Published in PLoS Genet on October 03, 2008
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An ancient gene network is co-opted for teeth on old and new jaws. PLoS Biol (2009) 1.60
A common variation in EDAR is a genetic determinant of shovel-shaped incisors. Am J Hum Genet (2009) 1.47
Skeletogenic fate of zebrafish cranial and trunk neural crest. PLoS One (2012) 1.42
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A recurrent regulatory change underlying altered expression and Wnt response of the stickleback armor plates gene EDA. Elife (2015) 1.07
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Parallel developmental genetic features underlie stickleback gill raker evolution. Evodevo (2014) 0.87
A rat model of hypohidrotic ectodermal dysplasia carries a missense mutation in the Edaradd gene. BMC Genet (2011) 0.85
Ectodysplasin regulates activator-inhibitor balance in murine tooth development through Fgf20 signaling. Development (2012) 0.85
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New tools for the identification of developmentally regulated enhancer regions in embryonic and adult zebrafish. Zebrafish (2013) 0.83
Distinct developmental genetic mechanisms underlie convergently evolved tooth gain in sticklebacks. Development (2015) 0.83
Fish is Fish: the use of experimental model species to reveal causes of skeletal diversity in evolution and disease. J Appl Ichthyol (2014) 0.83
Selection and constraint underlie irreversibility of tooth loss in cypriniform fishes. Proc Natl Acad Sci U S A (2014) 0.82
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Osteogenic programs during zebrafish fin regeneration. Bonekey Rep (2015) 0.81
Zebrafish Craniofacial Development: A Window into Early Patterning. Curr Top Dev Biol (2015) 0.80
Phenoscape: Identifying Candidate Genes for Evolutionary Phenotypes. Mol Biol Evol (2015) 0.78
Disappearing scales in carps: re-visiting Kirpichnikov's model on the genetics of scale pattern formation. PLoS One (2013) 0.78
Partially repeatable genetic basis of benthic adaptation in threespine sticklebacks. Evolution (2016) 0.77
Early development and replacement of the stickleback dentition. J Morphol (2016) 0.75
Re-epithelialization of cutaneous wounds in adult zebrafish combines mechanisms of wound closure in embryonic and adult mammals. Development (2016) 0.75
Ectodysplasin signalling genes and phenotypic evolution in sculpins (Cottus). Proc Biol Sci (2015) 0.75
How could fully scaled carps appear in natural waters in Madagascar? Proc Biol Sci (2016) 0.75
Evolution of the angiopoietin-like gene family in teleosts and their role in skin regeneration. BMC Evol Biol (2017) 0.75
Multiple pigment cell types contribute to the black, blue, and orange ornaments of male guppies (Poecilia reticulata). PLoS One (2014) 0.75
Parallelism and Epistasis in Skeletal Evolution Identified through Use of Phylogenomic Mapping Strategies. Mol Biol Evol (2015) 0.75
Developmental Toxicity of Zinc Oxide Nanoparticles to Zebrafish (Danio rerio): A Transcriptomic Analysis. PLoS One (2016) 0.75
Developing an ancient epithelial appendage: FGF signalling regulates early tail denticle formation in sharks. Evodevo (2017) 0.75
Tinkering signaling pathways by gain and loss of protein isoforms: the case of the EDA pathway regulator EDARADD. BMC Evol Biol (2015) 0.75
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Localizing recent adaptive evolution in the human genome. PLoS Genet (2007) 5.11
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Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function. Dev Biol (2001) 3.82
The genetic architecture of parallel armor plate reduction in threespine sticklebacks. PLoS Biol (2004) 3.46
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Involvement of a novel Tnf receptor homologue in hair follicle induction. Nat Genet (1999) 2.54
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A practical genome scan for population-specific strong selective sweeps that have reached fixation. PLoS One (2007) 2.35
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IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis. Nature (2004) 2.21
