Published in J Cell Sci on March 01, 2004
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TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science (2008) 14.09
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The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression. Nat Genet (2004) 3.86
IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy. Nat Genet (2007) 2.98
Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis. Nat Rev Neurol (2011) 2.73
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Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family. J Neurosci (2011) 1.56
Neurons expressing the highest levels of gamma-synuclein are unaffected by targeted inactivation of the gene. Mol Cell Biol (2003) 1.53
The antimicrobial effect of nitric oxide on the bacteria that cause nosocomial pneumonia in mechanically ventilated patients in the intensive care unit. Respir Care (2005) 1.50
Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice. J Neurochem (2004) 1.50
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Myosin VI and its interacting protein LMTK2 regulate tubule formation and transport to the endocytic recycling compartment. J Cell Sci (2007) 1.48
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Absence of alpha-synuclein affects dopamine metabolism and synaptic markers in the striatum of aging mice. Neurobiol Aging (2008) 1.41
Increased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synuclein. Eur J Neurosci (2008) 1.38
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Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments. J Cell Biol (2003) 1.24
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A fast and accurate procedure for deriving the Sholl profile in quantitative studies of neuronal morphology. J Neurosci Methods (2007) 1.21
The cellular and molecular pathology of the motor system in hereditary spastic paraparesis due to mutation of the spastin gene. J Neuropathol Exp Neurol (2003) 1.21
Molecular motors implicated in the axonal transport of tau and alpha-synuclein. J Cell Sci (2005) 1.20
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ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules. Hum Mol Genet (2013) 1.20
VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis. Hum Mol Genet (2011) 1.19
Mitogen-inducible gene 6 is an endogenous inhibitor of HGF/Met-induced cell migration and neurite growth. J Cell Biol (2005) 1.18
Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models. FEBS Lett (2009) 1.17
The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-kapp B signaling. J Cell Biol (2004) 1.17
Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport. Hum Mol Genet (2002) 1.16
Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta. J Neuropathol Exp Neurol (2002) 1.16
The active form of glycogen synthase kinase-3beta is associated with granulovacuolar degeneration in neurons in Alzheimer's disease. Acta Neuropathol (2001) 1.15
Dynamic association of tau with neuronal membranes is regulated by phosphorylation. Neurobiol Aging (2011) 1.13
Nuclear factor-kappaB activation via tyrosine phosphorylation of inhibitor kappaB-alpha is crucial for ciliary neurotrophic factor-promoted neurite growth from developing neurons. J Neurosci (2007) 1.12
Hereditary spastic paraparesis: disrupted intracellular transport associated with spastin mutation. Ann Neurol (2003) 1.11
Compromised paraspeckle formation as a pathogenic factor in FUSopathies. Hum Mol Genet (2013) 1.11
Phosphorylation of tau regulates its axonal transport by controlling its binding to kinesin. FASEB J (2008) 1.11
Reprogramming of tau alternative splicing by spliceosome-mediated RNA trans-splicing: implications for tauopathies. Proc Natl Acad Sci U S A (2005) 1.10
Minocycline reduces the development of abnormal tau species in models of Alzheimer's disease. FASEB J (2008) 1.08
The slow axonal transport of the microtubule-associated protein tau and the transport rates of different isoforms and mutants in cultured neurons. J Neurosci (2002) 1.08
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Homeodomain-interacting protein kinase-2 regulates apoptosis in developing sensory and sympathetic neurons. Curr Biol (2004) 1.05
p38alpha stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis. Mol Cell Neurosci (2004) 1.04
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Selective pattern of motor system damage in gamma-synuclein transgenic mice mirrors the respective pathology in amyotrophic lateral sclerosis. Neurobiol Dis (2012) 1.01
Tau phosphorylation affects its axonal transport and degradation. Neurobiol Aging (2013) 1.00
Identification of a novel, membrane-associated neuronal kinase, cyclin-dependent kinase 5/p35-regulated kinase. J Neurosci (2003) 1.00
HD-PTP and Alix share some membrane-traffic related proteins that interact with their Bro1 domains or proline-rich regions. Arch Biochem Biophys (2006) 1.00
HGF promotes survival and growth of maturing sympathetic neurons by PI-3 kinase- and MAP kinase-dependent mechanisms. Mol Cell Neurosci (2004) 1.00
Age-dependent axonal transport and locomotor changes and tau hypophosphorylation in a "P301L" tau knockin mouse. Neurobiol Aging (2011) 0.99
Developmental switch in NF-kappaB signalling required for neurite growth. Development (2009) 0.99
Developmental regulation of sensory neurite growth by the tumor necrosis factor superfamily member LIGHT. J Neurosci (2009) 0.98
Kinase activities increase during the development of tauopathy in htau mice. J Neurochem (2007) 0.98
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Gamma-synuclein is an adipocyte-neuron gene coordinately expressed with leptin and increased in human obesity. J Nutr (2008) 0.97
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