fas-mediated lymphokine-activated killer activity by intestinal intraepithelial lymphocytes. Clin Exp Immunol (2004) 0.80
Inducing efficient cross-priming using antigen-coated yeast particles. J Immunother (2008) 0.79
Early coupled up-regulation of interleukin-12 receptor beta-1 in CD8+ central memory and effector T cells for better clinical outcomes in liver transplant recipients. Clin Exp Immunol (2015) 0.78
CD43 Expression Regulated by IL-12 Signaling Is Associated with Survival of CD8 T Cells. Immune Netw (2010) 0.78
Loss of T cell-mediated antitumor immunity after construct-specific downregulation of retrovirally encoded T-cell receptor expression in vivo. Cancer Gene Ther (2008) 0.78
Antigen-induced Erk1/2 activation regulates Ets-1-mediated sensitization of CD8+ T cells for IL-12 responses. J Leukoc Biol (2009) 0.77
The use of growth factors to modulate the activities of antigen-specific CD8+ T cells in vitro. J Med Life (2011) 0.76
Oncolytic measles virus encoding interleukin-12 mediates potent antitumor effects through T cell activation. Oncoimmunology (2017) 0.75
IL-12 conditioning improves retrovirally mediated transduction efficiency of CD8+ T cells. Cancer Gene Ther (2015) 0.75
Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity (2007) 10.83
Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection. Proc Natl Acad Sci U S A (2010) 4.56
Internet addiction in Korean adolescents and its relation to depression and suicidal ideation: a questionnaire survey. Int J Nurs Stud (2006) 3.34
Stimulation history dictates memory CD8 T cell phenotype: implications for prime-boost vaccination. J Immunol (2006) 3.29
Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}. Proc Natl Acad Sci U S A (2006) 3.04
Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection. Science (2009) 2.64
Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells. Immunity (2011) 2.49
Mesenchymal stem cell injections improve symptoms of knee osteoarthritis. Arthroscopy (2013) 2.42
STAT3 and NF-kappaB signal pathway is required for IL-23-mediated IL-17 production in spontaneous arthritis animal model IL-1 receptor antagonist-deficient mice. J Immunol (2006) 2.31
Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases. Genome Res (2013) 2.28
Gene therapy using TRAIL-secreting human umbilical cord blood-derived mesenchymal stem cells against intracranial glioma. Cancer Res (2008) 1.88
IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection. Proc Natl Acad Sci U S A (2008) 1.84
Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection. J Virol (2009) 1.77
Fibroblast growth factor receptor 1 gene amplification is associated with poor survival and cigarette smoking dosage in patients with resected squamous cell lung cancer. J Clin Oncol (2012) 1.67
TMPRSS2 and TMPRSS4 facilitate trypsin-independent spread of influenza virus in Caco-2 cells. J Virol (2010) 1.66
Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection. Proc Natl Acad Sci U S A (2011) 1.62
PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice. J Clin Invest (2010) 1.53
Distinct clinical features and outcomes in never-smokers with nonsmall cell lung cancer who harbor EGFR or KRAS mutations or ALK rearrangement. Cancer (2011) 1.49
T cell homeostasis. Immunol Cell Biol (2008) 1.45
PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells. J Clin Invest (2013) 1.42
High EGFR gene copy number and skin rash as predictive markers for EGFR tyrosine kinase inhibitors in patients with advanced squamous cell lung carcinoma. Clin Cancer Res (2012) 1.39
Tumor-infiltrating regulatory T cells delineated by upregulation of PD-1 and inhibitory receptors. Cell Immunol (2012) 1.37
Activation of the Trk signaling pathway by extracellular zinc. Role of metalloproteinases. J Biol Chem (2005) 1.26
Immune regulation and control of regulatory T cells by OX40 and 4-1BB. Cytokine Growth Factor Rev (2008) 1.21
4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection. J Immunol (2011) 1.20
Interleukin-21 is a critical cytokine for the generation of virus-specific long-lived plasma cells. J Virol (2013) 1.18
Activation of IL-6R/JAK1/STAT3 signaling induces de novo resistance to irreversible EGFR inhibitors in non-small cell lung cancer with T790M resistance mutation. Mol Cancer Ther (2012) 1.16
A major histocompatibility complex class I-dependent subset of memory phenotype CD8+ cells. J Exp Med (2006) 1.15
Costimulation of mast cells by 4-1BB, a member of the tumor necrosis factor receptor superfamily, with the high-affinity IgE receptor. Blood (2005) 1.14
Measles virus-dendritic cell interaction via SLAM inhibits innate immunity: selective signaling through TLR4 but not other TLRs mediates suppression of IL-12 synthesis. Virology (2006) 1.10