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A scan for genetic determinants of human hair morphology: EDAR is associated with Asian hair thickness. Hum Mol Genet (2007) 1.96
Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors. Science (2000) 1.95
The proximo-distal sequence of origin of the parts of the chick wing and the role of the ectoderm. J Exp Zool (1948) 1.86
The medaka rs-3 locus required for scale development encodes ectodysplasin-A receptor. Curr Biol (2001) 1.75
Generation of the primary hair follicle pattern. Proc Natl Acad Sci U S A (2006) 1.72
NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth. Development (2006) 1.66
Ectodysplasin signaling in development. Cytokine Growth Factor Rev (2003) 1.48
Enhanced ectodysplasin-A receptor (EDAR) signaling alters multiple fiber characteristics to produce the East Asian hair form. Hum Mutat (2008) 1.39
Edar/Eda interactions regulate enamel knot formation in tooth morphogenesis. Development (2000) 1.39
Scale development in fish: a review, with description of sonic hedgehog (shh) expression in the zebrafish (Danio rerio). Int J Dev Biol (2004) 1.38
Involvement of the sonic hedgehog, patched 1 and bmp2 genes in patterning of the zebrafish dermal fin rays. Development (1998) 1.37
Mutations in EDAR account for one-quarter of non-ED1-related hypohidrotic ectodermal dysplasia. Hum Mutat (2006) 1.37
The activation level of the TNF family receptor, Edar, determines cusp number and tooth number during tooth development. Dev Biol (2004) 1.36
The development of the paired fins in the zebrafish (Danio rerio). Mech Dev (1998) 1.30
Ectodysplasin is a collagenous trimeric type II membrane protein with a tumor necrosis factor-like domain and co-localizes with cytoskeletal structures at lateral and apical surfaces of cells. Hum Mol Genet (1999) 1.29
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The anhidrotic ectodermal dysplasia gene (EDA) undergoes alternative splicing and encodes ectodysplasin-A with deletion mutations in collagenous repeats. Hum Mol Genet (1998) 1.18
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Ectodysplasin is released by proteolytic shedding and binds to the EDAR protein. Hum Mol Genet (2001) 1.13
The crystal structures of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity. Structure (2003) 1.10
A novel missense mutation of the EDA gene in a Mongolian family with congenital hypodontia. J Hum Genet (2006) 1.10
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Formation of dermal skeletal and dental tissues in fish: a comparative and evolutionary approach. Biol Rev Camb Philos Soc (2003) 1.08
Ectodysplasin, Edar and TNFRSF19 are expressed in complementary and overlapping patterns during mouse embryogenesis. Gene Expr Patterns (2003) 1.06
Anterior duplication of the Sonic hedgehog expression pattern in the pectoral fin buds of zebrafish treated with retinoic acid. Dev Biol (1995) 1.05
The Edar subfamily in feather placode formation. Dev Biol (2007) 1.04
Constraints on utilization of the EDA-signaling pathway in threespine stickleback evolution. Evol Dev (2007) 1.03
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A novel Gln358Glu mutation in ectodysplasin A associated with X-linked dominant incisor hypodontia. Am J Med Genet A (2007) 1.02
Signaling and subcellular localization of the TNF receptor Edar. Exp Cell Res (2001) 1.01
Mutational spectrum of the ED1 gene in X-linked hypohidrotic ectodermal dysplasia. Eur J Hum Genet (2001) 0.99
The ectodysplasin pathway in feather tract development. Development (2005) 0.99
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dackel acts in the ectoderm of the zebrafish pectoral fin bud to maintain AER signaling. Development (2000) 0.99
Spatial and temporal patterns of cell death in limb bud mesoderm after apical ectodermal ridge removal. Dev Biol (1982) 0.97
EDAR mutation in autosomal dominant hypohidrotic ectodermal dysplasia in two Swedish families. BMC Med Genet (2006) 0.95
Modulation of epidermal cell shaping and extracellular matrix during caudal fin morphogenesis in the zebra fish Brachydanio rerio. J Embryol Exp Morphol (1985) 0.95
