Published in J Cell Sci on March 02, 2004
Endocrine-disrupting chemicals: an Endocrine Society scientific statement. Endocr Rev (2009) 9.60
The tissue organization field theory of cancer: a testable replacement for the somatic mutation theory. Bioessays (2011) 5.01
No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas. Nat Genet (2008) 3.32
Breast cancer: origins and evolution. J Clin Invest (2007) 3.31
Modeling dynamic reciprocity: engineering three-dimensional culture models of breast architecture, function, and neoplastic transformation. Semin Cancer Biol (2005) 2.53
Prenatal bisphenol A exposure induces preneoplastic lesions in the mammary gland in Wistar rats. Environ Health Perspect (2007) 2.29
Microenvironmental regulation of cancer development. Curr Opin Genet Dev (2008) 2.25
Can cancer be reversed by engineering the tumor microenvironment? Semin Cancer Biol (2008) 2.07
Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts. Am J Pathol (2005) 2.02
A system for studying epithelial-stromal interactions reveals distinct inductive abilities of stromal cells from benign prostatic hyperplasia and prostate cancer. Endocrinology (2004) 1.99
Induction of mammary gland ductal hyperplasias and carcinoma in situ following fetal bisphenol A exposure. Reprod Toxicol (2006) 1.92
A cancer theory kerfuffle can lead to new lines of research. J Natl Cancer Inst (2014) 1.91
Bone marrow mesenchymal stem cells are abnormal in multiple myeloma. Leukemia (2007) 1.86
Environmental causes of cancer: endocrine disruptors as carcinogens. Nat Rev Endocrinol (2010) 1.85
Remodeling of the mammary microenvironment after lactation promotes breast tumor cell metastasis. Am J Pathol (2006) 1.83
Breast cancer by proxy: can the microenvironment be both the cause and consequence? Trends Mol Med (2008) 1.60
Research on early-stage carcinogenesis: are we approaching paradigm instability? J Clin Oncol (2010) 1.58
Transforming growth factor-beta in breast cancer: too much, too late. Breast Cancer Res (2009) 1.51
Theories of carcinogenesis: an emerging perspective. Semin Cancer Biol (2008) 1.49
Stromal regulation of neoplastic development: age-dependent normalization of neoplastic mammary cells by mammary stroma. Am J Pathol (2005) 1.48
Does breast cancer start in the womb? Basic Clin Pharmacol Toxicol (2008) 1.45
Why the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkers. Cell Adh Migr (2012) 1.41
The breast cancer and the environment research centers: transdisciplinary research on the role of the environment in breast cancer etiology. Environ Health Perspect (2009) 1.38
Nonlinear optical imaging to evaluate the impact of obesity on mammary gland and tumor stroma. Mol Imaging (2007) 1.36
Targeting stroma to treat cancers. Semin Cancer Biol (2011) 1.33
Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of Cystatin M in epithelial cells. Cancer Res (2008) 1.30
Stromagenesis during tumorigenesis: characterization of tumor-associated fibroblasts and stroma-derived 3D matrices. Methods Mol Biol (2009) 1.27
Toward a genetics of cancer resistance. Proc Natl Acad Sci U S A (2009) 1.25
Morphogenetic fields in embryogenesis, regeneration, and cancer: non-local control of complex patterning. Biosystems (2012) 1.23
Bisphenol A alters the development of the rhesus monkey mammary gland. Proc Natl Acad Sci U S A (2012) 1.21
Does cancer start in the womb? altered mammary gland development and predisposition to breast cancer due to in utero exposure to endocrine disruptors. J Mammary Gland Biol Neoplasia (2013) 1.20
Arousal of cancer-associated stroma: overexpression of palladin activates fibroblasts to promote tumor invasion. PLoS One (2012) 1.20
New highlights on stroma-epithelial interactions in breast cancer. Breast Cancer Res (2004) 1.19
Watch thy neighbor: cancer is a communal affair. J Cell Sci (2004) 1.17
The microenvironment determines the breast cancer cells' phenotype: organization of MCF7 cells in 3D cultures. BMC Cancer (2010) 1.16
