Published in J Cell Sci on March 01, 2004
Human African trypanosomiasis: pharmacological re-engagement with a neglected disease. Br J Pharmacol (2007) 2.96
The trypanosome flagellar pocket. Nat Rev Microbiol (2009) 2.07
The developmental cell biology of Trypanosoma brucei. J Cell Sci (2005) 1.84
Cold shock and regulation of surface protein trafficking convey sensitization to inducers of stage differentiation in Trypanosoma brucei. Genes Dev (2004) 1.72
Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes. Proc Natl Acad Sci U S A (2005) 1.58
Biogenesis of the trypanosome endo-exocytotic organelle is cytoskeleton mediated. PLoS Biol (2008) 1.48
Novel bilobe components in Trypanosoma brucei identified using proximity-dependent biotinylation. Eukaryot Cell (2012) 1.39
Functional analysis of TbARL1, an N-myristoylated Golgi protein essential for viability in bloodstream trypanosomes. J Cell Sci (2005) 1.30
Trypanosoma brucei ARF1 plays a central role in endocytosis and golgi-lysosome trafficking. Mol Biol Cell (2006) 1.26
Developmentally regulated sphingolipid synthesis in African trypanosomes. Mol Microbiol (2008) 1.26
Membrane domains and flagellar pocket boundaries are influenced by the cytoskeleton in African trypanosomes. Proc Natl Acad Sci U S A (2009) 1.08
Structure of the trypanosome haptoglobin-hemoglobin receptor and implications for nutrient uptake and innate immunity. Proc Natl Acad Sci U S A (2013) 1.06
Morphology of the trypanosome bilobe, a novel cytoskeletal structure. Eukaryot Cell (2012) 1.04
Endosomal localization of the serum resistance-associated protein in African trypanosomes confers human infectivity. Eukaryot Cell (2011) 1.02
Developmental variation in Rab11-dependent trafficking in Trypanosoma brucei. Eukaryot Cell (2005) 1.02
A function for a specific zinc metalloprotease of African trypanosomes. PLoS Pathog (2007) 1.02
High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis. PLoS Pathog (2011) 1.01
Role of AP-1 in developmentally regulated lysosomal trafficking in Trypanosoma brucei. Eukaryot Cell (2009) 0.98
The limits on trypanosomatid morphological diversity. PLoS One (2013) 0.98
The actomyosin ring recruits early secretory compartments to the division site in fission yeast. Mol Biol Cell (2008) 0.95
Modeling of the N-glycosylated transferrin receptor suggests how transferrin binding can occur within the surface coat of Trypanosoma brucei. PLoS Pathog (2012) 0.94
Blocking variant surface glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation. PLoS One (2009) 0.94
25 years of African trypanosome research: From description to molecular dissection and new drug discovery. Mol Biochem Parasitol (2015) 0.93
Human trypanolytic factor APOL1 forms pH-gated cation-selective channels in planar lipid bilayers: relevance to trypanosome lysis. Proc Natl Acad Sci U S A (2015) 0.91
A determination of the steady state lysosomal pH of bloodstream stage African trypanosomes. Mol Biochem Parasitol (2008) 0.90
Structure of the TbBILBO1 protein N-terminal domain from Trypanosoma brucei reveals an essential requirement for a conserved surface patch. J Biol Chem (2013) 0.90
More than meets the eye: understanding Trypanosoma brucei morphology in the tsetse. Front Cell Infect Microbiol (2013) 0.89
Architecture of a Host-Parasite Interface: Complex Targeting Mechanisms Revealed Through Proteomics. Mol Cell Proteomics (2015) 0.89
Requirement for acetyl-CoA carboxylase in Trypanosoma brucei is dependent upon the growth environment. Mol Microbiol (2011) 0.88
Life and times: synthesis, trafficking, and evolution of VSG. Trends Parasitol (2014) 0.88
Assembly mechanism of Trypanosoma brucei BILBO1, a multidomain cytoskeletal protein. J Biol Chem (2014) 0.87
Replication of the ERES:Golgi junction in bloodstream-form African trypanosomes. Mol Microbiol (2011) 0.87
Biochemical and genetic characterization of Trypanosoma cruzi N-myristoyltransferase. Biochem J (2014) 0.87
Trypanosome resistance to human innate immunity: targeting Achilles' heel. Trends Parasitol (2012) 0.87
Role of the Trypanosoma brucei natural cysteine peptidase inhibitor ICP in differentiation and virulence. Mol Microbiol (2007) 0.87
