Published in Mol Biotechnol on March 01, 2004
Genome sequencing in microfabricated high-density picolitre reactors. Nature (2005) 150.21
Ancient human genome sequence of an extinct Palaeo-Eskimo. Nature (2010) 7.51
Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras. Nat Biotechnol (2006) 6.30
Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder. Nat Genet (2011) 5.73
Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli. Science (2010) 4.96
An Aboriginal Australian genome reveals separate human dispersals into Asia. Science (2011) 4.84
Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation. Science (2006) 4.71
An index of substitution saturation and its application. Mol Phylogenet Evol (2003) 4.71
Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma. Nat Genet (2011) 3.66
FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis. Cancer Cell (2011) 3.58
Adhesive phase separation at the dentin interface under wet bonding conditions. J Biomed Mater Res (2002) 3.08
Manipulating surface states in topological insulator nanoribbons. Nat Nanotechnol (2011) 2.70
Large electrocaloric effect in ferroelectric polymers near room temperature. Science (2008) 2.66
Noninvasive characterization of epicardial activation in humans with diverse atrial fibrillation patterns. Circulation (2010) 2.57
Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1. Autophagy (2008) 2.38
Relationship of solvent to the photopolymerization process, properties, and structure in model dentin adhesives. J Biomed Mater Res A (2007) 2.26
High operative risk of cool-tip radiofrequency ablation for unresectable pancreatic head cancer. J Surg Oncol (2006) 2.19
Role of hyperphosphatemia and 1,25-dihydroxyvitamin D in vascular calcification and mortality in fibroblastic growth factor 23 null mice. J Am Soc Nephrol (2007) 2.16
Serologic survey of pandemic (H1N1) 2009 virus, Guangxi Province, China. Emerg Infect Dis (2009) 2.13
Overexpression of cyclin D1 promotes tumor cell growth and confers resistance to cisplatin-mediated apoptosis in an elastase-myc transgene-expressing pancreatic tumor cell line. Clin Cancer Res (2005) 2.13
The Arabidopsis NPR1 protein is a receptor for the plant defense hormone salicylic acid. Cell Rep (2012) 2.13
MicroRNA expression signatures of bladder cancer revealed by deep sequencing. PLoS One (2011) 2.10
Newcastle disease virus-based live attenuated vaccine completely protects chickens and mice from lethal challenge of homologous and heterologous H5N1 avian influenza viruses. J Virol (2006) 2.08
Bone marrow graft-versus-host disease: early destruction of hematopoietic niche after MHC-mismatched hematopoietic stem cell transplantation. Blood (2010) 2.04
DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination. Sci Signal (2010) 2.04
Microfluidic device for multimodal characterization of pancreatic islets. Lab Chip (2008) 1.99
Adhesive/Dentin interface: the weak link in the composite restoration. Ann Biomed Eng (2010) 1.96
P450 enzymes: their structure, reactivity, and selectivity-modeled by QM/MM calculations. Chem Rev (2010) 1.95
Ionizing radiation and busulfan induce premature senescence in murine bone marrow hematopoietic cells. Cancer Res (2003) 1.86
Milnacipran for the treatment of fibromyalgia in adults: a 15-week, multicenter, randomized, double-blind, placebo-controlled, multiple-dose clinical trial. Clin Ther (2008) 1.86
Pyrosequencing reveals highly diverse and species-specific microbial communities in sponges from the Red Sea. ISME J (2010) 1.84
Integrated profiling of microRNAs and mRNAs: microRNAs located on Xq27.3 associate with clear cell renal cell carcinoma. PLoS One (2010) 1.82
Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate. PLoS Pathog (2012) 1.79
A novel glucokinase activator modulates pancreatic islet and hepatocyte function. Endocrinology (2005) 1.75
Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition. J Clin Invest (2010) 1.74
Characterization of photopolymerization of dentin adhesives as a function of light source and irradiance. J Biomed Mater Res B Appl Biomater (2007) 1.73
