Published in J Allergy Clin Immunol on March 01, 2004
Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer. Pharmacol Rev (2009) 2.30
Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria. Proc Natl Acad Sci U S A (2005) 1.95
Acute cobalt-induced lung injury and the role of hypoxia-inducible factor 1alpha in modulating inflammation. Toxicol Sci (2010) 1.53
The clinical relevance of maintaining the functional integrity of the stratum corneum in both healthy and disease-affected skin. J Clin Aesthet Dermatol (2011) 1.40
Infected atopic dermatitis lesions contain pharmacologic amounts of lipoteichoic acid. J Allergy Clin Immunol (2009) 1.31
The role of microorganisms in atopic dermatitis. Clin Exp Immunol (2006) 1.31
Toll-like receptors in the skin. Semin Immunopathol (2007) 1.27
Structural and functional evidence for the role of the TLR2 DD loop in TLR1/TLR2 heterodimerization and signaling. J Biol Chem (2006) 1.21
Toll-like receptor -1, -2, and -6 polymorphisms and pulmonary tuberculosis susceptibility: a systematic review and meta-analysis. PLoS One (2013) 1.19
Toll-like receptors in skin. Adv Dermatol (2008) 1.17
Innate and adaptive immune responses against Staphylococcus aureus skin infections. Semin Immunopathol (2011) 1.12
The role of endotoxin and its receptors in allergic disease. Ann Allergy Asthma Immunol (2005) 1.08
Toll-like receptor 9 modulates immune responses to Aspergillus fumigatus conidia in immunodeficient and allergic mice. Infect Immun (2008) 1.07
Antimicrobial peptides, skin infections, and atopic dermatitis. Semin Cutan Med Surg (2008) 1.06
R753Q polymorphism inhibits Toll-like receptor (TLR) 2 tyrosine phosphorylation, dimerization with TLR6, and recruitment of myeloid differentiation primary response protein 88. J Biol Chem (2012) 1.04
Host- and microbe determinants that may influence the success of S. aureus colonization. Front Cell Infect Microbiol (2012) 1.03
Allergy and the skin. Clin Exp Immunol (2008) 1.00
The infectious aspects of atopic dermatitis. Immunol Allergy Clin North Am (2010) 0.98
Association of toll-interacting protein gene polymorphisms with atopic dermatitis. BMC Dermatol (2007) 0.97
Toll-like receptor 2 is important for the T(H)1 response to cutaneous sensitization. J Allergy Clin Immunol (2009) 0.96
Genome-wide association analysis of canine atopic dermatitis and identification of disease related SNPs. Immunogenetics (2010) 0.93
Toll-like receptors: role in dermatological disease. Mediators Inflamm (2010) 0.93
Why is eczema herpeticum unexpectedly rare? Antiviral Res (2013) 0.90
Association of TLR4 Gene rs2149356 polymorphism with primary gouty arthritis in a case-control study. PLoS One (2013) 0.88
Topical corticosteroid application and the structural and functional integrity of the epidermal barrier. J Clin Aesthet Dermatol (2013) 0.88
Role of macrophages in the pathogenesis of atopic dermatitis. Mediators Inflamm (2013) 0.88
Impaired Toll-like receptor 2 signalling in monocytes from 5-year-old allergic children. Clin Exp Immunol (2009) 0.87
Do the placental barrier, parasite genotype and Toll-like receptor polymorphisms contribute to the course of primary infection with various Toxoplasma gondii genotypes in pregnant women? Eur J Clin Microbiol Infect Dis (2013) 0.82
Tissue eosinophilia in a mouse model of colitis is highly dependent on TLR2 and independent of mast cells. Am J Pathol (2010) 0.81
Skewed Helper T-Cell Responses to IL-12 Family Cytokines Produced by Antigen-Presenting Cells and the Genetic Background in Behcet's Disease. Genet Res Int (2013) 0.80
Genetic polymorphisms in Toll-like receptors among pediatric patients with renal parenchymal infections of different clinical severities. PLoS One (2013) 0.80
The role of innate immune signaling in the pathogenesis of atopic dermatitis and consequences for treatments. Semin Immunopathol (2015) 0.79
Allergic rhinitis and genetic components: focus on Toll-like receptors (TLRs) gene polymorphism. Appl Clin Genet (2010) 0.78