Plausibility of stromal initiation of epithelial cancers without a mutation in the epithelium: a computer simulation of morphostats. BMC Cancer (2009) 1.15
Transforming growth factor-beta signaling-deficient fibroblasts enhance hepatocyte growth factor signaling in mammary carcinoma cells to promote scattering and invasion. Mol Cancer Res (2008) 1.15
Perinatally administered bisphenol a as a potential mammary gland carcinogen in rats. Environ Health Perspect (2013) 1.13
Paradoxes in carcinogenesis: new opportunities for research directions. BMC Cancer (2007) 1.10
The aging of the 2000 and 2011 Hallmarks of Cancer reviews: a critique. J Biosci (2013) 1.08
Ovarian normal and tumor-associated fibroblasts retain in vivo stromal characteristics in a 3-D matrix-dependent manner. Gynecol Oncol (2008) 1.07
Endocrine disruptors and the breast: early life effects and later life disease. J Mammary Gland Biol Neoplasia (2013) 1.07
A complex 3D human tissue culture system based on mammary stromal cells and silk scaffolds for modeling breast morphogenesis and function. Biomaterials (2010) 1.07
Hormone-induced protection of mammary tumorigenesis in genetically engineered mouse models. Breast Cancer Res (2007) 1.06
Vascular endothelial growth factor secreted by activated stroma enhances angiogenesis and hormone-independent growth of estrogen receptor-positive breast cancer. Cancer Res (2010) 1.05
Mutations in bone marrow-derived stromal stem cells unmask latent malignancy. Stem Cells Dev (2010) 1.05
An integrative view on sex differences in brain tumors. Cell Mol Life Sci (2015) 1.04
Anti-HDGF targets cancer and cancer stromal stem cells resistant to chemotherapy. Clin Cancer Res (2013) 1.04
The assessment of angiogenesis and fibroblastic stromagenesis in hyperplastic and pre-invasive breast lesions. BMC Cancer (2008) 1.00
Altered expression of fibronectin and collagens I and IV in multiple myeloma and monoclonal gammopathy of undetermined significance. J Histochem Cytochem (2008) 0.98
Relevance of the stroma and epithelial-mesenchymal transition (EMT) for the rheumatic diseases. Arthritis Res Ther (2006) 0.97
Estrogen and progesterone induce persistent increases in p53-dependent apoptosis and suppress mammary tumors in BALB/c-Trp53+/- mice. Breast Cancer Res (2008) 0.97
Hedgehog signaling in myofibroblasts directly promotes prostate tumor cell growth. Integr Biol (Camb) (2012) 0.97
A review of the carcinogenic potential of bisphenol A. Reprod Toxicol (2015) 0.92
Radiation carcinogenesis in context: how do irradiated tissues become tumors? Health Phys (2009) 0.92
Tumor and the microenvironment: a chance to reframe the paradigm of carcinogenesis? Biomed Res Int (2014) 0.91
Is information a proper observable for biological organization? Prog Biophys Mol Biol (2012) 0.91
Association of estrogen receptor-alpha and progesterone receptor A expression with hormonal mammary carcinogenesis: role of the host microenvironment. Breast Cancer Res (2007) 0.91
Carcinoma-associated fibroblasts: orchestrating the composition of malignancy. Genes Dev (2016) 0.91
Estrogens in the wrong place at the wrong time: Fetal BPA exposure and mammary cancer. Reprod Toxicol (2014) 0.90
Breast cancer, stem cells and prospects for therapy. Breast Cancer Res (2006) 0.90
Endogenous Voltage Potentials and the Microenvironment: Bioelectric Signals that Reveal, Induce and Normalize Cancer. J Clin Exp Oncol (2013) 0.90
Is systems biology a promising approach to resolve controversies in cancer research? Cancer Cell Int (2012) 0.89
The inflammatory network: bridging senescent stroma and epithelial tumorigenesis. Front Biosci (Landmark Ed) (2009) 0.89
Optimizing a 3D Culture System to Study the Interaction between Epithelial Breast Cancer and Its Surrounding Fibroblasts. J Cancer (2011) 0.88
Preadipocytes stimulate ductal morphogenesis and functional differentiation of human mammary epithelial cells on 3D silk scaffolds. Tissue Eng Part A (2009) 0.88