Late endosomal Rab7 regulates lysosomal trafficking of endocytic but not biosynthetic cargo in Trypanosoma brucei. Mol Microbiol (2011) 0.87
Characterization of the late endosomal ESCRT machinery in Trypanosoma brucei. Traffic (2013) 0.86
Evidence for recycling of invariant surface transmembrane domain proteins in African trypanosomes. Eukaryot Cell (2012) 0.86
How Does the VSG Coat of Bloodstream Form African Trypanosomes Interact with External Proteins? PLoS Pathog (2015) 0.86
Species-Specific Adaptations of Trypanosome Morphology and Motility to the Mammalian Host. PLoS Pathog (2016) 0.86
The plasma membrane of bloodstream-form African trypanosomes confers susceptibility and specificity to killing by hydrophobic peptides. J Biol Chem (2010) 0.85
The endocytic activity of the flagellar pocket in Trypanosoma brucei is regulated by an adjacent phosphatidylinositol phosphate kinase. J Cell Sci (2014) 0.85
The essential neutral sphingomyelinase is involved in the trafficking of the variant surface glycoprotein in the bloodstream form of Trypanosoma brucei. Mol Microbiol (2010) 0.85
Activity of trypanosome lytic factor: a novel component of innate immunity. Future Microbiol (2009) 0.84
Form and function in the trypanosomal secretory pathway. Curr Opin Microbiol (2012) 0.84
An extensive endoplasmic reticulum-localised glycoprotein family in trypanosomatids. Microb Cell (2014) 0.82
Sorting signals required for trafficking of the cysteine-rich acidic repetitive transmembrane protein in Trypanosoma brucei. Eukaryot Cell (2006) 0.82
Trypanosoma brucei: trypanosome-specific endoplasmic reticulum proteins involved in variant surface glycoprotein expression. Exp Parasitol (2010) 0.82
Using a non-image-based medium-throughput assay for screening compounds targeting N-myristoylation in intracellular Leishmania amastigotes. PLoS Negl Trop Dis (2014) 0.82
The molecular size of the extra-membrane domain influences the diffusion of the GPI-anchored VSG on the trypanosome plasma membrane. Sci Rep (2015) 0.82
Identification and characterization of an unusual class I myosin involved in vesicle traffic in Trypanosoma brucei. PLoS One (2010) 0.81
A MORN Repeat Protein Facilitates Protein Entry into the Flagellar Pocket of Trypanosoma brucei. Eukaryot Cell (2015) 0.81
Protozoacidal Trojan-Horse: use of a ligand-lytic peptide for selective destruction of symbiotic protozoa within termite guts. PLoS One (2014) 0.81
Rab5 Isoforms Specifically Regulate Different Modes of Endocytosis in Leishmania. J Biol Chem (2016) 0.80
Tryps and trips: cell trafficking across the 100-year-old blood-brain barrier. Trends Neurosci (2014) 0.79
Affinity is an important determinant of the anti-trypanosome activity of nanobodies. PLoS Negl Trop Dis (2012) 0.79
Proteomics on the rims: insights into the biology of the nuclear envelope and flagellar pocket of trypanosomes. Parasitology (2012) 0.79
TbARF1 influences lysosomal function but not endocytosis in procyclic stage Trypanosoma brucei. Mol Biochem Parasitol (2007) 0.79
Restless gossamers: antibody clearance by hydrodynamic flow forces generated at the surface of motile trypanosome parasites. Cell Host Microbe (2007) 0.78
Trypanosoma brucei gambiense adaptation to different mammalian sera is associated with VSG expression site plasticity. PLoS One (2013) 0.78
Transport through the Golgi in Trypanosoma brucei. Histochem Cell Biol (2013) 0.77
Exposure of Trypanosoma brucei to an N-acetylglucosamine-binding lectin induces VSG switching and glycosylation defects resulting in reduced infectivity. PLoS Negl Trop Dis (2015) 0.76
Maintaining the protective variant surface glycoprotein coat of African trypanosomes. Biochem Soc Trans (2005) 0.76
Cytosolic peroxidases protect the lysosome of bloodstream African trypanosomes from iron-mediated membrane damage. PLoS Pathog (2014) 0.76
A Novel Trypanosoma cruzi Protein Associated to the Flagellar Pocket of Replicative Stages and Involved in Parasite Growth. PLoS One (2015) 0.75
Blocking Synthesis of the Variant Surface Glycoprotein Coat in Trypanosoma brucei Leads to an Increase in Macrophage Phagocytosis Due to Reduced Clearance of Surface Coat Antibodies. PLoS Pathog (2016) 0.75
