High Expression of Cyclin D1 and p21 in N-Nitroso-N-Methylurea-Induced Breast Cancer in Wistar Albino Female Rats.

PubWeight™: 0.79‹?›

🔗 View Article (PMC 3584436)

Published in Cell J on December 12, 2012

Authors

Mahboobeh Ashrafi1, Seyedeh Zahra Bathaie, Saeid Abroun

Author Affiliations

1: 1. Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University (TUM), Tehran, Iran.

Articles cited by this

The stroma as a crucial target in rat mammary gland carcinogenesis. J Cell Sci (2004) 3.83

Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle. Curr Opin Cell Biol (2000) 3.22

Murine mammary gland carcinogenesis is critically dependent on progesterone receptor function. Cancer Res (1999) 1.87

Host factors affecting the growth of carcinogen-induced rat mammary carcinomas: a review and tribute to Charles Brenton Huggins. Cancer Res (1985) 1.81

Cyclin D1 and breast cancer. Breast (2006) 1.71

Rapid induction of mammary intraductal proliferations, ductal carcinoma in situ and carcinomas by the injection of sexually immature female rats with 1-methyl-1-nitrosourea. Carcinogenesis (1995) 1.59

Gene expression profiling of NMU-induced rat mammary tumors: cross species comparison with human breast cancer. Carcinogenesis (2005) 1.46

Mixed tocopherols prevent mammary tumorigenesis by inhibiting estrogen action and activating PPAR-gamma. Clin Cancer Res (2009) 1.33

Hormone-induced protection against mammary tumorigenesis is conserved in multiple rat strains and identifies a core gene expression signature induced by pregnancy. Cancer Res (2006) 1.30

Dose-responsive induction of mammary gland carcinomas by the intraperitoneal injection of 1-methyl-1-nitrosourea. Cancer Res (1991) 1.28

Rat models of premalignant breast disease. J Mammary Gland Biol Neoplasia (2000) 1.20

Estrogen receptor activation at serine 305 is sufficient to upregulate cyclin D1 in breast cancer cells. FEBS Lett (2004) 1.12

Selenium modulation of cell proliferation and cell cycle biomarkers in normal and premalignant cells of the rat mammary gland. Cancer Epidemiol Biomarkers Prev (2000) 1.01

Deregulated expression of cyclin D1 and other cell cycle-related genes in carcinogen-induced rat mammary tumors. Carcinogenesis (1995) 1.00

Ethanol reduces p38 kinase activation and cyclin D1 protein expression after partial hepatectomy in rats. J Hepatol (2005) 0.99

Pathology of tumours in laboratory animals. Tumours of the rat. Tumours of the mammary gland. IARC Sci Publ (1990) 0.97

An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells. Breast Cancer Res (2007) 0.94

Pharmacodynamics of tamoxifen and its 4-hydroxy and N-desmethyl metabolites: activation of caspases and induction of apoptosis in rat mammary tumors and in human breast cancer cell lines. Cancer Res (2000) 0.92

Evaluation of cyclin D1 expression and its subcellular distribution in mouse tissues. J Anat (2004) 0.92

Inhibition of NMU-induced mammary tumorigenesis by dietary soy. Cancer Lett (2004) 0.90

Suppression of breast cancer growth and angiogenesis by an antisense oligodeoxynucleotide to p21(Waf1/Cip1). Cancer Lett (2003) 0.90

Genistein enhances N-nitrosomethylurea-induced rat mammary tumorigenesis. Cancer Lett (2005) 0.89

Validity of the DMBA-induced mammary cancer model for the study of human breast cancer. Int J Biol Markers (1988) 0.88

Citrus auraptene suppresses cyclin D1 and significantly delays N-methyl nitrosourea induced mammary carcinogenesis in female Sprague-Dawley rats. BMC Cancer (2009) 0.88

Serial transplantation of NMU-induced rat mammary tumors: a model of human breast cancer progression. Int J Cancer (2007) 0.87

Chemoprevention of NMU-induced rat mammary carcinoma with the combination of melatonin and 9-cis-retinoic acid. Cancer Lett (2001) 0.85

Increased expression of cyclin D1, cyclin E and p21(Cip1) associated with decreased expression of p27(Kip1) in chemically induced rat mammary carcinogenesis. Jpn J Cancer Res (2000) 0.84

p(21WAF1/CIP1) expression in breast cancers: associations with p53 and outcome. Breast Cancer Res Treat (2000) 0.83

Dehydroepiandrosterone inhibits the progression phase of mammary carcinogenesis by inducing cellular senescence via a p16-dependent but p53-independent mechanism. Breast Cancer Res (2005) 0.83

Exercise during puberty and NMU induced mammary tumorigenesis in rats. Breast Cancer Res Treat (1998) 0.83

The genetic components of susceptibility to breast cancer in the rat. Prog Exp Tumor Res (1999) 0.83

Crocetin inhibits cell cycle G1/S transition through suppressing cyclin D1 and elevating p27kip1 in vascular smooth muscle cells. Phytother Res (2010) 0.81