Hormonal regulation of epithelial organization in a three-dimensional breast tissue culture model. Tissue Eng Part C Methods (2013) 0.86
Competing views on cancer. J Biosci (2014) 0.86
Seed in soil, with an epigenetic view. Biochim Biophys Acta (2008) 0.86
Interlobular and intralobular mammary stroma: genotype may not reflect phenotype. BMC Cell Biol (2008) 0.85
Immunohistochemical expression of epithelial and stromal immunomodulatory signalling molecules is a prognostic indicator in breast cancer. BMC Res Notes (2012) 0.85
Environmental endocrine disruptors: Effects on the human male reproductive system. Rev Endocr Metab Disord (2015) 0.83
Stromal dynamic reciprocity in cancer: intricacies of fibroblastic-ECM interactions. Curr Opin Cell Biol (2016) 0.83
Chemopreventive doses of methylselenocysteine alter circadian rhythm in rat mammary tissue. Cancer Prev Res (Phila) (2008) 0.82
Dual regulation of breast tubulogenesis using extracellular matrix composition and stromal cells. Tissue Eng Part A (2011) 0.82
Breast cancer cells promote a notch-dependent mesenchymal phenotype in endothelial cells participating to a pro-tumoral niche. J Transl Med (2015) 0.81
Microenvironment promotes tumor cell reprogramming in human breast cancer cell lines. PLoS One (2013) 0.81
The biological sense of cancer: a hypothesis. Theor Biol Med Model (2006) 0.81
Stromal mediation of radiation carcinogenesis. J Mammary Gland Biol Neoplasia (2010) 0.80
Microenvironmental control of the breast cancer cell cycle. Anat Rec (Hoboken) (2012) 0.80
Raising gestational choline intake alters gene expression in DMBA-evoked mammary tumors and prolongs survival. FASEB J (2008) 0.80
High Expression of Cyclin D1 and p21 in N-Nitroso-N-Methylurea-Induced Breast Cancer in Wistar Albino Female Rats. Cell J (2012) 0.79
Interpreting endocrine disruption from an integrative biology perspective. Mol Cell Endocrinol (2009) 0.79
Lack of c-kit receptor promotes mammary tumors in N-nitrosomethylurea-treated Ws/Ws rats. Cancer Cell Int (2008) 0.79
Histological analysis of low dose NMU effects in the rat mammary gland. BMC Cancer (2009) 0.79
Cancer Metastases: So Close and So Far. J Natl Cancer Inst (2015) 0.79
Soiling the seed: microenvironment and epithelial mesenchymal plasticity. Cancer Microenviron (2012) 0.78
Augmented expression of urokinase plasminogen activator and extracellular matrix proteins associates with multiple myeloma progression. Clin Exp Metastasis (2014) 0.78
Targeted gene silencing using a follicle-stimulating hormone peptide-conjugated nanoparticle system improves its specificity and efficacy in ovarian clear cell carcinoma in vitro. J Ovarian Res (2013) 0.78
Epithelial cancers in the post-genomic era: should we reconsider our lifestyle? Cancer Metastasis Rev (2013) 0.78
The role of mutation in the new cancer paradigm. Cancer Cell Int (2005) 0.78
3D bioprinting: improving in vitro models of metastasis with heterogeneous tumor microenvironments. Dis Model Mech (2017) 0.78
Cancer: evolutionary, genetic and epigenetic aspects. Clin Epigenetics (2010) 0.77
Mesenchymal Stem and Progenitor Cells in Normal and Dysplastic Hematopoiesis-Masters of Survival and Clonality? Int J Mol Sci (2016) 0.76
A novel pathogenic classification of cancers. Cancer Cell Int (2014) 0.76
Carcinogenesis explained within the context of a theory of organisms. Prog Biophys Mol Biol (2016) 0.76
Hormone-responsive 3D multicellular culture model of human breast tissue. Biomaterials (2012) 0.76
Carcinogenesis and metastasis now in the third dimension--what's in it for pathologists? Am J Pathol (2006) 0.76
Endocrine-disrupting chemicals: an Endocrine Society scientific statement. Endocr Rev (2009) 9.60
Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr Rev (2012) 6.12
The tissue organization field theory of cancer: a testable replacement for the somatic mutation theory. Bioessays (2011) 5.01
Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure. Reprod Toxicol (2007) 4.04
Bisphenol-A and the great divide: a review of controversies in the field of endocrine disruption. Endocr Rev (2008) 4.03
In vitro molecular mechanisms of bisphenol A action. Reprod Toxicol (2007) 3.69
Why public health agencies cannot depend on good laboratory practices as a criterion for selecting data: the case of bisphenol A. Environ Health Perspect (2008) 3.27
The somatic mutation theory of cancer: growing problems with the paradigm? Bioessays (2004) 2.91
Evidence of altered brain sexual differentiation in mice exposed perinatally to low, environmentally relevant levels of bisphenol A. Endocrinology (2006) 2.63
Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice. Immunity (2006) 2.36
Prenatal bisphenol A exposure induces preneoplastic lesions in the mammary gland in Wistar rats. Environ Health Perspect (2007) 2.29
Endocrine disruptors and reproductive health: the case of bisphenol-A. Mol Cell Endocrinol (2006) 2.22
Perinatal exposure to bisphenol-A alters peripubertal mammary gland development in mice. Endocrinology (2005) 2.14
Induction of mammary gland ductal hyperplasias and carcinoma in situ following fetal bisphenol A exposure. Reprod Toxicol (2006) 1.92
Exposure to environmentally relevant doses of the xenoestrogen bisphenol-A alters development of the fetal mouse mammary gland. Endocrinology (2006) 1.90
Environmental causes of cancer: endocrine disruptors as carcinogens. Nat Rev Endocrinol (2010) 1.85
An evaluation of evidence for the carcinogenic activity of bisphenol A. Reprod Toxicol (2007) 1.83
Bisphenol A: Perinatal exposure and body weight. Mol Cell Endocrinol (2009) 1.82
Long-term effects of fetal exposure to low doses of the xenoestrogen bisphenol-A in the female mouse genital tract. Biol Reprod (2005) 1.79
Biotransformations of bisphenol A in a mammalian model: answers and new questions raised by low-dose metabolic fate studies in pregnant CD1 mice. Environ Health Perspect (2003) 1.62
Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing. Fertil Steril (2008) 1.60
Perinatal exposure to the xenoestrogen bisphenol-A induces mammary intraductal hyperplasias in adult CD-1 mice. Reprod Toxicol (2008) 1.53
Theories of carcinogenesis: an emerging perspective. Semin Cancer Biol (2008) 1.49
Stromal regulation of neoplastic development: age-dependent normalization of neoplastic mammary cells by mammary stroma. Am J Pathol (2005) 1.48
A novel 3D in vitro culture model to study stromal-epithelial interactions in the mammary gland. Tissue Eng Part C Methods (2008) 1.45
Does breast cancer start in the womb? Basic Clin Pharmacol Toxicol (2008) 1.45
Mammalian development in a changing environment: exposure to endocrine disruptors reveals the developmental plasticity of steroid-hormone target organs. Evol Dev (2002) 1.43
Science and policy on endocrine disrupters must not be mixed: a reply to a "common sense" intervention by toxicology journal editors. Environ Health (2013) 1.42
Perinatal exposure to environmentally relevant levels of bisphenol A decreases fertility and fecundity in CD-1 mice. Environ Health Perspect (2010) 1.41
Endocrine disruptors: from Wingspread to environmental developmental biology. J Steroid Biochem Mol Biol (2002) 1.33
Perinatal bisphenol A exposure increases estrogen sensitivity of the mammary gland in diverse mouse strains. Environ Health Perspect (2007) 1.28
The mammary gland response to estradiol: monotonic at the cellular level, non-monotonic at the tissue-level of organization? J Steroid Biochem Mol Biol (2006) 1.23
Bisphenol A alters the development of the rhesus monkey mammary gland. Proc Natl Acad Sci U S A (2012) 1.21
Does cancer start in the womb? altered mammary gland development and predisposition to breast cancer due to in utero exposure to endocrine disruptors. J Mammary Gland Biol Neoplasia (2013) 1.20