Two flagellar BAR domain proteins in Trypanosoma brucei with stage-specific regulation. Sci Rep (2016) 0.75
Form, Fabric, and Function of a Flagellum-Associated Cytoskeletal Structure. Cells (2015) 0.75
Controlling transferrin receptor trafficking with GPI-valence in bloodstream stage African trypanosomes. PLoS Pathog (2017) 0.75
Effects of dibucaine on the endocytic/exocytic pathways in Trypanosoma cruzi. Parasitol Res (2006) 0.75
Nanobodies As Tools to Understand, Diagnose, and Treat African Trypanosomiasis. Front Immunol (2017) 0.75
Efflux-dependent auxin gradients establish the apical-basal axis of Arabidopsis. Nature (2003) 8.75
Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy. Cancer Res (2008) 3.17
A comprehensive model for the cellular uptake of cationic cell-penetrating peptides. Traffic (2007) 3.01
The tubulin homologue FtsZ contributes to cell elongation by guiding cell wall precursor synthesis in Caulobacter crescentus. Mol Microbiol (2007) 2.97
Hydrodynamic flow-mediated protein sorting on the cell surface of trypanosomes. Cell (2007) 2.84
E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions. EMBO J (2005) 2.72
Metabolic priming by a secreted fungal effector. Nature (2011) 2.56
Control of crystal size and lattice formation by starmaker in otolith biomineralization. Science (2003) 2.35
Effects of multiple deletions of murein hydrolases on viability, septum cleavage, and sensitivity to large toxic molecules in Escherichia coli. J Bacteriol (2002) 2.29
Structure of a viral DNA gatekeeper at 10 A resolution by cryo-electron microscopy. EMBO J (2003) 2.16
Serum response factor is crucial for actin cytoskeletal organization and focal adhesion assembly in embryonic stem cells. J Cell Biol (2002) 1.99
Asterless is a centriolar protein required for centrosome function and embryo development in Drosophila. Curr Biol (2007) 1.99
Stage-specific differences in cell cycle control in Trypanosoma brucei revealed by RNA interference of a mitotic cyclin. J Biol Chem (2003) 1.99
Role of staphylococcal wall teichoic acid in targeting the major autolysin Atl. Mol Microbiol (2010) 1.82
Cold shock and regulation of surface protein trafficking convey sensitization to inducers of stage differentiation in Trypanosoma brucei. Genes Dev (2004) 1.72
Branching of Escherichia coli cells arises from multiple sites of inert peptidoglycan. J Bacteriol (2003) 1.71
Plant cytokinesis requires de novo secretory trafficking but not endocytosis. Curr Biol (2007) 1.67
Neuronal migration in the murine rostral migratory stream requires serum response factor. Proc Natl Acad Sci U S A (2005) 1.64
Determination of four sequential stages during microautophagy in vitro. J Biol Chem (2003) 1.60
Specific entry of Helicobacter pylori into cultured gastric epithelial cells via a zipper-like mechanism. Infect Immun (2002) 1.59
Cholesterol depletion in Mycobacterium avium-infected macrophages overcomes the block in phagosome maturation and leads to the reversible sequestration of viable mycobacteria in phagolysosome-derived autophagic vacuoles. Cell Microbiol (2006) 1.52
Drosophila Knickkopf and Retroactive are needed for epithelial tube growth and cuticle differentiation through their specific requirement for chitin filament organization. Development (2006) 1.50
Drosophila ankyrin 2 is required for synaptic stability. Neuron (2008) 1.50
Septin-dependent compartmentalization of the endoplasmic reticulum during yeast polarized growth. J Cell Biol (2005) 1.49
Zebrafish eda and edar mutants reveal conserved and ancestral roles of ectodysplasin signaling in vertebrates. PLoS Genet (2008) 1.48
Endocytosis of a glycosylphosphatidylinositol-anchored protein via clathrin-coated vesicles, sorting by default in endosomes, and exocytosis via RAB11-positive carriers. Mol Biol Cell (2003) 1.46
The Arabidopsis PILZ group genes encode tubulin-folding cofactor orthologs required for cell division but not cell growth. Genes Dev (2002) 1.45
Involvement of chitin in exoskeleton morphogenesis in Drosophila melanogaster. J Morphol (2005) 1.45