Expression of pattern recognition receptors in cholesteatoma. Eur Arch Otorhinolaryngol (2013) 0.78
Exacerbation of allergen-induced eczema in TLR4- and TRIF-deficient mice. J Immunol (2013) 0.77
Evidence for linkage of a new region (11p14) to eczema and allergic diseases. Hum Genet (2007) 0.76
Molecular Mechanisms of Cutaneous Inflammatory Disorder: Atopic Dermatitis. Int J Mol Sci (2016) 0.76
Atopic dermatitis and the stratum corneum: part 3: the immune system in atopic dermatitis. J Clin Aesthet Dermatol (2013) 0.76
Association of Toll-like receptors 2, 3, and 4 genes polymorphisms with periapical pathosis risk. Med Oral Patol Oral Cir Bucal (2016) 0.75
Trim32 Deficiency Enhances Th2 Immunity and Predisposes to Features of Atopic Dermatitis. J Invest Dermatol (2016) 0.75
Polymorphisms in Toll-like receptor genes are associated with vitiligo. Front Genet (2015) 0.75
Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med (2002) 9.14
HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway. J Biol Chem (2002) 4.03
The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily. Eur J Immunol (2003) 3.17
Histamine down-regulates IL-27 production in antigen-presenting cells. J Leukoc Biol (2012) 3.12
The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo. J Clin Invest (2005) 2.91
Standardizing double-blind, placebo-controlled oral food challenges: American Academy of Allergy, Asthma & Immunology-European Academy of Allergy and Clinical Immunology PRACTALL consensus report. J Allergy Clin Immunol (2012) 2.90
PD-L1 expression on tolerogenic APCs is controlled by STAT-3. Eur J Immunol (2011) 2.80
Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy. Nat Med (2003) 2.61
Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme. N Engl J Med (2015) 2.44
The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway. J Biol Chem (2002) 2.39
Early identification of atopy in the prediction of persistent asthma in children. Lancet (2008) 2.27
Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report. J Allergy Clin Immunol (2006) 2.00
Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells. J Biol Chem (2004) 1.86
Maternal TLR signaling is required for prenatal asthma protection by the nonpathogenic microbe Acinetobacter lwoffii F78. J Exp Med (2009) 1.79
Human inflammatory dendritic epidermal cells express a functional histamine H4 receptor. J Invest Dermatol (2008) 1.73
Cord blood allergen-specific IgE is associated with reduced IFN-gamma production by cord blood cells: the Protection against Allergy-Study in Rural Environments (PASTURE) Study. J Allergy Clin Immunol (2008) 1.68
Pan-neurotrophin receptor p75 contributes to neuronal hyperreactivity and airway inflammation in a murine model of experimental asthma. Am J Respir Cell Mol Biol (2003) 1.65
Monitoring immune modulation by nutrition in the general population: identifying and substantiating effects on human health. Br J Nutr (2013) 1.64
A comparison of oral methylprednisolone plus azathioprine or mycophenolate mofetil for the treatment of bullous pemphigoid. Arch Dermatol (2007) 1.59
Histamine upregulates keratinocyte MMP-9 production via the histamine H1 receptor. J Invest Dermatol (2008) 1.58
Differential recognition of TLR-dependent microbial ligands in human bronchial epithelial cells. J Immunol (2007) 1.53
Human keratinocytes express AIM2 and respond to dsDNA with IL-1β secretion. Exp Dermatol (2011) 1.53
Immunostimulatory CpG-DNA activates murine microglia. J Immunol (2002) 1.52
Epidemiological and immunological evidence for the hygiene hypothesis. Immunobiology (2007) 1.49
Compartmentalized production of CCL17 in vivo: strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen. J Exp Med (2003) 1.41
MS-based monitoring of proteolytic decay of synthetic reporter peptides for quality control of plasma and serum specimens. Am J Clin Pathol (2013) 1.40
Regulation of innate immunity by suppressor of cytokine signaling (SOCS) proteins. Immunobiology (2007) 1.38