Regression of NMU-induced mammary tumors with the combination of melatonin and 9-cis-retinoic acid. Cancer Lett (2005) 0.81

Expression of cyclin Ds in relation to p53 status in human breast carcinomas. Virchows Arch (1998) 0.81

Alterations of the cell cycle regulators cyclin D1, cyclin A, p27, p21, p16, and pRb in apocrine metaplasia of the breast. Breast J (2009) 0.79

Influence of aging on multi-organ carcinogenesis in rats induced by N-methyl-N-nitrosourea. Jpn J Cancer Res (1993) 0.79

Prolactin, TNF alpha and nitric oxide expression in nitroso-N-methylurea-induced-mammary tumours. J Carcinog (2007) 0.79

Diphenyl diselenide supplementation delays the development of N-nitroso-N-methylurea-induced mammary tumors. Arch Toxicol (2007) 0.78

Immunobiological characterization of N -nitrosomethylurea-induced rat breast carcinomas: tumoral IL-10 expression as a possible immune escape mechanism. Breast Cancer Res Treat (2004) 0.78

MNU-induced carcinogenesis of rat mammary gland: effect of thyroid hormone on expression of retinoic acid receptors in tumours of mammary gland. Mol Cell Endocrinol (2005) 0.78

Specific enkephalin-degrading aminopeptidase activity in the HPT and HPO axes of rats with breast cancer induced by N-methyl nitrosourea. Regul Pept (2005) 0.78

Serum oxytocinase activity is related to tumor growth parameters in N-methyl nitrosourea induced rat breast cancer. Life Sci (2004) 0.78

Epidermal growth factor in NMU-induced mammary tumors in rats. Breast Cancer Res Treat (1998) 0.78

Comparative genomics of susceptibility to mammary carcinogenesis among inbred rat strains: role of reduced prolactin signaling in resistance of the Copenhagen strain. Carcinogenesis (2007) 0.78

Analysis of caspase activities in rat mammary tumours induced by N-methyl-nitrosourea. Oncol Rep (2008) 0.76

Tissue-specific resistance to cancer development in the rat: phenotypes of tumor-modifier genes. Carcinogenesis (2002) 0.76

Articles by these authors

Heterogeneous expression of CD32 and CD32-mediated growth suppression in human myeloma cells. Haematologica (2006) 1.42

Baicalein, a component of Scutellaria radix from Huang-Lian-Jie-Du-Tang (HLJDT), leads to suppression of proliferation and induction of apoptosis in human myeloma cells. Blood (2004) 1.26

Accelerated proliferation of myeloma cells by interleukin-6 cooperating with fibroblast growth factor receptor 3-mediated signals. Oncogene (2005) 0.91

Requirements of src family kinase activity associated with CD45 for myeloma cell proliferation by interleukin-6. Blood (2002) 0.87

Induction of multilineage markers in human myeloma cells and their down-regulation by interleukin 6. Int J Hematol (2007) 0.87

Evaluation of H3 histone methylation and colony formation in erythroid progenitors treated with thalidomide and sodium butyrate. Lab Hematol (2013) 0.87

Neoplastic bone marrow niche: hematopoietic and mesenchymal stem cells. Cell J (2011) 0.86

Growth mechanism of human myeloma cells by interleukin-6. Int J Hematol (2002) 0.83

Interleukin-6, CD45 and the src-kinases in myeloma cell proliferation. Leuk Lymphoma (2003) 0.83

The roles of miR-146a in the differentiation of Jurkat T-lymphoblasts. Hematology (2013) 0.83

miR-155 Down Regulation by LNA Inhibitor can Reduce Cell Growth and Proliferation in PC12 Cell Line. Avicenna J Med Biotechnol (2011) 0.82

A rapid translocation of CD45RO but not CD45RA to lipid rafts in IL-6-induced proliferation in myeloma. Blood (2004) 0.81

The High Yield Expansion and Megakaryocytic Differentiation of Human Umbilical Cord Blood CD133(+) Cells. Cell J (2011) 0.80

Generation of high-yield insulin producing cells from human bone marrow mesenchymal stem cells. Mol Biol Rep (2014) 0.79

IL-6-induced activation of MYC is responsible for the down-regulation of CD33 expression in CD33+ myeloma cells. Int J Hematol (2009) 0.79

Dehydroepiandrosterone can inhibit the proliferation of myeloma cells and the interleukin-6 production of bone marrow mononuclear cells from patients with myeloma. Cancer Res (2005) 0.79

Osteogenic inhibition in multiple myeloma. Cell J (2013) 0.79

CD19 expression and growth inhibition of tumours in human multiple myeloma. Leuk Lymphoma (2002) 0.78

Gene Expression Status and Methylation Pattern in Promoter of P15INK4b and P16INK4a in Cord Blood CD34 (+) Stem Cells. Iran J Basic Med Sci (2013) 0.77

The regulatory mechanism of IL-6-dependent proliferation of human myeloma cells. Hematology (2003) 0.75

Comparison of Expression Signature of Histone Deacetylases (HDACs) in Mesenchymal Stem Cells from Multiple Myeloma and Normal Donors. Asian Pac J Cancer Prev (2016) 0.75