1
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Impaired cumulus mucification and female sterility in tumor necrosis factor-induced protein-6 deficient mice.
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Development
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2003
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2.16
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2
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Hyaluronan and homeostasis: a balancing act.
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J Biol Chem
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2001
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2.03
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3
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Structural basis for complement factor H linked age-related macular degeneration.
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J Exp Med
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2007
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2.02
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4
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TSG-6: a multifunctional protein associated with inflammation.
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J Cell Sci
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2003
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1.97
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5
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His-384 allotypic variant of factor H associated with age-related macular degeneration has different heparin binding properties from the non-disease-associated form.
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J Biol Chem
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2006
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1.79
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6
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PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization.
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Development
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2004
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1.68
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7
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Structures of the Cd44-hyaluronan complex provide insight into a fundamental carbohydrate-protein interaction.
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Nat Struct Mol Biol
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2007
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1.51
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8
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Characterization of complexes formed between TSG-6 and inter-alpha-inhibitor that act as intermediates in the covalent transfer of heavy chains onto hyaluronan.
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J Biol Chem
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2005
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1.51
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9
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The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells.
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J Biol Chem
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2007
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1.51
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10
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TSG-6 modulates the interaction between hyaluronan and cell surface CD44.
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J Biol Chem
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2004
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1.48
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11
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The link module from human TSG-6 inhibits neutrophil migration in a hyaluronan- and inter-alpha -inhibitor-independent manner.
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J Biol Chem
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2002
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1.39
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12
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Structure of the regulatory hyaluronan binding domain in the inflammatory leukocyte homing receptor CD44.
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Mol Cell
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2004
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1.38
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13
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Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina.
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J Biol Chem
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2010
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1.36
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14
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Analysis of CD44-hyaluronan interactions in an artificial membrane system: insights into the distinct binding properties of high and low molecular weight hyaluronan.
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J Biol Chem
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2010
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1.34
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15
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Disrupted function of tumor necrosis factor-alpha-stimulated gene 6 blocks cumulus cell-oocyte complex expansion.
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Endocrinology
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2003
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1.34
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16
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Structural characterization of PTX3 disulfide bond network and its multimeric status in cumulus matrix organization.
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J Biol Chem
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2008
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1.33
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17
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Shiga toxin activates complement and binds factor H: evidence for an active role of complement in hemolytic uremic syndrome.
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J Immunol
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2009
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1.29
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18
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The inflammation-associated protein TSG-6 cross-links hyaluronan via hyaluronan-induced TSG-6 oligomers.
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J Biol Chem
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2011
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1.23
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19
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TSG-6 potentiates the antitissue kallikrein activity of inter-alpha-inhibitor through bikunin release.
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Am J Respir Cell Mol Biol
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2006
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1.21
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20
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Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation.
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Mol Immunol
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2008
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1.21
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21
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Hyaluronan fragments/CD44 mediate oxidative stress-induced MUC5B up-regulation in airway epithelium.
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Am J Respir Cell Mol Biol
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2008
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1.18
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22
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Characterization of the interaction between tumor necrosis factor-stimulated gene-6 and heparin: implications for the inhibition of plasmin in extracellular matrix microenvironments.
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J Biol Chem
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2005
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1.16
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23
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Specificity of the tumor necrosis factor-induced protein 6-mediated heavy chain transfer from inter-alpha-trypsin inhibitor to hyaluronan: implications for the assembly of the cumulus extracellular matrix.
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J Biol Chem
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2004
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1.15
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24
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A novel allelic variant of the human TSG-6 gene encoding an amino acid difference in the CUB module. Chromosomal localization, frequency analysis, modeling, and expression.
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J Biol Chem
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2002
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1.13
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25
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The angiogenic inhibitor long pentraxin PTX3 forms an asymmetric octamer with two binding sites for FGF2.
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J Biol Chem
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2010
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1.13
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26
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Overexpression of hyaluronan synthase 2 alters hyaluronan distribution and function in proximal tubular epithelial cells.
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J Am Soc Nephrol
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2006
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1.11
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27
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TSG-6 binds via its CUB_C domain to the cell-binding domain of fibronectin and increases fibronectin matrix assembly.