Oculocutaneous albinism accompanied by minor morphologic stigmata and reduced number and function of NK cells. A new variant of NK cell defect? Eur J Pediatr (2008) 1.37
Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment. Immunology (2007) 1.35
Methodologic European external quality assurance for DNA sequencing: the EQUALseq program. Clin Chem (2006) 1.35
Differential effects of CpG-DNA in Toll-like receptor-2/-4/-9 tolerance and cross-tolerance. Immunology (2005) 1.34
Acinetobacter lwoffii and Lactococcus lactis strains isolated from farm cowsheds possess strong allergy-protective properties. J Allergy Clin Immunol (2007) 1.33
Expression of CD14 and Toll-like receptor 2 in farmers' and non-farmers' children. Lancet (2002) 1.33
Guidance for substantiating the evidence for beneficial effects of probiotics: current status and recommendations for future research. J Nutr (2010) 1.33
Allergic airway inflammation inhibits pulmonary antibacterial host defense. J Immunol (2006) 1.31
Activation of toll-like receptor 9 by DNA from different bacterial species. Infect Immun (2006) 1.29
Correlation of IL-31 serum levels with severity of atopic dermatitis. J Allergy Clin Immunol (2008) 1.28
Induction of suppressor of cytokine signaling-1 by Toxoplasma gondii contributes to immune evasion in macrophages by blocking IFN-gamma signaling. J Immunol (2006) 1.27
Role of food allergy in atopic dermatitis. Curr Opin Allergy Clin Immunol (2004) 1.27
Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells. J Immunol (2005) 1.27
Approaching clinical proteomics: current state and future fields of application in fluid proteomics. Clin Chem Lab Med (2009) 1.27
Quantitative detection of periodontopathogens by real-time PCR. J Microbiol Methods (2004) 1.26
Early nutrition and immunity - progress and perspectives. Br J Nutr (2006) 1.26
Sca1-derived cells are a source of myocardial renewal in the murine adult heart. Stem Cell Reports (2013) 1.25
Elimination of the cardiac natriuretic peptides B-type natriuretic peptide (BNP) and N-terminal proBNP by hemodialysis. Clin Chem (2004) 1.25
Airway epithelial cells produce neurotrophins and promote the survival of eosinophils during allergic airway inflammation. J Allergy Clin Immunol (2006) 1.23
Critical role of preconceptional immunization for protective and nonpathological specific immunity in murine neonates. J Immunol (2003) 1.23
NO2-induced airway inflammation is associated with progressive airflow limitation and development of emphysema-like lesions in C57bl/6 mice. Exp Toxicol Pathol (2005) 1.23
Modifications in small interfering RNA that separate immunostimulation from RNA interference. J Immunol (2008) 1.22
The course of allergen-induced leukocyte infiltration in human and experimental asthma. J Allergy Clin Immunol (2006) 1.22
IgG subclass concentrations in certified reference material 470 and reference values for children and adults determined with the binding site reagents. Clin Chem (2003) 1.21
EQUAL-quant: an international external quality assessment scheme for real-time PCR. Clin Chem (2006) 1.20
Guidance for substantiating the evidence for beneficial effects of probiotics: prevention and management of allergic diseases by probiotics. J Nutr (2010) 1.18
Monocyte chemoattractant protein 1, intercellular adhesion molecule 1, and vascular cell adhesion molecule 1 in exudative age-related macular degeneration. Arch Ophthalmol (2010) 1.16
Serum amyloid A as a prognostic marker in melanoma identified by proteomic profiling. J Clin Oncol (2009) 1.15
Cord blood cytokines are modulated by maternal farming activities and consumption of farm dairy products during pregnancy: the PASTURE Study. J Allergy Clin Immunol (2009) 1.15
DNA methylation of TH1/TH2 cytokine genes affects sensitization and progress of experimental asthma. J Allergy Clin Immunol (2012) 1.14
Blocking IL-15 prevents the induction of allergen-specific T cells and allergic inflammation in vivo. J Immunol (2005) 1.13