Plasma microRNAs as novel biomarkers for early detection of lung cancer. Int J Clin Exp Pathol (2011) 1.73
Bariatric surgery reduces visceral adipose inflammation and improves endothelial function in type 2 diabetic mice. Arterioscler Thromb Vasc Biol (2011) 1.69
Complete biosynthesis of erythromycin A and designed analogs using E. coli as a heterologous host. Chem Biol (2010) 1.68
N'-[4-(Dimethyl-amino)benzyl-idene]benzohydrazide. Acta Crystallogr Sect E Struct Rep Online (2009) 1.68
Halogen bonding--a novel interaction for rational drug design? J Med Chem (2009) 1.68
Transitional cell carcinoma in renal transplant recipients: a single center experience. Int J Urol (2008) 1.67
Antiemetic placebo: reduce adverse drug interactions between chemotherapeutic agents and antiemetic drugs in cancer patients. Med Hypotheses (2007) 1.62
Comprehensive molecular etiology analysis of nonsyndromic hearing impairment from typical areas in China. J Transl Med (2009) 1.62
Alignment of molecular networks by integer quadratic programming. Bioinformatics (2007) 1.61
NOA: a novel Network Ontology Analysis method. Nucleic Acids Res (2011) 1.60
Nanophase separation of polymers exposed to simulated bonding conditions. J Biomed Mater Res B Appl Biomater (2009) 1.56
Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions. Proc Natl Acad Sci U S A (2003) 1.54
Efficacy, safety and tolerability of bosentan in Chinese patients with pulmonary arterial hypertension. J Heart Lung Transplant (2010) 1.54
Carbon monoxide protects against hyperoxia-induced endothelial cell apoptosis by inhibiting reactive oxygen species formation. J Biol Chem (2006) 1.53
Prediction of protein-RNA binding sites by a random forest method with combined features. Bioinformatics (2010) 1.52
Altered microRNA expression in patients with non-obstructive azoospermia. Reprod Biol Endocrinol (2009) 1.51
Composite tissue allograft transplantation of cephalocervical skin flap and two ears. Plast Reconstr Surg (2005) 1.47
The significance of bone marrow cell morphology and its correlation with cytogenetic features in the diagnosis of MDS-RA patients. Leuk Res (2009) 1.46
Insulin secretory deficiency and glucose intolerance in Rab3A null mice. J Biol Chem (2003) 1.46
Vertical stratification of microbial communities in the Red Sea revealed by 16S rDNA pyrosequencing. ISME J (2010) 1.45
The microtubule stabilizing agent laulimalide does not bind in the taxoid site, kills cells resistant to paclitaxel and epothilones, and may not require its epoxide moiety for activity. Biochemistry (2002) 1.45
Structural basis for processivity and single-strand specificity of RNase II. Mol Cell (2006) 1.44
On the origin of Lake Malawi cichlid species: a population genetic analysis of divergence. Proc Natl Acad Sci U S A (2005) 1.43
Structural basis and binding properties of the second bromodomain of Brd4 with acetylated histone tails. Biochemistry (2008) 1.43
Scrub typhus in previously unrecognized areas of endemicity in China. J Clin Microbiol (2010) 1.41
Members of the PHO1 gene family show limited functional redundancy in phosphate transfer to the shoot, and are regulated by phosphate deficiency via distinct pathways. Plant J (2007) 1.39
Clinical significance of IL-18 gene over-expression in AML. Leuk Res (2002) 1.39
Interfacial chemistry of moisture-aged class II composite restorations. J Biomed Mater Res B Appl Biomater (2006) 1.38
Identification of metastasis-associated proteins involved in gallbladder carcinoma metastasis by proteomic analysis and functional exploration of chloride intracellular channel 1. Cancer Lett (2009) 1.38
Prediction of the tissue-specificity of selective estrogen receptor modulators by using a single biochemical method. Proc Natl Acad Sci U S A (2008) 1.38
Synthesis and herbicidal activity of novel alpha,alpha,alpha-trifluoro-m-tolyl pyridazinone derivatives. Pest Manag Sci (2006) 1.37
Identification of MCAM/CD146 as the target antigen of a human monoclonal antibody that recognizes both epithelioid and sarcomatoid types of mesothelioma. Cancer Res (2009) 1.34
