Published in Autoimmunity on December 01, 2003
A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus. Immunity (2008) 5.89
Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response. Nat Genet (2009) 5.84
Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase. J Biol Chem (2011) 3.21
Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type I and type II interferon signatures. Arthritis Rheumatol (2014) 2.58
Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance. Immunol Rev (2010) 2.55
Interferon regulatory factors in human lupus pathogenesis. Transl Res (2011) 1.81
Network analysis of associations between serum interferon-α activity, autoantibodies, and clinical features in systemic lupus erythematosus. Arthritis Rheum (2011) 1.79
An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity. Mol Med (2007) 1.79
Interferon alpha as a primary pathogenic factor in human lupus. J Interferon Cytokine Res (2011) 1.69
Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model. J Exp Med (2014) 1.59
Genetic regulation of serum cytokines in systemic lupus erythematosus. Transl Res (2009) 1.49
The impact of vitamin D on dendritic cell function in patients with systemic lupus erythematosus. PLoS One (2010) 1.42
Recent advances in the genetics of systemic lupus erythematosus. Expert Rev Clin Immunol (2010) 1.35
Type I interferon in organ-targeted autoimmune and inflammatory diseases. Arthritis Res Ther (2010) 1.32
A loss-of-function variant of the antiviral molecule MAVS is associated with a subset of systemic lupus patients. EMBO Mol Med (2011) 1.29
Type I interferon in the pathogenesis of lupus. J Immunol (2014) 1.29
A critical role for type I IFN in arthritis development following Borrelia burgdorferi infection of mice. J Immunol (2008) 1.23
Development of Potential Pharmacodynamic and Diagnostic Markers for Anti-IFN-α Monoclonal Antibody Trials in Systemic Lupus Erythematosus. Hum Genomics Proteomics (2009) 1.22
Microarray-based identification of novel biomarkers in IL-1-mediated diseases. Curr Opin Immunol (2007) 1.21
Cytokines and cytokine profiles in human autoimmune diseases and animal models of autoimmunity. Mediators Inflamm (2009) 1.17
Poly(I:C) drives type I IFN- and TGFβ-mediated inflammation and dermal fibrosis simulating altered gene expression in systemic sclerosis. J Invest Dermatol (2010) 1.17
How the study of children with rheumatic diseases identified interferon-alpha and interleukin-1 as novel therapeutic targets. Immunol Rev (2008) 1.15
New tools for classification and monitoring of autoimmune diseases. Nat Rev Rheumatol (2012) 1.13
High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups. Arthritis Rheum (2009) 1.11
Interferon-alpha: a therapeutic target in systemic lupus erythematosus. Rheum Dis Clin North Am (2010) 1.08
Plasmacytoid dendritic cells protect against atherosclerosis by tuning T-cell proliferation and activity. Circ Res (2011) 1.08
MxA gene expression in juvenile dermatomyositis peripheral blood mononuclear cells: association with muscle involvement. Clin Immunol (2006) 1.08
Overview of the biology of type I interferons. Arthritis Res Ther (2010) 1.07
Toll-like receptors and innate immune responses in systemic lupus erythematosus. Arthritis Res Ther (2007) 1.07
Transcriptional signatures as a disease-specific and predictive inflammatory biomarker for type 1 diabetes. Genes Immun (2012) 1.04
Type I interferons produced by resident renal cells may promote end-organ disease in autoantibody-mediated glomerulonephritis. J Immunol (2009) 1.04
Cytokines in systemic lupus erythematosus. Curr Mol Med (2009) 1.03
Amyloid-DNA Composites of Bacterial Biofilms Stimulate Autoimmunity. Immunity (2015) 1.00
The interferon signature and STAT1 expression in rheumatoid arthritis synovial fluid macrophages are induced by tumor necrosis factor α and counter-regulated by the synovial fluid microenvironment. Arthritis Rheum (2012) 1.00
Lupus nephritis: an overview of recent findings. Autoimmune Dis (2012) 1.00
IFN-α mediates the development of autoimmunity both by direct tissue toxicity and through immune cell recruitment mechanisms. J Immunol (2011) 0.98
Treatment of neuromyelitis optica: current debate. Ther Adv Neurol Disord (2008) 0.95
The dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunity. Front Immunol (2013) 0.94
dsRNA sensors and plasmacytoid dendritic cells in host defense and autoimmunity. Immunol Rev (2011) 0.93
Advances in understanding the role of type I interferons in systemic lupus erythematosus. Curr Opin Rheumatol (2014) 0.93
An integrated peptide-antigen microarray on plasmonic gold films for sensitive human antibody profiling. PLoS One (2013) 0.92