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Matrix Biol
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2007
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1.11
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28
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Use of 15N-NMR to resolve molecular details in isotopically-enriched carbohydrates: sequence-specific observations in hyaluronan oligomers up to decasaccharides.
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Glycobiology
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2004
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1.09
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29
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Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions.
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J Immunol
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2013
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1.06
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30
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Towards a structure for a TSG-6.hyaluronan complex by modeling and NMR spectroscopy: insights into other members of the link module superfamily.
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J Biol Chem
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2005
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1.05
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31
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Inhibitory effects of TSG-6 Link module on leukocyte-endothelial cell interactions in vitro and in vivo.
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Microcirculation
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2004
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1.05
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32
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Hyaluronan binding properties of a CD44 chimera containing the link module of TSG-6.
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J Biol Chem
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2002
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1.05
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33
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Complement factor H and age-related macular degeneration: the role of glycosaminoglycan recognition in disease pathology.
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Biochem Soc Trans
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2010
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1.05
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34
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Expression and purification of functionally active hyaluronan-binding domains from human cartilage link protein, aggrecan and versican: formation of ternary complexes with defined hyaluronan oligosaccharides.
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J Biol Chem
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2004
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1.04
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35
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Biochemical characterization and function of complexes formed by hyaluronan and the heavy chains of inter-alpha-inhibitor (HC*HA) purified from extracts of human amniotic membrane.
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J Biol Chem
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2009
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1.04
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36
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The link module from ovulation- and inflammation-associated protein TSG-6 changes conformation on hyaluronan binding.
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J Biol Chem
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2003
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1.04
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37
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Monocyte-to-macrophage differentiation: synthesis and secretion of a complex extracellular matrix.
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J Biol Chem
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2012
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1.02
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38
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TSG-6 inhibits osteoclast activity via an autocrine mechanism and is functionally synergistic with osteoprotegerin.
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Arthritis Rheum
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2011
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1.02
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39
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TSG-6 regulates bone remodeling through inhibition of osteoblastogenesis and osteoclast activation.
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J Biol Chem
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2008
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1.02
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40
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Decreased expression of tumor necrosis factor-alpha-stimulated gene 6 in cumulus cells of the cyclooxygenase-2 and EP2 null mice.
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Endocrinology
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2003
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1.01
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41
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A method for the non-covalent immobilization of heparin to surfaces.
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Anal Biochem
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2004
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1.00
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42
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Associative and structural properties of the region of complement factor H encompassing the Tyr402His disease-related polymorphism and its interactions with heparin.
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J Mol Biol
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2007
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1.00
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43
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Versican-thrombospondin-1 binding in vitro and colocalization in microfibrils induced by inflammation on vascular smooth muscle cells.
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J Cell Sci
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2006
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0.99
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44
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Coregulation in human leukocytes of the long pentraxin PTX3 and TSG-6.
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J Leukoc Biol
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2009
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0.99
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45
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Selective inhibition of ADAMTS-1, -4 and -5 by catechin gallate esters.
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Eur J Biochem
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2003
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0.99
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46
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Constitutive expression of inter-α-inhibitor (IαI) family proteins and tumor necrosis factor-stimulated gene-6 (TSG-6) by human amniotic membrane epithelial and stromal cells supporting formation of the heavy chain-hyaluronan (HC-HA) complex.
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J Biol Chem
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2012
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0.98
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47
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Hyaluronan binding to link module of TSG-6 and to G1 domain of aggrecan is differently regulated by pH.
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J Biol Chem
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2008
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0.97
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48
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Mapping the differential distribution of glycosaminoglycans in the adult human retina, choroid, and sclera.
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Invest Ophthalmol Vis Sci
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2011
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0.96
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49
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The role of complement in age-related macular degeneration: heparan sulphate, a ZIP code for complement factor H?
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J Innate Immun
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2013
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0.96
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50
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The N-terminal module of thrombospondin-1 interacts with the link domain of TSG-6 and enhances its covalent association with the heavy chains of inter-alpha-trypsin inhibitor.
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J Biol Chem
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2005
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0.95
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51
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Induction of the hyaluronic acid-binding protein, tumor necrosis factor-stimulated gene-6, in cervical smooth muscle cells by tumor necrosis factor-alpha and prostaglandin E(2).
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Am J Pathol
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2002
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0.95
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52
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Transglutaminase-2: a new endostatin partner in the extracellular matrix of endothelial cells.
