Published in J Cell Physiol on April 01, 2004
In vitro and in vivo evidence for shear-induced activation of latent transforming growth factor-beta1. Blood (2008) 1.94
MicroRNA-24 regulates cardiac fibrosis after myocardial infarction. J Cell Mol Med (2012) 1.35
Review of the activation of TGF-beta in immunity. J Leukoc Biol (2008) 1.35
Deficiency in microfibril-associated glycoprotein-1 leads to complex phenotypes in multiple organ systems. J Biol Chem (2008) 1.26
Targeting the TGF-beta1 pathway to prevent normal tissue injury after cancer therapy. Oncologist (2010) 1.23
Platelet activation by collagen provides sustained release of anabolic cytokines. Am J Sports Med (2011) 1.15
A sequential, multiple-treatment, targeted approach to reduce wound healing and failure of glaucoma filtration surgery in a rabbit model (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc (2006) 1.10
TGF-beta signaling is required for multiple processes during Xenopus tail regeneration. Dev Biol (2008) 1.06
Platelet depletion in mice increases mortality after thermal injury. Blood (2006) 1.00
TGF-β3 modulates the inflammatory environment and reduces scar formation following vocal fold mucosal injury in rats. Dis Model Mech (2013) 0.97
Targeting TGFβ signaling in subchondral bone and articular cartilage homeostasis. Trends Pharmacol Sci (2014) 0.96
In vitro and in vivo evidence that thrombospondin-1 (TSP-1) contributes to stirring- and shear-dependent activation of platelet-derived TGF-beta1. PLoS One (2009) 0.93
Extracellular heat shock protein HSP90beta secreted by MG63 osteosarcoma cells inhibits activation of latent TGF-beta1. Biochem Biophys Res Commun (2010) 0.92
Suppression of latent transforming growth factor (TGF)-beta1 restores growth inhibitory TGF-beta signaling through microRNAs. J Biol Chem (2011) 0.90
Role of miR-24, Furin, and Transforming Growth Factor-β1 Signal Pathway in Fibrosis After Cardiac Infarction. Med Sci Monit (2017) 0.76
Stromal Modulators of TGF-β in Cancer. J Clin Med (2017) 0.76
Thrombocytopenia May Mediate Disease Severity in Plasmodium falciparum Malaria Through Reduced Transforming Growth Factor Beta-1 Regulation of Proinflammatory and Anti-inflammatory Cytokines. Pediatr Infect Dis J (2015) 0.76
Clinical Benefits of Biochemical Markers of Fibrosis in Egyptian Children With Chronic Liver Diseases. Gastroenterology Res (2010) 0.75
Exome sequencing-based copy-number variation and loss of heterozygosity detection: ExomeCNV. Bioinformatics (2011) 5.45
Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis. J Cell Biol (2003) 2.68
Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17. J Exp Med (2009) 2.28
Plasminogen activation and cancer. Thromb Haemost (2005) 2.21
RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells. Mol Cell (2009) 2.11
Prophylactic administration of avotermin for improvement of skin scarring: three double-blind, placebo-controlled, phase I/II studies. Lancet (2009) 2.08
Severely impaired wound healing in the collagenase-resistant mouse. J Invest Dermatol (2003) 1.77
Tissue engineering of replacement skin: the crossroads of biomaterials, wound healing, embryonic development, stem cells and regeneration. J R Soc Interface (2007) 1.68
Two distinct expression patterns of urokinase, urokinase receptor and plasminogen activator inhibitor-1 in colon cancer liver metastases. Int J Cancer (2009) 1.66
Visual analogue scale scoring and ranking: a suitable and sensitive method for assessing scar quality? Plast Reconstr Surg (2006) 1.58
Rhodocetin antagonizes stromal tumor invasion in vitro and other alpha2beta1 integrin-mediated cell functions. Matrix Biol (2002) 1.57
Reduced metastasis of transgenic mammary cancer in urokinase-deficient mice. Int J Cancer (2005) 1.48
Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy. J Cell Biol (2005) 1.42
Metabolome, transcriptome, and bioinformatic cis-element analyses point to HNF-4 as a central regulator of gene expression during enterocyte differentiation. Physiol Genomics (2006) 1.42
Myofibroblast differentiation is induced in keratinocyte-fibroblast co-cultures and is antagonistically regulated by endogenous transforming growth factor-beta and interleukin-1. Am J Pathol (2004) 1.39
Overexpression of the cell adhesion molecule L1 is associated with metastasis in cutaneous malignant melanoma. Eur J Cancer (2002) 1.38
Stromal cells associated with early invasive foci in human mammary ductal carcinoma in situ coexpress urokinase and urokinase receptor. Int J Cancer (2007) 1.24
Scar-improving efficacy of avotermin administered into the wound margins of skin incisions as evaluated by a randomized, double-blind, placebo-controlled, phase II clinical trial. Plast Reconstr Surg (2010) 1.24
Avotermin for scar improvement following scar revision surgery: a randomized, double-blind, within-patient, placebo-controlled, phase II clinical trial. Plast Reconstr Surg (2011) 1.22