Gene expression profiling provides insights into the pathways involved in inflammatory arthritis development: murine model of Lyme disease. Exp Mol Pathol (2008) 0.92
Identification of molecular biomarkers for multiple sclerosis. J Mol Diagn (2007) 0.92
Accumulation of plasmacytoid DC: Roles in disease pathogenesis and targets for immunotherapy. Eur J Immunol (2010) 0.92
Targeting of type I interferon in systemic autoimmune diseases. Transl Res (2014) 0.92
Protein synthesis of the pro-inflammatory S100A8/A9 complex in plasmacytoid dendritic cells and cell surface S100A8/A9 on leukocyte subpopulations in systemic lupus erythematosus. Arthritis Res Ther (2011) 0.92
TH17 deficiency in human disease. J Allergy Clin Immunol (2012) 0.92
The role of cytokines in the pathogenesis and treatment of systemic lupus erythematosus. J Interferon Cytokine Res (2011) 0.91
Myeloid dendritic cells from B6.NZM Sle1/Sle2/Sle3 lupus-prone mice express an IFN signature that precedes disease onset. J Immunol (2012) 0.91
The type I interferons: Basic concepts and clinical relevance in immune-mediated inflammatory diseases. Gene (2015) 0.87
Cytokine regulation of B-cell migratory behavior favors formation of germinal centers in autoimmune disease. Discov Med (2011) 0.86
Developments in the clinical understanding of lupus. Arthritis Res Ther (2009) 0.86
Interferon-induced protein IFIT4 is associated with systemic lupus erythematosus and promotes differentiation of monocytes into dendritic cell-like cells. Arthritis Res Ther (2008) 0.85
Modulation of p38 MAPK activity in regulatory T cells after tolerance with anti-DNA Ig peptide in (NZB x NZW)F1 lupus mice. J Immunol (2009) 0.85
The genetics of systemic lupus erythematosus: understanding how SNPs confer disease susceptibility. Springer Semin Immunopathol (2006) 0.84
Bioinformatics analysis of the factors controlling type I IFN gene expression in autoimmune disease and virus-induced immunity. Front Immunol (2013) 0.82
Sex differences in murine susceptibility to systemic viral infections. J Autoimmun (2011) 0.82
Using gene expression to improve the power of genome-wide association analysis. Hum Hered (2014) 0.82
Reduced levels of CCL2 and CXCL10 in systemic lupus erythematosus patients under treatment with prednisone, mycophenolate mofetil, or hydroxychloroquine, except in a high STAT1 subset. Arthritis Res Ther (2014) 0.81
Elevated signal transducers and activators of transcription 1 correlates with increased C-C motif chemokine ligand 2 and C-X-C motif chemokine 10 levels in peripheral blood of patients with systemic lupus erythematosus. Arthritis Res Ther (2014) 0.81
Interferon-induced versus chemokine transcripts as lupus biomarkers. Arthritis Res Ther (2008) 0.81
Estradiol targets T cell signaling pathways in human systemic lupus. Clin Immunol (2009) 0.80
Expression of an anti-RNA autoantibody in a mouse model of SLE increases neutrophil and monocyte numbers as well as IFN-I expression. Eur J Immunol (2013) 0.79
Blood gene expression profiling in pediatric systemic lupus erythematosus and systemic juvenile idiopathic arthritis: from bench to bedside. Pediatr Rheumatol Online J (2014) 0.79
Identification of specific chondroitin sulfate species in cutaneous autoimmune disease. J Histochem Cytochem (2011) 0.79
Microarray profiling of lymphocytes in internal diseases with an altered immune response: potential and methodology. Mediators Inflamm (2005) 0.79
Functional genomics of endothelial cells treated with anti-angiogenic or angiopreventive drugs. Clin Exp Metastasis (2010) 0.79
Positive correlation of STAT1 and miR-146a with anemia in patients with systemic lupus erythematosus. J Clin Immunol (2013) 0.78
Biomarkers as tools for improved diagnostic and therapeutic monitoring in systemic lupus erythematosis. Arthritis Res Ther (2009) 0.78
Type I IFN Is Necessary and Sufficient for Inflammation-Induced Red Blood Cell Alloimmunization in Mice. J Immunol (2017) 0.77
Suppression of IRAK1 or IRAK4 Catalytic Activity, but Not Type 1 IFN Signaling, Prevents Lupus Nephritis in Mice Expressing a Ubiquitin Binding-Defective Mutant of ABIN1. J Immunol (2016) 0.77
Genomic-based high throughput screening identifies small molecules that differentially inhibit the antiviral and immunomodulatory effects of IFN-alpha. Mol Med (2008) 0.77
Transcriptomic Segregation of Human Autoantigens Useful for the Diagnosis of Autoimmune Diseases. Mol Diagn Ther (2016) 0.77
Borrelia burgdorferi arthritis-associated locus Bbaa1 regulates Lyme arthritis and K/B×N serum transfer arthritis through intrinsic control of type I IFN production. J Immunol (2014) 0.77