The mutation spectrum of the EDA gene in X-linked anhidrotic ectodermal dysplasia. Hum Mutat (2001) 0.95
Non-syndromic tooth agenesis in two Chinese families associated with novel missense mutations in the TNF domain of EDA (ectodysplasin A). PLoS One (2008) 0.91
Of ancient tales and hairless tails. Nat Genet (1999) 0.81
The incomplete inactivation of Fgf8 in the limb ectoderm affects the morphogenesis of the anterior autopod through BMP-mediated cell death. Dev Dyn (2008) 0.80
Efflux-dependent auxin gradients establish the apical-basal axis of Arabidopsis. Nature (2003) 8.75
The zebrafish reference genome sequence and its relationship to the human genome. Nature (2013) 8.52
Live imaging of neuronal degradation by microglia reveals a role for v0-ATPase a1 in phagosomal fusion in vivo. Cell (2008) 3.19
Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy. Cancer Res (2008) 3.17
A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor. Nature (2002) 3.15
A comprehensive model for the cellular uptake of cationic cell-penetrating peptides. Traffic (2007) 3.01
The tubulin homologue FtsZ contributes to cell elongation by guiding cell wall precursor synthesis in Caulobacter crescentus. Mol Microbiol (2007) 2.97
The African coelacanth genome provides insights into tetrapod evolution. Nature (2013) 2.78
Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution. Nat Genet (2013) 2.76
E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions. EMBO J (2005) 2.72
Metabolic priming by a secreted fungal effector. Nature (2011) 2.56
Control of crystal size and lattice formation by starmaker in otolith biomineralization. Science (2003) 2.35
Effects of multiple deletions of murein hydrolases on viability, septum cleavage, and sensitivity to large toxic molecules in Escherichia coli. J Bacteriol (2002) 2.29
Migration and function of a glial subtype in the vertebrate peripheral nervous system. Neuron (2002) 2.24
Serum response factor is crucial for actin cytoskeletal organization and focal adhesion assembly in embryonic stem cells. J Cell Biol (2002) 1.99
Asterless is a centriolar protein required for centrosome function and embryo development in Drosophila. Curr Biol (2007) 1.99
Kinetics of endocytosis and recycling of the GPI-anchored variant surface glycoprotein in Trypanosoma brucei. J Cell Sci (2004) 1.98
Convergent evolution in mechanical design of lamnid sharks and tunas. Nature (2004) 1.86
Role of staphylococcal wall teichoic acid in targeting the major autolysin Atl. Mol Microbiol (2010) 1.82
her1 and the notch pathway function within the oscillator mechanism that regulates zebrafish somitogenesis. Development (2002) 1.77
Branching of Escherichia coli cells arises from multiple sites of inert peptidoglycan. J Bacteriol (2003) 1.71
Formation of the adult pigment pattern in zebrafish requires leopard and obelix dependent cell interactions. Development (2003) 1.68
Plant cytokinesis requires de novo secretory trafficking but not endocytosis. Curr Biol (2007) 1.67
Neuronal migration in the murine rostral migratory stream requires serum response factor. Proc Natl Acad Sci U S A (2005) 1.64
Determination of four sequential stages during microautophagy in vitro. J Biol Chem (2003) 1.60
Specific entry of Helicobacter pylori into cultured gastric epithelial cells via a zipper-like mechanism. Infect Immun (2002) 1.59
Axon sorting in the optic tract requires HSPG synthesis by ext2 (dackel) and extl3 (boxer). Neuron (2004) 1.56
Towing of sensory axons by their migrating target cells in vivo. Nat Neurosci (2004) 1.50
Drosophila Knickkopf and Retroactive are needed for epithelial tube growth and cuticle differentiation through their specific requirement for chitin filament organization. Development (2006) 1.50
Drosophila ankyrin 2 is required for synaptic stability. Neuron (2008) 1.50
Septin-dependent compartmentalization of the endoplasmic reticulum during yeast polarized growth. J Cell Biol (2005) 1.49