Enhancement of vaccine-induced primary and memory CD8(+) T-cell responses by soluble PD-1. J Immunother (2011) 1.08
Recruitment of monocytes/macrophages in different tumor microenvironments. Biochim Biophys Acta (2012) 1.07
Clinicopathologic features and outcomes of metaplastic breast carcinoma: comparison with invasive ductal carcinoma of the breast. Yonsei Med J (2010) 1.05
Cotyledonoid dissecting leiomyoma of the uterus: a case report and review of the literature. J Korean Med Sci (2002) 1.05
Tumor necrosis factor/tumor necrosis factor receptor family members that positively regulate immunity. Int J Hematol (2006) 1.04
Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation. Oncogene (2003) 1.04
Lung cancer in never smokers: change of a mindset in the molecular era. Lung Cancer (2011) 1.02
Transcriptional regulation of human excitatory amino acid transporter 1 (EAAT1): cloning of the EAAT1 promoter and characterization of its basal and inducible activity in human astrocytes. J Neurochem (2003) 1.01
IL-23 induces receptor activator of NF-kappaB ligand expression on CD4+ T cells and promotes osteoclastogenesis in an autoimmune arthritis model. J Immunol (2008) 1.00
The lymphopenic environment of CD132 (common gamma-chain)-deficient hosts elicits rapid homeostatic proliferation of naive T cells via IL-15. J Immunol (2008) 0.99
Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8(+) T cells. Eur J Immunol (2010) 0.99
Mechanism of T cell exhaustion in a chronic environment. BMB Rep (2011) 0.98
Optimal induction of HPV DNA vaccine-induced CD8+ T cell responses and therapeutic antitumor effect by antigen engineering and electroporation. Vaccine (2009) 0.95
Egr2 induced during DC development acts as an intrinsic negative regulator of DC immunogenicity. Eur J Immunol (2013) 0.95
IL-7/anti-IL-7 mAb complexes augment cytokine potency in mice through association with IgG-Fc and by competition with IL-7R. Blood (2013) 0.94
The role of NADPH oxidase, neuronal nitric oxide synthase and poly(ADP ribose) polymerase in oxidative neuronal death induced in cortical cultures by brain-derived neurotrophic factor and neurotrophin-4/5. J Neurochem (2002) 0.94
Overexpression of hepatitis C virus NS5A protein induces chromosome instability via mitotic cell cycle dysregulation. J Mol Biol (2006) 0.94
IL-23 induces stronger sustained CTL and Th1 immune responses than IL-12 in hepatitis C virus envelope protein 2 DNA immunization. J Immunol (2004) 0.92
Respiratory monitoring by porphyrin modified quartz crystal microbalance sensors. Sensors (Basel) (2011) 0.92
Treatment failure in intracranial primary germinomas. Childs Nerv Syst (2007) 0.90
Osteonecrosis associated with dental implants in patients undergoing bisphosphonate treatment. Clin Oral Implants Res (2012) 0.89
The maturity of tissue-engineered cartilage in vitro affects the repairability for osteochondral defect. Tissue Eng Part A (2011) 0.89
In vivo action of IL-27: reciprocal regulation of Th17 and Treg cells in collagen-induced arthritis. Exp Mol Med (2013) 0.89
Negative regulation of type I IFN expression by OASL1 permits chronic viral infection and CD8⁺ T-cell exhaustion. PLoS Pathog (2013) 0.88
Murine thymic stromal lymphopoietin promotes the differentiation of regulatory T cells from thymic CD4(+)CD8(-)CD25(-) naïve cells in a dendritic cell-independent manner. Immunol Cell Biol (2007) 0.88
Enhancement of interleukin-12 gene-based tumor immunotherapy by the reduced secretion of p40 subunit and the combination with farnesyltransferase inhibitor. Hum Gene Ther (2005) 0.88
Self-assembly of amorphous calcium carbonate microlens arrays. Nat Commun (2012) 0.87
p53 deficiency and defective mitotic checkpoint in proliferating T lymphocytes increase chromosomal instability through aberrant exit from mitotic arrest. J Leukoc Biol (2003) 0.86
Dual effects of hepatitis B virus X protein on the regulation of cell-cycle control depending on the status of cellular p53. J Gen Virol (2002) 0.84
Delivery of IL-12p40 ameliorates DSS-induced colitis by suppressing IL-17A expression and inflammation in the intestinal mucosa. Clin Immunol (2012) 0.84
The role of interleukin-2 in memory CD8 cell differentiation. Adv Exp Med Biol (2010) 0.84
Direct endothelial junction restoration results in significant tumor vascular normalization and metastasis inhibition in mice. Oncotarget (2014) 0.84
Signal amplification by enzymatic reaction in an immunosensor based on localized surface plasmon resonance (LSPR). Sensors (Basel) (2010) 0.83