Brain-derived neurotrophic factor (BDNF) contributes to neuronal dysfunction in a model of allergic airway inflammation. Br J Pharmacol (2004) 1.12
Laboratory management of samples in biobanks: European consensus expert group report. Biopreserv Biobank (2010) 1.12
Levels of antibodies specific to tetanus toxoid, Haemophilus influenzae type b, and pneumococcal capsular polysaccharide in healthy children and adults. Clin Diagn Lab Immunol (2003) 1.12
Immunomodulatory effects of viral TLR ligands on experimental asthma depend on the additive effects of IL-12 and IL-10. J Immunol (2007) 1.12
L-carnosine, a substrate of carnosinase-1, influences glucose metabolism. Diabetes (2007) 1.11
High-density genotyping study identifies four new susceptibility loci for atopic dermatitis. Nat Genet (2013) 1.11
Investigation of contact allergy to dental metals in 206 patients. Contact Dermatitis (2009) 1.10
Risk factors for bacterial catheter colonization in regional anaesthesia. BMC Anesthesiol (2005) 1.10
Epigenetic regulation in murine offspring as a novel mechanism for transmaternal asthma protection induced by microbes. J Allergy Clin Immunol (2011) 1.10
Prenatal exposure to a farm environment modifies atopic sensitization at birth. J Allergy Clin Immunol (2008) 1.09
The human tumor suppressor CEACAM1 modulates apoptosis and is implicated in early colorectal tumorigenesis. Oncogene (2004) 1.07
Reduced rather than enhanced cholinergic airway constriction in mice with ablation of the large conductance Ca2+-activated K+ channel. FASEB J (2006) 1.07
Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma. J Exp Med (2009) 1.07
Human keratinocytes respond to interleukin-18: implication for the course of chronic inflammatory skin diseases. J Invest Dermatol (2005) 1.07
Development and clinical application of a LC-MS/MS method for simultaneous determination of various tyrosine kinase inhibitors in human plasma. Clin Chim Acta (2011) 1.07
Antagonism of TIM-1 blocks the development of disease in a humanized mouse model of allergic asthma. J Clin Invest (2010) 1.06
Stress enhances airway reactivity and airway inflammation in an animal model of allergic bronchial asthma. Psychosom Med (2003) 1.06
A comparison of oral methylprednisolone plus azathioprine or mycophenolate mofetil for the treatment of pemphigus. Arch Dermatol (2006) 1.06
DNA from periodontopathogenic bacteria is immunostimulatory for mouse and human immune cells. Infect Immun (2003) 1.05
Tumor necrosis factor-alpha and interleukin-6 regulate secretion of brain-derived neurotrophic factor in human monocytes. J Neuroimmunol (2004) 1.05
Cytokine concentration in aqueous humour of eyes with exudative age-related macular degeneration. Acta Ophthalmol (2012) 1.05
Selective depletion of Foxp3+ Treg during sensitization phase aggravates experimental allergic airway inflammation. Eur J Immunol (2010) 1.04
Long-term treatment of atopic dermatitis with pimecrolimus cream 1% in infants does not interfere with the development of protective antibodies after vaccination. J Am Acad Dermatol (2005) 1.03
Anti-ulcer treatment during pregnancy induces food allergy in mouse mothers and a Th2-bias in their offspring. FASEB J (2007) 1.03
The Toll-like receptor 2 R753Q mutation modifies cytokine production and Toll-like receptor expression in atopic dermatitis. J Allergy Clin Immunol (2008) 1.03
Kinetic of RelA activation controls magnitude of TLR-mediated IL-12p40 induction. J Immunol (2009) 1.03
Phosphodiester CpG oligonucleotides as adjuvants: polyguanosine runs enhance cellular uptake and improve immunostimulative activity of phosphodiester CpG oligonucleotides in vitro and in vivo. Immunology (2002) 1.03
Micro-CT based experimental liver imaging using a nanoparticulate contrast agent: a longitudinal study in mice. PLoS One (2011) 1.03
CEACAM1 modulates epidermal growth factor receptor--mediated cell proliferation. J Clin Invest (2004) 1.02