Endocytosis of a glycosylphosphatidylinositol-anchored protein via clathrin-coated vesicles, sorting by default in endosomes, and exocytosis via RAB11-positive carriers. Mol Biol Cell (2003) 1.46
The Arabidopsis PILZ group genes encode tubulin-folding cofactor orthologs required for cell division but not cell growth. Genes Dev (2002) 1.45
Involvement of chitin in exoskeleton morphogenesis in Drosophila melanogaster. J Morphol (2005) 1.45
Cytotoxicity of single-wall carbon nanotubes on human fibroblasts. Toxicol In Vitro (2006) 1.43
Paracrine control of oligodendrocyte differentiation by SRF-directed neuronal gene expression. Nat Neurosci (2009) 1.41
The peptidoglycan sacculus of Myxococcus xanthus has unusual structural features and is degraded during glycerol-induced myxospore development. J Bacteriol (2008) 1.40
RhoGEF2 and the formin Dia control the formation of the furrow canal by directed actin assembly during Drosophila cellularisation. Development (2005) 1.37
A mutation in the silver gene leads to defects in melanosome biogenesis and alterations in the visual system in the zebrafish mutant fading vision. Dev Biol (2005) 1.35
Proteomic analysis of secreted membrane vesicles of archaeal Sulfolobus species reveals the presence of endosome sorting complex components. Extremophiles (2008) 1.34
The nucleoporin Nup188 controls passage of membrane proteins across the nuclear pore complex. J Cell Biol (2010) 1.33
Germ line control of female sex determination in zebrafish. Dev Biol (2008) 1.30
The epithelial cell adhesion molecule EpCAM is required for epithelial morphogenesis and integrity during zebrafish epiboly and skin development. PLoS Genet (2009) 1.29
Restricted Mobility of Cell Surface Proteins in the Polar Regions of Escherichia coli. J Bacteriol (2004) 1.26
Genetic analysis of fin development in zebrafish identifies furin and hemicentin1 as potential novel fraser syndrome disease genes. PLoS Genet (2010) 1.25
Accumulation of a GPI-anchored protein at the cell surface requires sorting at multiple intracellular levels. Traffic (2002) 1.23
Molecular interactions of yeast Neo1p, an essential member of the Drs2 family of aminophospholipid translocases, and its role in membrane trafficking within the endomembrane system. Mol Cell Biol (2004) 1.23
Iridophores and their interactions with other chromatophores are required for stripe formation in zebrafish. Development (2013) 1.22
On the embryonic origin of adult melanophores: the role of ErbB and Kit signalling in establishing melanophore stem cells in zebrafish. Development (2013) 1.22
Duplicated genes with split functions: independent roles of protocadherin15 orthologues in zebrafish hearing and vision. Development (2005) 1.21
Large-scale mapping of mutations affecting zebrafish development. BMC Genomics (2007) 1.21
Furrow-specific endocytosis during cytokinesis of zebrafish blastomeres. Exp Cell Res (2002) 1.20
Myosin-V regulates oskar mRNA localization in the Drosophila oocyte. Curr Biol (2009) 1.19
Analysis of a novel insect cell culture medium-based growth medium for Bartonella species. Appl Environ Microbiol (2008) 1.18
Material structure, stiffness, and adhesion: why attachment pads of the grasshopper (Tettigonia viridissima) adhere more strongly than those of the locust (Locusta migratoria) (Insecta: Orthoptera). J Comp Physiol A Neuroethol Sens Neural Behav Physiol (2006) 1.18
Cuticle differentiation during Drosophila embryogenesis. Arthropod Struct Dev (2006) 1.17
The maternal-effect gene futile cycle is essential for pronuclear congression and mitotic spindle assembly in the zebrafish zygote. Development (2003) 1.17
Drosophila MICAL regulates myofilament organization and synaptic structure. Mech Dev (2007) 1.17
Structure of the head of the Bartonella adhesin BadA. PLoS Pathog (2008) 1.17
The gammaTuRC components Grip75 and Grip128 have an essential microtubule-anchoring function in the Drosophila germline. Development (2006) 1.15
Self-assembling SAS-6 multimer is a core centriole building block. J Biol Chem (2010) 1.14
An evolutionary conserved region in the vasa 3'UTR targets RNA translation to the germ cells in the zebrafish. Curr Biol (2002) 1.14