Cloning and characterization of the 3'-untranslated region of the human excitatory amino acid transporter 2 transcript. J Neurochem (2003) 0.83
Marked enhancement of antigen-specific T-cell responses by IL-7-fused nonlytic, but not lytic, Fc as a genetic adjuvant. Eur J Immunol (2010) 0.83
KIAA1114, a full-length protein encoded by the trophinin gene, is a novel surface marker for isolating tumor-initiating cells of multiple hepatocellular carcinoma subtypes. Oncotarget (2014) 0.83
Breakdown in repression of IFN-γ mRNA leads to accumulation of self-reactive effector CD8+ T cells. J Immunol (2012) 0.83
Codelivery of IL-7 Augments Multigenic HCV DNA Vaccine-induced Antibody as well as Broad T Cell Responses in Cynomolgus Monkeys. Immune Netw (2010) 0.82
Enhanced immunogenicity and protective efficacy with the use of interleukin-12-encapsulated microspheres plus AS01B in tuberculosis subunit vaccination. Infect Immun (2006) 0.82
Mind bomb-1 in dendritic cells is specifically required for Notch-mediated T helper type 2 differentiation. PLoS One (2012) 0.82
Differentiation of antigen-specific T cells with limited functional capacity during Mycobacterium tuberculosis infection. Infect Immun (2013) 0.82
The impact of cigarette smoking on the frequency of and qualitative differences in KRAS mutations in Korean patients with lung adenocarcinoma. Yonsei Med J (2013) 0.82
Development and evaluation of new primers for PCR-based identification of type II fimA of Porphyromonas gingivalis. FEMS Immunol Med Microbiol (2012) 0.82
Fiber optic long period grating sensors with a nanoassembled mesoporous film of SiO2 nanoparticles. Opt Express (2010) 0.81
A phase I trial of gefitinib and nimotuzumab in patients with advanced non-small cell lung cancer (NSCLC). Lung Cancer (2012) 0.80
Ligand supported homology modeling and docking evaluation of CCR2: docked pose selection by consensus scoring. J Mol Model (2011) 0.80
Interleukin-27 suppresses osteoclastogenesis via induction of interferon-γ. Immunology (2012) 0.80
Self-assembly and imprinting of macrocyclic molecules in layer-by-layered TiO2 ultrathin films. Anal Chim Acta (2013) 0.80
In vivo kinetics and biodistribution of a HIV-1 DNA vaccine after administration in mice. Arch Pharm Res (2003) 0.79
Self/non-self discrimination and the problem of keeping T cells alive. Immunol Cell Biol (2007) 0.79
Co-immunization of plasmid DNA encoding IL-12 and IL-18 with Bacillus Calmette-Guérin vaccine against progressive tuberculosis. Yonsei Med J (2011) 0.79
Subacromial impingement syndrome secondary to scapulothoracic dyskinesia. Knee Surg Sports Traumatol Arthrosc (2011) 0.79
Short-term overlap lamivudine treatment with adefovir dipivoxil in patients with lamivudine-resistant chronic hepatitis B. World J Gastroenterol (2008) 0.78
Apoptosis and proliferation in paired primary colorectal adenocarcinomas and their liver metastases. Yonsei Med J (2004) 0.78
Morphological control of CaCO3 films with large area: effect of additives and self-organization under atmospheric conditions. J Colloid Interface Sci (2010) 0.78
Nonlytic Fc-fused IL-7 synergizes with Mtb32 DNA vaccine to enhance antigen-specific T cell responses in a therapeutic model of tuberculosis. Vaccine (2013) 0.78
Design of highly efficient receptor sites by combination of cyclodextrin units and molecular cavity in TiO2 ultrathin layer. Biosens Bioelectron (2006) 0.78
Simultaneous monitoring of humidity and chemical changes using quartz crystal microbalance sensors modified with nano-thin films. Anal Sci (2011) 0.78
Unified immune modulation by 4-1BB triggering leads to diverse effects on disease progression in vivo. Cytokine (2011) 0.78
Mycelial Extract of Phellinus linteus Induces Cell Death in A549 Lung Cancer Cells and Elevation of Nitric Oxide in Raw 264.7 Macrophage Cells. Mycobiology (2006) 0.78
Tendon trap technique for rotator cuff repair. Orthopedics (2012) 0.77
Correction: PD-1 Upregulated on Regulatory T Cells during Chronic Virus Infection Enhances the Suppression of CD8+ T Cell Immune Response via the Interaction with PD-L1 Expressed on CD8+ T Cells. J Immunol (2015) 0.77
Differential regulation of antigen-specific CD8+ T cell responses by IL-12p40 in a dose-dependent manner. J Immunol (2008) 0.77
PFHxS induces apoptosis of neuronal cells via ERK1/2-mediated pathway. Chemosphere (2013) 0.77
Rod-like architecture and helicity of the poly(C)/schizophyllan complex observed by AFM and SEM. Carbohydr Res (2004) 0.77
Comparison of gene expression between mandibular and iliac bone-derived cells. Clin Oral Investig (2014) 0.77
Noninvasive measurement of membrane potential modulation in microorganisms: photosynthesis in green algae. ACS Nano (2013) 0.76