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Biochem J
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2010
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0.94
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53
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Development of a microtiter plate-based glycosaminoglycan array for the investigation of glycosaminoglycan-protein interactions.
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Glycobiology
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2009
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0.93
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54
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TSG-6 inhibits neutrophil migration via direct interaction with the chemokine CXCL8.
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J Immunol
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2014
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0.93
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55
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Long pentraxin 3/tumor necrosis factor-stimulated gene-6 interaction: a biological rheostat for fibroblast growth factor 2-mediated angiogenesis.
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Arterioscler Thromb Vasc Biol
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2012
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0.92
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56
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Articular cartilage proteoglycans as boundary lubricants: structure and frictional interaction of surface-attached hyaluronan and hyaluronan--aggrecan complexes.
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Biomacromolecules
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2011
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0.92
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57
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Inter-α-inhibitor impairs TSG-6-induced hyaluronan cross-linking.
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J Biol Chem
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2013
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0.90
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58
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A refined model for the TSG-6 link module in complex with hyaluronan: use of defined oligosaccharides to probe structure and function.
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J Biol Chem
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2014
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0.89
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59
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Hyaluronan and hyaluronan binding proteins are normal components of mouse pancreatic islets and are differentially expressed by islet endocrine cell types.
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J Histochem Cytochem
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2012
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0.88
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60
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Plasticity of the TSG-6 HA-binding loop and mobility in the TSG-6-HA complex revealed by NMR and X-ray crystallography.
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J Mol Biol
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2007
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0.88
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61
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Determining the molecular basis for the pH-dependent interaction between the link module of human TSG-6 and hyaluronan.
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J Biol Chem
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2007
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0.87
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62
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Implication of the oligomeric state of the N-terminal PTX3 domain in cumulus matrix assembly.
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Matrix Biol
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2011
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0.87
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63
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Identification and characterization of a novel interaction between pulmonary surfactant protein D and decorin.
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J Biol Chem
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2003
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0.86
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64
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Sulfation of the bikunin chondroitin sulfate chain determines heavy chain·hyaluronan complex formation.
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J Biol Chem
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2013
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0.86
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65
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Mapping the differential distribution of proteoglycan core proteins in the adult human retina, choroid, and sclera.
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Invest Ophthalmol Vis Sci
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2012
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0.85
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66
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The proteoglycan glycomatrix: a sugar microenvironment essential for complement regulation.
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Front Immunol
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2013
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0.84
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67
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Immobilization of heparan sulfate on electrospun meshes to support embryonic stem cell culture and differentiation.
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J Biol Chem
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2012
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0.83
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68
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Inhibition of hyaluronan synthesis restores immune tolerance during autoimmune insulitis.
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J Clin Invest
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2015
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0.82
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69
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Hyaluronan, TSG-6, and inter-α-inhibitor in periprosthetic breast capsules: reduced levels of free hyaluronan and TSG-6 expression in contracted capsules.
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Aesthet Surg J
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2011
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0.82
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70
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Fourier transform mass spectrometry to monitor hyaluronan-protein interactions: use of hydrogen/deuterium amide exchange.
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Rapid Commun Mass Spectrom
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2007
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0.81
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71
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Preparation and application of biologically active fluorescent hyaluronan oligosaccharides.
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Glycobiology
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2004
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0.80
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72
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Experimental evidence for all-or-none cooperative interactions between the G1-domain of versican and multivalent hyaluronan oligosaccharides.
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Matrix Biol
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2005
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0.78
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73
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Isolation and purification of versican and analysis of versican proteolysis.
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Methods Mol Biol
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2015
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0.78
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74
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Normal and shear interactions between hyaluronan-aggrecan complexes mimicking possible boundary lubricants in articular cartilage in synovial joints.
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Biomacromolecules
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2012
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0.78
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75
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A bug in CUB's clothing: similarity between clostridial CBMs and complement CUBs.
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Trends Microbiol
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2008
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0.76
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76
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Synthesis of tumor necrosis factor alpha-induced protein 6 in porcine preovulatory follicles: a study with A38 antibody.
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Biol Reprod
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2008
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0.75
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77
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Hyaluronan in immune processes.
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Adv Exp Med Biol
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2005
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0.75
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