Patchiness of murein insertion into the sidewall of Escherichia coli. Microbiology (2003) 1.13
Binding to pyruvylated compounds as an ancestral mechanism to anchor the outer envelope in primitive bacteria. Mol Microbiol (2004) 1.13
Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in Saccharomyces cerevisiae. Mol Biol Cell (2003) 1.12
Gamma-tubulin37C and gamma-tubulin ring complex protein 75 are essential for bicoid RNA localization during drosophila oogenesis. Dev Cell (2002) 1.12
Lgl2 executes its function as a tumor suppressor by regulating ErbB signaling in the zebrafish epidermis. PLoS Genet (2009) 1.10
A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival. EMBO Mol Med (2010) 1.09
beta-Catenin is not required for proliferation and differentiation of epidermal mouse keratinocytes. J Cell Sci (2002) 1.09
An F1 genetic screen for maternal-effect mutations affecting embryonic pattern formation in Drosophila melanogaster. Genetics (2004) 1.09
Duplication of fgfr1 permits Fgf signaling to serve as a target for selection during domestication. Curr Biol (2009) 1.08
Loss of schooling behavior in cavefish through sight-dependent and sight-independent mechanisms. Curr Biol (2013) 1.07
Bazooka is required for polarisation of the Drosophila anterior-posterior axis. Development (2010) 1.07
The zebrafish mutant lbk/vam6 resembles human multisystemic disorders caused by aberrant trafficking of endosomal vesicles. Development (2007) 1.06
Mutated otopetrin 1 affects the genesis of otoliths and the localization of Starmaker in zebrafish. Dev Genes Evol (2004) 1.06
transparent, a gene affecting stripe formation in Zebrafish, encodes the mitochondrial protein Mpv17 that is required for iridophore survival. Biol Open (2013) 1.06
"Tips and tricks" for high-pressure freezing of model systems. Methods Cell Biol (2010) 1.05
Modulation of Fgfr1a signaling in zebrafish reveals a genetic basis for the aggression-boldness syndrome. J Neurosci (2011) 1.05
Spastic paraplegia mutation N256S in the neuronal microtubule motor KIF5A disrupts axonal transport in a Drosophila HSP model. PLoS Genet (2012) 1.05
Zebrafish penner/lethal giant larvae 2 functions in hemidesmosome formation, maintenance of cellular morphology and growth regulation in the developing basal epidermis. Development (2005) 1.03
Slc45a2 and V-ATPase are regulators of melanosomal pH homeostasis in zebrafish, providing a mechanism for human pigment evolution and disease. Pigment Cell Melanoma Res (2012) 1.03
The head of Bartonella adhesin A is crucial for host cell interaction of Bartonella henselae. Cell Microbiol (2008) 1.01
chokh/rx3 specifies the retinal pigment epithelium fate independently of eye morphogenesis. Dev Biol (2005) 1.01
The vacuolar transporter chaperone (VTC) complex is required for microautophagy. Mol Biol Cell (2006) 1.01
Hormonal regulation of mummy is needed for apical extracellular matrix formation and epithelial morphogenesis in Drosophila. Development (2006) 1.00
Fast lysis of Escherichia coli filament cells requires differentiation of potential division sites. Microbiology (2002) 1.00
Yeast Ysl2p, homologous to Sec7 domain guanine nucleotide exchange factors, functions in endocytosis and maintenance of vacuole integrity and interacts with the Arf-Like small GTPase Arl1p. Mol Cell Biol (2002) 0.99
Genetic lineage labeling in zebrafish uncovers novel neural crest contributions to the head, including gill pillar cells. Development (2013) 0.99
Characterization of NE81, the first lamin-like nucleoskeleton protein in a unicellular organism. Mol Biol Cell (2011) 0.99
Convergence in feeding posture occurs through different genetic loci in independently evolved cave populations of Astyanax mexicanus. Proc Natl Acad Sci U S A (2013) 0.98
Lgl2 and E-cadherin act antagonistically to regulate hemidesmosome formation during epidermal development in zebrafish. Development (2009) 0.97
SRF regulates Bcl-2 expression and promotes cell survival during murine embryonic development. EMBO J (2004) 0.97
Effects of benzoylphenylurea on chitin synthesis and orientation in the cuticle of the Drosophila larva. Eur J Cell Biol (2008) 0.97