CEACAM1 expression in cutaneous malignant melanoma predicts the development of metastatic disease. J Clin Oncol (2002) 1.21
Gab2-mediated signaling promotes melanoma metastasis. Am J Pathol (2009) 1.21
Regeneration of the ear after wounding in different mouse strains is dependent on the severity of wound trauma. Dev Dyn (2003) 1.17
The dynamic rotation of Langer's lines on facial expression. J Plast Reconstr Aesthet Surg (2006) 1.15
The plasminogen fibrinolytic pathway is required for hematopoietic regeneration. Cell Stem Cell (2007) 1.15
Characterizing regeneration in the vertebrate ear. J Anat (2006) 1.14
MMP-9 deficiency affects axonal outgrowth, migration, and apoptosis in the developing cerebellum. Mol Cell Neurosci (2003) 1.14
The cellular biology of flexor tendon adhesion formation: an old problem in a new paradigm. Am J Pathol (2009) 1.13
ECM degrading proteases and tissue remodelling in the mammary gland. Bioessays (2005) 1.10
The development of archosaurian first-generation teeth in a chicken mutant. Curr Biol (2006) 1.10
Prevention and reduction of scarring in the skin by Transforming Growth Factor beta 3 (TGFbeta3): from laboratory discovery to clinical pharmaceutical. J Biomater Sci Polym Ed (2008) 1.10
MMP-9 is differentially expressed in primary human colorectal adenocarcinomas and their metastases. Mol Cancer Res (2006) 1.08
Skin tension or skin compression? Small circular wounds are likely to shrink, not gape. J Plast Reconstr Aesthet Surg (2007) 1.08
Targeting genes for treatment in idiopathic pulmonary fibrosis: challenges and opportunities, promises and pitfalls. Proc Am Thorac Soc (2006) 1.07
Genetic susceptibility to keloid disease and hypertrophic scarring: transforming growth factor beta1 common polymorphisms and plasma levels. Plast Reconstr Surg (2003) 1.06
Bioengineering skin using mechanisms of regeneration and repair. Biomaterials (2007) 1.05
The epidermal basement membrane is a composite of separate laminin- or collagen IV-containing networks connected by aggregated perlecan, but not by nidogens. J Biol Chem (2012) 1.04
Microscopic and histological examination of the mouse hindpaw digit and flexor tendon arrangement with 3D reconstruction. J Anat (2006) 1.03
Gene expression profiles in stages II and III colon cancers: application of a 128-gene signature. Int J Colorectal Dis (2012) 1.01
Location of injury influences the mechanisms of both regeneration and repair within the MRL/MpJ mouse. J Anat (2006) 0.99
A functional overlap of plasminogen and MMPs regulates vascularization during placental development. Development (2003) 0.98
GAB2 amplifications refine molecular classification of melanoma. Clin Cancer Res (2009) 0.97
Integrins as antimetastatic targets of RGD-independent snake venom components in liver metastasis [corrected]. Neoplasia (2008) 0.97
Cell-specific gene expression in patients with usual interstitial pneumonia. Am J Respir Crit Care Med (2006) 0.96
Structural analysis and tissue localization of human C4.4A: a protein homologue of the urokinase receptor. Biochem J (2004) 0.96
ADAMTS8 and ADAMTS15 expression predicts survival in human breast carcinoma. Int J Cancer (2006) 0.95
New therapeutics for the prevention and reduction of scarring. Drug Discov Today (2008) 0.95
Experimental manipulation of transforming growth factor-beta isoforms significantly affects adhesion formation in a murine surgical model. Am J Pathol (2005) 0.94
Identification of a novel mitochondrial mutation in Dupuytren's disease using multiplex DHPLC. Plast Reconstr Surg (2005) 0.93
Decreased expression of inhibitory SMAD6 and SMAD7 in keloid scarring. J Plast Reconstr Aesthet Surg (2006) 0.93
Inactivation of active and latent transforming growth factor beta by free thiols: potential redox regulation of biological action. Int J Biochem Cell Biol (2006) 0.93
Genetic susceptibility to dupuytren disease: association of Zf9 transcription factor gene. Plast Reconstr Surg (2003) 0.93
Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells. Biol Chem (2008) 0.92
Maturation of the human scar: an observational study. Plast Reconstr Surg (2008) 0.92
Urokinase plasminogen activator receptor is expressed in invasive cells in gastric carcinomas from high- and low-risk countries. Int J Cancer (2010) 0.92
Scarring impedes regeneration at sites of peripheral nerve repair. Neuroreport (2006) 0.91
A comparative study of the structure of human and murine greater omentum. Anat Embryol (Berl) (2005) 0.91
Leading-edge myofibroblasts in human colon cancer express plasminogen activator inhibitor-1. Am J Clin Pathol (2004) 0.90
The effect of antibodies to TGF-beta1 and TGF-beta2 at a site of sciatic nerve repair. J Peripher Nerv Syst (2006) 0.90
Profibrinolytic effects of metalloproteinases during skin wound healing in the absence of plasminogen. J Invest Dermatol (2008) 0.90
No effect of NGAL/lipocalin-2 on aggressiveness of cancer in the MMTV-PyMT/FVB/N mouse model for breast cancer. PLoS One (2012) 0.90
Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts - role of TGFβ1 levels and RhoA activity. J Cell Sci (2010) 0.90
Discovery and development of avotermin (recombinant human transforming growth factor beta 3): a new class of prophylactic therapeutic for the improvement of scarring. Wound Repair Regen (2011) 0.90
The developmentally regulated neural crest-associated glycotope HNK-1 predicts metastasis in cutaneous malignant melanoma. J Pathol (2004) 0.89
Studies of transforming growth factors beta 1-3 and their receptors I and II in fibroblast of keloids and hypertrophic scars. Acta Derm Venereol (2005) 0.89
Peripheral nerve regeneration in the MRL/MpJ ear wound model. J Anat (2010) 0.89
Lack of plasminogen leads to milk stasis and premature mammary gland involution during lactation. Dev Biol (2006) 0.89
Antibody-mediated targeting of the urokinase-type plasminogen activator proteolytic function neutralizes fibrinolysis in vivo. J Biol Chem (2008) 0.89
A synthetic gene increases TGFβ3 accumulation by 75-fold in tobacco chloroplasts enabling rapid purification and folding into a biologically active molecule. Plant Biotechnol J (2011) 0.88
Murine monoclonal antibodies against murine uPA receptor produced in gene-deficient mice: inhibitory effects on receptor-mediated uPA activity in vitro and in vivo. Thromb Haemost (2007) 0.88
Successful ovulation in plasminogen-deficient mice treated with the broad-spectrum matrix metalloproteinase inhibitor galardin. Dev Biol (2006) 0.87
Matrix metalloproteinase 13 is induced in fibroblasts in polyomavirus middle T antigen-driven mammary carcinoma without influencing tumor progression. PLoS One (2008) 0.87
Neutrophil gelatinase-associated lipocalin (NGAL/Lcn2) is upregulated in gastric mucosa infected with Helicobacter pylori. Virchows Arch (2009) 0.87
Therapeutic improvement of scarring: mechanisms of scarless and scar-forming healing and approaches to the discovery of new treatments. Dermatol Res Pract (2010) 0.87
Phenotypic overlap between MMP-13 and the plasminogen activation system during wound healing in mice. PLoS One (2011) 0.86
The reinnervation pattern of wounds and scars after treatment with transforming growth factor β isoforms. J Plast Reconstr Aesthet Surg (2012) 0.86
Temporal and spatial expression of Pax9 and Sonic hedgehog during development of normal mouse palates and cleft palates in TGF-beta3 null embryos. Arch Oral Biol (2006) 0.86
Concomitant lack of MMP9 and uPA disturbs physiological tissue remodeling. Dev Biol (2011) 0.86
Quantification of total and perfused blood vessels in murine skin autografts using a fluorescent double-labeling technique. Plast Reconstr Surg (2006) 0.85
Interleukin-10 reduces scarring and enhances regeneration at a site of sciatic nerve repair. J Peripher Nerv Syst (2007) 0.85
GPI-specific phospholipase D mRNA expression in tumor cells of different malignancy. Clin Exp Metastasis (2002) 0.85
Repigmentation of cutaneous scars depends on original wound type. J Anat (2013) 0.84
Scar redness in humans: how long does it persist after incisional and excisional wounding? Plast Reconstr Surg (2008) 0.84
Functional corpora lutea are formed in matrix metalloproteinase inhibitor-treated plasminogen-deficient mice. Endocrinology (2006) 0.84
The microcirculation in acute murine cutaneous incisional wounds shows a spatial and temporal variation in the functionality of vessels. Wound Repair Regen (2006) 0.83
Variable impairment of wound healing in the heterozygous collagenase-resistant mouse. Wound Repair Regen (2005) 0.83
Bone marrow-derived endothelial progenitor cells do not contribute significantly to new vessels during incisional wound healing. Exp Hematol (2007) 0.83
Glycoconjugate profiling of primary melanoma and its sentinel node and distant metastases: implications for diagnosis and pathophysiology of metastases. Cancer Lett (2006) 0.83
Neutralisation of uPA with a monoclonal antibody reduces plasmin formation and delays skin wound healing in tPA-deficient mice. PLoS One (2010) 0.82
Avotermin: a novel antiscarring agent. Int J Low Extrem Wounds (2008) 0.82
Therapies with emerging evidence of efficacy: avotermin for the improvement of scarring. Dermatol Res Pract (2010) 0.82
Animal models for adult dermal wound healing. Methods Mol Med (2005) 0.82
Wound healing: a model of dermal wound repair. Methods Mol Biol (2003) 0.82
Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration. Blood (2010) 0.81
Denervation affects regenerative responses in MRL/MpJ and repair in C57BL/6 ear wounds. J Anat (2011) 0.81
MMP9 is protective against lethal inflammatory mass lesions in the mouse colon. Dis Model Mech (2010) 0.81
Does plasminogen activator inhibitor-1 drive lymphangiogenesis? PLoS One (2010) 0.80
Avotermin for the improvement of scar appearance: a new pharmaceutical in a new therapeutic area. Expert Opin Investig Drugs (2009) 0.80