Importance of dosage standardization for interpreting transcriptomal signature profiles: evidence from studies of xenoestrogens. Proc Natl Acad Sci U S A (2006) 1.16
The microenvironment determines the breast cancer cells' phenotype: organization of MCF7 cells in 3D cultures. BMC Cancer (2010) 1.16
Plausibility of stromal initiation of epithelial cancers without a mutation in the epithelium: a computer simulation of morphostats. BMC Cancer (2009) 1.15
Endocrine-disrupting effects of cattle feedlot effluent on an aquatic sentinel species, the fathead minnow. Environ Health Perspect (2004) 1.14
Perinatally administered bisphenol a as a potential mammary gland carcinogen in rats. Environ Health Perspect (2013) 1.13
Emergentism as a default: cancer as a problem of tissue organization. J Biosci (2005) 1.12
Hormone replacement therapy, cancer, controversies, and women's health: historical, epidemiological, biological, clinical, and advocacy perspectives. J Epidemiol Community Health (2005) 1.11
Low-dose BPA exposure alters the mesenchymal and epithelial transcriptomes of the mouse fetal mammary gland. PLoS One (2013) 1.11
The aging of the 2000 and 2011 Hallmarks of Cancer reviews: a critique. J Biosci (2013) 1.08
The death of the cancer cell. Cancer Res (2011) 1.07
Regulatory decisions on endocrine disrupting chemicals should be based on the principles of endocrinology. Reprod Toxicol (2013) 1.07
A complex 3D human tissue culture system based on mammary stromal cells and silk scaffolds for modeling breast morphogenesis and function. Biomaterials (2010) 1.07
Strengths and weaknesses of in vitro assays for estrogenic and androgenic activity. Best Pract Res Clin Endocrinol Metab (2006) 1.06
Estrogenic activity of polychlorinated biphenyls present in human tissue and the environment. Environ Sci Technol (2006) 1.06
The role of collagen reorganization on mammary epithelial morphogenesis in a 3D culture model. Biomaterials (2010) 1.05
Androgenic and estrogenic activity in water bodies receiving cattle feedlot effluent in Eastern Nebraska, USA. Environ Health Perspect (2004) 1.02
Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research. Toxicol Sci (2010) 0.99
Effects of low doses of bisphenol A on the metabolome of perinatally exposed CD-1 mice. Environ Health Perspect (2013) 0.96
Skin biopsy: a useful tool in the diagnosis of lysosomal storage diseases. Ultrastruct Pathol (2006) 0.96
The effect of stromal components on the modulation of the phenotype of human bronchial epithelial cells in 3D culture. Biomaterials (2011) 0.95
Neoplasia as development gone awry: the role of endocrine disruptors. Int J Androl (2007) 0.90
Is systems biology a promising approach to resolve controversies in cancer research? Cancer Cell Int (2012) 0.89
Preadipocytes stimulate ductal morphogenesis and functional differentiation of human mammary epithelial cells on 3D silk scaffolds. Tissue Eng Part A (2009) 0.88
Interlaboratory comparison of four in vitro assays for assessing androgenic and antiandrogenic activity of environmental chemicals. Environ Health Perspect (2004) 0.87
Clinical, biochemical, and molecular diagnosis of a free sialic acid storage disease patient of moderate severity. Mol Genet Metab (2004) 0.87
Competing views on cancer. J Biosci (2014) 0.86
Hormonal regulation of epithelial organization in a three-dimensional breast tissue culture model. Tissue Eng Part C Methods (2013) 0.86
In search of principles for a Theory of Organisms. J Biosci (2015) 0.83
Dual regulation of breast tubulogenesis using extracellular matrix composition and stromal cells. Tissue Eng Part A (2011) 0.82
Mechanism of androgen action on cell proliferation: AS3 protein as a mediator of proliferative arrest in the rat prostate. Endocrinology (2002) 0.81
APRIN is a unique Pds5 paralog with features of a chromatin regulator in hormonal differentiation. J Steroid Biochem Mol Biol (2007) 0.81