Cytotoxicity of single-wall carbon nanotubes on human fibroblasts. Toxicol In Vitro (2006) 1.43
Paracrine control of oligodendrocyte differentiation by SRF-directed neuronal gene expression. Nat Neurosci (2009) 1.41
The peptidoglycan sacculus of Myxococcus xanthus has unusual structural features and is degraded during glycerol-induced myxospore development. J Bacteriol (2008) 1.40
RhoGEF2 and the formin Dia control the formation of the furrow canal by directed actin assembly during Drosophila cellularisation. Development (2005) 1.37
Transformation of monomorphic and pleomorphic Trypanosoma brucei. Methods Mol Biol (2004) 1.37
A mutation in the silver gene leads to defects in melanosome biogenesis and alterations in the visual system in the zebrafish mutant fading vision. Dev Biol (2005) 1.35
Proteomic analysis of secreted membrane vesicles of archaeal Sulfolobus species reveals the presence of endosome sorting complex components. Extremophiles (2008) 1.34
The nucleoporin Nup188 controls passage of membrane proteins across the nuclear pore complex. J Cell Biol (2010) 1.33
Trypanosoma brucei Polo-like kinase is essential for basal body duplication, kDNA segregation and cytokinesis. Mol Microbiol (2007) 1.31
The epithelial cell adhesion molecule EpCAM is required for epithelial morphogenesis and integrity during zebrafish epiboly and skin development. PLoS Genet (2009) 1.29
Restricted Mobility of Cell Surface Proteins in the Polar Regions of Escherichia coli. J Bacteriol (2004) 1.26
Genetic analysis of fin development in zebrafish identifies furin and hemicentin1 as potential novel fraser syndrome disease genes. PLoS Genet (2010) 1.25
Accumulation of a GPI-anchored protein at the cell surface requires sorting at multiple intracellular levels. Traffic (2002) 1.23
Molecular interactions of yeast Neo1p, an essential member of the Drs2 family of aminophospholipid translocases, and its role in membrane trafficking within the endomembrane system. Mol Cell Biol (2004) 1.23
Duplicated genes with split functions: independent roles of protocadherin15 orthologues in zebrafish hearing and vision. Development (2005) 1.21
Procyclic Trypanosoma brucei do not use Krebs cycle activity for energy generation. J Biol Chem (2003) 1.20
Furrow-specific endocytosis during cytokinesis of zebrafish blastomeres. Exp Cell Res (2002) 1.20
Adenylate cyclases of Trypanosoma brucei inhibit the innate immune response of the host. Science (2012) 1.19
Mouse urinary peptides provide a molecular basis for genotype discrimination by nasal sensory neurons. Nat Commun (2013) 1.18
Material structure, stiffness, and adhesion: why attachment pads of the grasshopper (Tettigonia viridissima) adhere more strongly than those of the locust (Locusta migratoria) (Insecta: Orthoptera). J Comp Physiol A Neuroethol Sens Neural Behav Physiol (2006) 1.18
Analysis of a novel insect cell culture medium-based growth medium for Bartonella species. Appl Environ Microbiol (2008) 1.18
Cuticle differentiation during Drosophila embryogenesis. Arthropod Struct Dev (2006) 1.17
Drosophila MICAL regulates myofilament organization and synaptic structure. Mech Dev (2007) 1.17
Structure of the head of the Bartonella adhesin BadA. PLoS Pathog (2008) 1.17
Acetyl:succinate CoA-transferase in procyclic Trypanosoma brucei. Gene identification and role in carbohydrate metabolism. J Biol Chem (2004) 1.16
The gammaTuRC components Grip75 and Grip128 have an essential microtubule-anchoring function in the Drosophila germline. Development (2006) 1.15
Protein kinase involved in flagellar-length control. Eukaryot Cell (2003) 1.15
Self-assembling SAS-6 multimer is a core centriole building block. J Biol Chem (2010) 1.14
An evolutionary conserved region in the vasa 3'UTR targets RNA translation to the germ cells in the zebrafish. Curr Biol (2002) 1.14
Patchiness of murein insertion into the sidewall of Escherichia coli. Microbiology (2003) 1.13
Binding to pyruvylated compounds as an ancestral mechanism to anchor the outer envelope in primitive bacteria. Mol Microbiol (2004) 1.13
Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in Saccharomyces cerevisiae. Mol Biol Cell (2003) 1.12