Interleukin 6 Accelerates Mortality by Promoting the Progression of the Systemic Lupus Erythematosus-Like Disease of BXSB.Yaa Mice. PLoS One (2016) 0.77
Network Analysis Identifies Proinflammatory Plasma Cell Polarization for Secretion of ISG15 in Human Autoimmunity. J Immunol (2016) 0.76
Identification of Candidate Predictors of Lupus Flare. Trans Am Clin Climatol Assoc (2015) 0.76
TLR ligands up-regulate Trex1 expression in murine conventional dendritic cells through type I Interferon and NF-κB-dependent signaling pathways. J Leukoc Biol (2014) 0.76
Genome-Wide DNA Methylation Analysis of Chinese Patients with Systemic Lupus Erythematosus Identified Hypomethylation in Genes Related to the Type I Interferon Pathway. PLoS One (2017) 0.76
Pathways leading to an immunological disease: systemic lupus erythematosus. Rheumatology (Oxford) (2017) 0.75
Spotlight on blisibimod and its potential in the treatment of systemic lupus erythematosus: evidence to date. Drug Des Devel Ther (2017) 0.75
Crosstalk Between Apoptosis and Autophagy: Environmental Genotoxins, Infection, and Innate Immunity. J Cell Death (2017) 0.75
Human SLE bone marrow mesenchymal stem cells (BMSCs) have a senescence-associated secretory phenotype (SASP) mediated by a MAVS-IFNβ feedback loop. Arthritis Rheumatol (2017) 0.75
Lipoprotein(a) concentrations, rosuvastatin therapy, and residual vascular risk: an analysis from the JUPITER Trial (Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin). Circulation (2013) 3.02
Cutting edge: autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-alpha in lupus patients in vivo. J Immunol (2009) 2.39
Relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis patients. Arthritis Rheum (2010) 1.77
Microarray analysis of gene expression in lupus. Arthritis Res Ther (2003) 1.67
Interferon-alpha in systemic lupus erythematosus. Curr Opin Rheumatol (2004) 1.60
Felty's syndrome autoantibodies bind to deiminated histones and neutrophil extracellular chromatin traps. Arthritis Rheum (2011) 1.38
Safety profile and clinical activity of sifalimumab, a fully human anti-interferon α monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study. Ann Rheum Dis (2011) 1.37
Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-α and serologic autoimmunity in lupus patients. J Immunol (2011) 1.34
Nodular endocardial infiltrates (Quilty lesions) cause significant variability in diagnosis of ISHLT Grade 2 and 3A rejection in cardiac allograft recipients. J Heart Lung Transplant (2005) 1.20
Imatinib mesylate (Gleevec) in the treatment of diffuse cutaneous systemic sclerosis: results of a 1-year, phase IIa, single-arm, open-label clinical trial. Ann Rheum Dis (2011) 1.20
Elevated levels of soluble CD40 ligand (sCD40L) in serum of patients with systemic autoimmune diseases. J Autoimmun (2006) 1.07
Measurement of cell-bound complement activation products enhances diagnostic performance in systemic lupus erythematosus. Arthritis Rheum (2012) 0.98
Cytokine-mediated regulation of activating and inhibitory Fc gamma receptors in human monocytes. J Leukoc Biol (2005) 0.97
T cell proliferation induced by autologous non-T cells is a response to apoptotic cells processed by dendritic cells. J Immunol (2002) 0.94
Enhanced rho-associated protein kinase activation in patients with systemic lupus erythematosus. Arthritis Rheum (2013) 0.91
Increased serum type I interferon activity in organ-specific autoimmune disorders: clinical, imaging, and serological associations. Front Immunol (2013) 0.85
Distinct inflammatory gene pathways induced by particles. Clin Orthop Relat Res (2007) 0.84
Interferon-induced versus chemokine transcripts as lupus biomarkers. Arthritis Res Ther (2008) 0.81
Belimumab in systemic lupus erythematosus: an update for clinicians. Ther Adv Chronic Dis (2012) 0.80
A new tool for detection of type I interferon activation in systemic lupus erythematosus. Arthritis Res Ther (2010) 0.78
Measuring interferon alpha and other cytokines in SLE. Methods Mol Biol (2014) 0.78
Type I interferons as biomarkers in autoimmune diseases. Biomark Med (2012) 0.77
Antiinflammatory strategies, not just B cell depletion, are required for optimal therapy for severe proliferative lupus nephritis: comment on the article by Rovin et al. Arthritis Rheum (2012) 0.76
Identification of Candidate Predictors of Lupus Flare. Trans Am Clin Climatol Assoc (2015) 0.76
A 26-year-old white man with a systemic lupus erythematosus flare and acute multiorgan ischemia: Vasculitis or thrombosis? Arthritis Care Res (Hoboken) (2011) 0.75
Two systemic lupus erythematosus patients with severe pleurisy: similar presentations, different causes. Arthritis Care Res (Hoboken) (2013) 0.75