Disease-aging network reveals significant roles of aging genes in connecting genetic diseases. PLoS Comput Biol (2009) 1.32
The electrophysiological cardiac ventricular substrate in patients after myocardial infarction: noninvasive characterization with electrocardiographic imaging. J Am Coll Cardiol (2011) 1.32
Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K-Akt signaling. J Cell Biol (2008) 1.32
Effects of water content and initiator composition on photopolymerization of a model BisGMA/HEMA resin. Dent Mater (2007) 1.32
Soft-templated mesoporous carbon-carbon nanotube composites for high performance lithium-ion batteries. Adv Mater (2011) 1.32
Ionizing radiation and busulfan inhibit murine bone marrow cell hematopoietic function via apoptosis-dependent and -independent mechanisms. Exp Hematol (2003) 1.31
A study of cycling induced degradation mechanisms in Si nanocrystal memory devices. Nanotechnology (2011) 1.30
Preparation and Properties of Novel Dentin Adhesives with Esterase Resistance. J Appl Polym Sci Symp (2007) 1.29
The prevalence of canine Leishmania infantum infection in western China detected by PCR and serological tests. Parasit Vectors (2011) 1.27
Nonbonding interactions of organic halogens in biological systems: implications for drug discovery and biomolecular design. Phys Chem Chem Phys (2010) 1.27
Reactive oxygen species-mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to cirsimaritin-induced apoptosis in human gallbladder carcinoma GBC-SD cells. Cancer Lett (2010) 1.26
Angiotensin-(1-7) with thioether bridge: an angiotensin-converting enzyme-resistant, potent angiotensin-(1-7) analog. J Pharmacol Exp Ther (2008) 1.26
Identifying dysfunctional crosstalk of pathways in various regions of Alzheimer's disease brains. BMC Syst Biol (2010) 1.24
Cooperativity in virus neutralization by human monoclonal antibodies to two adjacent regions located at the amino terminus of hepatitis C virus E2 glycoprotein. J Virol (2012) 1.24
Reactive oxygen species and hematopoietic stem cell senescence. Int J Hematol (2011) 1.24
Predicting DNA- and RNA-binding proteins from sequences with kernel methods. J Theor Biol (2009) 1.23
Improved human pancreatic islet purification with the refined UIC-UB density gradient. Transplantation (2007) 1.22
Bacterial hosts for natural product production. Mol Pharm (2008) 1.22
Genotypes and mouse virulence of Toxoplasma gondii isolates from animals and humans in China. PLoS One (2013) 1.22
Mobilization of dendritic cell precursors into the circulation by administration of MIP-1alpha in mice. J Natl Cancer Inst (2004) 1.21
Higher isolation of NDM-1 producing Acinetobacter baumannii from the sewage of the hospitals in Beijing. PLoS One (2013) 1.20
Recent advances in the discovery and development of marine microbial natural products. Mar Drugs (2013) 1.20
Morphological and chemical characterization of bonding hydrophobic adhesive to dentin using ethanol wet bonding technique. Dent Mater (2009) 1.20
Piglets cloned from induced pluripotent stem cells. Cell Res (2012) 1.19
Replication of the association of the aspartic acid repeat polymorphism in the asporin gene with knee-osteoarthritis susceptibility in Han Chinese. J Hum Genet (2006) 1.19
Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice. Mol Cell Biol (2009) 1.19
Complete genome sequence of Bradyrhizobium sp. S23321: insights into symbiosis evolution in soil oligotrophs. Microbes Environ (2012) 1.19
Micromechanical analysis of dentin/adhesive interface by the finite element method. J Biomed Mater Res B Appl Biomater (2004) 1.19
Electrical detection of spin-polarized surface states conduction in (Bi(0.53)Sb(0.47))2Te3 topological insulator. Nano Lett (2014) 1.19
Gene function prediction using labeled and unlabeled data. BMC Bioinformatics (2008) 1.19
Coexistence of blaNDM-1 with the prevalent blaOXA23 and blaIMP in pan-drug resistant Acinetobacter baumannii isolates in China. Clin Infect Dis (2011) 1.18
Icariin, a natural flavonol glycoside, induces apoptosis in human hepatoma SMMC-7721 cells via a ROS/JNK-dependent mitochondrial pathway. Cancer Lett (2010) 1.18