Selection of reference genes for mRNA quantification in Trypanosoma brucei. Mol Biochem Parasitol (2010) 1.11
A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival. EMBO Mol Med (2010) 1.09
A mitochondrial NADH-dependent fumarate reductase involved in the production of succinate excreted by procyclic Trypanosoma brucei. J Biol Chem (2005) 1.09
beta-Catenin is not required for proliferation and differentiation of epidermal mouse keratinocytes. J Cell Sci (2002) 1.09
The zebrafish mutant lbk/vam6 resembles human multisystemic disorders caused by aberrant trafficking of endosomal vesicles. Development (2007) 1.06
Mutated otopetrin 1 affects the genesis of otoliths and the localization of Starmaker in zebrafish. Dev Genes Evol (2004) 1.06
"Tips and tricks" for high-pressure freezing of model systems. Methods Cell Biol (2010) 1.05
Spastic paraplegia mutation N256S in the neuronal microtubule motor KIF5A disrupts axonal transport in a Drosophila HSP model. PLoS Genet (2012) 1.05
Acetate produced in the mitochondrion is the essential precursor for lipid biosynthesis in procyclic trypanosomes. Proc Natl Acad Sci U S A (2009) 1.04
Zebrafish penner/lethal giant larvae 2 functions in hemidesmosome formation, maintenance of cellular morphology and growth regulation in the developing basal epidermis. Development (2005) 1.03
Origin and function of the two major tail proteins of bacteriophage SPP1. Mol Microbiol (2008) 1.03
Slc45a2 and V-ATPase are regulators of melanosomal pH homeostasis in zebrafish, providing a mechanism for human pigment evolution and disease. Pigment Cell Melanoma Res (2012) 1.03
The head of Bartonella adhesin A is crucial for host cell interaction of Bartonella henselae. Cell Microbiol (2008) 1.01
The membrane-bound histidine acid phosphatase TbMBAP1 is essential for endocytosis and membrane recycling in Trypanosoma brucei. J Cell Sci (2005) 1.01
The vacuolar transporter chaperone (VTC) complex is required for microautophagy. Mol Biol Cell (2006) 1.01
Hormonal regulation of mummy is needed for apical extracellular matrix formation and epithelial morphogenesis in Drosophila. Development (2006) 1.00
Fast lysis of Escherichia coli filament cells requires differentiation of potential division sites. Microbiology (2002) 1.00
Yeast Ysl2p, homologous to Sec7 domain guanine nucleotide exchange factors, functions in endocytosis and maintenance of vacuole integrity and interacts with the Arf-Like small GTPase Arl1p. Mol Cell Biol (2002) 0.99
Characterization of NE81, the first lamin-like nucleoskeleton protein in a unicellular organism. Mol Biol Cell (2011) 0.99
Lgl2 and E-cadherin act antagonistically to regulate hemidesmosome formation during epidermal development in zebrafish. Development (2009) 0.97
TbPDE1, a novel class I phosphodiesterase of Trypanosoma brucei. Eur J Biochem (2004) 0.97
SRF regulates Bcl-2 expression and promotes cell survival during murine embryonic development. EMBO J (2004) 0.97
Bacillus subtilis bacteriophage SPP1 hexameric DNA helicase, G40P, interacts with forked DNA. Nucleic Acids Res (2002) 0.97
Effects of benzoylphenylurea on chitin synthesis and orientation in the cuticle of the Drosophila larva. Eur J Cell Biol (2008) 0.97
Mycobacterium requires an all-around closely apposing phagosome membrane to maintain the maturation block and this apposition is re-established when it rescues itself from phagolysosomes. Cell Microbiol (2009) 0.96
The genome of the novel phage Rtp, with a rosette-like tail tip, is homologous to the genome of phage T1. J Bacteriol (2006) 0.96
ssDNA-dependent colocalization of adeno-associated virus Rep and herpes simplex virus ICP8 in nuclear replication domains. Nucleic Acids Res (2003) 0.96
The proneural gene ascl1a is required for endocrine differentiation and cell survival in the zebrafish adenohypophysis. Development (2006) 0.95
FraC/FraD-dependent intercellular molecular exchange in the filaments of a heterocyst-forming cyanobacterium, Anabaena sp. Mol Microbiol (2011) 0.95
The structure of E. coli IgG-binding protein D suggests a general model for bending and binding in trimeric autotransporter adhesins. Structure (2011) 0.95